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The map label for this gene is mdmC [H]

Identifier: 46447465

GI number: 46447465

Start: 2186049

End: 2186726

Strand: Direct

Name: mdmC [H]

Synonym: pc1831

Alternate gene names: 46447465

Gene position: 2186049-2186726 (Clockwise)

Preceding gene: 46447464

Following gene: 46447466

Centisome position: 90.54

GC content: 38.35

Gene sequence:

>678_bases
ATGAATAAAAATCATCCAAATCCTGAAGAGTTAAGAGAGTATTTAGACAGACGGTTTGGACAAGAAGATGCGGTCTTACA
TCACATACGTCAAAACTCGGTTATTAAAGGCCTTCCTTCCATTCAAATTCCTATTTATCTAGGTAAGCTTCTTCATTTTT
TAGCCTCGACTCTGCAAGCTAAACATATTTTAGAGATTGGCACATTGGGTGGATATAGTACAGTTTGGTTAGCTCGAGCA
TTACCAGAAACAGGATATATGATTTCACTCGAAGCCAACCCCCAGTATTGCCAAATTGCCCAAGAACATCTCCATAAAGC
TGAGTTAAGTCACCTCGTTAAAATTCGGCAAGGCTATGCGGTAGATTTATTAGCTCAAATTGCAACGGAGAATTTAGCCT
CTTTCGACTTTGTATTCATTGATGCAGATAAAGAAAACAATGTCCTTTATTTAGATTGGGCTATTCATTTATCTCAACCT
GGTTCATTGATTTTAATTGATAATCTCATCCCGAAAGGTAAGCATGTCGGTTACCCAAATCACGAAGAAGCTCAAACCAT
TTATGCTTTTAATGATTATTTGGCTGTTCATCCAAAACTTGAAACAGTCCTCATTCCCACTCTTGTGCGAGAAGGAAGAT
TAGACGGTCTGGCTCTTGCTCGTGTCAAAAAGTCCTAA

Upstream 100 bases:

>100_bases
CCGTTTTAAATGGCATTGCTTACAATGAGTTAACCCGCACATTTTACTTAACTGGAAAATTATGGCCTTACTTATATGAA
GTTAAATTTGAGTCTGTTCC

Downstream 100 bases:

>100_bases
ACATTCTAATAATTACACTTCTTTTTTGGTGTGCTATTTAATAAAATTAATCTGAAATTTGGATTTTTAGGTAGCCTTTA
ATAATAGGCGATGTTGTTCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MNKNHPNPEELREYLDRRFGQEDAVLHHIRQNSVIKGLPSIQIPIYLGKLLHFLASTLQAKHILEIGTLGGYSTVWLARA
LPETGYMISLEANPQYCQIAQEHLHKAELSHLVKIRQGYAVDLLAQIATENLASFDFVFIDADKENNVLYLDWAIHLSQP
GSLILIDNLIPKGKHVGYPNHEEAQTIYAFNDYLAVHPKLETVLIPTLVREGRLDGLALARVKKS

Sequences:

>Translated_225_residues
MNKNHPNPEELREYLDRRFGQEDAVLHHIRQNSVIKGLPSIQIPIYLGKLLHFLASTLQAKHILEIGTLGGYSTVWLARA
LPETGYMISLEANPQYCQIAQEHLHKAELSHLVKIRQGYAVDLLAQIATENLASFDFVFIDADKENNVLYLDWAIHLSQP
GSLILIDNLIPKGKHVGYPNHEEAQTIYAFNDYLAVHPKLETVLIPTLVREGRLDGLALARVKKS
>Mature_225_residues
MNKNHPNPEELREYLDRRFGQEDAVLHHIRQNSVIKGLPSIQIPIYLGKLLHFLASTLQAKHILEIGTLGGYSTVWLARA
LPETGYMISLEANPQYCQIAQEHLHKAELSHLVKIRQGYAVDLLAQIATENLASFDFVFIDADKENNVLYLDWAIHLSQP
GSLILIDNLIPKGKHVGYPNHEEAQTIYAFNDYLAVHPKLETVLIPTLVREGRLDGLALARVKKS

Specific function: 4-O-methyltransferase for the lactone ring of midecamycin and other macrolide antibiotics [H]

COG id: COG4122

COG function: function code R; Predicted O-methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. Type 3 family [H]

Homologues:

Organism=Homo sapiens, GI31542747, Length=217, Percent_Identity=27.6497695852535, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002935 [H]

Pfam domain/function: PF01596 Methyltransf_3 [H]

EC number: NA

Molecular weight: Translated: 25414; Mature: 25414

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKNHPNPEELREYLDRRFGQEDAVLHHIRQNSVIKGLPSIQIPIYLGKLLHFLASTLQA
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCHHHCCCCCEEHHHHHHHHHHHHHHHHHH
KHILEIGTLGGYSTVWLARALPETGYMISLEANPQYCQIAQEHLHKAELSHLVKIRQGYA
HHHHHCCCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCH
VDLLAQIATENLASFDFVFIDADKENNVLYLDWAIHLSQPGSLILIDNLIPKGKHVGYPN
HHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEEEEEECCCCCEEEEECCCCCCCCCCCCC
HEEAQTIYAFNDYLAVHPKLETVLIPTLVREGRLDGLALARVKKS
CCCCEEEEEECCEEEECCCHHEEHHHHHHHCCCCCCHHHHEECCC
>Mature Secondary Structure
MNKNHPNPEELREYLDRRFGQEDAVLHHIRQNSVIKGLPSIQIPIYLGKLLHFLASTLQA
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCHHHCCCCCEEHHHHHHHHHHHHHHHHHH
KHILEIGTLGGYSTVWLARALPETGYMISLEANPQYCQIAQEHLHKAELSHLVKIRQGYA
HHHHHCCCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCH
VDLLAQIATENLASFDFVFIDADKENNVLYLDWAIHLSQPGSLILIDNLIPKGKHVGYPN
HHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEEEEEECCCCCEEEEECCCCCCCCCCCCC
HEEAQTIYAFNDYLAVHPKLETVLIPTLVREGRLDGLALARVKKS
CCCCEEEEEECCEEEECCCHHEEHHHHHHHCCCCCCHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1629172 [H]