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The map label for this gene is ydfD [H]

Identifier: 49185853

GI number: 49185853

Start: 2821303

End: 2822745

Strand: Direct

Name: ydfD [H]

Synonym: BAS2847

Alternate gene names: 49185853

Gene position: 2821303-2822745 (Clockwise)

Preceding gene: 49185852

Following gene: 49185855

Centisome position: 53.96

GC content: 38.67

Gene sequence:

>1443_bases
ATGGAATGGAAACTAGATAGTGACAGTAAAATCCCTATTTATCAGCAAGTTGTTGACTTTATCGAGAAACGTATTACATA
CGGGGAACTTCCTCCAGGTAGCTTTCTACCTTCTGAACGGAAATTAGCTACACAGTTAAATGTAAACCGTAGTACGGTAA
CGACTGCTTATAATGAATTACGTGCTATGGGAATTGTAGAAAGTACGACTGGTAAAGGAACACGCGTGAGTACACATATG
TGGGGCGTTTCTCCGACATTAACGCCGAACTGGAGGAATTTCGTAGAAGGTGGTACATTTTTACCAAACTTACCGTTACT
TCGTCATATTCGAGCGGAAGTACAACAAAATGAAAATATTATTGATTTCGCAAACGGAGAACTCGGTTGTAACCTCTATC
CTCACGATCAACTACAAACGATTTTACGAGAACAACCGTTAACGCACTCATTAAGTTACGATCATCCGCAAGGGTACCTC
CCGCTAAGACAAGCGGTAGTAAAATATATGAAAGAATATTTAAAAGTTGAAGCGACTGAACAATCGATTATGATTACATC
TGGTGCACAGCAAGCCTTGCACCTTATCGTACAATGTTTATTAAATCCGGGTGATGCTGTTGCTTTCGAAAGTCCTTCAC
ACTGTTATTCCCTGCCATTATTCCAATCAGCAGGTATTCGTATTTTCCCATTACCTGTCGATGAACACGGTATTAATCCG
GATGATGTGCAAGAGCTATATAGAAAGCATCGTATTAAAATGATTTTTTTAAATCCAAACTTCCAAAATCCTACGGGCAC
AATGCTGCATCCAAACCGTAGAAAAAAACTATTATCACTTTGTGCAGACTTACGAATTGCGATTGTGGAAGATGATCCGT
CTAGTTTACTTACGTTAGAAAAGAAACAACCTTGCCCTACTTTGAAATCGATTGATGAAAATGGAACTGTTATCTATGTA
CATTCTTTATCAAAAATGATTGCACCGGGATTACGAGTTGGTTGGCTTGTCGCCCCACAATCGGTAGTAGAAAGGTTATC
TGACGCACGACATCAAATGGAATTAGGTATGAGCATTTTCCCACAGTGGCTTATGCAGCAATTTTTCGAAACTGTACCTT
TTCAGTCTCATATCGTACCGTTACGAAAACAATTAACAGAAAAAAGAGACGTTATCGTTCGCGCCTTAAATGAGCAACTT
CACGATAAAATCTCTTTTTCAAATCCGACCGGTGGTATATACATATGGGGAAAATTAAAAGAACCGATAAACGAAAAACA
ACTTATTATGCAAAGTTTAAAACAAGAAATCGCCTTTATGCCGGGGAGTATTTTCGGCGCGAAAGATGGTTATATTCGTT
TATCTTATGGAAAAGTGAATATTGATCAAATTGAGGAAGGGATTTCTCGCTTGCGTGAGGCTATTTTGGTTTGTGAAAAG
TAA

Upstream 100 bases:

>100_bases
ATAGTAAAATTGGCTGGATATAACACCGTCCAATTGGCTGTTTTTTTACCCAGCCAATTTGCTATACTGGATTTATATAA
GAGATACGGAGGCACTTTTT

Downstream 100 bases:

>100_bases
CTTATGATAAAAGGATCTCGTTTGACAAAACCTAAATCTACCATTATCATCAACACGAACCTAGTTATAGGAGTGATACC
AATGAAAATCTATGTTGATG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MEWKLDSDSKIPIYQQVVDFIEKRITYGELPPGSFLPSERKLATQLNVNRSTVTTAYNELRAMGIVESTTGKGTRVSTHM
WGVSPTLTPNWRNFVEGGTFLPNLPLLRHIRAEVQQNENIIDFANGELGCNLYPHDQLQTILREQPLTHSLSYDHPQGYL
PLRQAVVKYMKEYLKVEATEQSIMITSGAQQALHLIVQCLLNPGDAVAFESPSHCYSLPLFQSAGIRIFPLPVDEHGINP
DDVQELYRKHRIKMIFLNPNFQNPTGTMLHPNRRKKLLSLCADLRIAIVEDDPSSLLTLEKKQPCPTLKSIDENGTVIYV
HSLSKMIAPGLRVGWLVAPQSVVERLSDARHQMELGMSIFPQWLMQQFFETVPFQSHIVPLRKQLTEKRDVIVRALNEQL
HDKISFSNPTGGIYIWGKLKEPINEKQLIMQSLKQEIAFMPGSIFGAKDGYIRLSYGKVNIDQIEEGISRLREAILVCEK

Sequences:

>Translated_480_residues
MEWKLDSDSKIPIYQQVVDFIEKRITYGELPPGSFLPSERKLATQLNVNRSTVTTAYNELRAMGIVESTTGKGTRVSTHM
WGVSPTLTPNWRNFVEGGTFLPNLPLLRHIRAEVQQNENIIDFANGELGCNLYPHDQLQTILREQPLTHSLSYDHPQGYL
PLRQAVVKYMKEYLKVEATEQSIMITSGAQQALHLIVQCLLNPGDAVAFESPSHCYSLPLFQSAGIRIFPLPVDEHGINP
DDVQELYRKHRIKMIFLNPNFQNPTGTMLHPNRRKKLLSLCADLRIAIVEDDPSSLLTLEKKQPCPTLKSIDENGTVIYV
HSLSKMIAPGLRVGWLVAPQSVVERLSDARHQMELGMSIFPQWLMQQFFETVPFQSHIVPLRKQLTEKRDVIVRALNEQL
HDKISFSNPTGGIYIWGKLKEPINEKQLIMQSLKQEIAFMPGSIFGAKDGYIRLSYGKVNIDQIEEGISRLREAILVCEK
>Mature_480_residues
MEWKLDSDSKIPIYQQVVDFIEKRITYGELPPGSFLPSERKLATQLNVNRSTVTTAYNELRAMGIVESTTGKGTRVSTHM
WGVSPTLTPNWRNFVEGGTFLPNLPLLRHIRAEVQQNENIIDFANGELGCNLYPHDQLQTILREQPLTHSLSYDHPQGYL
PLRQAVVKYMKEYLKVEATEQSIMITSGAQQALHLIVQCLLNPGDAVAFESPSHCYSLPLFQSAGIRIFPLPVDEHGINP
DDVQELYRKHRIKMIFLNPNFQNPTGTMLHPNRRKKLLSLCADLRIAIVEDDPSSLLTLEKKQPCPTLKSIDENGTVIYV
HSLSKMIAPGLRVGWLVAPQSVVERLSDARHQMELGMSIFPQWLMQQFFETVPFQSHIVPLRKQLTEKRDVIVRALNEQL
HDKISFSNPTGGIYIWGKLKEPINEKQLIMQSLKQEIAFMPGSIFGAKDGYIRLSYGKVNIDQIEEGISRLREAILVCEK

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=315, Percent_Identity=28.2539682539683, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI33469970, Length=315, Percent_Identity=28.2539682539683, Blast_Score=136, Evalue=4e-32,
Organism=Escherichia coli, GI1787710, Length=448, Percent_Identity=25.2232142857143, Blast_Score=152, Evalue=7e-38,
Organism=Escherichia coli, GI1790797, Length=485, Percent_Identity=27.8350515463918, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1788722, Length=390, Percent_Identity=23.5897435897436, Blast_Score=72, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6321236, Length=401, Percent_Identity=21.9451371571072, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21356535, Length=388, Percent_Identity=22.680412371134, Blast_Score=104, Evalue=1e-22,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 54546; Mature: 54546

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWKLDSDSKIPIYQQVVDFIEKRITYGELPPGSFLPSERKLATQLNVNRSTVTTAYNEL
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHH
RAMGIVESTTGKGTRVSTHMWGVSPTLTPNWRNFVEGGTFLPNLPLLRHIRAEVQQNENI
HHHCEEECCCCCCCEEEEEEECCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHCCCCE
IDFANGELGCNLYPHDQLQTILREQPLTHSLSYDHPQGYLPLRQAVVKYMKEYLKVEATE
EEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEECCC
QSIMITSGAQQALHLIVQCLLNPGDAVAFESPSHCYSLPLFQSAGIRIFPLPVDEHGINP
CEEEEECCHHHHHHHHHHHHCCCCCEEEECCCCCEEECCCCCCCCCEEEECCCCCCCCCH
DDVQELYRKHRIKMIFLNPNFQNPTGTMLHPNRRKKLLSLCADLRIAIVEDDPSSLLTLE
HHHHHHHHHCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCHHEEEC
KKQPCPTLKSIDENGTVIYVHSLSKMIAPGLRVGWLVAPQSVVERLSDARHQMELGMSIF
CCCCCCHHHCCCCCCCEEEEECHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHH
PQWLMQQFFETVPFQSHIVPLRKQLTEKRDVIVRALNEQLHDKISFSNPTGGIYIWGKLK
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCC
EPINEKQLIMQSLKQEIAFMPGSIFGAKDGYIRLSYGKVNIDQIEEGISRLREAILVCEK
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEWKLDSDSKIPIYQQVVDFIEKRITYGELPPGSFLPSERKLATQLNVNRSTVTTAYNEL
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHH
RAMGIVESTTGKGTRVSTHMWGVSPTLTPNWRNFVEGGTFLPNLPLLRHIRAEVQQNENI
HHHCEEECCCCCCCEEEEEEECCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHCCCCE
IDFANGELGCNLYPHDQLQTILREQPLTHSLSYDHPQGYLPLRQAVVKYMKEYLKVEATE
EEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEECCC
QSIMITSGAQQALHLIVQCLLNPGDAVAFESPSHCYSLPLFQSAGIRIFPLPVDEHGINP
CEEEEECCHHHHHHHHHHHHCCCCCEEEECCCCCEEECCCCCCCCCEEEECCCCCCCCCH
DDVQELYRKHRIKMIFLNPNFQNPTGTMLHPNRRKKLLSLCADLRIAIVEDDPSSLLTLE
HHHHHHHHHCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCHHEEEC
KKQPCPTLKSIDENGTVIYVHSLSKMIAPGLRVGWLVAPQSVVERLSDARHQMELGMSIF
CCCCCCHHHCCCCCCCEEEEECHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHH
PQWLMQQFFETVPFQSHIVPLRKQLTEKRDVIVRALNEQLHDKISFSNPTGGIYIWGKLK
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCC
EPINEKQLIMQSLKQEIAFMPGSIFGAKDGYIRLSYGKVNIDQIEEGISRLREAILVCEK
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]