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The map label for this gene is pgsA [H]

Identifier: 46447231

GI number: 46447231

Start: 1912196

End: 1912813

Strand: Direct

Name: pgsA [H]

Synonym: pc1597

Alternate gene names: 46447231

Gene position: 1912196-1912813 (Clockwise)

Preceding gene: 46447230

Following gene: 46447234

Centisome position: 79.2

GC content: 31.23

Gene sequence:

>618_bases
TTGAGTATTCCTAATTGTCTGACTTTTTTTCGTATTTTTATTAGCCCCATTTTTCTATTGGTTTATTTAGAATATGAGTT
TTTAAATATCCAAATGACAACTTTGCCTTATATTTTACTTTTTCTTTTAGGTATCTCAGAATTATCTGATGCCTGTGACG
GATATCTTGCACGTAAATATAATCAAGTTACAGATCTGGGTAAAATTTTAGATCCTATGGCAGACAGCATCTATAGAATT
TCAATTTTTCTAACTTTTACACTTCCTCCTGTTCAGCTTCCCATGCTTTTGATTTTTATTTTTATTTATAGAGATTCTGT
TGTAAGCACTTTAAGAACTATTTGTGCTTTGAAAGGATTCGCACTTGCTGCTAGACCTAGCGGTAAAATTAAAGCTGTCT
TTCAAGCCCTAGCTTCATTTACTGTCATTATTTTGCTAATTCCTTATTCGCTGGGTTATTTATCTCTTCATTCGCTACAA
TATATTAGCATGATAGTTGTATTAGCAGCCGCTCTTTATTCCTTACTTTCGGGTGTAGAATATGTTTATGCCAATAAACA
ATATATTATGAAGCTTTTGACATCTAAAAATAGCCTAAAACGAGATTTAATTGATTAA

Upstream 100 bases:

>100_bases
GGACTCTTGAATTAATACAAAAATGTAGTTATTCTTCCTTTCTCGTCTGAGTCTTGGATTTCTAATATAACTATCAGCGA
TGGTTGAAAGGAAGATTATC

Downstream 100 bases:

>100_bases
ATTTCGAAAAATTCCCTTTTTACAGTTGGTTTATAAACATTAAAAATGAATAGTTTATTCTGTTGAGAACAAAATACTCA
TCTAATTGGAATTCATCTCA

Product: putative phosphatidylglycerophosphate synthase (PGP synthase)

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MSIPNCLTFFRIFISPIFLLVYLEYEFLNIQMTTLPYILLFLLGISELSDACDGYLARKYNQVTDLGKILDPMADSIYRI
SIFLTFTLPPVQLPMLLIFIFIYRDSVVSTLRTICALKGFALAARPSGKIKAVFQALASFTVIILLIPYSLGYLSLHSLQ
YISMIVVLAAALYSLLSGVEYVYANKQYIMKLLTSKNSLKRDLID

Sequences:

>Translated_205_residues
MSIPNCLTFFRIFISPIFLLVYLEYEFLNIQMTTLPYILLFLLGISELSDACDGYLARKYNQVTDLGKILDPMADSIYRI
SIFLTFTLPPVQLPMLLIFIFIYRDSVVSTLRTICALKGFALAARPSGKIKAVFQALASFTVIILLIPYSLGYLSLHSLQ
YISMIVVLAAALYSLLSGVEYVYANKQYIMKLLTSKNSLKRDLID
>Mature_204_residues
SIPNCLTFFRIFISPIFLLVYLEYEFLNIQMTTLPYILLFLLGISELSDACDGYLARKYNQVTDLGKILDPMADSIYRIS
IFLTFTLPPVQLPMLLIFIFIYRDSVVSTLRTICALKGFALAARPSGKIKAVFQALASFTVIILLIPYSLGYLSLHSLQY
ISMIVVLAAALYSLLSGVEYVYANKQYIMKLLTSKNSLKRDLID

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=199, Percent_Identity=27.1356783919598, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 23200; Mature: 23069

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIPNCLTFFRIFISPIFLLVYLEYEFLNIQMTTLPYILLFLLGISELSDACDGYLARKY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NQVTDLGKILDPMADSIYRISIFLTFTLPPVQLPMLLIFIFIYRDSVVSTLRTICALKGF
HHHHHHHHHHHHHHHHHEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ALAARPSGKIKAVFQALASFTVIILLIPYSLGYLSLHSLQYISMIVVLAAALYSLLSGVE
CEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
YVYANKQYIMKLLTSKNSLKRDLID
HHHCCHHHHHHHHHCCHHHHHHCCC
>Mature Secondary Structure 
SIPNCLTFFRIFISPIFLLVYLEYEFLNIQMTTLPYILLFLLGISELSDACDGYLARKY
CCCHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NQVTDLGKILDPMADSIYRISIFLTFTLPPVQLPMLLIFIFIYRDSVVSTLRTICALKGF
HHHHHHHHHHHHHHHHHEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ALAARPSGKIKAVFQALASFTVIILLIPYSLGYLSLHSLQYISMIVVLAAALYSLLSGVE
CEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
YVYANKQYIMKLLTSKNSLKRDLID
HHHCCHHHHHHHHHCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA