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The map label for this gene is dapL [H]

Identifier: 49185706

GI number: 49185706

Start: 2680749

End: 2681951

Strand: Direct

Name: dapL [H]

Synonym: BAS2700

Alternate gene names: 49185706

Gene position: 2680749-2681951 (Clockwise)

Preceding gene: 49185705

Following gene: 49185707

Centisome position: 51.27

GC content: 37.07

Gene sequence:

>1203_bases
TTGATGACTTACACGTTAGCAACTAGAATGAAAGCATTCCAATCTTCTATATTTAGTGAATTAGGGGCCTATAAAAAAGA
AAAAATTGCAGCAGGTCACAAAATGATTGATTTAAGTATCGGGAATCCTGATATGCCACCTGCTGATTTCGTAAGAGAAG
AAATGGTACATACAGCAAATCAAAAAGAAAGCTATGGATACACATTAAGTGGTATTCAAGAATTTCACGAAGCTGTAACT
GAATATTACAACAACACTCATAATGTTATATTAAATGCCGATAAAGAAGTTTTATTATTAATGGGGTCACAAGATGGACT
CGTTCATTTACCTATGGTTTATGCGAATCCGGGAGATATTATATTAGTTCCTGACCCAGGATATACAGCTTATGAAACAG
AAATTCAAATGGCCGGTGCAACATCTTACTATATGCCTTTAAAAAAAGAAAATGATTTCTTACCTAACTTAGAGCTAATT
CCTGAAGAAATTGCGGATCAAGCGAAGATGATGATTTTAAACTTCCCAGGGAATCCCGTTCCAGCAATGGCTCATGAAGA
TTTCTTTAAAGAGGTAATCGCATTCGCGAAAAAGCATAACATTATTGTTGTCCATGATTTTGCTTATGCTGAATTTTATT
TTGATGGTAATAAACCAATTAGCTTCCTCTCTGTGCCTGGTGCGAAAGATGTTGGCGTAGAAATCAACTCTTTGTCAAAA
AGTTATAGTTTAGCAGGTAGCCGTATTGGTTATATGATTGGTAATGAAGAAATTGTCGGGGCACTTACACAATTTAAATC
TAATACGGATTACGGAGTGTTTTTACCAATTCAAAAAGCGGCATGTGCTGCACTAAGAAATGGTGCTGCTTTTTGTGAGA
AAAACCGTGGTATTTATCAAGAACGTAGAGATGCTTTAGTCGATGGGTTCCGAACATTTGGCTGGAATGTTGAAAAACCA
GCTGGCAGTATGTTCGTCTGGGCCGAAATTCCGAAAGGGTGGACTTCTATAGACTTCGCTTATGCATTAATGGATCGTGC
GAATGTCGTTGTCACACCAGGTCATGCATTCGGACCTCACGGAGAAGGGTTTGTACGCATTGCACTCGTTCAAGATAAAG
TAGTGTTACAACAAGTTGTTGAAAACATTAGAAATAGTGGTATTTTCGCCCTTGAAAAAGTAGATGAATTAGTTAAAAAT
TAG

Upstream 100 bases:

>100_bases
TCAATCATTTTAATTTTCATAAAAAAGTGATAAAATGTAACCATGTGTTTTCAGAATAATTAAAAACGTAGAAAGAAAAC
ACTGTTTTTTAGGAGGGGTT

Downstream 100 bases:

>100_bases
TTCCCACTCCCCTGCTTAACTTTAGCAGGGGTATTATTCATTGGAGGTACTTTCATATGCATATTAAAGACACGCTTCCC
CATCGTTATCCATTTTTAAT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MMTYTLATRMKAFQSSIFSELGAYKKEKIAAGHKMIDLSIGNPDMPPADFVREEMVHTANQKESYGYTLSGIQEFHEAVT
EYYNNTHNVILNADKEVLLLMGSQDGLVHLPMVYANPGDIILVPDPGYTAYETEIQMAGATSYYMPLKKENDFLPNLELI
PEEIADQAKMMILNFPGNPVPAMAHEDFFKEVIAFAKKHNIIVVHDFAYAEFYFDGNKPISFLSVPGAKDVGVEINSLSK
SYSLAGSRIGYMIGNEEIVGALTQFKSNTDYGVFLPIQKAACAALRNGAAFCEKNRGIYQERRDALVDGFRTFGWNVEKP
AGSMFVWAEIPKGWTSIDFAYALMDRANVVVTPGHAFGPHGEGFVRIALVQDKVVLQQVVENIRNSGIFALEKVDELVKN

Sequences:

>Translated_400_residues
MMTYTLATRMKAFQSSIFSELGAYKKEKIAAGHKMIDLSIGNPDMPPADFVREEMVHTANQKESYGYTLSGIQEFHEAVT
EYYNNTHNVILNADKEVLLLMGSQDGLVHLPMVYANPGDIILVPDPGYTAYETEIQMAGATSYYMPLKKENDFLPNLELI
PEEIADQAKMMILNFPGNPVPAMAHEDFFKEVIAFAKKHNIIVVHDFAYAEFYFDGNKPISFLSVPGAKDVGVEINSLSK
SYSLAGSRIGYMIGNEEIVGALTQFKSNTDYGVFLPIQKAACAALRNGAAFCEKNRGIYQERRDALVDGFRTFGWNVEKP
AGSMFVWAEIPKGWTSIDFAYALMDRANVVVTPGHAFGPHGEGFVRIALVQDKVVLQQVVENIRNSGIFALEKVDELVKN
>Mature_400_residues
MMTYTLATRMKAFQSSIFSELGAYKKEKIAAGHKMIDLSIGNPDMPPADFVREEMVHTANQKESYGYTLSGIQEFHEAVT
EYYNNTHNVILNADKEVLLLMGSQDGLVHLPMVYANPGDIILVPDPGYTAYETEIQMAGATSYYMPLKKENDFLPNLELI
PEEIADQAKMMILNFPGNPVPAMAHEDFFKEVIAFAKKHNIIVVHDFAYAEFYFDGNKPISFLSVPGAKDVGVEINSLSK
SYSLAGSRIGYMIGNEEIVGALTQFKSNTDYGVFLPIQKAACAALRNGAAFCEKNRGIYQERRDALVDGFRTFGWNVEKP
AGSMFVWAEIPKGWTSIDFAYALMDRANVVVTPGHAFGPHGEGFVRIALVQDKVVLQQVVENIRNSGIFALEKVDELVKN

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=346, Percent_Identity=23.9884393063584, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI56713254, Length=346, Percent_Identity=23.9884393063584, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI95147551, Length=398, Percent_Identity=23.6180904522613, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI169881279, Length=398, Percent_Identity=23.6180904522613, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI169881281, Length=395, Percent_Identity=22.5316455696203, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI4507369, Length=382, Percent_Identity=23.5602094240838, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1788722, Length=385, Percent_Identity=38.1818181818182, Blast_Score=284, Evalue=9e-78,
Organism=Escherichia coli, GI1786816, Length=382, Percent_Identity=21.2041884816754, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788627, Length=312, Percent_Identity=24.0384615384615, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17567369, Length=348, Percent_Identity=25.8620689655172, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI71994476, Length=290, Percent_Identity=25.1724137931034, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71994472, Length=290, Percent_Identity=25.1724137931034, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17567663, Length=371, Percent_Identity=25.8760107816712, Blast_Score=93, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6322401, Length=389, Percent_Identity=23.3933161953728, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28573069, Length=416, Percent_Identity=21.6346153846154, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24646114, Length=416, Percent_Identity=21.6346153846154, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI28573067, Length=416, Percent_Identity=21.6346153846154, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI28573065, Length=416, Percent_Identity=21.6346153846154, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI18859735, Length=224, Percent_Identity=25.8928571428571, Blast_Score=79, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 44472; Mature: 44472

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTYTLATRMKAFQSSIFSELGAYKKEKIAAGHKMIDLSIGNPDMPPADFVREEMVHTAN
CCEEHHHHHHHHHHHHHHHHHCCHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCC
QKESYGYTLSGIQEFHEAVTEYYNNTHNVILNADKEVLLLMGSQDGLVHLPMVYANPGDI
CCCCCCEEHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCEEEEEEEEECCCCE
ILVPDPGYTAYETEIQMAGATSYYMPLKKENDFLPNLELIPEEIADQAKMMILNFPGNPV
EEECCCCCCEEEEEEEEECCCEEEEECCCCCCCCCCHHCCCHHHCCCEEEEEEECCCCCC
PAMAHEDFFKEVIAFAKKHNIIVVHDFAYAEFYFDGNKPISFLSVPGAKDVGVEINSLSK
CCCHHHHHHHHHHHHHHCCCEEEEEECEEEEEEECCCCCEEEEECCCCCCCCEEHHHCCC
SYSLAGSRIGYMIGNEEIVGALTQFKSNTDYGVFLPIQKAACAALRNGAAFCEKNRGIYQ
HHHCCCCEEEEEECCHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHCCHHHHHCCCCHHH
ERRDALVDGFRTFGWNVEKPAGSMFVWAEIPKGWTSIDFAYALMDRANVVVTPGHAFGPH
HHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCCC
GEGFVRIALVQDKVVLQQVVENIRNSGIFALEKVDELVKN
CCCEEEEEEEHHHHHHHHHHHHHHCCCEEEHHHHHHHHCC
>Mature Secondary Structure
MMTYTLATRMKAFQSSIFSELGAYKKEKIAAGHKMIDLSIGNPDMPPADFVREEMVHTAN
CCEEHHHHHHHHHHHHHHHHHCCHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCC
QKESYGYTLSGIQEFHEAVTEYYNNTHNVILNADKEVLLLMGSQDGLVHLPMVYANPGDI
CCCCCCEEHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCEEEEEEEEECCCCE
ILVPDPGYTAYETEIQMAGATSYYMPLKKENDFLPNLELIPEEIADQAKMMILNFPGNPV
EEECCCCCCEEEEEEEEECCCEEEEECCCCCCCCCCHHCCCHHHCCCEEEEEEECCCCCC
PAMAHEDFFKEVIAFAKKHNIIVVHDFAYAEFYFDGNKPISFLSVPGAKDVGVEINSLSK
CCCHHHHHHHHHHHHHHCCCEEEEEECEEEEEEECCCCCEEEEECCCCCCCCEEHHHCCC
SYSLAGSRIGYMIGNEEIVGALTQFKSNTDYGVFLPIQKAACAALRNGAAFCEKNRGIYQ
HHHCCCCEEEEEECCHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHCCHHHHHCCCCHHH
ERRDALVDGFRTFGWNVEKPAGSMFVWAEIPKGWTSIDFAYALMDRANVVVTPGHAFGPH
HHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCCC
GEGFVRIALVQDKVVLQQVVENIRNSGIFALEKVDELVKN
CCCEEEEEEEHHHHHHHHHHHHHHCCCEEEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA