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The map label for this gene is treP [H]

Identifier: 49183623

GI number: 49183623

Start: 646910

End: 648337

Strand: Direct

Name: treP [H]

Synonym: BAS0598

Alternate gene names: 49183623

Gene position: 646910-648337 (Clockwise)

Preceding gene: 49183622

Following gene: 49183624

Centisome position: 12.37

GC content: 38.03

Gene sequence:

>1428_bases
ATGGGGAAAGACTATCGTAAAACAGCAGAGGAAGTGTTGCAGTATATTGGTGGGAAAGACAATATTGAACAAGCTGCGCA
CTGTGTAACGAGACTCCGTATCGCTTTAAAAGATGAAAGTAAAATAGATAACGATAAATTGCAGTCTGTTTCATTAGTAA
AGGGAGCGTTTCATAACGCTGGGGTATTTCAAATTGTAATTGGTCCAGGAGATGTTGATCGAGTATATGCTGAATTGATA
ACGCTTGCAGGTATGAAGGAAGCGACAGTAGCTGACGTAAAAGATTCCGGAAACCAAAAGTTAAATCCAGCTCAAAAGTT
TGTAAAAGTATTTTCAGATGTATTTATGCCGATATTACCAGCAATCGTAACAGCTGGTTTACTAATGGGTATTAACAATC
TATTAGGCGCAAAGGACTTATTTTTTGATGGGAAAAATTTATTAGATGTGTATCCAAACTTAAGTGGGCTTTGGGATTTA
ATTAATATGATGGCGAATACAGCATTCGTATTCTTACCGGCACTTGTCGGGTGGTCAGCAACGAAGCGTTTTGGTGGTAG
TCCAATACTAGGGATTGTTATGGGATTAATGCTTGTGCACCCAGCCTTATTAAATGCCTGGGACTATGGAAAAGCAGCGA
CTGGTTTAGATGGTCAAAAGATTGAGTACTTCAATATTTTAGGACTGTTCCAAATTGAGAAGGTAGGATATCAAGGTCAA
ATCTTGCCAGTTTTAGTAGCAGCATTTGTATTAAGTAAAGTGGAAATCTTCTTAAAGAAACATGTACCAAATGCAATTCA
ATTGTTAGTTGTACCCATTACAACGATTGTCGTAACAGGTGTGTTAGCATTAGGGATTATTGGTCCGGTTACACGTCATA
TTGGAGATTTATTAACAGCTGGATTAGTAGGTGTATATGAAACAGTACCAGTAGTTGGAGCAGTATTATTTGGAGCATTG
TATGCACCACTTGTAATTACAGGTATGCATCATATGTTTATTGCTATCGATTTACAATTAATTGCACAACACGGTGGTAC
ATTCATTTGGCCAATGATTGCTCTTTCTAACATTGCGCAAGGTAGTGCGGCACTTGCGATGTTCTGGATTTCTAAAAATC
AAAATGATAAAAGTATGGCATCGACATCAGCAATTTCGGCATATTTCGGTATTACAGAGCCAGCTATGTTTGGTGTGAAT
TTACGAAATAAATTCCCGTTCTATGCAGCGATTATAGGATCTGCTGTGGCGGCGATATTCATTACATTAAATGGTGTATT
AGCACCTGCTATCGGAATTGGCGGATTACCAGCATTTATTTCTATCATTCCGAAATCGATTCCAATGTTTATTGTAGGAA
TGGTTATCGCAGTTGTCATCCCATTCACGTTAACGTGGTTATTTGCAAAAAGAGTGAAACAGAAGTAG

Upstream 100 bases:

>100_bases
AAAAGTTACAAACTCGTATATACGAGTGTTGACTAACTTATATATACGAGTTAATATGTAATTGTAAACGGTATCAAAAA
AAGAAAAGAGGGACGGGAAT

Downstream 100 bases:

>100_bases
GAGGAAGTTAAACATGAAGGATTGGCATAAAAGTGTAGTTTATCAAATTTATCCGAAGAGCTTTAATAGCTATTACAATA
AAGAAACCGGTGATATAAAA

Product: PTS system trehalose-specific transporter subunit IIBC

Products: NA

Alternate protein names: EIIBC-Tre; EII-Tre; Trehalose-specific phosphotransferase enzyme IIB component; PTS system trehalose-specific EIIB component; Trehalose permease IIC component; PTS system trehalose-specific EIIC component [H]

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MGKDYRKTAEEVLQYIGGKDNIEQAAHCVTRLRIALKDESKIDNDKLQSVSLVKGAFHNAGVFQIVIGPGDVDRVYAELI
TLAGMKEATVADVKDSGNQKLNPAQKFVKVFSDVFMPILPAIVTAGLLMGINNLLGAKDLFFDGKNLLDVYPNLSGLWDL
INMMANTAFVFLPALVGWSATKRFGGSPILGIVMGLMLVHPALLNAWDYGKAATGLDGQKIEYFNILGLFQIEKVGYQGQ
ILPVLVAAFVLSKVEIFLKKHVPNAIQLLVVPITTIVVTGVLALGIIGPVTRHIGDLLTAGLVGVYETVPVVGAVLFGAL
YAPLVITGMHHMFIAIDLQLIAQHGGTFIWPMIALSNIAQGSAALAMFWISKNQNDKSMASTSAISAYFGITEPAMFGVN
LRNKFPFYAAIIGSAVAAIFITLNGVLAPAIGIGGLPAFISIIPKSIPMFIVGMVIAVVIPFTLTWLFAKRVKQK

Sequences:

>Translated_475_residues
MGKDYRKTAEEVLQYIGGKDNIEQAAHCVTRLRIALKDESKIDNDKLQSVSLVKGAFHNAGVFQIVIGPGDVDRVYAELI
TLAGMKEATVADVKDSGNQKLNPAQKFVKVFSDVFMPILPAIVTAGLLMGINNLLGAKDLFFDGKNLLDVYPNLSGLWDL
INMMANTAFVFLPALVGWSATKRFGGSPILGIVMGLMLVHPALLNAWDYGKAATGLDGQKIEYFNILGLFQIEKVGYQGQ
ILPVLVAAFVLSKVEIFLKKHVPNAIQLLVVPITTIVVTGVLALGIIGPVTRHIGDLLTAGLVGVYETVPVVGAVLFGAL
YAPLVITGMHHMFIAIDLQLIAQHGGTFIWPMIALSNIAQGSAALAMFWISKNQNDKSMASTSAISAYFGITEPAMFGVN
LRNKFPFYAAIIGSAVAAIFITLNGVLAPAIGIGGLPAFISIIPKSIPMFIVGMVIAVVIPFTLTWLFAKRVKQK
>Mature_474_residues
GKDYRKTAEEVLQYIGGKDNIEQAAHCVTRLRIALKDESKIDNDKLQSVSLVKGAFHNAGVFQIVIGPGDVDRVYAELIT
LAGMKEATVADVKDSGNQKLNPAQKFVKVFSDVFMPILPAIVTAGLLMGINNLLGAKDLFFDGKNLLDVYPNLSGLWDLI
NMMANTAFVFLPALVGWSATKRFGGSPILGIVMGLMLVHPALLNAWDYGKAATGLDGQKIEYFNILGLFQIEKVGYQGQI
LPVLVAAFVLSKVEIFLKKHVPNAIQLLVVPITTIVVTGVLALGIIGPVTRHIGDLLTAGLVGVYETVPVVGAVLFGALY
APLVITGMHHMFIAIDLQLIAQHGGTFIWPMIALSNIAQGSAALAMFWISKNQNDKSMASTSAISAYFGITEPAMFGVNL
RNKFPFYAAIIGSAVAAIFITLNGVLAPAIGIGGLPAFISIIPKSIPMFIVGMVIAVVIPFTLTWLFAKRVKQK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI2367362, Length=452, Percent_Identity=40.0442477876106, Blast_Score=345, Evalue=4e-96,
Organism=Escherichia coli, GI1790159, Length=474, Percent_Identity=29.1139240506329, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI48994906, Length=479, Percent_Identity=27.5574112734864, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1788769, Length=491, Percent_Identity=28.5132382892057, Blast_Score=151, Evalue=9e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011296 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 50964; Mature: 50833

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKDYRKTAEEVLQYIGGKDNIEQAAHCVTRLRIALKDESKIDNDKLQSVSLVKGAFHNA
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCC
GVFQIVIGPGDVDRVYAELITLAGMKEATVADVKDSGNQKLNPAQKFVKVFSDVFMPILP
CEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
AIVTAGLLMGINNLLGAKDLFFDGKNLLDVYPNLSGLWDLINMMANTAFVFLPALVGWSA
HHHHHHHHHHHHHHCCCHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
TKRFGGSPILGIVMGLMLVHPALLNAWDYGKAATGLDGQKIEYFNILGLFQIEKVGYQGQ
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCCC
ILPVLVAAFVLSKVEIFLKKHVPNAIQLLVVPITTIVVTGVLALGIIGPVTRHIGDLLTA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLVGVYETVPVVGAVLFGALYAPLVITGMHHMFIAIDLQLIAQHGGTFIWPMIALSNIAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
GSAALAMFWISKNQNDKSMASTSAISAYFGITEPAMFGVNLRNKFPFYAAIIGSAVAAIF
CCHHEEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHH
ITLNGVLAPAIGIGGLPAFISIIPKSIPMFIVGMVIAVVIPFTLTWLFAKRVKQK
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GKDYRKTAEEVLQYIGGKDNIEQAAHCVTRLRIALKDESKIDNDKLQSVSLVKGAFHNA
CCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCC
GVFQIVIGPGDVDRVYAELITLAGMKEATVADVKDSGNQKLNPAQKFVKVFSDVFMPILP
CEEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
AIVTAGLLMGINNLLGAKDLFFDGKNLLDVYPNLSGLWDLINMMANTAFVFLPALVGWSA
HHHHHHHHHHHHHHCCCHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
TKRFGGSPILGIVMGLMLVHPALLNAWDYGKAATGLDGQKIEYFNILGLFQIEKVGYQGQ
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCCC
ILPVLVAAFVLSKVEIFLKKHVPNAIQLLVVPITTIVVTGVLALGIIGPVTRHIGDLLTA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLVGVYETVPVVGAVLFGALYAPLVITGMHHMFIAIDLQLIAQHGGTFIWPMIALSNIAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
GSAALAMFWISKNQNDKSMASTSAISAYFGITEPAMFGVNLRNKFPFYAAIIGSAVAAIF
CCHHEEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHH
ITLNGVLAPAIGIGGLPAFISIIPKSIPMFIVGMVIAVVIPFTLTWLFAKRVKQK
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8917076; 8969503; 9272861; 9384377; 7651129 [H]