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The map label for this gene is licC [H]

Identifier: 49185300

GI number: 49185300

Start: 2291082

End: 2292368

Strand: Direct

Name: licC [H]

Synonym: BAS2291

Alternate gene names: 49185300

Gene position: 2291082-2292368 (Clockwise)

Preceding gene: 49185299

Following gene: 49185301

Centisome position: 43.82

GC content: 35.98

Gene sequence:

>1287_bases
ATGAATAAGTTTGTCACGTTTCTTGATAAAAACTTATCTGGACCGATGGCAAGACTTTCTGAACAGAGACATTTACAAGC
AATCCGTGATGGAGTTATTTCAGCATTACCATTTATCATCGTAGGAAGTTTCTTTTTAATCGTAGCATTTCCACCATTAC
CGAAAGATAGTTTCATATCCGTTTGGGCATTAAAGAATCAAACAAGTATATTAATACCATATCGCCTAACGATGTTTATT
ATGTCTTTATATATAGCATTTGGAATAGGATATAATTTAGCGAAGAGTTATAAGTTAGATGCTTTATCGGGAGCTCAGCT
TGCAGTATGTTCACTGCTATTAACATTAACTCCTGAATTAATTGATAAAAAAGGATTTATGCTTCCGATGACAAATCTCG
GAGGGCATGGATTATTCGTGACTATGATTGTTTCTATTTTATCAGTTGAGATTTTAAGATTTTGTAAGAAGAACAACGTA
ACGATCAAAATGCCAGAACAAGTACCACCTTCAGTATCGCGTTCGTTTGAAGCACTTATACCTGCTGCATTCGTTATTAT
TATTATTATGAGCCTTATTACAGTTGTTTTTAAAGTTGATGTACATTACGTAGTGGATAAATTAGCCGCACCGTTAGTCA
AAGCTGGAGATAGTTACTTTGGCGTCATAATACCTGTATTTTTAATTACATTTTTCTGGTCCTTCGGAATACATGGTGTA
TCGGTTGTAGGTACTGTAGCAAGACCGCTTTGGGATGTATATTTAGGGAAAAATGGTGAAGCTGTAGCAAGTGGTGCGAG
TCAATTTCCATTCATTGCACCAGAACCGTTTTATCAATGGTTTATTTGGATTGGTGGTTCGGGTGCAACGTTAGGGCTTG
TGTTAGCAATGATCGTATTTGGTCGATCAAAATATTCGAAGGCATTATCGAGAACTTGTATTGTGCCTGGGATTTTTAAT
ATTAATGAACCAGTTATATTCGGCTTGCCGATTGTATTGAATCCAATTTTAATTATTCCTTTCGTCATTACGCCGCTAGT
AACAGCGACTATCGCTTATGCTGCAACTGCAATGGGATTTGTAACGCCAACTCATATTATGCCGCCATGGACATTACCAG
CCCCAATTGGTGCATATTTAGCTACAGGAGGAGATTGGCGTGCAATTGTATTAGTCTTAATAAATATAGCAATATCATTC
CTTATTTATTTACCATTCTTTAAAATGTACGACAAAAATATGCTTGAAATTGAGAAGAATGGTGAAGGAGAATCTGTTAA
TCCATAA

Upstream 100 bases:

>100_bases
CTATTCCGTGTGGTATCATTCCGCCGCAAGCATATACGCCACTTGGCGGACCGACTTTATTAAAGACTGTAAATGATTTA
ATTCGTTAGGGGGAACCGTT

Downstream 100 bases:

>100_bases
TCTTTATGCTTTATTTTGTGAGTGATAGGCATTTTGTCTATCACTTCTTTCACATTAAGTTGAGAGAGGGTGAAATGGAA
TGAATATAAAATTTAGTTAT

Product: PTS system cellobiose-specific transporter subunit IIC

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Lic; PTS system lichenan-specific EIIC component [H]

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MNKFVTFLDKNLSGPMARLSEQRHLQAIRDGVISALPFIIVGSFFLIVAFPPLPKDSFISVWALKNQTSILIPYRLTMFI
MSLYIAFGIGYNLAKSYKLDALSGAQLAVCSLLLTLTPELIDKKGFMLPMTNLGGHGLFVTMIVSILSVEILRFCKKNNV
TIKMPEQVPPSVSRSFEALIPAAFVIIIIMSLITVVFKVDVHYVVDKLAAPLVKAGDSYFGVIIPVFLITFFWSFGIHGV
SVVGTVARPLWDVYLGKNGEAVASGASQFPFIAPEPFYQWFIWIGGSGATLGLVLAMIVFGRSKYSKALSRTCIVPGIFN
INEPVIFGLPIVLNPILIIPFVITPLVTATIAYAATAMGFVTPTHIMPPWTLPAPIGAYLATGGDWRAIVLVLINIAISF
LIYLPFFKMYDKNMLEIEKNGEGESVNP

Sequences:

>Translated_428_residues
MNKFVTFLDKNLSGPMARLSEQRHLQAIRDGVISALPFIIVGSFFLIVAFPPLPKDSFISVWALKNQTSILIPYRLTMFI
MSLYIAFGIGYNLAKSYKLDALSGAQLAVCSLLLTLTPELIDKKGFMLPMTNLGGHGLFVTMIVSILSVEILRFCKKNNV
TIKMPEQVPPSVSRSFEALIPAAFVIIIIMSLITVVFKVDVHYVVDKLAAPLVKAGDSYFGVIIPVFLITFFWSFGIHGV
SVVGTVARPLWDVYLGKNGEAVASGASQFPFIAPEPFYQWFIWIGGSGATLGLVLAMIVFGRSKYSKALSRTCIVPGIFN
INEPVIFGLPIVLNPILIIPFVITPLVTATIAYAATAMGFVTPTHIMPPWTLPAPIGAYLATGGDWRAIVLVLINIAISF
LIYLPFFKMYDKNMLEIEKNGEGESVNP
>Mature_428_residues
MNKFVTFLDKNLSGPMARLSEQRHLQAIRDGVISALPFIIVGSFFLIVAFPPLPKDSFISVWALKNQTSILIPYRLTMFI
MSLYIAFGIGYNLAKSYKLDALSGAQLAVCSLLLTLTPELIDKKGFMLPMTNLGGHGLFVTMIVSILSVEILRFCKKNNV
TIKMPEQVPPSVSRSFEALIPAAFVIIIIMSLITVVFKVDVHYVVDKLAAPLVKAGDSYFGVIIPVFLITFFWSFGIHGV
SVVGTVARPLWDVYLGKNGEAVASGASQFPFIAPEPFYQWFIWIGGSGATLGLVLAMIVFGRSKYSKALSRTCIVPGIFN
INEPVIFGLPIVLNPILIIPFVITPLVTATIAYAATAMGFVTPTHIMPPWTLPAPIGAYLATGGDWRAIVLVLINIAISF
LIYLPFFKMYDKNMLEIEKNGEGESVNP

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=451, Percent_Identity=31.7073170731707, Blast_Score=207, Evalue=2e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 46908; Mature: 46908

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCC
>Mature Secondary Structure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CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]