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The map label for this gene is cheV [H]

Identifier: 49184587

GI number: 49184587

Start: 1593221

End: 1593709

Strand: Direct

Name: cheV [H]

Synonym: BAS1572

Alternate gene names: 49184587

Gene position: 1593221-1593709 (Clockwise)

Preceding gene: 49184586

Following gene: 49184588

Centisome position: 30.47

GC content: 33.74

Gene sequence:

>489_bases
TTGCTATTAGATTATGAAAAAATTGTATGTGAAATTAGCGGTACTGGTTATGACAATAAATCACTTGCAGGGTTAGAACA
GAAAACAGATCGAGCTGAAAAAGTTATTTATATTGCAGAAGATTCAGCAATGCTTCGCCAAATATTAGAAGAAACATTAT
CGTCAGCTGGATATACGAAAATGAACTTCTTCAGCAATGGTGCAGAAGCGTTAGCACAAATTGAAAAACTAGCGAAAGAG
CAAGGGGAAAAAATGTTTGAACATATTCACTTGCTAATTACTGATATTGAAATGCCGAAAATGGATGGGCATCATTTAAC
GAAAGCGGTTAAAGATAGTGAAGTAATGAATCGTTTACCAGTCATTATTTTCTCTTCATTAATTACAAATGAATTATTCC
ATAAAGGCGAAGCTGTAGGAGCAAATGCTCAAGTAAGTAAGCCAGATATTCAAGAGTTAATTGGTTTAGTAGATAAGCTA
GTGCTTTAA

Upstream 100 bases:

>100_bases
TTCAACGTATTTCGTGGGAACAAATTGATGAACCAGCTTCATTGTCTATGGGGCTAGAAGAAACGACATCTGGTATTGTA
AAGCTAGATGGCAAATTATT

Downstream 100 bases:

>100_bases
AAGCTTCTTTTTAGCTGGAATAGAGGAACTAGCCATGTGTGGAGCGGTCAGTGCTTAATAGAGCCCCATGCCATGTGAGA
CCAGAGATATGGAGTGGTTT

Product: CheY-like domain-containing protein

Products: NADP; 2 glutathione [C]

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MLLDYEKIVCEISGTGYDNKSLAGLEQKTDRAEKVIYIAEDSAMLRQILEETLSSAGYTKMNFFSNGAEALAQIEKLAKE
QGEKMFEHIHLLITDIEMPKMDGHHLTKAVKDSEVMNRLPVIIFSSLITNELFHKGEAVGANAQVSKPDIQELIGLVDKL
VL

Sequences:

>Translated_162_residues
MLLDYEKIVCEISGTGYDNKSLAGLEQKTDRAEKVIYIAEDSAMLRQILEETLSSAGYTKMNFFSNGAEALAQIEKLAKE
QGEKMFEHIHLLITDIEMPKMDGHHLTKAVKDSEVMNRLPVIIFSSLITNELFHKGEAVGANAQVSKPDIQELIGLVDKL
VL
>Mature_162_residues
MLLDYEKIVCEISGTGYDNKSLAGLEQKTDRAEKVIYIAEDSAMLRQILEETLSSAGYTKMNFFSNGAEALAQIEKLAKE
QGEKMFEHIHLLITDIEMPKMDGHHLTKAVKDSEVMNRLPVIIFSSLITNELFHKGEAVGANAQVSKPDIQELIGLVDKL
VL

Specific function: Chemotaxis involves both a phosphorylation-dependent excitation and a methylation-dependent adaptation. CheV and CheW function together to couple CheA activation to methyl-accepting chemotaxis protein receptor status and possible CheA-dependent phosphoryl

COG id: COG0784

COG function: function code T; FOG: CheY-like receiver

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545
- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01584 CheW; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 18052; Mature: 18052

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLDYEKIVCEISGTGYDNKSLAGLEQKTDRAEKVIYIAEDSAMLRQILEETLSSAGYTK
CCCCHHHHHEEECCCCCCCCCCCCHHHHHCHHHEEEEEECCHHHHHHHHHHHHHHCCCCH
MNFFSNGAEALAQIEKLAKEQGEKMFEHIHLLITDIEMPKMDGHHLTKAVKDSEVMNRLP
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
VIIFSSLITNELFHKGEAVGANAQVSKPDIQELIGLVDKLVL
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MLLDYEKIVCEISGTGYDNKSLAGLEQKTDRAEKVIYIAEDSAMLRQILEETLSSAGYTK
CCCCHHHHHEEECCCCCCCCCCCCHHHHHCHHHEEEEEECCHHHHHHHHHHHHHHCCCCH
MNFFSNGAEALAQIEKLAKEQGEKMFEHIHLLITDIEMPKMDGHHLTKAVKDSEVMNRLP
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
VIIFSSLITNELFHKGEAVGANAQVSKPDIQELIGLVDKLVL
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH2; oxidized glutathione [C]

Specific reaction: NADPH2 + oxidized glutathione = NADP + 2 glutathione [C]

General reaction: Oxidoreductases; Acting on NADH or NADPH; With a disulfide as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8169223; 9384377; 8169224 [H]