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The map label for this gene is topI

Identifier: 46446816

GI number: 46446816

Start: 1410213

End: 1411289

Strand: Direct

Name: topI

Synonym: pc1182

Alternate gene names: NA

Gene position: 1410213-1411289 (Clockwise)

Preceding gene: 46446815

Following gene: 46446819

Centisome position: 58.41

GC content: 35.75

Gene sequence:

>1077_bases
ATGAAGAAAATTAAAATAAAGCCCGAAGCTTGCACAGAAATTGATCCGAAAAAATTAGCTGAAGTCGCTAATTTAACTTA
CGTGAACAATTTCAAACATGGAATTACGCGAGAGCGTAAAGGCAAACAGTTTATATATAAAGATAGCAATGGCAAAATTA
TTATCGATTCTAATGAAATTAAACGTATTCAAGCTTTAGCTATTCCTCCTGCCTATACAGATGTTTGGATCTGTCCGAGT
CTTAATGGTCATATTCAAGCTACCGGACGGGATGCGAAGGGTCGTAAACAATACCGTTACCATGCACTTTGGAAAGAAGT
TAGCGATGAAACCAAATATGGCAAGATGATCGCTTTTGCTCAAGCACTCCCTACAATCAGAAAACGAATCAAACGAGATT
TATCTTTAACCGAGATGTCAAAAGAAAAAATTTTGGCTGTAGTCGTTTATTTATTAGAAATGACGCTCATCCGTGTAGGA
AATGAAGCATATGCAAAAGAAAATAATTCTTTTGGATTAACAACCCTACAAAATCATCATGTTTCGATTGAAGGAACTGA
AATGACTTTTAAATTTATTGGTAAAAGCGGAAAGCAGCATACCATCACTCTATACGATAAACGTCTAGCAAAAATTGTCA
AGCGTTGTAAAGATTTGCCAGGACAAGAGCTTTTTGAATACATGGATGAAAATGCCATGCCTGTATCAATCAGTTCTACA
AATGTTAATGAATATTTACGTATGATCACAAACGATCATTTTACAGCTAAAGATTTTCGTACATGGGCAGGAACAGTGTT
GACTGTCTTTGCTTTGCAAGAATTCGAACACTTTGACTCACATGCGCAAGCAAAGCGTAACATTGTCCAAGCCATAGAAA
AAGTGGCTAAAAAGTTAGGCAATACCCCAGCCATTTGCCGCAAAAGTTATGTCCATCCAGAAGTCTTTAATGCTTACTTA
GATCAAACTTTATTTAAGGTGACAAAGCGCCCAAGCAAAAAATCTGTAGATTTAGTCATGGAACTTAGTTTTGAAGAAAC
GTATGTTCTCAATTTTTTAAAAAAGCGAATGAAATGA

Upstream 100 bases:

>100_bases
AGATATCTTATCATTTTTATCTCCCTACTAAAGCAACTCAAATCCAAATTTTTTATAGGGCAGGATAAGCGATGGTTTAG
CAACTAAAATTAAATTTACG

Downstream 100 bases:

>100_bases
GAAATTTCAAAGAAAATTCTAAATTATCGAGATTAAATAACAAAATTTTTTGCTTGAAATTTACCTATGAGGCAAAAATT
TTGTAAGCGCAAGAATTTGC

Product: putative DNA topoisomerase I

Products: NA

Alternate protein names: DNA poisomerase I; DNA poisomerase Type I; DNA poisomerase IB; Type I poisomerase; DNA poisomerase I Protein; Poisomerase IB; Poisomerase IB-Like Protein; DNA poisomerase I-Like Protein; Viral-Like DNA poisomerase; DNA poisomerase ; Eukaryotic-Like DNA poisomerase I; DNA poisomerasei; -Like DNA poisomerase I; Type I DNA poisomerase

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MKKIKIKPEACTEIDPKKLAEVANLTYVNNFKHGITRERKGKQFIYKDSNGKIIIDSNEIKRIQALAIPPAYTDVWICPS
LNGHIQATGRDAKGRKQYRYHALWKEVSDETKYGKMIAFAQALPTIRKRIKRDLSLTEMSKEKILAVVVYLLEMTLIRVG
NEAYAKENNSFGLTTLQNHHVSIEGTEMTFKFIGKSGKQHTITLYDKRLAKIVKRCKDLPGQELFEYMDENAMPVSISST
NVNEYLRMITNDHFTAKDFRTWAGTVLTVFALQEFEHFDSHAQAKRNIVQAIEKVAKKLGNTPAICRKSYVHPEVFNAYL
DQTLFKVTKRPSKKSVDLVMELSFEETYVLNFLKKRMK

Sequences:

>Translated_358_residues
MKKIKIKPEACTEIDPKKLAEVANLTYVNNFKHGITRERKGKQFIYKDSNGKIIIDSNEIKRIQALAIPPAYTDVWICPS
LNGHIQATGRDAKGRKQYRYHALWKEVSDETKYGKMIAFAQALPTIRKRIKRDLSLTEMSKEKILAVVVYLLEMTLIRVG
NEAYAKENNSFGLTTLQNHHVSIEGTEMTFKFIGKSGKQHTITLYDKRLAKIVKRCKDLPGQELFEYMDENAMPVSISST
NVNEYLRMITNDHFTAKDFRTWAGTVLTVFALQEFEHFDSHAQAKRNIVQAIEKVAKKLGNTPAICRKSYVHPEVFNAYL
DQTLFKVTKRPSKKSVDLVMELSFEETYVLNFLKKRMK
>Mature_358_residues
MKKIKIKPEACTEIDPKKLAEVANLTYVNNFKHGITRERKGKQFIYKDSNGKIIIDSNEIKRIQALAIPPAYTDVWICPS
LNGHIQATGRDAKGRKQYRYHALWKEVSDETKYGKMIAFAQALPTIRKRIKRDLSLTEMSKEKILAVVVYLLEMTLIRVG
NEAYAKENNSFGLTTLQNHHVSIEGTEMTFKFIGKSGKQHTITLYDKRLAKIVKRCKDLPGQELFEYMDENAMPVSISST
NVNEYLRMITNDHFTAKDFRTWAGTVLTVFALQEFEHFDSHAQAKRNIVQAIEKVAKKLGNTPAICRKSYVHPEVFNAYL
DQTLFKVTKRPSKKSVDLVMELSFEETYVLNFLKKRMK

Specific function: Unknown

COG id: COG3569

COG function: function code L; Topoisomerase IB

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 41237; Mature: 41237

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIKIKPEACTEIDPKKLAEVANLTYVNNFKHGITRERKGKQFIYKDSNGKIIIDSNEI
CCCEECCCHHCCCCCHHHHHHHHHHHHHHCHHHCCCCCCCCCEEEEECCCCEEEEECCHH
KRIQALAIPPAYTDVWICPSLNGHIQATGRDAKGRKQYRYHALWKEVSDETKYGKMIAFA
HEEEEEECCCCCCCEEEECCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
QALPTIRKRIKRDLSLTEMSKEKILAVVVYLLEMTLIRVGNEAYAKENNSFGLTTLQNHH
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEECCE
VSIEGTEMTFKFIGKSGKQHTITLYDKRLAKIVKRCKDLPGQELFEYMDENAMPVSISST
EEEECCEEEEEEECCCCCCEEEEHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEECC
NVNEYLRMITNDHFTAKDFRTWAGTVLTVFALQEFEHFDSHAQAKRNIVQAIEKVAKKLG
CHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NTPAICRKSYVHPEVFNAYLDQTLFKVTKRPSKKSVDLVMELSFEETYVLNFLKKRMK
CCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKKIKIKPEACTEIDPKKLAEVANLTYVNNFKHGITRERKGKQFIYKDSNGKIIIDSNEI
CCCEECCCHHCCCCCHHHHHHHHHHHHHHCHHHCCCCCCCCCEEEEECCCCEEEEECCHH
KRIQALAIPPAYTDVWICPSLNGHIQATGRDAKGRKQYRYHALWKEVSDETKYGKMIAFA
HEEEEEECCCCCCCEEEECCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
QALPTIRKRIKRDLSLTEMSKEKILAVVVYLLEMTLIRVGNEAYAKENNSFGLTTLQNHH
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEECCE
VSIEGTEMTFKFIGKSGKQHTITLYDKRLAKIVKRCKDLPGQELFEYMDENAMPVSISST
EEEECCEEEEEEECCCCCCEEEEHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEECC
NVNEYLRMITNDHFTAKDFRTWAGTVLTVFALQEFEHFDSHAQAKRNIVQAIEKVAKKLG
CHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NTPAICRKSYVHPEVFNAYLDQTLFKVTKRPSKKSVDLVMELSFEETYVLNFLKKRMK
CCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA