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The map label for this gene is lip2 [H]

Identifier: 49185545

GI number: 49185545

Start: 2530061

End: 2530579

Strand: Direct

Name: lip2 [H]

Synonym: BAS2537

Alternate gene names: 49185545

Gene position: 2530061-2530579 (Clockwise)

Preceding gene: 49185544

Following gene: 49185546

Centisome position: 48.39

GC content: 36.42

Gene sequence:

>519_bases
TTGTGGTGTTCTTTCACAATTAAACTACTTAGAATACACTTCATTTATTTGAAAACAATTACAAATAGAGGTGCTAAAAT
GAAAACTAGAGTAAATCCAGAATTATTACAAGGGTTAGAGATGTTTCCGGATCTCGATTTACGCCCAGGAAATTTGCAAT
CAATCAGAGAAGGAATAGCTCAAATGAGACCACCTACCGTTGTTGATGACTCCCTTTCTTTAATAGATAAAGTCATTGTT
GGGCCTGATGATAATCCGTTACCATTACGAATTTATCGTCCAAAATCAAATCATGAATCTTTACCTGTCTTATTATGGAT
ACATGGTGGAGGTTATATCTTAGGGTCTATAGATGATAACGATGATACTTGTATGAGGTTTGCAAAAGAAGCTAGCTGTG
TGGTCGTGTCTGTAGACTACCGCTTAGCACCTGAACACCCTTACCCAGCACCAATTGAGGATTGTTATTCAGCTTTAAAA
TGGATTGCTGATAATGCATGCAAAGTCATTAAACATTGA

Upstream 100 bases:

>100_bases
CACTACTTGTATTATTGATTGCATGAAACTCCTTCTTGAGAAAGGTTTTAATTTCCGAATATTCTGTTGACTGTTATAAC
ATATCCAATTTACAATTTAA

Downstream 100 bases:

>100_bases
TTCGAATCGAATTGGGGTTGCAGGAGTAAGCGCTGGCGGTGGACTAACAGCAGCATTATCATTATTAGCACGAGATCGAA
AATATCCTTCAATTTGTTTA

Product: carboxylesterase

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MWCSFTIKLLRIHFIYLKTITNRGAKMKTRVNPELLQGLEMFPDLDLRPGNLQSIREGIAQMRPPTVVDDSLSLIDKVIV
GPDDNPLPLRIYRPKSNHESLPVLLWIHGGGYILGSIDDNDDTCMRFAKEASCVVVSVDYRLAPEHPYPAPIEDCYSALK
WIADNACKVIKH

Sequences:

>Translated_172_residues
MWCSFTIKLLRIHFIYLKTITNRGAKMKTRVNPELLQGLEMFPDLDLRPGNLQSIREGIAQMRPPTVVDDSLSLIDKVIV
GPDDNPLPLRIYRPKSNHESLPVLLWIHGGGYILGSIDDNDDTCMRFAKEASCVVVSVDYRLAPEHPYPAPIEDCYSALK
WIADNACKVIKH
>Mature_172_residues
MWCSFTIKLLRIHFIYLKTITNRGAKMKTRVNPELLQGLEMFPDLDLRPGNLQSIREGIAQMRPPTVVDDSLSLIDKVIV
GPDDNPLPLRIYRPKSNHESLPVLLWIHGGGYILGSIDDNDDTCMRFAKEASCVVVSVDYRLAPEHPYPAPIEDCYSALK
WIADNACKVIKH

Specific function: Has An Esterase Activity. Triacetyl Glycerol (Triacetin) Is A Substrate Of The Enzyme. [C]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Homo sapiens, GI157041239, Length=84, Percent_Identity=34.5238095238095, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17540028, Length=81, Percent_Identity=39.5061728395062, Blast_Score=70, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI72001146, Length=104, Percent_Identity=32.6923076923077, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094
- InterPro:   IPR002168 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 19472; Mature: 19472

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWCSFTIKLLRIHFIYLKTITNRGAKMKTRVNPELLQGLEMFPDLDLRPGNLQSIREGIA
CCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHCCCCCCCCCCHHHHHHHHH
QMRPPTVVDDSLSLIDKVIVGPDDNPLPLRIYRPKSNHESLPVLLWIHGGGYILGSIDDN
HCCCCCEECHHHHHHHHHEECCCCCCCCEEEECCCCCCCCCCEEEEEECCCEEEEECCCC
DDTCMRFAKEASCVVVSVDYRLAPEHPYPAPIEDCYSALKWIADNACKVIKH
HHHHHHHHHCCCEEEEEECCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MWCSFTIKLLRIHFIYLKTITNRGAKMKTRVNPELLQGLEMFPDLDLRPGNLQSIREGIA
CCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHCCCCCCCCCCHHHHHHHHH
QMRPPTVVDDSLSLIDKVIVGPDDNPLPLRIYRPKSNHESLPVLLWIHGGGYILGSIDDN
HCCCCCEECHHHHHHHHHEECCCCCCCCEEEECCCCCCCCCCEEEEEECCCEEEEECCCC
DDTCMRFAKEASCVVVSVDYRLAPEHPYPAPIEDCYSALKWIADNACKVIKH
HHHHHHHHHCCCEEEEEECCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1907455 [H]