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The map label for this gene is 49184627

Identifier: 49184627

GI number: 49184627

Start: 1631687

End: 1632997

Strand: Direct

Name: 49184627

Synonym: BAS1613

Alternate gene names: NA

Gene position: 1631687-1632997 (Clockwise)

Preceding gene: 49184626

Following gene: 49184628

Centisome position: 31.21

GC content: 35.77

Gene sequence:

>1311_bases
ATGTTTATTACTTCTGCAGCATATGGAGCAAAAACGAAAAGGGGTAGCATGATGAGGGTAGAAGTATGGGGAGGAGCGGG
AGAATACGGTCGTTCCTGCTATTTCGTAAAAAATAAAGAGACAAAAATATTATTTGATTGTGGTATTAATCGATCATATG
AGGATAGTTATCCAAAAATAGAGCGGGAAGTTGTACCGTTTTTAGATGCAGTATTTTTATCACATATTCATGAAGATCAT
ACGATGGGCTTACCTTTATTAGCGAAGTATGGATATAAGAAAAAAATCTGGACAACTCGTTATACGAAGGAGCAACTTCC
CGCTTATTATGAAAAATGGAGAAACTACAATGTGACGCAAGGATGGAATGTGCCATATAACGACCAAAATGTGAAAGATT
TAAATTATATATATGTTGATGAGATTAGTAATCCGAATGAATGGATACAGATTACTCCAACATTGCGGTTTCAATGGGGG
TATAGTGGGCACGTATTAGGATCGGTTTGGTTTTTAGTGGATATGAGTCATACATATGTATTTTATTCTGGCGATTATTC
AGCAGAGTCTAACATACTACGAGCGAATTTACCTGAGAAATTGCGCGGCGATATAAAAGTTGCAATTGTAGATGCCGCTT
ATCATACTGATGATGTTTCGCAACGTGAACGAGTAAACGAACTATGTACAGAAATTGAACGAGCTGCGGGGAATAAAGGG
ATAGCATTACTACCATTGCCACCCCTTGGTAGGGCGCAAGATATCGTATTGTATTTATATGAAAAATATAAAGAATTTCC
CATTATAGTAGATCAGGAAATTTTAGATGGATTTGACGAGATGTTCTTATATAAAGATTGGATCAAAAATAATAAAGAAC
TTGAAGAGCTAATGGAGAGTTTAAAAAGAAACATAATAGTTATGGATGATGACGGCGGTACGCAACATAGTTGTGGAATA
GTTGTAATGAGTGATGCGAATATGCAAACGAAACGGGCTCAGTTATATTATGAACAAATTCGGCATGAAGAAAGAAATTC
TATTATCTTTACTGGGCATGTTGCGAAAGGGAGTTTTGCAGAAAAAGTTTTGAAAGAACGTATAGGTAAAGAATGTAGGG
TGAAGCGAGTTCCATATAAAGTTCATCAAAGTATAAGAGATGTGAAAGAGATGTTAAATACATTATTACCGGAACATACG
GTGTTAGTACACGCTTTAAAAGAGGATACAGATCGATTACAGAAAAAGCTTAGCACGGCAGGGTATGAAAATGTATATTC
ACTTACTATGGAACGTATAGAAGTTATTTAA

Upstream 100 bases:

>100_bases
CAGTAGAGACGTCAGCAACATTTATTTTTGCTCAATTTGAACAAGGAGAAGTATCTATTGGAATGGCGATGGCTGTCGTT
TCAGTTGGACTTACAACGCT

Downstream 100 bases:

>100_bases
CATGTAAAGGGGATAGGTATATGAAAAAAGTATTTGTATTCGTGAGTATTTTCTTTTGTTGTTTCCTTTATTCCGATAAG
GAAGGGTTTGCTGCTAGTCC

Product: metallo-beta-lactamase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MFITSAAYGAKTKRGSMMRVEVWGGAGEYGRSCYFVKNKETKILFDCGINRSYEDSYPKIEREVVPFLDAVFLSHIHEDH
TMGLPLLAKYGYKKKIWTTRYTKEQLPAYYEKWRNYNVTQGWNVPYNDQNVKDLNYIYVDEISNPNEWIQITPTLRFQWG
YSGHVLGSVWFLVDMSHTYVFYSGDYSAESNILRANLPEKLRGDIKVAIVDAAYHTDDVSQRERVNELCTEIERAAGNKG
IALLPLPPLGRAQDIVLYLYEKYKEFPIIVDQEILDGFDEMFLYKDWIKNNKELEELMESLKRNIIVMDDDGGTQHSCGI
VVMSDANMQTKRAQLYYEQIRHEERNSIIFTGHVAKGSFAEKVLKERIGKECRVKRVPYKVHQSIRDVKEMLNTLLPEHT
VLVHALKEDTDRLQKKLSTAGYENVYSLTMERIEVI

Sequences:

>Translated_436_residues
MFITSAAYGAKTKRGSMMRVEVWGGAGEYGRSCYFVKNKETKILFDCGINRSYEDSYPKIEREVVPFLDAVFLSHIHEDH
TMGLPLLAKYGYKKKIWTTRYTKEQLPAYYEKWRNYNVTQGWNVPYNDQNVKDLNYIYVDEISNPNEWIQITPTLRFQWG
YSGHVLGSVWFLVDMSHTYVFYSGDYSAESNILRANLPEKLRGDIKVAIVDAAYHTDDVSQRERVNELCTEIERAAGNKG
IALLPLPPLGRAQDIVLYLYEKYKEFPIIVDQEILDGFDEMFLYKDWIKNNKELEELMESLKRNIIVMDDDGGTQHSCGI
VVMSDANMQTKRAQLYYEQIRHEERNSIIFTGHVAKGSFAEKVLKERIGKECRVKRVPYKVHQSIRDVKEMLNTLLPEHT
VLVHALKEDTDRLQKKLSTAGYENVYSLTMERIEVI
>Mature_436_residues
MFITSAAYGAKTKRGSMMRVEVWGGAGEYGRSCYFVKNKETKILFDCGINRSYEDSYPKIEREVVPFLDAVFLSHIHEDH
TMGLPLLAKYGYKKKIWTTRYTKEQLPAYYEKWRNYNVTQGWNVPYNDQNVKDLNYIYVDEISNPNEWIQITPTLRFQWG
YSGHVLGSVWFLVDMSHTYVFYSGDYSAESNILRANLPEKLRGDIKVAIVDAAYHTDDVSQRERVNELCTEIERAAGNKG
IALLPLPPLGRAQDIVLYLYEKYKEFPIIVDQEILDGFDEMFLYKDWIKNNKELEELMESLKRNIIVMDDDGGTQHSCGI
VVMSDANMQTKRAQLYYEQIRHEERNSIIFTGHVAKGSFAEKVLKERIGKECRVKRVPYKVHQSIRDVKEMLNTLLPEHT
VLVHALKEDTDRLQKKLSTAGYENVYSLTMERIEVI

Specific function: Unknown

COG id: COG1782

COG function: function code R; Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI7706427, Length=440, Percent_Identity=25, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI33300633, Length=439, Percent_Identity=24.1457858769932, Blast_Score=111, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI32566029, Length=434, Percent_Identity=23.0414746543779, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI32564696, Length=438, Percent_Identity=22.3744292237443, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6323307, Length=435, Percent_Identity=22.2988505747126, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24648013, Length=437, Percent_Identity=24.0274599542334, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI21358523, Length=432, Percent_Identity=22.9166666666667, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022712
- InterPro:   IPR001279
- InterPro:   IPR004087
- InterPro:   IPR019975
- InterPro:   IPR004044
- InterPro:   IPR011108 [H]

Pfam domain/function: PF10996 Beta-Casp; PF07650 KH_2; PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 50735; Mature: 50735

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFITSAAYGAKTKRGSMMRVEVWGGAGEYGRSCYFVKNKETKILFDCGINRSYEDSYPKI
CEEECCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCHH
EREVVPFLDAVFLSHIHEDHTMGLPLLAKYGYKKKIWTTRYTKEQLPAYYEKWRNYNVTQ
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCEEEECCCHHHHHHHHHHHCCCCCCC
GWNVPYNDQNVKDLNYIYVDEISNPNEWIQITPTLRFQWGYSGHVLGSVWFLVDMSHTYV
CCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEEEEEECCCCCCHHHEEEEEEEECCEEE
FYSGDYSAESNILRANLPEKLRGDIKVAIVDAAYHTDDVSQRERVNELCTEIERAAGNKG
EEECCCCCCCCEEECCCCHHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCC
IALLPLPPLGRAQDIVLYLYEKYKEFPIIVDQEILDGFDEMFLYKDWIKNNKELEELMES
EEEEECCCCCCHHHHHHHHHHHHCCCCEEECHHHHCCHHHHHHHHHHHCCCHHHHHHHHH
LKRNIIVMDDDGGTQHSCGIVVMSDANMQTKRAQLYYEQIRHEERNSIIFTGHVAKGSFA
HHCCEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHH
EKVLKERIGKECRVKRVPYKVHQSIRDVKEMLNTLLPEHTVLVHALKEDTDRLQKKLSTA
HHHHHHHCCCHHEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
GYENVYSLTMERIEVI
CCHHHHHHHHHHHHCC
>Mature Secondary Structure
MFITSAAYGAKTKRGSMMRVEVWGGAGEYGRSCYFVKNKETKILFDCGINRSYEDSYPKI
CEEECCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCHH
EREVVPFLDAVFLSHIHEDHTMGLPLLAKYGYKKKIWTTRYTKEQLPAYYEKWRNYNVTQ
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCEEEECCCHHHHHHHHHHHCCCCCCC
GWNVPYNDQNVKDLNYIYVDEISNPNEWIQITPTLRFQWGYSGHVLGSVWFLVDMSHTYV
CCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEEEEEECCCCCCHHHEEEEEEEECCEEE
FYSGDYSAESNILRANLPEKLRGDIKVAIVDAAYHTDDVSQRERVNELCTEIERAAGNKG
EEECCCCCCCCEEECCCCHHHCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCC
IALLPLPPLGRAQDIVLYLYEKYKEFPIIVDQEILDGFDEMFLYKDWIKNNKELEELMES
EEEEECCCCCCHHHHHHHHHHHHCCCCEEECHHHHCCHHHHHHHHHHHCCCHHHHHHHHH
LKRNIIVMDDDGGTQHSCGIVVMSDANMQTKRAQLYYEQIRHEERNSIIFTGHVAKGSFA
HHCCEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHH
EKVLKERIGKECRVKRVPYKVHQSIRDVKEMLNTLLPEHTVLVHALKEDTDRLQKKLSTA
HHHHHHHCCCHHEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHC
GYENVYSLTMERIEVI
CCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]