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The map label for this gene is murQ

Identifier: 49183807

GI number: 49183807

Start: 833925

End: 834809

Strand: Direct

Name: murQ

Synonym: BAS0783

Alternate gene names: 49183807

Gene position: 833925-834809 (Clockwise)

Preceding gene: 49183806

Following gene: 49183808

Centisome position: 15.95

GC content: 38.98

Gene sequence:

>885_bases
ATGTTAGAGAATTTATCGACAGAACATCGCAATGAGAAGACGATGAATTTAGATGAGATGAACATAAAAGAAGTTCTGCA
AAGTATGAATGAAGAAGATCGAACTGTTGCATTAGCAGTTGAAAAAGAGATAGAACATATTGAAAAGGTTGTGCGGGTTG
TTATTCAATCTTTTGAAGAAGAGGGCCGATTAATTTACATTGGGGCTGGCACGAGTGGCCGTTTAGGTATTTTGGACGCA
GTGGAATGCCCGCCGACATTTGGCACAGATGATAAAATGGTGCAAGGATTTATAGCAGGTGGATTGAAAGCGTTTACTAA
AGCGGTGGAAGGTGCTGAAGATCGCGAAGAGTTAGCAGAAGAAGATTTAAAAAGTATTGGATTAAACGAGAAAGATACTG
TAATTGGAATTGCGGCAAGTGGCCGAACTCCTTATGTAATTGGCGGCTTGAAGTACGCGAATAGCGTGGGAGCGAGTACA
GCTAGTATCTCTTGTAATAAAAATGCTGAAATAAGTAAATATGCAAAACTAAATGTGGAAGTAGAAACAGGCGCAGAAAT
TTTAACAGGTTCAACGCGGTTGAAGGCTGGTACAGCGCAAAAATTAGTACTGAATATGATTTCAACAGCTTCTATGATTG
GTGTTGGAAAAGTATATAAAAATTTAATGGTAGATGTGCAATCTACGAATGAAAAGTTAGTAGAACGATCAAAACGAATT
ATTGTGGAAGCAACAGGGGTTAGTTATGAAGTAGCAGCAGAGCATTATGAAAAAGCAGAACGTAACGTGAAAGCTGCGAT
TGTTATGGTGCTATTGCAGTGTGAGTATGGGGAAGCACTGGAGAAACTAAAACAAGCAAAAGGGTTTGTGAAGAAGGCAT
TATAA

Upstream 100 bases:

>100_bases
AAAAGAAATGAAATTTCATAAAATAATAAAGTGATATTGATTTTAAATTTCTTAAAGTTATAATAAAAGTATGAAATTAA
ATTTTAAAGTAGGTGGGAAT

Downstream 100 bases:

>100_bases
AATAATAGGGAGGGGGATTCTATTATGAAGAAAGAAGAGAGAATGGCGAAAGAAATTTCAGAGCAACTTGGGGGAGTAAA
AAATATTCGTGGCATTGCTC

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MLENLSTEHRNEKTMNLDEMNIKEVLQSMNEEDRTVALAVEKEIEHIEKVVRVVIQSFEEEGRLIYIGAGTSGRLGILDA
VECPPTFGTDDKMVQGFIAGGLKAFTKAVEGAEDREELAEEDLKSIGLNEKDTVIGIAASGRTPYVIGGLKYANSVGAST
ASISCNKNAEISKYAKLNVEVETGAEILTGSTRLKAGTAQKLVLNMISTASMIGVGKVYKNLMVDVQSTNEKLVERSKRI
IVEATGVSYEVAAEHYEKAERNVKAAIVMVLLQCEYGEALEKLKQAKGFVKKAL

Sequences:

>Translated_294_residues
MLENLSTEHRNEKTMNLDEMNIKEVLQSMNEEDRTVALAVEKEIEHIEKVVRVVIQSFEEEGRLIYIGAGTSGRLGILDA
VECPPTFGTDDKMVQGFIAGGLKAFTKAVEGAEDREELAEEDLKSIGLNEKDTVIGIAASGRTPYVIGGLKYANSVGAST
ASISCNKNAEISKYAKLNVEVETGAEILTGSTRLKAGTAQKLVLNMISTASMIGVGKVYKNLMVDVQSTNEKLVERSKRI
IVEATGVSYEVAAEHYEKAERNVKAAIVMVLLQCEYGEALEKLKQAKGFVKKAL
>Mature_294_residues
MLENLSTEHRNEKTMNLDEMNIKEVLQSMNEEDRTVALAVEKEIEHIEKVVRVVIQSFEEEGRLIYIGAGTSGRLGILDA
VECPPTFGTDDKMVQGFIAGGLKAFTKAVEGAEDREELAEEDLKSIGLNEKDTVIGIAASGRTPYVIGGLKYANSVGAST
ASISCNKNAEISKYAKLNVEVETGAEILTGSTRLKAGTAQKLVLNMISTASMIGVGKVYKNLMVDVQSTNEKLVERSKRI
IVEATGVSYEVAAEHYEKAERNVKAAIVMVLLQCEYGEALEKLKQAKGFVKKAL

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI1788768, Length=293, Percent_Identity=50.8532423208191, Blast_Score=280, Evalue=1e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURQ_BACAA (C3P1J8)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002865404.1
- ProteinModelPortal:   C3P1J8
- SMR:   C3P1J8
- EnsemblBacteria:   EBBACT00000128044
- GeneID:   7852886
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_0931
- GeneTree:   EBGT00050000002902
- ProtClustDB:   PRK05441
- HAMAP:   MF_00068
- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347
- TIGRFAMs:   TIGR00274

Pfam domain/function: PF01380 SIS

EC number: NA

Molecular weight: Translated: 31979; Mature: 31979

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS01272 GCKR; PS51464 SIS

Important sites: ACT_SITE 82-82 ACT_SITE 113-113

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLENLSTEHRNEKTMNLDEMNIKEVLQSMNEEDRTVALAVEKEIEHIEKVVRVVIQSFEE
CCCCCCCHHCCCCCCCCCCCCHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
EGRLIYIGAGTSGRLGILDAVECPPTFGTDDKMVQGFIAGGLKAFTKAVEGAEDREELAE
CCCEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
EDLKSIGLNEKDTVIGIAASGRTPYVIGGLKYANSVGASTASISCNKNAEISKYAKLNVE
HHHHHCCCCCCCCEEEEEECCCCCEEEECHHHHHHCCCCCEEEECCCCCCCCEEEEEEEE
VETGAEILTGSTRLKAGTAQKLVLNMISTASMIGVGKVYKNLMVDVQSTNEKLVERSKRI
EECCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
IVEATGVSYEVAAEHYEKAERNVKAAIVMVLLQCEYGEALEKLKQAKGFVKKAL
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLENLSTEHRNEKTMNLDEMNIKEVLQSMNEEDRTVALAVEKEIEHIEKVVRVVIQSFEE
CCCCCCCHHCCCCCCCCCCCCHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
EGRLIYIGAGTSGRLGILDAVECPPTFGTDDKMVQGFIAGGLKAFTKAVEGAEDREELAE
CCCEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
EDLKSIGLNEKDTVIGIAASGRTPYVIGGLKYANSVGASTASISCNKNAEISKYAKLNVE
HHHHHCCCCCCCCEEEEEECCCCCEEEECHHHHHHCCCCCEEEECCCCCCCCEEEEEEEE
VETGAEILTGSTRLKAGTAQKLVLNMISTASMIGVGKVYKNLMVDVQSTNEKLVERSKRI
EECCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
IVEATGVSYEVAAEHYEKAERNVKAAIVMVLLQCEYGEALEKLKQAKGFVKKAL
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA