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The map label for this gene is serC

Identifier: 49186084

GI number: 49186084

Start: 3059921

End: 3061003

Strand: Reverse

Name: serC

Synonym: BAS3079

Alternate gene names: 49186084

Gene position: 3061003-3059921 (Counterclockwise)

Preceding gene: 49186085

Following gene: 49186083

Centisome position: 58.54

GC content: 36.2

Gene sequence:

>1083_bases
ATGGAGAGAGTGTATAATTTTTCAGCTGGACCATCAATACTCCCTTTGCCAGTTTTAGAAAAAGTGCAAAAGGAGCTTGT
AAATTATAACGGGACAGGCATGTCTATTATGGAAATGAGTCACCGATCTTCTTATTTTCAAAGTATTATAGATGAAGCGG
GTAGCTTACTTCGTGAATTAATGAACATTCCTGATGAGTATGAAGTATTGTTTTTACAAGGTGGTGCTTCATTACAATTC
TCTATGATACCGTTAAATTTAATGAATACGTATAAAAAAGCAGGGTACGTATTGACTGGTTCATGGTCTAAAAAGGCACT
GCAAGAAGCTGAAAAAGTTGGAGAAGTACAAGTGATTGCTTCTTCTGAAAATGAGAAGTTTACTACAATTCCTAAACTGG
ATGGTTTATTAGGCGATGAAAAACTAGATTATGTACATATAACAACGAATAATACAATAGAGGGTACGAAATATGTGGAC
ATTCCACATGTAGATAAAGTACCACTCGTTGCGGATATGTCCCCAAATATTTTATCAGAACGATATGATGTTTCAAAGTT
TGGTCTTATATATGCGGGAGCGCAAAAGAATCTAGGGCCAGCGGGCTTAACGATTGCAATTATAAAAAGAGATTTAATTG
GAGGAGCAGATCGTTATTGTCCTACAATGTTAAACTATGAAACTTACAGTAAAAATAACTCCTTATATAATACACTGCCG
TCCTTTAGTATTTACGTAACAAAACTTGTATTAGAGTGGTTAAAAGAGCAAGGCGGAGTATCTGCGATTGAAGAACAAAA
TAAAATGAAATCTTCACTTCTTTACAATTTCTTAGATGAATCAAAATTGCTTACTTCACCAGTTGATCCTGCGTATCGGT
CACTTATGAACATTCCGTTTACAACGCCGTCAGAAGAGCTGAACAATGAGTTTTTACAAAAAGCGAAAGAACGCGGCCTT
GTTACGTTAAAAGGACATCGATCAGTCGGTGGTATGCGCGCTAGTATTTACAATGCGATGCCAGTACAAGGCGTACAGCA
ATTGGTAAATTATATGAAGGAATTTGAGCTTGAGAATAGATAG

Upstream 100 bases:

>100_bases
CCGTAATAATAGAAAACAAATTGACCGTGTCTTGTATTGTAGGGTATAATTCAGAAAGTTTAAAAAATAAAAGATGAGAA
ATAGGGAGGTTATTAGGGTG

Downstream 100 bases:

>100_bases
GGAGATGGGGATATGTTTCGTGTTCAAACGTTAAATCAAATAGCAGAAAAAGGTTTGCAAGTACTTGGCGGAGAGCGTTA
TGAAGTAGGGGAGAGAATCA

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MERVYNFSAGPSILPLPVLEKVQKELVNYNGTGMSIMEMSHRSSYFQSIIDEAGSLLRELMNIPDEYEVLFLQGGASLQF
SMIPLNLMNTYKKAGYVLTGSWSKKALQEAEKVGEVQVIASSENEKFTTIPKLDGLLGDEKLDYVHITTNNTIEGTKYVD
IPHVDKVPLVADMSPNILSERYDVSKFGLIYAGAQKNLGPAGLTIAIIKRDLIGGADRYCPTMLNYETYSKNNSLYNTLP
SFSIYVTKLVLEWLKEQGGVSAIEEQNKMKSSLLYNFLDESKLLTSPVDPAYRSLMNIPFTTPSEELNNEFLQKAKERGL
VTLKGHRSVGGMRASIYNAMPVQGVQQLVNYMKEFELENR

Sequences:

>Translated_360_residues
MERVYNFSAGPSILPLPVLEKVQKELVNYNGTGMSIMEMSHRSSYFQSIIDEAGSLLRELMNIPDEYEVLFLQGGASLQF
SMIPLNLMNTYKKAGYVLTGSWSKKALQEAEKVGEVQVIASSENEKFTTIPKLDGLLGDEKLDYVHITTNNTIEGTKYVD
IPHVDKVPLVADMSPNILSERYDVSKFGLIYAGAQKNLGPAGLTIAIIKRDLIGGADRYCPTMLNYETYSKNNSLYNTLP
SFSIYVTKLVLEWLKEQGGVSAIEEQNKMKSSLLYNFLDESKLLTSPVDPAYRSLMNIPFTTPSEELNNEFLQKAKERGL
VTLKGHRSVGGMRASIYNAMPVQGVQQLVNYMKEFELENR
>Mature_360_residues
MERVYNFSAGPSILPLPVLEKVQKELVNYNGTGMSIMEMSHRSSYFQSIIDEAGSLLRELMNIPDEYEVLFLQGGASLQF
SMIPLNLMNTYKKAGYVLTGSWSKKALQEAEKVGEVQVIASSENEKFTTIPKLDGLLGDEKLDYVHITTNNTIEGTKYVD
IPHVDKVPLVADMSPNILSERYDVSKFGLIYAGAQKNLGPAGLTIAIIKRDLIGGADRYCPTMLNYETYSKNNSLYNTLP
SFSIYVTKLVLEWLKEQGGVSAIEEQNKMKSSLLYNFLDESKLLTSPVDPAYRSLMNIPFTTPSEELNNEFLQKAKERGL
VTLKGHRSVGGMRASIYNAMPVQGVQQLVNYMKEFELENR

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily

Homologues:

Organism=Homo sapiens, GI17402893, Length=361, Percent_Identity=47.0914127423823, Blast_Score=334, Evalue=1e-91,
Organism=Homo sapiens, GI10863955, Length=356, Percent_Identity=41.8539325842697, Blast_Score=281, Evalue=8e-76,
Organism=Escherichia coli, GI1787136, Length=366, Percent_Identity=42.6229508196721, Blast_Score=310, Evalue=7e-86,
Organism=Caenorhabditis elegans, GI17506897, Length=360, Percent_Identity=45, Blast_Score=322, Evalue=2e-88,
Organism=Saccharomyces cerevisiae, GI6324758, Length=391, Percent_Identity=41.1764705882353, Blast_Score=289, Evalue=6e-79,
Organism=Drosophila melanogaster, GI21356589, Length=363, Percent_Identity=48.2093663911846, Blast_Score=336, Evalue=1e-92,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SERC_BACAA (C3P210)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002867493.1
- ProteinModelPortal:   C3P210
- SMR:   C3P210
- EnsemblBacteria:   EBBACT00000126032
- GeneID:   7849513
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_3356
- GeneTree:   EBGT00050000002587
- ProtClustDB:   PRK05355
- GO:   GO:0005737
- HAMAP:   MF_00160
- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- PIRSF:   PIRSF000525
- TIGRFAMs:   TIGR01364

Pfam domain/function: PF00266 Aminotran_5; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.52

Molecular weight: Translated: 40349; Mature: 40349

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: BINDING 43-43 BINDING 103-103 BINDING 153-153 BINDING 173-173 BINDING 196-196

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERVYNFSAGPSILPLPVLEKVQKELVNYNGTGMSIMEMSHRSSYFQSIIDEAGSLLREL
CCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MNIPDEYEVLFLQGGASLQFSMIPLNLMNTYKKAGYVLTGSWSKKALQEAEKVGEVQVIA
HCCCCCEEEEEEECCCCEEEEEECHHHHHHHHHCCEEEECCCHHHHHHHHHHCCCEEEEE
SSENEKFTTIPKLDGLLGDEKLDYVHITTNNTIEGTKYVDIPHVDKVPLVADMSPNILSE
CCCCCCEEECCHHHCCCCCCCCCEEEEEECCEECCCEEECCCCCCCCCEEECCCCHHHHH
RYDVSKFGLIYAGAQKNLGPAGLTIAIIKRDLIGGADRYCPTMLNYETYSKNNSLYNTLP
HCCHHHCCEEEECCCCCCCCCCEEEEEEHHHHCCCCCHHCCHHCCCCCCCCCCCHHHCCC
SFSIYVTKLVLEWLKEQGGVSAIEEQNKMKSSLLYNFLDESKLLTSPVDPAYRSLMNIPF
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHCCCC
TTPSEELNNEFLQKAKERGLVTLKGHRSVGGMRASIYNAMPVQGVQQLVNYMKEFELENR
CCCHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MERVYNFSAGPSILPLPVLEKVQKELVNYNGTGMSIMEMSHRSSYFQSIIDEAGSLLREL
CCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MNIPDEYEVLFLQGGASLQFSMIPLNLMNTYKKAGYVLTGSWSKKALQEAEKVGEVQVIA
HCCCCCEEEEEEECCCCEEEEEECHHHHHHHHHCCEEEECCCHHHHHHHHHHCCCEEEEE
SSENEKFTTIPKLDGLLGDEKLDYVHITTNNTIEGTKYVDIPHVDKVPLVADMSPNILSE
CCCCCCEEECCHHHCCCCCCCCCEEEEEECCEECCCEEECCCCCCCCCEEECCCCHHHHH
RYDVSKFGLIYAGAQKNLGPAGLTIAIIKRDLIGGADRYCPTMLNYETYSKNNSLYNTLP
HCCHHHCCEEEECCCCCCCCCCEEEEEEHHHHCCCCCHHCCHHCCCCCCCCCCCHHHCCC
SFSIYVTKLVLEWLKEQGGVSAIEEQNKMKSSLLYNFLDESKLLTSPVDPAYRSLMNIPF
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHCCCC
TTPSEELNNEFLQKAKERGLVTLKGHRSVGGMRASIYNAMPVQGVQQLVNYMKEFELENR
CCCHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA