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The map label for this gene is tcyB [H]

Identifier: 49183837

GI number: 49183837

Start: 864484

End: 865191

Strand: Direct

Name: tcyB [H]

Synonym: BAS0813

Alternate gene names: 49183837

Gene position: 864484-865191 (Clockwise)

Preceding gene: 49183836

Following gene: 49183838

Centisome position: 16.53

GC content: 36.58

Gene sequence:

>708_bases
TTGGTGAAAATGTATCTAAGTAGTGCATTGATTTCAGATCGATTGTCTACTTGGATAGATATTATGCAGACTTCCTTCAT
GCCTATGCTGAAGGAAGCTGTTTTTACGACAATTCCATTAACGCTTATTACATTTATTATCGGTCTTATACTGGCAACGT
TAACGGCGCTTGCACGTATTTCAGGTAGTCGTATTTTACAATGGATTGCTCGTATCTATGTATCTATCATTCGCGGAACG
CCACTTCTTGTACAGTTATTTATTATTTTCTATGGTCTGCCAACTCTTAATGTTGAAGTTGAGCCATATACAGCAGCAGT
GATTGGATTTTCATTAAATGTCGGTGCATATGCATCTGAAATTATTCGTGCTTCTATTCTTTCGATTCCGAAAGGGCAGT
GGGAAGCAGCTTATACAATTGGGATGACATACCCACAAGCGTTAAAACGTGTTATTTTACCGCAAGCAACGCGTGTATCA
ATTCCGCCGCTTTCGAATACATTTATTAGCTTAGTGAAAGATACTTCATTAGCATCGTTAATTTTAGTAACAGAAATGTT
CCGAAAAGCGCAGGAAATTGCGGCAATGAACTATGAGTTTTTAATTGTTTATTTTGAAGCAGGTCTTATTTATTGGGTTA
TTTGTTTCTTATTATCAATCGTACAACAGATGTTAGAAAAGCGCTCAGAACGCTACACATTAAAATAA

Upstream 100 bases:

>100_bases
TTATTCCGTAAAGGTAGCACTAAGCTTGTACAAGAAGTAGATAAAGCGTTAGAAGATATGAAAAAAGACGGTACGTATGA
CAAAATAACGAAAAAATGGT

Downstream 100 bases:

>100_bases
TCCTTTTACAAAAGGAGTTTTTGTTTTTATGATTTCAATTCAGCACTTACAAAAAAGTTTCGGAGATAATACCGTACTAA
AGCATATAGATTTAACAGTT

Product: amino acid ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MVKMYLSSALISDRLSTWIDIMQTSFMPMLKEAVFTTIPLTLITFIIGLILATLTALARISGSRILQWIARIYVSIIRGT
PLLVQLFIIFYGLPTLNVEVEPYTAAVIGFSLNVGAYASEIIRASILSIPKGQWEAAYTIGMTYPQALKRVILPQATRVS
IPPLSNTFISLVKDTSLASLILVTEMFRKAQEIAAMNYEFLIVYFEAGLIYWVICFLLSIVQQMLEKRSERYTLK

Sequences:

>Translated_235_residues
MVKMYLSSALISDRLSTWIDIMQTSFMPMLKEAVFTTIPLTLITFIIGLILATLTALARISGSRILQWIARIYVSIIRGT
PLLVQLFIIFYGLPTLNVEVEPYTAAVIGFSLNVGAYASEIIRASILSIPKGQWEAAYTIGMTYPQALKRVILPQATRVS
IPPLSNTFISLVKDTSLASLILVTEMFRKAQEIAAMNYEFLIVYFEAGLIYWVICFLLSIVQQMLEKRSERYTLK
>Mature_235_residues
MVKMYLSSALISDRLSTWIDIMQTSFMPMLKEAVFTTIPLTLITFIIGLILATLTALARISGSRILQWIARIYVSIIRGT
PLLVQLFIIFYGLPTLNVEVEPYTAAVIGFSLNVGAYASEIIRASILSIPKGQWEAAYTIGMTYPQALKRVILPQATRVS
IPPLSNTFISLVKDTSLASLILVTEMFRKAQEIAAMNYEFLIVYFEAGLIYWVICFLLSIVQQMLEKRSERYTLK

Specific function: Part of the ABC transporter complex tcyABC involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable) [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788226, Length=205, Percent_Identity=50.2439024390244, Blast_Score=205, Evalue=2e-54,
Organism=Escherichia coli, GI1787030, Length=204, Percent_Identity=36.7647058823529, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1787086, Length=214, Percent_Identity=32.7102803738318, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1786873, Length=211, Percent_Identity=33.6492890995261, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787087, Length=233, Percent_Identity=29.1845493562232, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87082239, Length=200, Percent_Identity=37, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1788645, Length=226, Percent_Identity=29.646017699115, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1788646, Length=218, Percent_Identity=27.5229357798165, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1786874, Length=184, Percent_Identity=29.3478260869565, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI48994930, Length=122, Percent_Identity=38.5245901639344, Blast_Score=74, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 26463; Mature: 26463

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKMYLSSALISDRLSTWIDIMQTSFMPMLKEAVFTTIPLTLITFIIGLILATLTALARI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGSRILQWIARIYVSIIRGTPLLVQLFIIFYGLPTLNVEVEPYTAAVIGFSLNVGAYASE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCHHEEEEEEECCCHHHHHH
IIRASILSIPKGQWEAAYTIGMTYPQALKRVILPQATRVSIPPLSNTFISLVKDTSLASL
HHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHH
ILVTEMFRKAQEIAAMNYEFLIVYFEAGLIYWVICFLLSIVQQMLEKRSERYTLK
HHHHHHHHHHHHHHHCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MVKMYLSSALISDRLSTWIDIMQTSFMPMLKEAVFTTIPLTLITFIIGLILATLTALARI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGSRILQWIARIYVSIIRGTPLLVQLFIIFYGLPTLNVEVEPYTAAVIGFSLNVGAYASE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCHHEEEEEEECCCHHHHHH
IIRASILSIPKGQWEAAYTIGMTYPQALKRVILPQATRVSIPPLSNTFISLVKDTSLASL
HHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHH
ILVTEMFRKAQEIAAMNYEFLIVYFEAGLIYWVICFLLSIVQQMLEKRSERYTLK
HHHHHHHHHHHHHHHCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 8969502; 9384377 [H]