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The map label for this gene is mcpB [H]

Identifier: 49184066

GI number: 49184066

Start: 1098721

End: 1100448

Strand: Direct

Name: mcpB [H]

Synonym: BAS1046

Alternate gene names: 49184066

Gene position: 1098721-1100448 (Clockwise)

Preceding gene: 49184065

Following gene: 49184067

Centisome position: 21.01

GC content: 33.91

Gene sequence:

>1728_bases
ATGTATTTTTTACAAAATTTAAAAGTGAAATATAAATTATTGTCACTTATTTCATTAGCAGTTTTAGGCATGGTAATTAT
GAGCTATGTAGCAATTCAGTCTATTAATAAGATTAAGCAAAATACAGAGGTTGTAGTAGATGATTATCAATATTCTACAA
TTTTATTAGAAGGGATGCTTCGTACACAAAATTCACTAGAATATAACTTATTAGAATTAATTACGACATCACAAAATGAA
GGGACAAATAAAGAGGAGATAATTGATAATATTGAAAAGGATCTTAAAAAATATGATTCTTTATTAAAAGAATATGATGA
TGGCTTTAATTTAAGTAAGCAAGAGGATGAACTGTTTCAGGAGATGAAGAAATCTTTGCCAATTTATATGGGTACATATA
AAAAATTGTTTGAAAAGGCGAAGGTAAAAAACGAGTCACAAATGGTAAACGAATTTCAGAAGGAATTAAAACCGAGGGGA
GTAGAGTTAGCTGGATATGCGGTGGATCTAGAATCGTATGTTTCAAACTTAGCTGATCAAGTATTTAATGATTCTCAAAA
AATGATAGATCGGTCAGTTATTACTTTTATCATTCTCGTAGTAGTTACTACAATCGTTATATGTATAGTAAGTTATAGTA
TTAGCAGGCTTATAGTTGCTCCTTTACAAACAGTTAGTCGTATGATGGAAAGAGCAAAAAATGGGGATTTAACTGTACAT
GGTGAGTATAATGCTAAAGATGAATTAGGTGTATTAGTAAGTGATTTTAATGAAATGATTACAGGGCTAAGAACAAATAT
GAAAGAAGTAGATAATAACATTCAGCTTTTATTCCAACATGCAGACGGAGTAGTATCTGCATCAGAAGTATCTAGCAGTG
CGGCGGAGAAAATAACGATGGATATTGAAGAAGTTGCAAATGGTGCAGAGAGCCAAATGCAAGCAATGGAACAAACTGCA
GGTGCGATGGAAGAGTTGACACAGGGAATGCAGAGTATAGTGAATACATCATCATCTGTAAATGAATTGTCTGCTCAATC
AGCATTAGATGCAGAGAGTGGTAATAAGTTAATGAAACAAATGATTCAACAGATGAATATAATCCAAAATTCAGTACATA
GCGGTGTTAAACAAGTAGAGACTATGAAAGAACAATCAGAAGAAATTGTTAAAATCATTGATGTTATGCAAGGTATTGCC
TCTCAGATTAACTTATTAGCATTAAATGCCGCAATTGAGGCTGCCCGTGCTGGGGAAAGTGGTAGAGGGTTTGCAATTGT
CGCAGATGAAGTGCGGAAATTAGCGGAACAATCTAGTAATTCTGCAAAACAAATTGAGAAGCTTATTACTCAAGTTATGG
GAACAACGAGCCATACGGTACATATGATGGAGAGAGTAGATAATGAGGTACAGGCAGGTACACAAGTGGTAATGGATACA
GAAAAAGTATTTGGAAAAATTACAGAAAAAGTACATCAAGTATCTGAGCAAATTCAAACGGTATCTATGTCTACAGATGA
AATTGCAGCAAGTAGTGAGGAGATTTCAGCTTCGGCAGAAGACATGGCTCAAATTTCCCAAAGATCATCTGACCGAACTG
ATAGGGTAAAAGAGTCTATTCAACAGCAAGAAAAATCTGTTCAAGAGATTTCGGTTTCAATTGAACATATGCATAACGCA
GCAGGAAAACTAAAACAAATAGTTGCCCAATTTACTCTTCAAAAGTAG

Upstream 100 bases:

>100_bases
TTGATATTGGGAATATTTATCATTGCTTTTTATTGTGATTTTGTAAATAATAAGCTATAAAATTCTAAAAATCTATATAT
AAAGGAATAAAGGTGGAAAA

Downstream 100 bases:

>100_bases
TAGTATATTTCAGTTTTAATATAGAGAAATTCCTCTCAATAAATAAAAAAATCATCCCATGTAAAAAAGGATGATTTTTT
TATGGAAATTTTGTACGGCT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: H3 [H]

Number of amino acids: Translated: 575; Mature: 575

Protein sequence:

>575_residues
MYFLQNLKVKYKLLSLISLAVLGMVIMSYVAIQSINKIKQNTEVVVDDYQYSTILLEGMLRTQNSLEYNLLELITTSQNE
GTNKEEIIDNIEKDLKKYDSLLKEYDDGFNLSKQEDELFQEMKKSLPIYMGTYKKLFEKAKVKNESQMVNEFQKELKPRG
VELAGYAVDLESYVSNLADQVFNDSQKMIDRSVITFIILVVVTTIVICIVSYSISRLIVAPLQTVSRMMERAKNGDLTVH
GEYNAKDELGVLVSDFNEMITGLRTNMKEVDNNIQLLFQHADGVVSASEVSSSAAEKITMDIEEVANGAESQMQAMEQTA
GAMEELTQGMQSIVNTSSSVNELSAQSALDAESGNKLMKQMIQQMNIIQNSVHSGVKQVETMKEQSEEIVKIIDVMQGIA
SQINLLALNAAIEAARAGESGRGFAIVADEVRKLAEQSSNSAKQIEKLITQVMGTTSHTVHMMERVDNEVQAGTQVVMDT
EKVFGKITEKVHQVSEQIQTVSMSTDEIAASSEEISASAEDMAQISQRSSDRTDRVKESIQQQEKSVQEISVSIEHMHNA
AGKLKQIVAQFTLQK

Sequences:

>Translated_575_residues
MYFLQNLKVKYKLLSLISLAVLGMVIMSYVAIQSINKIKQNTEVVVDDYQYSTILLEGMLRTQNSLEYNLLELITTSQNE
GTNKEEIIDNIEKDLKKYDSLLKEYDDGFNLSKQEDELFQEMKKSLPIYMGTYKKLFEKAKVKNESQMVNEFQKELKPRG
VELAGYAVDLESYVSNLADQVFNDSQKMIDRSVITFIILVVVTTIVICIVSYSISRLIVAPLQTVSRMMERAKNGDLTVH
GEYNAKDELGVLVSDFNEMITGLRTNMKEVDNNIQLLFQHADGVVSASEVSSSAAEKITMDIEEVANGAESQMQAMEQTA
GAMEELTQGMQSIVNTSSSVNELSAQSALDAESGNKLMKQMIQQMNIIQNSVHSGVKQVETMKEQSEEIVKIIDVMQGIA
SQINLLALNAAIEAARAGESGRGFAIVADEVRKLAEQSSNSAKQIEKLITQVMGTTSHTVHMMERVDNEVQAGTQVVMDT
EKVFGKITEKVHQVSEQIQTVSMSTDEIAASSEEISASAEDMAQISQRSSDRTDRVKESIQQQEKSVQEISVSIEHMHNA
AGKLKQIVAQFTLQK
>Mature_575_residues
MYFLQNLKVKYKLLSLISLAVLGMVIMSYVAIQSINKIKQNTEVVVDDYQYSTILLEGMLRTQNSLEYNLLELITTSQNE
GTNKEEIIDNIEKDLKKYDSLLKEYDDGFNLSKQEDELFQEMKKSLPIYMGTYKKLFEKAKVKNESQMVNEFQKELKPRG
VELAGYAVDLESYVSNLADQVFNDSQKMIDRSVITFIILVVVTTIVICIVSYSISRLIVAPLQTVSRMMERAKNGDLTVH
GEYNAKDELGVLVSDFNEMITGLRTNMKEVDNNIQLLFQHADGVVSASEVSSSAAEKITMDIEEVANGAESQMQAMEQTA
GAMEELTQGMQSIVNTSSSVNELSAQSALDAESGNKLMKQMIQQMNIIQNSVHSGVKQVETMKEQSEEIVKIIDVMQGIA
SQINLLALNAAIEAARAGESGRGFAIVADEVRKLAEQSSNSAKQIEKLITQVMGTTSHTVHMMERVDNEVQAGTQVVMDT
EKVFGKITEKVHQVSEQIQTVSMSTDEIAASSEEISASAEDMAQISQRSSDRTDRVKESIQQQEKSVQEISVSIEHMHNA
AGKLKQIVAQFTLQK

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=492, Percent_Identity=26.8292682926829, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI2367378, Length=540, Percent_Identity=24.0740740740741, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1788194, Length=415, Percent_Identity=28.9156626506024, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1788195, Length=320, Percent_Identity=27.5, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1789453, Length=342, Percent_Identity=26.3157894736842, Blast_Score=102, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 64036; Mature: 64036

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYFLQNLKVKYKLLSLISLAVLGMVIMSYVAIQSINKIKQNTEVVVDDYQYSTILLEGML
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHH
RTQNSLEYNLLELITTSQNEGTNKEEIIDNIEKDLKKYDSLLKEYDDGFNLSKQEDELFQ
HHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
EMKKSLPIYMGTYKKLFEKAKVKNESQMVNEFQKELKPRGVELAGYAVDLESYVSNLADQ
HHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
VFNDSQKMIDRSVITFIILVVVTTIVICIVSYSISRLIVAPLQTVSRMMERAKNGDLTVH
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
GEYNAKDELGVLVSDFNEMITGLRTNMKEVDNNIQLLFQHADGVVSASEVSSSAAEKITM
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHH
DIEEVANGAESQMQAMEQTAGAMEELTQGMQSIVNTSSSVNELSAQSALDAESGNKLMKQ
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHH
MIQQMNIIQNSVHSGVKQVETMKEQSEEIVKIIDVMQGIASQINLLALNAAIEAARAGES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GRGFAIVADEVRKLAEQSSNSAKQIEKLITQVMGTTSHTVHMMERVDNEVQAGTQVVMDT
CCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHH
EKVFGKITEKVHQVSEQIQTVSMSTDEIAASSEEISASAEDMAQISQRSSDRTDRVKESI
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHCCHHHHHHHHHCCCCHHHHHHHHH
QQQEKSVQEISVSIEHMHNAAGKLKQIVAQFTLQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYFLQNLKVKYKLLSLISLAVLGMVIMSYVAIQSINKIKQNTEVVVDDYQYSTILLEGML
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHH
RTQNSLEYNLLELITTSQNEGTNKEEIIDNIEKDLKKYDSLLKEYDDGFNLSKQEDELFQ
HHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
EMKKSLPIYMGTYKKLFEKAKVKNESQMVNEFQKELKPRGVELAGYAVDLESYVSNLADQ
HHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
VFNDSQKMIDRSVITFIILVVVTTIVICIVSYSISRLIVAPLQTVSRMMERAKNGDLTVH
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
GEYNAKDELGVLVSDFNEMITGLRTNMKEVDNNIQLLFQHADGVVSASEVSSSAAEKITM
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHH
DIEEVANGAESQMQAMEQTAGAMEELTQGMQSIVNTSSSVNELSAQSALDAESGNKLMKQ
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHH
MIQQMNIIQNSVHSGVKQVETMKEQSEEIVKIIDVMQGIASQINLLALNAAIEAARAGES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GRGFAIVADEVRKLAEQSSNSAKQIEKLITQVMGTTSHTVHMMERVDNEVQAGTQVVMDT
CCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHH
EKVFGKITEKVHQVSEQIQTVSMSTDEIAASSEEISASAEDMAQISQRSSDRTDRVKESI
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHCCHHHHHHHHHCCCCHHHHHHHHH
QQQEKSVQEISVSIEHMHNAAGKLKQIVAQFTLQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]