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The map label for this gene is thyX [H]

Identifier: 49186532

GI number: 49186532

Start: 3496700

End: 3497473

Strand: Reverse

Name: thyX [H]

Synonym: BAS3530

Alternate gene names: 49186532

Gene position: 3497473-3496700 (Counterclockwise)

Preceding gene: 49186533

Following gene: 49186531

Centisome position: 66.89

GC content: 40.57

Gene sequence:

>774_bases
ATGGAGAATTTAAATATGGATGTAAAGCTACTAGCACATACGCAATTATCTGAGGAATTTGTTAATTATTTATCTGTTGT
ATTTGGTATTGGAGATGAAGGCTTTGACCCTACCCATGGGCAAGTAGTAGCTTTATCGGCAATCCGTACGTGTTACTCGC
CAAATAAGCCTAGTAGGATTGTGTCTTTAGAGGGAGAGAAGTACTTCAAGGGCAAAGCAACTGATGGAAAGGGTGGAAAA
GAAGTAGATCGACTTATTAGACATATTGTAGGTTCGGGGCATGCCTCAACTCTGGAGCATCTAACATATACCTTTGCAGT
AGAAGGAGTTAGCAGAGCATTACTCGCTCAGTTAACACGTCACCGTGTAGGATTCAGTTACTCAGTCCAATCCCAAAGAT
ATGTACGCATGGGAAGTAATGATAAGATAGGCGGTTTTGATTATGTAGTGCCTGAAACAGTTAAGGCTAAAGGAGAACAA
GTAGTTAATGCTTACAACGAAATGATGTACAAACTCCAAAGTGGTTATGATCTACTTAGAACATTAGGAATTCCTGCTGA
GGATGCTCGTAGCGTACTTCCAAACGCAGCCGCAACTAACCTAGTCTTAACAGTCAATTTACGTGGGCTTTTAGATTTCT
ATAATAAGCGTCGAAAAGGGAAAGGTGCTCAAGCTGAAATTGCGGAGTTGGCAGAGCAATTAAGGCAAGAAGTTGTAAAA
GTTGAAAAGTGGGTAGACGAGTTTTTTTGGAAGTGGAAAGTAACAGAAGTCTAG

Upstream 100 bases:

>100_bases
AAATCCATTTTTATAATTCAAGTGACGAGCTTAATTTATAAGAAAGGACTAATTACAGTATATAAAAACTTGTCTAACAA
GGTTACAAATTCATTAAGAA

Downstream 100 bases:

>100_bases
AAAGATTACAAATAAAAGAGCAGCTAGCAAAAGCTAACTGCTCATCTCCAGGGGAATTGGAGACTGCTGTATCTATAGTA
TTGACGGAATATTGAGTTTT

Product: prophage LambdaBa01, thymidylate synthase-complementing protein

Products: NA

Alternate protein names: TS; TSase [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MENLNMDVKLLAHTQLSEEFVNYLSVVFGIGDEGFDPTHGQVVALSAIRTCYSPNKPSRIVSLEGEKYFKGKATDGKGGK
EVDRLIRHIVGSGHASTLEHLTYTFAVEGVSRALLAQLTRHRVGFSYSVQSQRYVRMGSNDKIGGFDYVVPETVKAKGEQ
VVNAYNEMMYKLQSGYDLLRTLGIPAEDARSVLPNAAATNLVLTVNLRGLLDFYNKRRKGKGAQAEIAELAEQLRQEVVK
VEKWVDEFFWKWKVTEV

Sequences:

>Translated_257_residues
MENLNMDVKLLAHTQLSEEFVNYLSVVFGIGDEGFDPTHGQVVALSAIRTCYSPNKPSRIVSLEGEKYFKGKATDGKGGK
EVDRLIRHIVGSGHASTLEHLTYTFAVEGVSRALLAQLTRHRVGFSYSVQSQRYVRMGSNDKIGGFDYVVPETVKAKGEQ
VVNAYNEMMYKLQSGYDLLRTLGIPAEDARSVLPNAAATNLVLTVNLRGLLDFYNKRRKGKGAQAEIAELAEQLRQEVVK
VEKWVDEFFWKWKVTEV
>Mature_257_residues
MENLNMDVKLLAHTQLSEEFVNYLSVVFGIGDEGFDPTHGQVVALSAIRTCYSPNKPSRIVSLEGEKYFKGKATDGKGGK
EVDRLIRHIVGSGHASTLEHLTYTFAVEGVSRALLAQLTRHRVGFSYSVQSQRYVRMGSNDKIGGFDYVVPETVKAKGEQ
VVNAYNEMMYKLQSGYDLLRTLGIPAEDARSVLPNAAATNLVLTVNLRGLLDFYNKRRKGKGAQAEIAELAEQLRQEVVK
VEKWVDEFFWKWKVTEV

Specific function: Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate [H]

COG id: COG1351

COG function: function code F; Predicted alternative thymidylate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thyX (flavin-dependent thymidylate synthase) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003669 [H]

Pfam domain/function: PF02511 Thy1 [H]

EC number: =2.1.1.148 [H]

Molecular weight: Translated: 28779; Mature: 28779

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENLNMDVKLLAHTQLSEEFVNYLSVVFGIGDEGFDPTHGQVVALSAIRTCYSPNKPSRI
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHCCCCCCCEE
VSLEGEKYFKGKATDGKGGKEVDRLIRHIVGSGHASTLEHLTYTFAVEGVSRALLAQLTR
EEECCCEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HRVGFSYSVQSQRYVRMGSNDKIGGFDYVVPETVKAKGEQVVNAYNEMMYKLQSGYDLLR
HHCCCEEECCCCHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGIPAEDARSVLPNAAATNLVLTVNLRGLLDFYNKRRKGKGAQAEIAELAEQLRQEVVK
HCCCCHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
VEKWVDEFFWKWKVTEV
HHHHHHHHHHHEEECCC
>Mature Secondary Structure
MENLNMDVKLLAHTQLSEEFVNYLSVVFGIGDEGFDPTHGQVVALSAIRTCYSPNKPSRI
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHCCCCCCCEE
VSLEGEKYFKGKATDGKGGKEVDRLIRHIVGSGHASTLEHLTYTFAVEGVSRALLAQLTR
EEECCCEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HRVGFSYSVQSQRYVRMGSNDKIGGFDYVVPETVKAKGEQVVNAYNEMMYKLQSGYDLLR
HHCCCEEECCCCHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGIPAEDARSVLPNAAATNLVLTVNLRGLLDFYNKRRKGKGAQAEIAELAEQLRQEVVK
HCCCCHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
VEKWVDEFFWKWKVTEV
HHHHHHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11792842 [H]