Click here to switch to the map view.

The map label for this gene is cheA [H]

Identifier: 49184558

GI number: 49184558

Start: 1569638

End: 1571044

Strand: Direct

Name: cheA [H]

Synonym: BAS1543

Alternate gene names: 49184558

Gene position: 1569638-1571044 (Clockwise)

Preceding gene: 49184557

Following gene: 49184559

Centisome position: 30.02

GC content: 35.18

Gene sequence:

>1407_bases
ATGGATACTGATCAAAGTGAAGAAGAATTAAAACAAGTAGTGCTTCATGTTTCTGAAATTGAGAAAGTAGAAGTGAAGCA
AGGACATACATCAAAAGAAGTAGTTTCGGAAAAATTGGTTACACAAGAAGTCGTACAAGAAGTTATACAAGCGGATACGC
ATGTGGAATCAACTAAAGAAGTATCTAAACAATCTGCTAATGCTACACCAGCTAAAAGCACTGGAAAAACGAAAAATGGT
AAAGTGGAAAATCGTTCCATACGTGTTCAATTAGAAAAAATTGAAAGATTAATGAACATGTTTGAAGAAAGTGTAATTGA
GCGTGGTCGCATAGATGAATTGGCGCAAGCAATTCAAAACAAAGAATTAATTGAGCATTTAAATCGATTAGGCGATATTT
CAAAAGATATTCAAAATGTACTTCTAAACATGCGTATGGTGCCGATTGAAACAGTCTTTAATCGTTTCCCGCGTATGGTA
CGTATGTTAGCGAAAGATTTAGGGGAAAAAATCGATTTACAAATTACAGGTGAAGATACTGAAGTCGATAAAATTGTTAT
TGATGAAATCGGTGATCCGCTTGTTCATTTAATTCGTAATGCAATTGATCATGGGGTTGAAACTGTTGAACAACGTCGTG
ATGCAGGTAAAAATGAGACAGGTACGATTAAATTAGAAGCGTTCCATAGTGGAAATCATGTCGTAATTCAAATTACGGAT
GATGGAAATGGAATTCATAAAGGGAAAGTATTAGAAAAAGCGATTAAAAATGGTGTTGTAACAGAATCTGAGGCAAATAA
ATTAACAGACCGTGAAATATTTGATTTGATCTTCCAACCAGGATTTAGTACAGCTGAAGTTGTATCAGACCTTTCTGGGC
GCGGGGTTGGATTAGATGTAGTGAAACATACAATTCATAGTTTAGGTGGACATTTAATTATTGATTCTGAAGAAGGCAAG
GGAAGTACATTTAGAATTGAACTTCCATTAACGTTGTCTATTATACAATCTATGCTTGTTCAAACGAATGATAAACGGTA
TGCTTTACCTCTTGGTAATATTGTTGAAGCAATTCGAATCAAGAGAGAAGACATCCAATCCATACAAGGAAAAGATGTGT
TAAATTACCGTAATCAAATTATTGAAGTGAAGCATTTAAGTACGGTATTTGGTGAGAAAACAGCAGATGAGGCGTTTGCG
TCATATGATGGTCAAATGGTTCCTGTGTTAATTGTTCGTAATACACATCGCAGCTATGGACTTATTGTAAACACAATTAT
CGGTCAAAGAGAAATAGTCTTAAAGTCATTAGGTGACTTCTTTGCAGAGAGTTCTAATTATTTCTCTGGTGCGACAATTC
TCGGTGATGGACGAGTGGTCCTCATTTTAAACCCAGAAGGTTTATAA

Upstream 100 bases:

>100_bases
TGTGTATTGAAGCGCTACAAAATTTAGGTAATGTAAAAAAACAGTTCCTAGTATTGAAGAAATTGAAGCAGATGCTTTCG
GGTTTGAGTTCACAGTATTT

Downstream 100 bases:

>100_bases
TAGGAATGAAGGAAAGCTCCCCACTTGTATACAATTGGGGAGCTTTTTGGTTAATCGTTACTAATCTGAAAATGGGAATA
AATACATATTAACGTTTTAT

Product: two component signalling adaptor domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MDTDQSEEELKQVVLHVSEIEKVEVKQGHTSKEVVSEKLVTQEVVQEVIQADTHVESTKEVSKQSANATPAKSTGKTKNG
KVENRSIRVQLEKIERLMNMFEESVIERGRIDELAQAIQNKELIEHLNRLGDISKDIQNVLLNMRMVPIETVFNRFPRMV
RMLAKDLGEKIDLQITGEDTEVDKIVIDEIGDPLVHLIRNAIDHGVETVEQRRDAGKNETGTIKLEAFHSGNHVVIQITD
DGNGIHKGKVLEKAIKNGVVTESEANKLTDREIFDLIFQPGFSTAEVVSDLSGRGVGLDVVKHTIHSLGGHLIIDSEEGK
GSTFRIELPLTLSIIQSMLVQTNDKRYALPLGNIVEAIRIKREDIQSIQGKDVLNYRNQIIEVKHLSTVFGEKTADEAFA
SYDGQMVPVLIVRNTHRSYGLIVNTIIGQREIVLKSLGDFFAESSNYFSGATILGDGRVVLILNPEGL

Sequences:

>Translated_468_residues
MDTDQSEEELKQVVLHVSEIEKVEVKQGHTSKEVVSEKLVTQEVVQEVIQADTHVESTKEVSKQSANATPAKSTGKTKNG
KVENRSIRVQLEKIERLMNMFEESVIERGRIDELAQAIQNKELIEHLNRLGDISKDIQNVLLNMRMVPIETVFNRFPRMV
RMLAKDLGEKIDLQITGEDTEVDKIVIDEIGDPLVHLIRNAIDHGVETVEQRRDAGKNETGTIKLEAFHSGNHVVIQITD
DGNGIHKGKVLEKAIKNGVVTESEANKLTDREIFDLIFQPGFSTAEVVSDLSGRGVGLDVVKHTIHSLGGHLIIDSEEGK
GSTFRIELPLTLSIIQSMLVQTNDKRYALPLGNIVEAIRIKREDIQSIQGKDVLNYRNQIIEVKHLSTVFGEKTADEAFA
SYDGQMVPVLIVRNTHRSYGLIVNTIIGQREIVLKSLGDFFAESSNYFSGATILGDGRVVLILNPEGL
>Mature_468_residues
MDTDQSEEELKQVVLHVSEIEKVEVKQGHTSKEVVSEKLVTQEVVQEVIQADTHVESTKEVSKQSANATPAKSTGKTKNG
KVENRSIRVQLEKIERLMNMFEESVIERGRIDELAQAIQNKELIEHLNRLGDISKDIQNVLLNMRMVPIETVFNRFPRMV
RMLAKDLGEKIDLQITGEDTEVDKIVIDEIGDPLVHLIRNAIDHGVETVEQRRDAGKNETGTIKLEAFHSGNHVVIQITD
DGNGIHKGKVLEKAIKNGVVTESEANKLTDREIFDLIFQPGFSTAEVVSDLSGRGVGLDVVKHTIHSLGGHLIIDSEEGK
GSTFRIELPLTLSIIQSMLVQTNDKRYALPLGNIVEAIRIKREDIQSIQGKDVLNYRNQIIEVKHLSTVFGEKTADEAFA
SYDGQMVPVLIVRNTHRSYGLIVNTIIGQREIVLKSLGDFFAESSNYFSGATILGDGRVVLILNPEGL

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=425, Percent_Identity=39.0588235294118, Blast_Score=293, Evalue=2e-80,
Organism=Escherichia coli, GI1790436, Length=248, Percent_Identity=27.8225806451613, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52129; Mature: 52129

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS50851 CHEW ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTDQSEEELKQVVLHVSEIEKVEVKQGHTSKEVVSEKLVTQEVVQEVIQADTHVESTKE
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
VSKQSANATPAKSTGKTKNGKVENRSIRVQLEKIERLMNMFEESVIERGRIDELAQAIQN
HHHHCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
KELIEHLNRLGDISKDIQNVLLNMRMVPIETVFNRFPRMVRMLAKDLGEKIDLQITGEDT
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
EVDKIVIDEIGDPLVHLIRNAIDHGVETVEQRRDAGKNETGTIKLEAFHSGNHVVIQITD
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEEEEEEC
DGNGIHKGKVLEKAIKNGVVTESEANKLTDREIFDLIFQPGFSTAEVVSDLSGRGVGLDV
CCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHH
VKHTIHSLGGHLIIDSEEGKGSTFRIELPLTLSIIQSMLVQTNDKRYALPLGNIVEAIRI
HHHHHHHCCCEEEEECCCCCCCEEEEEECHHHHHHHHHHHHCCCCEEECCHHHHHHHHHH
KREDIQSIQGKDVLNYRNQIIEVKHLSTVFGEKTADEAFASYDGQMVPVLIVRNTHRSYG
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEEEECCCCCCC
LIVNTIIGQREIVLKSLGDFFAESSNYFSGATILGDGRVVLILNPEGL
HHHHHHHCHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEEEECCCCC
>Mature Secondary Structure
MDTDQSEEELKQVVLHVSEIEKVEVKQGHTSKEVVSEKLVTQEVVQEVIQADTHVESTKE
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
VSKQSANATPAKSTGKTKNGKVENRSIRVQLEKIERLMNMFEESVIERGRIDELAQAIQN
HHHHCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
KELIEHLNRLGDISKDIQNVLLNMRMVPIETVFNRFPRMVRMLAKDLGEKIDLQITGEDT
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
EVDKIVIDEIGDPLVHLIRNAIDHGVETVEQRRDAGKNETGTIKLEAFHSGNHVVIQITD
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCEEEEEEEC
DGNGIHKGKVLEKAIKNGVVTESEANKLTDREIFDLIFQPGFSTAEVVSDLSGRGVGLDV
CCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHH
VKHTIHSLGGHLIIDSEEGKGSTFRIELPLTLSIIQSMLVQTNDKRYALPLGNIVEAIRI
HHHHHHHCCCEEEEECCCCCCCEEEEEECHHHHHHHHHHHHCCCCEEECCHHHHHHHHHH
KREDIQSIQGKDVLNYRNQIIEVKHLSTVFGEKTADEAFASYDGQMVPVLIVRNTHRSYG
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEEEECCCCCCC
LIVNTIIGQREIVLKSLGDFFAESSNYFSGATILGDGRVVLILNPEGL
HHHHHHHCHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]