| Definition | Bacillus anthracis str. Sterne chromosome, complete genome. |
|---|---|
| Accession | NC_005945 |
| Length | 5,228,663 |
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The map label for this gene is ponA [H]
Identifier: 49185194
GI number: 49185194
Start: 2177459
End: 2179999
Strand: Direct
Name: ponA [H]
Synonym: BAS2185
Alternate gene names: 49185194
Gene position: 2177459-2179999 (Clockwise)
Preceding gene: 49185193
Following gene: 49185195
Centisome position: 41.64
GC content: 37.15
Gene sequence:
>2541_bases ATGTCAGAAAATTATCGTTCTCGAGAGGAGCGACGACAAGTTAAAAAGAAAAAACAGCCAGCTTCTAAAACACAAAAACC AAAAGGTAAAACATCGTTCTTTCGCAAGTTTTTAATTACTTGTTTATTACTTGGTATTGTTGGTTTAGTGGGGGGAGTTG CTACCTTTTTCGTAATGATTAAGGATGCACCAAAACTTGAGAAAGCAAAACTTGTTAATCCGTTATCCTCAAAAATTTAT GATAAAAATGGCGATTTGGTATATGAATACGGGAAAGAAAAACGGACGAATGTTACGTATGATCAAATTCCTAAATTAGT AGAAAATGCATTTTTAGCAACAGAAGATGCACGTTTTTACGAGCATAGCGGAGTAGACTTTAAAGGTACTGCCCGTGCTG TTTTGGTGAGTCTTAAAGGCGATTACGGTTCACAAGGTGGAAGTACGATAACACAGCAGGTTATTAAAAATTACTTCTTA TCGATGGAAAAAACATCAAAACGTAAGATTCAAGAAATATATTTAGCGTATAAGCTAGAACAACAGTATTCAAAACATGA AATTTTAGAAATGTATTTAAATAAAATTAATTTAGGTAATCGTTCATATGGTATCGCAACAGCAGCACAAAACTACTACG GTAAAGAATTAAAAGAGTTAACTTTACCAGAAGTTGCGATGCTTGCAGGTTTACCAAAAGCACCGAATAACTATGATCCA ACGAAGACAGAAAATGTTCAAAGAGCAACAGAAAGAAGAAATGTTGTCCTAAAATTAATGAATCGACATGGTTATATTAC GAAGGCAGAAATGGAAGAAGCTTCGAAAGTTGAAGTAACAGATGGACTTAAGACTGCAACTGTACAAGCAATGCCATATC CTGCATTTATGGATGCGGTTGTGAAAGAAGTTGAAAAAGAATTGCCAGATGCTAATATTGGTTCTGACGGTTTAGAAATT TATACAACATTAGACATAGACGCACAGAAGGCTGCCGACAGGATATTAGATGCTAATATTATTAATTATCCAAATGATAA ATTCCAAAGTGCTTTCACATTTATGGATACGAAAACAGGAGAAGTTCGTGCTATAGGTAGTGGACGTGGTGAAAATAAAG CAGTATTTAAAGGGCATAATATGGCAATTGAATTAGATCGTGCAGCTGGTTCAACTATGAAGCCAATCTTTGATTACGGT CCTGCAATTGAATACTTAAAATGGGCTACGTATCATCAAATTGATGATTCTCCATTTAAATATTCAACTGGACAAGAAGT TCGAAATGCGGACAGAAGTCATTTAGGATCAATTACGATGCGTGAAGCATTAAAAATGTCACGTAACGTTCCGGCAGTTA AAGCTGCAAAAGAAGTAGGACTTAATAAAGCGAAGGAATTCTCTGAGAAATTAGGTATTACACTTAAGTCAGCACCAGAA TCTACAGCGATTGGTACAAACGAAGTATCACCAACTGAAATAGCGGGTGCTTATGCGACATTTGGTAATGGTGGAAAGTA TGCAAAACCGCATTTTGTTAAGAAAGTAGTTTATCCAGACGGCAAGTCACAAAGTTTTGGACAAAAACCAAAACAAGTTA TAGCTGACTCTACAGCATATATGATTACTGATATGCTTCGTTCAGTAGTGACATCAGGTACTGGTACAGCAGCAAATATA AGTTCTTTAGATGTAGCTGGAAAAACAGGTACAACAAACTATGATTCAAAACAATTAGCGAAATTTAATATTCCGGAAAG TGCAACTCGTGATAGTTGGTTTGCAGGTTATACGCCGCAATATACGATGGCAGTATGGACTGGGTATATGAAAGATGGTA AGGACGAGTATATTAGTAGTAAAAATACGAAAATTGCACAGTTGATCTTTAAAGAAATGATGAGCGAGATGGCTACAGAT AAATCAAGATTTAAAATGCCAAGTAGTGTAATTCAAGAAGGTAGTGAGCTGCGTATAAAAGGTGAAAAACGTGATTCTTC TCCAAATACGAGCGTACCGGATACAACAGAAAAACCAAAACAAGATCAACAGCAAAAAACTGAAGAAGAGAAAAAGCAAG AAGAATTAAAAAAACAAGAAGAACTTAAAAAACAAGAAGAAGAAAAGAAACAAGAGGAACTGAAGAAGCAGGAAGAACAA AAGAAACTAGAAGAGCAAAAGAAACAAGAAGAAGAAAAGAAACAAAATGAACAAAATAATGGAAACGGTCAAGGAACGAC CCCTCCAGCAAATAACGGAGGAGGTCAAGGAACGACCCCTCCAGCAAATAACGGAGGAGGTCAAGGAAATACGACTCCTC CAGCAAATAACGGAGGAGGTCAAGGAAATACAACCCCTCCAGCAAATAACGGAGGAGGTCAAGGAAATACAACCCCTCCA GCAAATAATGGAGGAGGTCAAGGAAATACAACCCCTCCAGCAAATAATGGAGGAGGTCAAGGAAATACAACTCCACCAGC GACCACACAACCGGAGACTGGCGGTAATGCAGGAGAGGCCCCTGCTAATAATGGTCAATAA
Upstream 100 bases:
>100_bases CTCCAGGTCGATATACTTTCTTAATTTAATTCATTTTAGAAAGTGACCTCAATATTTTTAAGTAAATCAACGGGAGAATT GAAAGGCAGGAGAAAGTAAC
Downstream 100 bases:
>100_bases GAAAATTTTATAAAAAATATTAAAAAGCACTTAAGATTTGTAAAAATTACAATCTTAAGTGCTTTTTTCGTTAAATGTAG TAGCTATGAGACGATGTATT
Product: penicillin-binding protein 1A
Products: NA
Alternate protein names: PBP1; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 846; Mature: 845
Protein sequence:
>846_residues MSENYRSREERRQVKKKKQPASKTQKPKGKTSFFRKFLITCLLLGIVGLVGGVATFFVMIKDAPKLEKAKLVNPLSSKIY DKNGDLVYEYGKEKRTNVTYDQIPKLVENAFLATEDARFYEHSGVDFKGTARAVLVSLKGDYGSQGGSTITQQVIKNYFL SMEKTSKRKIQEIYLAYKLEQQYSKHEILEMYLNKINLGNRSYGIATAAQNYYGKELKELTLPEVAMLAGLPKAPNNYDP TKTENVQRATERRNVVLKLMNRHGYITKAEMEEASKVEVTDGLKTATVQAMPYPAFMDAVVKEVEKELPDANIGSDGLEI YTTLDIDAQKAADRILDANIINYPNDKFQSAFTFMDTKTGEVRAIGSGRGENKAVFKGHNMAIELDRAAGSTMKPIFDYG PAIEYLKWATYHQIDDSPFKYSTGQEVRNADRSHLGSITMREALKMSRNVPAVKAAKEVGLNKAKEFSEKLGITLKSAPE STAIGTNEVSPTEIAGAYATFGNGGKYAKPHFVKKVVYPDGKSQSFGQKPKQVIADSTAYMITDMLRSVVTSGTGTAANI SSLDVAGKTGTTNYDSKQLAKFNIPESATRDSWFAGYTPQYTMAVWTGYMKDGKDEYISSKNTKIAQLIFKEMMSEMATD KSRFKMPSSVIQEGSELRIKGEKRDSSPNTSVPDTTEKPKQDQQQKTEEEKKQEELKKQEELKKQEEEKKQEELKKQEEQ KKLEEQKKQEEEKKQNEQNNGNGQGTTPPANNGGGQGTTPPANNGGGQGNTTPPANNGGGQGNTTPPANNGGGQGNTTPP ANNGGGQGNTTPPANNGGGQGNTTPPATTQPETGGNAGEAPANNGQ
Sequences:
>Translated_846_residues MSENYRSREERRQVKKKKQPASKTQKPKGKTSFFRKFLITCLLLGIVGLVGGVATFFVMIKDAPKLEKAKLVNPLSSKIY DKNGDLVYEYGKEKRTNVTYDQIPKLVENAFLATEDARFYEHSGVDFKGTARAVLVSLKGDYGSQGGSTITQQVIKNYFL SMEKTSKRKIQEIYLAYKLEQQYSKHEILEMYLNKINLGNRSYGIATAAQNYYGKELKELTLPEVAMLAGLPKAPNNYDP TKTENVQRATERRNVVLKLMNRHGYITKAEMEEASKVEVTDGLKTATVQAMPYPAFMDAVVKEVEKELPDANIGSDGLEI YTTLDIDAQKAADRILDANIINYPNDKFQSAFTFMDTKTGEVRAIGSGRGENKAVFKGHNMAIELDRAAGSTMKPIFDYG PAIEYLKWATYHQIDDSPFKYSTGQEVRNADRSHLGSITMREALKMSRNVPAVKAAKEVGLNKAKEFSEKLGITLKSAPE STAIGTNEVSPTEIAGAYATFGNGGKYAKPHFVKKVVYPDGKSQSFGQKPKQVIADSTAYMITDMLRSVVTSGTGTAANI SSLDVAGKTGTTNYDSKQLAKFNIPESATRDSWFAGYTPQYTMAVWTGYMKDGKDEYISSKNTKIAQLIFKEMMSEMATD KSRFKMPSSVIQEGSELRIKGEKRDSSPNTSVPDTTEKPKQDQQQKTEEEKKQEELKKQEELKKQEEEKKQEELKKQEEQ KKLEEQKKQEEEKKQNEQNNGNGQGTTPPANNGGGQGTTPPANNGGGQGNTTPPANNGGGQGNTTPPANNGGGQGNTTPP ANNGGGQGNTTPPANNGGGQGNTTPPATTQPETGGNAGEAPANNGQ >Mature_845_residues SENYRSREERRQVKKKKQPASKTQKPKGKTSFFRKFLITCLLLGIVGLVGGVATFFVMIKDAPKLEKAKLVNPLSSKIYD KNGDLVYEYGKEKRTNVTYDQIPKLVENAFLATEDARFYEHSGVDFKGTARAVLVSLKGDYGSQGGSTITQQVIKNYFLS MEKTSKRKIQEIYLAYKLEQQYSKHEILEMYLNKINLGNRSYGIATAAQNYYGKELKELTLPEVAMLAGLPKAPNNYDPT KTENVQRATERRNVVLKLMNRHGYITKAEMEEASKVEVTDGLKTATVQAMPYPAFMDAVVKEVEKELPDANIGSDGLEIY TTLDIDAQKAADRILDANIINYPNDKFQSAFTFMDTKTGEVRAIGSGRGENKAVFKGHNMAIELDRAAGSTMKPIFDYGP AIEYLKWATYHQIDDSPFKYSTGQEVRNADRSHLGSITMREALKMSRNVPAVKAAKEVGLNKAKEFSEKLGITLKSAPES TAIGTNEVSPTEIAGAYATFGNGGKYAKPHFVKKVVYPDGKSQSFGQKPKQVIADSTAYMITDMLRSVVTSGTGTAANIS SLDVAGKTGTTNYDSKQLAKFNIPESATRDSWFAGYTPQYTMAVWTGYMKDGKDEYISSKNTKIAQLIFKEMMSEMATDK SRFKMPSSVIQEGSELRIKGEKRDSSPNTSVPDTTEKPKQDQQQKTEEEKKQEELKKQEELKKQEEEKKQEELKKQEEQK KLEEQKKQEEEKKQNEQNNGNGQGTTPPANNGGGQGTTPPANNGGGQGNTTPPANNGGGQGNTTPPANNGGGQGNTTPPA NNGGGQGNTTPPANNGGGQGNTTPPATTQPETGGNAGEAPANNGQ
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG0744
COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)
Gene ontology:
Cell location: Cell membrane; Single-pass type II membrane protein. Note=Probably found all over the whole cell at low concentrations. Also localizes to the division site in vegetative cells [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 fibronectin type-III domain [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=314, Percent_Identity=42.0382165605096, Blast_Score=239, Evalue=6e-64, Organism=Escherichia coli, GI1786343, Length=541, Percent_Identity=33.826247689464, Blast_Score=224, Evalue=2e-59, Organism=Escherichia coli, GI1788867, Length=581, Percent_Identity=27.3666092943201, Blast_Score=131, Evalue=2e-31, Organism=Escherichia coli, GI1789601, Length=233, Percent_Identity=31.3304721030043, Blast_Score=91, Evalue=4e-19,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR008957 - InterPro: IPR003961 - InterPro: IPR001264 - InterPro: IPR013783 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00041 fn3; PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.-
Molecular weight: Translated: 92743; Mature: 92612
Theoretical pI: Translated: 9.51; Mature: 9.51
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.1 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 0.1 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 2.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSENYRSREERRQVKKKKQPASKTQKPKGKTSFFRKFLITCLLLGIVGLVGGVATFFVMI CCCCCCCHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH KDAPKLEKAKLVNPLSSKIYDKNGDLVYEYGKEKRTNVTYDQIPKLVENAFLATEDARFY CCCCCHHHHHHHCHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCHHH EHSGVDFKGTARAVLVSLKGDYGSQGGSTITQQVIKNYFLSMEKTSKRKIQEIYLAYKLE HCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH QQYSKHEILEMYLNKINLGNRSYGIATAAQNYYGKELKELTLPEVAMLAGLPKAPNNYDP HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCC TKTENVQRATERRNVVLKLMNRHGYITKAEMEEASKVEVTDGLKTATVQAMPYPAFMDAV CCHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHCCCCEECCCCCCCEEEECCCCHHHHHHH VKEVEKELPDANIGSDGLEIYTTLDIDAQKAADRILDANIINYPNDKFQSAFTFMDTKTG HHHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHHHHHCHHCCCCCHHHHHHHHHHCCCCC EVRAIGSGRGENKAVFKGHNMAIELDRAAGSTMKPIFDYGPAIEYLKWATYHQIDDSPFK CEEEECCCCCCCCEEEECCCEEEEEECCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCC YSTGQEVRNADRSHLGSITMREALKMSRNVPAVKAAKEVGLNKAKEFSEKLGITLKSAPE CCCCHHHHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHCCEEECCCC STAIGTNEVSPTEIAGAYATFGNGGKYAKPHFVKKVVYPDGKSQSFGQKPKQVIADSTAY CCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHEECCCCCCCCCCCCHHHHHHCCHHH MITDMLRSVVTSGTGTAANISSLDVAGKTGTTNYDSKQLAKFNIPESATRDSWFAGYTPQ HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCC YTMAVWTGYMKDGKDEYISSKNTKIAQLIFKEMMSEMATDKSRFKMPSSVIQEGSELRIK HHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHCCCHHHHCCCCCEEEE GEKRDSSPNTSVPDTTEKPKQDQQQKTEEEKKQEELKKQEELKKQEEEKKQEELKKQEEQ CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH KKLEEQKKQEEEKKQNEQNNGNGQGTTPPANNGGGQGTTPPANNGGGQGNTTPPANNGGG HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC QGNTTPPANNGGGQGNTTPPANNGGGQGNTTPPANNGGGQGNTTPPATTQPETGGNAGEA CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC PANNGQ CCCCCC >Mature Secondary Structure SENYRSREERRQVKKKKQPASKTQKPKGKTSFFRKFLITCLLLGIVGLVGGVATFFVMI CCCCCCHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH KDAPKLEKAKLVNPLSSKIYDKNGDLVYEYGKEKRTNVTYDQIPKLVENAFLATEDARFY CCCCCHHHHHHHCHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCHHH EHSGVDFKGTARAVLVSLKGDYGSQGGSTITQQVIKNYFLSMEKTSKRKIQEIYLAYKLE HCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH QQYSKHEILEMYLNKINLGNRSYGIATAAQNYYGKELKELTLPEVAMLAGLPKAPNNYDP HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCC TKTENVQRATERRNVVLKLMNRHGYITKAEMEEASKVEVTDGLKTATVQAMPYPAFMDAV CCHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHCCCCEECCCCCCCEEEECCCCHHHHHHH VKEVEKELPDANIGSDGLEIYTTLDIDAQKAADRILDANIINYPNDKFQSAFTFMDTKTG HHHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHHHHHCHHCCCCCHHHHHHHHHHCCCCC EVRAIGSGRGENKAVFKGHNMAIELDRAAGSTMKPIFDYGPAIEYLKWATYHQIDDSPFK CEEEECCCCCCCCEEEECCCEEEEEECCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCC YSTGQEVRNADRSHLGSITMREALKMSRNVPAVKAAKEVGLNKAKEFSEKLGITLKSAPE CCCCHHHHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHCCEEECCCC STAIGTNEVSPTEIAGAYATFGNGGKYAKPHFVKKVVYPDGKSQSFGQKPKQVIADSTAY CCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHEECCCCCCCCCCCCHHHHHHCCHHH MITDMLRSVVTSGTGTAANISSLDVAGKTGTTNYDSKQLAKFNIPESATRDSWFAGYTPQ HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCC YTMAVWTGYMKDGKDEYISSKNTKIAQLIFKEMMSEMATDKSRFKMPSSVIQEGSELRIK HHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHCCCHHHHCCCCCEEEE GEKRDSSPNTSVPDTTEKPKQDQQQKTEEEKKQEELKKQEELKKQEEEKKQEELKKQEEQ CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH KKLEEQKKQEEEKKQNEQNNGNGQGTTPPANNGGGQGTTPPANNGGGQGNTTPPANNGGG HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC QGNTTPPANNGGGQGNTTPPANNGGGQGNTTPPANNGGGQGNTTPPATTQPETGGNAGEA CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC PANNGQ CCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 7814321; 8760912; 9384377; 9721295; 10322023 [H]