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The map label for this gene is sipW [H]

Identifier: 49184209

GI number: 49184209

Start: 1236294

End: 1236863

Strand: Direct

Name: sipW [H]

Synonym: BAS1191

Alternate gene names: 49184209

Gene position: 1236294-1236863 (Clockwise)

Preceding gene: 49184208

Following gene: 49184210

Centisome position: 23.64

GC content: 35.61

Gene sequence:

>570_bases
ATGAAATTAATTTGGAAGGTGATTAGCAACGTTATCTCATTTGTTTTATTTGCGTTAATGGTTTGCTTAGCTTTTGTAGT
TATTTCTTCAAAAGCGAGCGGTGGTGATCCAACGGTGATGGGATATCAATTTAAGAGCGTTCTTTCAGGATCGATGGAAC
CAACATTTTTAACAGGATCAATCATTGCGATAGAGCCGACGAAAGATGGTTCTAAATATCAAAAAGGTGATGTTATTACT
TTTAAAGAGAAAGATGAAAAAATTATCACTCACCGTATTATCGGTGTAAAAGATACAAATGGAAAAGTAATGTATGAAAC
AAAAGGAGACAACAACAACGGGCCAGATTTAGAACCGGTACTTGCGGAGAATGTTATTGGGAAATATGCAGATATTACAG
TTCCTTATGCAGGGTATGCATTAAATTATGCGAATTCAAAAGCGGGAGCAGCTTTGCTTCTTATTATTCCAGGAGTCTTT
TTACTAGGTTATTCCGCTATTACTATTTTTAGTGCGATTCGTAGCATTGATGGAGAAAAGAAAGAGAAAAAAGTAGAACA
ATCCGTCTAG

Upstream 100 bases:

>100_bases
TAATGTGTTCGTTATATTATTTAGTTGTGTTCTCGTTAAAGAACGAAACTGAATATTGCATACTTCAAATAATATAAAAC
AACGGAGAGGGAGAGAAACG

Downstream 100 bases:

>100_bases
TTTGTTTGGTTATACTTTCCGATTAGGAAGTTGACAAATATATAGATTAAGGGGATATGGACATGACTTTAAAGAAAAAA
TTAGGAATGGGTATCGCATC

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MKLIWKVISNVISFVLFALMVCLAFVVISSKASGGDPTVMGYQFKSVLSGSMEPTFLTGSIIAIEPTKDGSKYQKGDVIT
FKEKDEKIITHRIIGVKDTNGKVMYETKGDNNNGPDLEPVLAENVIGKYADITVPYAGYALNYANSKAGAALLLIIPGVF
LLGYSAITIFSAIRSIDGEKKEKKVEQSV

Sequences:

>Translated_189_residues
MKLIWKVISNVISFVLFALMVCLAFVVISSKASGGDPTVMGYQFKSVLSGSMEPTFLTGSIIAIEPTKDGSKYQKGDVIT
FKEKDEKIITHRIIGVKDTNGKVMYETKGDNNNGPDLEPVLAENVIGKYADITVPYAGYALNYANSKAGAALLLIIPGVF
LLGYSAITIFSAIRSIDGEKKEKKVEQSV
>Mature_189_residues
MKLIWKVISNVISFVLFALMVCLAFVVISSKASGGDPTVMGYQFKSVLSGSMEPTFLTGSIIAIEPTKDGSKYQKGDVIT
FKEKDEKIITHRIIGVKDTNGKVMYETKGDNNNGPDLEPVLAENVIGKYADITVPYAGYALNYANSKAGAALLLIIPGVF
LLGYSAITIFSAIRSIDGEKKEKKVEQSV

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056
- InterPro:   IPR001733 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 20450; Mature: 20450

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: PS00061 ADH_SHORT ; PS00501 SPASE_I_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIWKVISNVISFVLFALMVCLAFVVISSKASGGDPTVMGYQFKSVLSGSMEPTFLTGS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHCCCCCCEEEECE
IIAIEPTKDGSKYQKGDVITFKEKDEKIITHRIIGVKDTNGKVMYETKGDNNNGPDLEPV
EEEEECCCCCCCCCCCCEEEECCCCCEEEEHEEEEEEECCCEEEEEECCCCCCCCCCCHH
LAENVIGKYADITVPYAGYALNYANSKAGAALLLIIPGVFLLGYSAITIFSAIRSIDGEK
HHHHHHCCHHCEECCCCCEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCHH
KEKKVEQSV
HHHHHHHCC
>Mature Secondary Structure
MKLIWKVISNVISFVLFALMVCLAFVVISSKASGGDPTVMGYQFKSVLSGSMEPTFLTGS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHCCCCCCEEEECE
IIAIEPTKDGSKYQKGDVITFKEKDEKIITHRIIGVKDTNGKVMYETKGDNNNGPDLEPV
EEEEECCCCCCCCCCCCEEEECCCCCEEEEHEEEEEEECCCEEEEEECCCCCCCCCCCHH
LAENVIGKYADITVPYAGYALNYANSKAGAALLLIIPGVFLLGYSAITIFSAIRSIDGEK
HHHHHHCCHHCEECCCCCEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCHH
KEKKVEQSV
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9823656 [H]