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The map label for this gene is dhaK [H]

Identifier: 49183928

GI number: 49183928

Start: 966359

End: 967357

Strand: Reverse

Name: dhaK [H]

Synonym: BAS0905

Alternate gene names: 49183928

Gene position: 967357-966359 (Counterclockwise)

Preceding gene: 49183929

Following gene: 49183921

Centisome position: 18.5

GC content: 39.24

Gene sequence:

>999_bases
ATGAAAAAGATTATGAATGATGTACAAAATATCGTTCAAGATATGCTGCATGGCTTTTATTTTGAACATAACGACAAAGT
AAATTATGACGAAACAAATAACATCATTTATGTAAAAGATATCGAAAAACTGAAGCAAGACGTCGCTATAATAAGCGGCG
GTGGTAGTGGACATGAACCAGCTGATATTGGTTATGTAGGAAAAGGAATGCTTACAGCGGCAGTAAACGGCAGTATTTTT
ACTCCGCCTACAGTGGAACAAATTGTAGCGGCTACTCGCCTCATGCCAAAAGAAAAAAGTATACTATTCATCATAAAAAA
CTTTAAAGATGACGTAGCTAACTTTGTAGCGGCAGAACAAATCGCAAAAGAAGAAGGAAGAGAAATTGACCACATCATCG
TAAATGACGACGTTTCAATTGAAGATGATGCTTCGTTTACTAAAAGAAGACGCGGTGTTGCTGGTACTGTTTTCGTTCAA
AAAATACTTGGTGCGGCTGCTCTTGAAGGTCATTCTTTAGAAGAACTAACAACACTCGGCTGTTCTGTTACCGAGAACTT
ACACACATTAGGAGTCGCCCTTTCACCTGCAAACGATCCAGTGAAAGGACAAGCTTCATTCACATTAAACGAAGATGAAG
TCTTTTACGGCGTCGGCATTCACGGAGAAAAAGGTTACCGTAAAGAAGCACTATCCTCTTCTGAAATATTAGCGATTGAA
CTAATGAACAAACTTAAAAGCATTTATCGCTGGAGAAAAGGCGACAACTTCGCCATCCTTATTAATGGACTCGGCGCAAC
ACCATTAATGGAACAATACATTTTCGCAAATGACATTCGCCGTTTGTGTGAGCTGGAAGGATTACAGATTACATTCGTAA
AGGTCGGTACACTGTTAACTTCTTTAGATATGAAAGGTGTTTCACTCAGTTTGCTTAAGATAGAAGATTGGGATTGGGTG
AAGTGGTTAAAGGCGGATACTCGAGTGGGTAGTTGGTAA

Upstream 100 bases:

>100_bases
GATCCGTCCATTATGTCTTCTCTCATGAAAAATATGATAAACAATCAATTACTACTATTACTGGAGCAATCAGCAAAGTA
ATTAAAGGGTGGCAAAAGCA

Downstream 100 bases:

>100_bases
GTAAAAATTATGATGATAAAAGCCTTTAACTATAACAAGTTAAAGGCTTTTTGCAAATTGAAATATCGCACGAGCGTTCA
AAAGAAATTCGTAATCACCT

Product: DhaKLM operon coactivator DhaQ

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MKKIMNDVQNIVQDMLHGFYFEHNDKVNYDETNNIIYVKDIEKLKQDVAIISGGGSGHEPADIGYVGKGMLTAAVNGSIF
TPPTVEQIVAATRLMPKEKSILFIIKNFKDDVANFVAAEQIAKEEGREIDHIIVNDDVSIEDDASFTKRRRGVAGTVFVQ
KILGAAALEGHSLEELTTLGCSVTENLHTLGVALSPANDPVKGQASFTLNEDEVFYGVGIHGEKGYRKEALSSSEILAIE
LMNKLKSIYRWRKGDNFAILINGLGATPLMEQYIFANDIRRLCELEGLQITFVKVGTLLTSLDMKGVSLSLLKIEDWDWV
KWLKADTRVGSW

Sequences:

>Translated_332_residues
MKKIMNDVQNIVQDMLHGFYFEHNDKVNYDETNNIIYVKDIEKLKQDVAIISGGGSGHEPADIGYVGKGMLTAAVNGSIF
TPPTVEQIVAATRLMPKEKSILFIIKNFKDDVANFVAAEQIAKEEGREIDHIIVNDDVSIEDDASFTKRRRGVAGTVFVQ
KILGAAALEGHSLEELTTLGCSVTENLHTLGVALSPANDPVKGQASFTLNEDEVFYGVGIHGEKGYRKEALSSSEILAIE
LMNKLKSIYRWRKGDNFAILINGLGATPLMEQYIFANDIRRLCELEGLQITFVKVGTLLTSLDMKGVSLSLLKIEDWDWV
KWLKADTRVGSW
>Mature_332_residues
MKKIMNDVQNIVQDMLHGFYFEHNDKVNYDETNNIIYVKDIEKLKQDVAIISGGGSGHEPADIGYVGKGMLTAAVNGSIF
TPPTVEQIVAATRLMPKEKSILFIIKNFKDDVANFVAAEQIAKEEGREIDHIIVNDDVSIEDDASFTKRRRGVAGTVFVQ
KILGAAALEGHSLEELTTLGCSVTENLHTLGVALSPANDPVKGQASFTLNEDEVFYGVGIHGEKGYRKEALSSSEILAIE
LMNKLKSIYRWRKGDNFAILINGLGATPLMEQYIFANDIRRLCELEGLQITFVKVGTLLTSLDMKGVSLSLLKIEDWDWV
KWLKADTRVGSW

Specific function: Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaK domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=342, Percent_Identity=33.9181286549708, Blast_Score=192, Evalue=3e-49,
Organism=Escherichia coli, GI87081857, Length=347, Percent_Identity=35.4466858789625, Blast_Score=218, Evalue=5e-58,
Organism=Caenorhabditis elegans, GI17565018, Length=331, Percent_Identity=32.6283987915408, Blast_Score=175, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6323570, Length=324, Percent_Identity=32.4074074074074, Blast_Score=134, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6321055, Length=296, Percent_Identity=30.4054054054054, Blast_Score=132, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR012736 [H]

Pfam domain/function: PF02733 Dak1 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 36796; Mature: 36796

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIMNDVQNIVQDMLHGFYFEHNDKVNYDETNNIIYVKDIEKLKQDVAIISGGGSGHEP
CHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCEEEEHHHHHHHHCEEEEECCCCCCCC
ADIGYVGKGMLTAAVNGSIFTPPTVEQIVAATRLMPKEKSILFIIKNFKDDVANFVAAEQ
CCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHH
IAKEEGREIDHIIVNDDVSIEDDASFTKRRRGVAGTVFVQKILGAAALEGHSLEELTTLG
HHHHCCCCCCEEEECCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHC
CSVTENLHTLGVALSPANDPVKGQASFTLNEDEVFYGVGIHGEKGYRKEALSSSEILAIE
CHHHCCCEEEEEEECCCCCCCCCCEEEEECCCCEEEEEEECCCCCCHHHHCCCCCCHHHH
LMNKLKSIYRWRKGDNFAILINGLGATPLMEQYIFANDIRRLCELEGLQITFVKVGTLLT
HHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHH
SLDMKGVSLSLLKIEDWDWVKWLKADTRVGSW
HCCCCCCEEEEEEECCCCHHHHHHHCCCCCCC
>Mature Secondary Structure
MKKIMNDVQNIVQDMLHGFYFEHNDKVNYDETNNIIYVKDIEKLKQDVAIISGGGSGHEP
CHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCEEEEHHHHHHHHCEEEEECCCCCCCC
ADIGYVGKGMLTAAVNGSIFTPPTVEQIVAATRLMPKEKSILFIIKNFKDDVANFVAAEQ
CCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHH
IAKEEGREIDHIIVNDDVSIEDDASFTKRRRGVAGTVFVQKILGAAALEGHSLEELTTLG
HHHHCCCCCCEEEECCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHC
CSVTENLHTLGVALSPANDPVKGQASFTLNEDEVFYGVGIHGEKGYRKEALSSSEILAIE
CHHHCCCEEEEEEECCCCCCCCCCEEEEECCCCEEEEEEECCCCCCHHHHCCCCCCHHHH
LMNKLKSIYRWRKGDNFAILINGLGATPLMEQYIFANDIRRLCELEGLQITFVKVGTLLT
HHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHH
SLDMKGVSLSLLKIEDWDWVKWLKADTRVGSW
HCCCCCCEEEEEEECCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]