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The map label for this gene is yrbD [H]

Identifier: 49183630

GI number: 49183630

Start: 655727

End: 657187

Strand: Direct

Name: yrbD [H]

Synonym: BAS0605

Alternate gene names: 49183630

Gene position: 655727-657187 (Clockwise)

Preceding gene: 49183629

Following gene: 49183631

Centisome position: 12.54

GC content: 39.36

Gene sequence:

>1461_bases
TTGGAAGCTTTCGTAAATTGGTTAAATAATATTGTTTGGAGTCCAGCACTTGTTTATTTATGTTTAGGAGTAGGTTTATA
TTTTTCTATTCGAACGAGGTTTTTACAAGTAAGGCATGTAGGAGAAATGGTGAAGCTGACATTTCAAGGAGAAAAATCAG
AGGCTGGTGTTTCTTCATTCCAAGCGTTAGCACTTTCGTTATCAGGGCGCGTTGGGACAGGGAATATCGCTGGGGTAGCT
ACAGCGGTTGCCTTCGGTGGACCAGGGGCTGTATTTTGGATGTGGGCAGTAGCCTTTTTAGGAGCAGGATCAGCTTATGT
AGAATCAACACTCGCGCAAATATATAAGACGAAACATCAAGGACAGTTTCGCGGTGGACCTGCTTATTACATTGAAAAAG
GTTTAGGGGTTAAATGGTATGCTTTAGTATTCGTTGCAGCGACAATTCTTGCAACGGGGCTTTTACTACCAGGTGTGCAG
GCAAATAGTATTGCCGTAAGTTTAGAAACAGCCTTTGGAATTAACACTACTCTATCAGGGGCTTTATTAGTTGTTGTATT
AGCTCTTATCATCTTCGGTGGAGTAAAGCGAATTGTTAACGTGGCACAAGTTGTTGTACCGTTTATGGCAGTTGGGTATA
TTTTAGTAGCTTGCGTTATTGTTGCTATGAATATTGAAAAACTGCCAGAAGCATTTATGTTAATTATAAGAAGTGCTTTT
GCATTAGAAGCAGCATTTGGTGGTATTATCGGTTTAGCAATTTCTTGGGGAGTAAAACGTGGTATTTATTCTAATGAAGC
AGGGCAAGGAACTGGACCACATGCAGCAGCAGCAGCGGAAGTATCACATCCAGCTAAGCAAGGCTTAGTGCAAGCATTTT
CCGTTTACATTGATACATTATTTGTTTGTTCAGCAACAGCATTTATGATGATTATTACAGGCATGTATAACGTATTTGAT
GCAAGCGGAAAAAACTTTATCGTAAATAAATTAAATGGTGCACAGCCAGGACCAGGATATACACAGGCAGCAGTAGAATC
TGTTTTCCCTGGATTTGGAAACGGTTTCGTTGCAATCTCGTTACTATTCTTTGCATTTACAACAATTATGGCGTATTACT
ACATTGCAGAAACGAATATCGCGTACTTAAACCGTGATAAAGACCGCCCTTGGTTGTCTATGGTACTAAAATTTGTCTTT
TTAGGTGCTGTATTCTACGGCTGTATAAAAACAGCAGCAACGGCTTGGGCTTTAGGTGATATCGGTGTAGAAATTATGGC
ATGGGTAAATATCATTGCGATTTTATTGTTACAAAAACCTGCATTAGTTGCATTAAAGGATTATGAAAAGCAGAAGAAAG
AAGGAAAAGATCCAGTATTCGATCCAGGGCCATTAGGCATTAAAAATGCTGATTTCTGGGAGCATGAATACGGAAAAGGT
AAGAAAGAAGAAGTATCTTAA

Upstream 100 bases:

>100_bases
AAAATATGTTTGTTTTATTAAAATAATATTGTCATAGATTCGGTATACATTTATAATTTTTATATATTCTGAATATTCTT
TATAAAAAGGAGGGGGAATA

Downstream 100 bases:

>100_bases
TGGAATAGAAATGAAAAAGCAAAGGGAAAATCCCTTTGCTTTTTTTATGAGCAAAATGAAGCAGGCAGTTATTTTTTTGC
CTATTTTTGAATATAAAAAG

Product: sodium/alanine symporter family protein

Products: Na (I) [Cytoplasm]; L-alanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MEAFVNWLNNIVWSPALVYLCLGVGLYFSIRTRFLQVRHVGEMVKLTFQGEKSEAGVSSFQALALSLSGRVGTGNIAGVA
TAVAFGGPGAVFWMWAVAFLGAGSAYVESTLAQIYKTKHQGQFRGGPAYYIEKGLGVKWYALVFVAATILATGLLLPGVQ
ANSIAVSLETAFGINTTLSGALLVVVLALIIFGGVKRIVNVAQVVVPFMAVGYILVACVIVAMNIEKLPEAFMLIIRSAF
ALEAAFGGIIGLAISWGVKRGIYSNEAGQGTGPHAAAAAEVSHPAKQGLVQAFSVYIDTLFVCSATAFMMIITGMYNVFD
ASGKNFIVNKLNGAQPGPGYTQAAVESVFPGFGNGFVAISLLFFAFTTIMAYYYIAETNIAYLNRDKDRPWLSMVLKFVF
LGAVFYGCIKTAATAWALGDIGVEIMAWVNIIAILLLQKPALVALKDYEKQKKEGKDPVFDPGPLGIKNADFWEHEYGKG
KKEEVS

Sequences:

>Translated_486_residues
MEAFVNWLNNIVWSPALVYLCLGVGLYFSIRTRFLQVRHVGEMVKLTFQGEKSEAGVSSFQALALSLSGRVGTGNIAGVA
TAVAFGGPGAVFWMWAVAFLGAGSAYVESTLAQIYKTKHQGQFRGGPAYYIEKGLGVKWYALVFVAATILATGLLLPGVQ
ANSIAVSLETAFGINTTLSGALLVVVLALIIFGGVKRIVNVAQVVVPFMAVGYILVACVIVAMNIEKLPEAFMLIIRSAF
ALEAAFGGIIGLAISWGVKRGIYSNEAGQGTGPHAAAAAEVSHPAKQGLVQAFSVYIDTLFVCSATAFMMIITGMYNVFD
ASGKNFIVNKLNGAQPGPGYTQAAVESVFPGFGNGFVAISLLFFAFTTIMAYYYIAETNIAYLNRDKDRPWLSMVLKFVF
LGAVFYGCIKTAATAWALGDIGVEIMAWVNIIAILLLQKPALVALKDYEKQKKEGKDPVFDPGPLGIKNADFWEHEYGKG
KKEEVS
>Mature_486_residues
MEAFVNWLNNIVWSPALVYLCLGVGLYFSIRTRFLQVRHVGEMVKLTFQGEKSEAGVSSFQALALSLSGRVGTGNIAGVA
TAVAFGGPGAVFWMWAVAFLGAGSAYVESTLAQIYKTKHQGQFRGGPAYYIEKGLGVKWYALVFVAATILATGLLLPGVQ
ANSIAVSLETAFGINTTLSGALLVVVLALIIFGGVKRIVNVAQVVVPFMAVGYILVACVIVAMNIEKLPEAFMLIIRSAF
ALEAAFGGIIGLAISWGVKRGIYSNEAGQGTGPHAAAAAEVSHPAKQGLVQAFSVYIDTLFVCSATAFMMIITGMYNVFD
ASGKNFIVNKLNGAQPGPGYTQAAVESVFPGFGNGFVAISLLFFAFTTIMAYYYIAETNIAYLNRDKDRPWLSMVLKFVF
LGAVFYGCIKTAATAWALGDIGVEIMAWVNIIAILLLQKPALVALKDYEKQKKEGKDPVFDPGPLGIKNADFWEHEYGKG
KKEEVS

Specific function: Unknown

COG id: COG1115

COG function: function code E; Na+/alanine symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:alanine (SAF) symporter family [H]

Homologues:

Organism=Escherichia coli, GI1786188, Length=471, Percent_Identity=37.5796178343949, Blast_Score=288, Evalue=6e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001463 [H]

Pfam domain/function: PF01235 Na_Ala_symp [H]

EC number: NA

Molecular weight: Translated: 52058; Mature: 52058

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAFVNWLNNIVWSPALVYLCLGVGLYFSIRTRFLQVRHVGEMVKLTFQGEKSEAGVSSF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHH
QALALSLSGRVGTGNIAGVATAVAFGGPGAVFWMWAVAFLGAGSAYVESTLAQIYKTKHQ
HHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
GQFRGGPAYYIEKGLGVKWYALVFVAATILATGLLLPGVQANSIAVSLETAFGINTTLSG
CCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHCCCHHHHH
ALLVVVLALIIFGGVKRIVNVAQVVVPFMAVGYILVACVIVAMNIEKLPEAFMLIIRSAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALEAAFGGIIGLAISWGVKRGIYSNEAGQGTGPHAAAAAEVSHPAKQGLVQAFSVYIDTL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHH
FVCSATAFMMIITGMYNVFDASGKNFIVNKLNGAQPGPGYTQAAVESVFPGFGNGFVAIS
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCHHHHHH
LLFFAFTTIMAYYYIAETNIAYLNRDKDRPWLSMVLKFVFLGAVFYGCIKTAATAWALGD
HHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGVEIMAWVNIIAILLLQKPALVALKDYEKQKKEGKDPVFDPGPLGIKNADFWEHEYGKG
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCC
KKEEVS
CCCCCC
>Mature Secondary Structure
MEAFVNWLNNIVWSPALVYLCLGVGLYFSIRTRFLQVRHVGEMVKLTFQGEKSEAGVSSF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHH
QALALSLSGRVGTGNIAGVATAVAFGGPGAVFWMWAVAFLGAGSAYVESTLAQIYKTKHQ
HHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
GQFRGGPAYYIEKGLGVKWYALVFVAATILATGLLLPGVQANSIAVSLETAFGINTTLSG
CCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHCCCHHHHH
ALLVVVLALIIFGGVKRIVNVAQVVVPFMAVGYILVACVIVAMNIEKLPEAFMLIIRSAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALEAAFGGIIGLAISWGVKRGIYSNEAGQGTGPHAAAAAEVSHPAKQGLVQAFSVYIDTL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHH
FVCSATAFMMIITGMYNVFDASGKNFIVNKLNGAQPGPGYTQAAVESVFPGFGNGFVAIS
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCHHHHHH
LLFFAFTTIMAYYYIAETNIAYLNRDKDRPWLSMVLKFVFLGAVFYGCIKTAATAWALGD
HHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGVEIMAWVNIIAILLLQKPALVALKDYEKQKKEGKDPVFDPGPLGIKNADFWEHEYGKG
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCC
KKEEVS
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-alanine [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-alanine [Periplasm] = Na (I) [Cytoplasm] + L-alanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]