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The map label for this gene is sctN [H]

Identifier: 46447031

GI number: 46447031

Start: 1673399

End: 1674763

Strand: Direct

Name: sctN [H]

Synonym: pc1397

Alternate gene names: 46447031

Gene position: 1673399-1674763 (Clockwise)

Preceding gene: 46447030

Following gene: 46447032

Centisome position: 69.31

GC content: 40.59

Gene sequence:

>1365_bases
TTGTCCTTATTTTCTATCTACTATTGTTTCCAACTAAGGGTAAATTTCATGTTTTTTAATGATCAAATTGACAAACTTCT
GGATGATCTAGATGAACTTCAACTTACGACGGTGAATGGCCGCATTACCGAAATTGTTGGAATGTTAATCAAAGCTGTGG
TGCCTCAAGTAAAAATTGGGGAAGTTTGTTTAATCAAAAGAGCAGGTGACCCTTTACGCGCAGAAGTGGTGGGTTTTACA
AAAGACGAAGTCCTTCTTTCTCCTTTAGGAGAAATGACTGGTATCGGCCCCTCTTCTGAAGTCATTCCCACTCATCTTCC
TTTACACATCAAAGTCGGCCCTCAATTGCTTGGGAGAATTTTAAATGGTTTAGGAGAACCCTTAGACGAAGAAACCAAAG
GTCCTTTAATCTTAGAAGAGACCTATCCTGTTATTCAAGCTCCTCCTGACCCTGTCAAAAGAATGCCTATTCATAACCCT
ATTTCCGTTGGAATAAGGGCTATTGACGGCGTATTAACTACAGGCCTCGGACAAAGAGTAGGGATTTTTGCTGCTGCAGG
TGGTGGTAAATCAACATTACTTGGAATGATTGCTCGCAATGCAGTCGCAGATGTCAATGTAATCAGTTTAATTGGGGAGC
GAGGGCGAGAACTCAGAGAATTTATTGAAAAGGATTTAGGTCCCGAAGGACTAAAAAGATCTGTCCTTGTGGTCTCGACC
TCTGACCAAGCCTCCCAGCTTCGTCTCAATGCAGCTTACGTTGGTACTGCGATTGCTGAATATTTTAGAGATCAAGGTAA
ATCTGTCATCTTAATGATGGATTCGGTGACGAGATTTGCAAGAGCTCTGCGTGAAGTAGGCTTAGCAGCAGGCGAACCTC
CGGCAAGAGCTGGTTATACTCCTTCAGTCTTTTCAACGCTTCCTAAACTATTGGAAAGAGCGGGAAATTCTGATAAAGGG
AGTATTACAGCTTTTTATACTATCTTAGTGGCTGGAGATGATATGAATGAACCCGTTGCTGATGAAGTACGCTCTATTCT
GGATGGTCACATTATTTTATCTAGTGAACTTGCACGTCAATATCATTATCCCGCCATTGATGTTCTCTCCTCTGCAAGTC
GTGTCATGAATGCCATTGTTCCCAAAGAACACTTGCAATTAGTTGGTAAACTTAAAGAAGTTTTAGCTAATTATAAAAAA
AACGAGCTATTAATTAAAATTGGCGAATACAAAAGAGGGGCGGATAAAGCAGGAGATTTTGCCATAGACTATATCGAAAA
AGTTTTAAAATTTCTCAAACAAGGTGTCGACGAAAAATGCTCATTTCAAGAGACTGTCCAACTCCTGAAATCTCTCTTCA
GATAA

Upstream 100 bases:

>100_bases
AGCTTTAGAATCGACAAAAACAATCATGAACGTTCAAGTCTAAAGCAAAAAAAATATTGGTTGGTTTCTTCATTCTTGAT
ATCTTAATATAAGGAATATT

Downstream 100 bases:

>100_bases
AATTGGTTAAATTATGAGCAAAATCGTTTATCCTTTAAAACAAGTCATTGAAGTTAAACAAAGGCGCGTTGAAGAAGCCG
AGAAAAATGTTAAACAAAAG

Product: type III secretion system ATPase

Products: NA

Alternate protein names: Yop proteins secretion ATPase [H]

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MSLFSIYYCFQLRVNFMFFNDQIDKLLDDLDELQLTTVNGRITEIVGMLIKAVVPQVKIGEVCLIKRAGDPLRAEVVGFT
KDEVLLSPLGEMTGIGPSSEVIPTHLPLHIKVGPQLLGRILNGLGEPLDEETKGPLILEETYPVIQAPPDPVKRMPIHNP
ISVGIRAIDGVLTTGLGQRVGIFAAAGGGKSTLLGMIARNAVADVNVISLIGERGRELREFIEKDLGPEGLKRSVLVVST
SDQASQLRLNAAYVGTAIAEYFRDQGKSVILMMDSVTRFARALREVGLAAGEPPARAGYTPSVFSTLPKLLERAGNSDKG
SITAFYTILVAGDDMNEPVADEVRSILDGHIILSSELARQYHYPAIDVLSSASRVMNAIVPKEHLQLVGKLKEVLANYKK
NELLIKIGEYKRGADKAGDFAIDYIEKVLKFLKQGVDEKCSFQETVQLLKSLFR

Sequences:

>Translated_454_residues
MSLFSIYYCFQLRVNFMFFNDQIDKLLDDLDELQLTTVNGRITEIVGMLIKAVVPQVKIGEVCLIKRAGDPLRAEVVGFT
KDEVLLSPLGEMTGIGPSSEVIPTHLPLHIKVGPQLLGRILNGLGEPLDEETKGPLILEETYPVIQAPPDPVKRMPIHNP
ISVGIRAIDGVLTTGLGQRVGIFAAAGGGKSTLLGMIARNAVADVNVISLIGERGRELREFIEKDLGPEGLKRSVLVVST
SDQASQLRLNAAYVGTAIAEYFRDQGKSVILMMDSVTRFARALREVGLAAGEPPARAGYTPSVFSTLPKLLERAGNSDKG
SITAFYTILVAGDDMNEPVADEVRSILDGHIILSSELARQYHYPAIDVLSSASRVMNAIVPKEHLQLVGKLKEVLANYKK
NELLIKIGEYKRGADKAGDFAIDYIEKVLKFLKQGVDEKCSFQETVQLLKSLFR
>Mature_453_residues
SLFSIYYCFQLRVNFMFFNDQIDKLLDDLDELQLTTVNGRITEIVGMLIKAVVPQVKIGEVCLIKRAGDPLRAEVVGFTK
DEVLLSPLGEMTGIGPSSEVIPTHLPLHIKVGPQLLGRILNGLGEPLDEETKGPLILEETYPVIQAPPDPVKRMPIHNPI
SVGIRAIDGVLTTGLGQRVGIFAAAGGGKSTLLGMIARNAVADVNVISLIGERGRELREFIEKDLGPEGLKRSVLVVSTS
DQASQLRLNAAYVGTAIAEYFRDQGKSVILMMDSVTRFARALREVGLAAGEPPARAGYTPSVFSTLPKLLERAGNSDKGS
ITAFYTILVAGDDMNEPVADEVRSILDGHIILSSELARQYHYPAIDVLSSASRVMNAIVPKEHLQLVGKLKEVLANYKKN
ELLIKIGEYKRGADKAGDFAIDYIEKVLKFLKQGVDEKCSFQETVQLLKSLFR

Specific function: Is a component of the Yop secretion machinery using ATP, and it is either the energizer of this machinery, or part of it [H]

COG id: COG1157

COG function: function code NU; Flagellar biosynthesis/type III secretory pathway ATPase

Gene ontology:

Cell location: Cytoplasm. Note=But connected to the inner membrane possibly through LcrD (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=350, Percent_Identity=32, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI50345984, Length=361, Percent_Identity=28.2548476454294, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI4757810, Length=361, Percent_Identity=28.2548476454294, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI19913424, Length=352, Percent_Identity=29.5454545454545, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI19913428, Length=372, Percent_Identity=27.1505376344086, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI19913426, Length=372, Percent_Identity=27.6881720430108, Blast_Score=113, Evalue=4e-25,
Organism=Escherichia coli, GI1788251, Length=427, Percent_Identity=43.7939110070258, Blast_Score=341, Evalue=5e-95,
Organism=Escherichia coli, GI1790170, Length=407, Percent_Identity=27.5184275184275, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1790172, Length=371, Percent_Identity=29.1105121293801, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1790217, Length=240, Percent_Identity=28.3333333333333, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25144756, Length=350, Percent_Identity=32.8571428571429, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71988080, Length=315, Percent_Identity=29.5238095238095, Blast_Score=131, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI71988063, Length=315, Percent_Identity=29.5238095238095, Blast_Score=131, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI17565854, Length=403, Percent_Identity=28.5359801488834, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71988074, Length=299, Percent_Identity=29.0969899665552, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17510931, Length=364, Percent_Identity=27.7472527472527, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17570191, Length=370, Percent_Identity=27.2972972972973, Blast_Score=112, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6322581, Length=418, Percent_Identity=29.1866028708134, Blast_Score=160, Evalue=5e-40,
Organism=Saccharomyces cerevisiae, GI6319370, Length=354, Percent_Identity=30.5084745762712, Blast_Score=144, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6319603, Length=374, Percent_Identity=28.6096256684492, Blast_Score=120, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6320016, Length=228, Percent_Identity=32.4561403508772, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24638766, Length=357, Percent_Identity=31.6526610644258, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24658560, Length=342, Percent_Identity=29.5321637426901, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28574560, Length=319, Percent_Identity=30.7210031347962, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24583992, Length=344, Percent_Identity=29.9418604651163, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24583988, Length=344, Percent_Identity=31.1046511627907, Blast_Score=128, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24583986, Length=344, Percent_Identity=31.1046511627907, Blast_Score=128, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24583984, Length=344, Percent_Identity=31.1046511627907, Blast_Score=128, Evalue=7e-30,
Organism=Drosophila melanogaster, GI20129479, Length=354, Percent_Identity=29.6610169491525, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI281361666, Length=374, Percent_Identity=28.0748663101604, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24646341, Length=374, Percent_Identity=28.0748663101604, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI17136796, Length=374, Percent_Identity=28.0748663101604, Blast_Score=115, Evalue=7e-26,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR004100
- InterPro:   IPR005714
- InterPro:   IPR013380 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 49594; Mature: 49463

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFSIYYCFQLRVNFMFFNDQIDKLLDDLDELQLTTVNGRITEIVGMLIKAVVPQVKIG
CCHHHHHHEEEHEEEEEEECHHHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHCCCCCCC
EVCLIKRAGDPLRAEVVGFTKDEVLLSPLGEMTGIGPSSEVIPTHLPLHIKVGPQLLGRI
CEEEEECCCCCCEEHEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECHHHHHHH
LNGLGEPLDEETKGPLILEETYPVIQAPPDPVKRMPIHNPISVGIRAIDGVLTTGLGQRV
HHHHCCCCCCCCCCCEEEECCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHCCCCCC
GIFAAAGGGKSTLLGMIARNAVADVNVISLIGERGRELREFIEKDLGPEGLKRSVLVVST
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEEEC
SDQASQLRLNAAYVGTAIAEYFRDQGKSVILMMDSVTRFARALREVGLAAGEPPARAGYT
CCCHHHHEEHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCC
PSVFSTLPKLLERAGNSDKGSITAFYTILVAGDDMNEPVADEVRSILDGHIILSSELARQ
HHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHCCCEEEHHHHHHH
YHYPAIDVLSSASRVMNAIVPKEHLQLVGKLKEVLANYKKNELLIKIGEYKRGADKAGDF
HCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCH
AIDYIEKVLKFLKQGVDEKCSFQETVQLLKSLFR
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SLFSIYYCFQLRVNFMFFNDQIDKLLDDLDELQLTTVNGRITEIVGMLIKAVVPQVKIG
CHHHHHHEEEHEEEEEEECHHHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHCCCCCCC
EVCLIKRAGDPLRAEVVGFTKDEVLLSPLGEMTGIGPSSEVIPTHLPLHIKVGPQLLGRI
CEEEEECCCCCCEEHEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECHHHHHHH
LNGLGEPLDEETKGPLILEETYPVIQAPPDPVKRMPIHNPISVGIRAIDGVLTTGLGQRV
HHHHCCCCCCCCCCCEEEECCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHCCCCCC
GIFAAAGGGKSTLLGMIARNAVADVNVISLIGERGRELREFIEKDLGPEGLKRSVLVVST
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEEEC
SDQASQLRLNAAYVGTAIAEYFRDQGKSVILMMDSVTRFARALREVGLAAGEPPARAGYT
CCCHHHHEEHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCC
PSVFSTLPKLLERAGNSDKGSITAFYTILVAGDDMNEPVADEVRSILDGHIILSSELARQ
HHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHCCCEEEHHHHHHH
YHYPAIDVLSSASRVMNAIVPKEHLQLVGKLKEVLANYKKNELLIKIGEYKRGADKAGDF
HCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCH
AIDYIEKVLKFLKQGVDEKCSFQETVQLLKSLFR
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8132449; 2160939 [H]