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The map label for this gene is lhr [C]

Identifier: 46446583

GI number: 46446583

Start: 1145530

End: 1147944

Strand: Reverse

Name: lhr [C]

Synonym: pc0949

Alternate gene names: 46446583

Gene position: 1147944-1145530 (Counterclockwise)

Preceding gene: 46446584

Following gene: 46446582

Centisome position: 47.54

GC content: 35.32

Gene sequence:

>2415_bases
ATGACTCTTCCTAAGCATTCACTCATTGAACAATGGTTTAATTTTAAAAAATGGGAACCTCTTCCCTTTCAAAAAGAAGC
CTGGTTAAAATTTTTAGAAGGAAAAAGTGGGTTAATTTCTGTTCCGACAGGGGCTGGTAAAACATATGCTGCTTATCTTT
CAGCTCTTTCTAAGCTTCATGAAGATCCCAAAAAAGGAATTCAAATCTTATACATCACTCCTTTAAGGGCTTTAGCAAAA
GATTTGGAAAGCGCTCTTAAAGCTCCTATTGATGATTTAAAATTGATTTACCGCGTCGAAAGGCGCACAGGAGATACTTC
CTATATAAAAAAAGAAAAGCAGAATAAACATCCCCCAGAAATTTTGATTACGACTCCTGAGAGTTTGGCTGTGATGCTTT
GCAATGGTCACGCAACTTCTCAATTTAGCTATCTACAGTCCATTATTGTCGATGAATGGCATGAGCTGTTAGCTTCTAAA
AGAGGCGTCTTGTTTGAGCTTTGTCTATCTCGATTAAAAGCTTGGAAACCTTCCGTACAAATTTGGGGATTAACCGCGAC
AATTGGCAATATTCAGCAAGCTGCACAAGTTTGTGTAGGAGTTGATCGCAGTCCCATCATTGTAAATGCAAAAATGGAAC
GAGAAGTCATCTTAACGGCTGTATTGCCAGAATCTTTGGATAAGCTCCCGTGGACAGGAAGATTGGGTTTACGATTACTC
CCTTACGTTCTAAATCGACTAAACTTCAATCAATCTACTCTTATTTTTACTAATACACGCTCGCAAACAGAAAGATGGTA
TCAAGCGATATTAGAGGCGAGGCCTGAATGGAAAAACTTAATAGCCATTCATCATAGTGCCATCGATAAAAAAACAAGGG
AAGGAATAGAAGAGGGGATTAAATTTGGTTCGATTCGTTTTGTTGTTTGCACCTCTTCTTTAGATTTAGGAATCGATTTA
CCAAGGGTTGAAAAAGTCATTCAAATTGGCTCCCCTAAAAGTGTTGCACGGCTTCTTCAAAGAGCTGGGCGCTCTTCTCA
TCGCCCTCTTACGCCTTGTTACATTGAAGTTGTTCCTACACATGCCCTAGAATTAATCGAAATTCAAGCTTATCGACTAG
CTATTAAAGAACATCATATTGAAAGCCGTTTGCCTTTAAAAAATTGCTATGATGTTTTAATGCAGCACATGATGACATGT
GCAATTGGAGAAGGTTTTCAAAAAGATGAACTTTTTTCTCAGATAAAAACAACAGCTTGTTTTCAAGATTTGAGTTTGAA
AGATTTTGAAGATTGCTTGCATTTTTTAATTTCGGGAGGAAATTCTTTAAAAGCTTACCCTGAATATAAAAAGCTAGTTT
ATTCAAATGACAAATACATTGTTGAAGATAAAGGATTGATTCGTCGGCATAAAATGAGTATCGGAACCATTTCTTCTGAT
TCTCAAATTACCGTTAAATGGACCAAAGGAAAAGCGATTGGAATGATAGAAGAATCTTTTTTGACGAATTTAAAACCTGG
AGATCATTTTCTTTTTGGGGGAAAACAATTACAGTTAGTTCAATATCGAGACATGACAGCTTATGTTCGTTTAGCCAAAC
ATAAGCAAAAACATGCAGCCGTTTGGAGAGGAAGCCATCTTCCTTTTTCAGCGTCTTTAGGAGTAGAGCTAAGAAAAGTA
TGTGAGCAAAAAATATCGCTTAACTCGTCCGACCAAGAAAAATTTCTTTTAGATCAAATCATTCAATTACAACAAAAATT
TTCGTATCTTCCTACGACAAAACAGCTTTTGATTGAATTAACAAAGTCTCAGGAAGGATGGCATCTTTTTGTTTATCCTT
TTGAAGGTAAAATTATCCATCAAGGTCTTGCTTTGTTAGTTGCTCATCGTTTATCAAAAAAAGCGTCTCAAACTTTTACA
ATAAGTACAAATGATTATGGATTTGAATTGCTGAGCCGGAAGTCTTTCCAGGAGGAAATGCTAACAACGGAACTTTTTTC
AACTCAATATATGAATGAAGACATCCAGGAATTGATTAATACTCAAGAAATTGGAAAAAGGTATTTTAGAGATATTGCTA
GAATTGCAGGATTAATCTTTCCAGGTTATCCACACAAACATAAAACAAATAGACAAGTACAAATCAGCAGTAGCCTTTTA
TTTGATGTTTTACAAAAATATGACGCAAATAATTTGCTGCTACAGCAAGCTAAAAAGGAAGTATTAGATATTCAATTTGA
AAAAATTCAGCTAAAAAATTGTTTAACACGTTTATCTCAAGCTCAATTAATGATAAAAAAACTCAAAAAATTTAGCCCCT
TTGGATTGGAGTTATTTGTAGAACGCGTTAATGACACTTTATCTACAGAAAGCTTAACAGAGCGAATTAAGCAAATTCAA
AATAGTTGGTTCTGA

Upstream 100 bases:

>100_bases
TCAGGAATAGCTCTACGATTTCCTCGCATCAAAAGATGGAGAACTGATAAACCTTATCAAGAATGCGATGATTTAGAAAC
AATTATAAAAACGTTTTTAC

Downstream 100 bases:

>100_bases
TGAAATGCCTCATTGAAAATCAAACATGTCATTTTTTGCCTCAAAGAGGAGTTTATTGGGAAGAACAAAAAACGTTGATA
ATCGCGGATGTTCATTTGGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 804; Mature: 803

Protein sequence:

>804_residues
MTLPKHSLIEQWFNFKKWEPLPFQKEAWLKFLEGKSGLISVPTGAGKTYAAYLSALSKLHEDPKKGIQILYITPLRALAK
DLESALKAPIDDLKLIYRVERRTGDTSYIKKEKQNKHPPEILITTPESLAVMLCNGHATSQFSYLQSIIVDEWHELLASK
RGVLFELCLSRLKAWKPSVQIWGLTATIGNIQQAAQVCVGVDRSPIIVNAKMEREVILTAVLPESLDKLPWTGRLGLRLL
PYVLNRLNFNQSTLIFTNTRSQTERWYQAILEARPEWKNLIAIHHSAIDKKTREGIEEGIKFGSIRFVVCTSSLDLGIDL
PRVEKVIQIGSPKSVARLLQRAGRSSHRPLTPCYIEVVPTHALELIEIQAYRLAIKEHHIESRLPLKNCYDVLMQHMMTC
AIGEGFQKDELFSQIKTTACFQDLSLKDFEDCLHFLISGGNSLKAYPEYKKLVYSNDKYIVEDKGLIRRHKMSIGTISSD
SQITVKWTKGKAIGMIEESFLTNLKPGDHFLFGGKQLQLVQYRDMTAYVRLAKHKQKHAAVWRGSHLPFSASLGVELRKV
CEQKISLNSSDQEKFLLDQIIQLQQKFSYLPTTKQLLIELTKSQEGWHLFVYPFEGKIIHQGLALLVAHRLSKKASQTFT
ISTNDYGFELLSRKSFQEEMLTTELFSTQYMNEDIQELINTQEIGKRYFRDIARIAGLIFPGYPHKHKTNRQVQISSSLL
FDVLQKYDANNLLLQQAKKEVLDIQFEKIQLKNCLTRLSQAQLMIKKLKKFSPFGLELFVERVNDTLSTESLTERIKQIQ
NSWF

Sequences:

>Translated_804_residues
MTLPKHSLIEQWFNFKKWEPLPFQKEAWLKFLEGKSGLISVPTGAGKTYAAYLSALSKLHEDPKKGIQILYITPLRALAK
DLESALKAPIDDLKLIYRVERRTGDTSYIKKEKQNKHPPEILITTPESLAVMLCNGHATSQFSYLQSIIVDEWHELLASK
RGVLFELCLSRLKAWKPSVQIWGLTATIGNIQQAAQVCVGVDRSPIIVNAKMEREVILTAVLPESLDKLPWTGRLGLRLL
PYVLNRLNFNQSTLIFTNTRSQTERWYQAILEARPEWKNLIAIHHSAIDKKTREGIEEGIKFGSIRFVVCTSSLDLGIDL
PRVEKVIQIGSPKSVARLLQRAGRSSHRPLTPCYIEVVPTHALELIEIQAYRLAIKEHHIESRLPLKNCYDVLMQHMMTC
AIGEGFQKDELFSQIKTTACFQDLSLKDFEDCLHFLISGGNSLKAYPEYKKLVYSNDKYIVEDKGLIRRHKMSIGTISSD
SQITVKWTKGKAIGMIEESFLTNLKPGDHFLFGGKQLQLVQYRDMTAYVRLAKHKQKHAAVWRGSHLPFSASLGVELRKV
CEQKISLNSSDQEKFLLDQIIQLQQKFSYLPTTKQLLIELTKSQEGWHLFVYPFEGKIIHQGLALLVAHRLSKKASQTFT
ISTNDYGFELLSRKSFQEEMLTTELFSTQYMNEDIQELINTQEIGKRYFRDIARIAGLIFPGYPHKHKTNRQVQISSSLL
FDVLQKYDANNLLLQQAKKEVLDIQFEKIQLKNCLTRLSQAQLMIKKLKKFSPFGLELFVERVNDTLSTESLTERIKQIQ
NSWF
>Mature_803_residues
TLPKHSLIEQWFNFKKWEPLPFQKEAWLKFLEGKSGLISVPTGAGKTYAAYLSALSKLHEDPKKGIQILYITPLRALAKD
LESALKAPIDDLKLIYRVERRTGDTSYIKKEKQNKHPPEILITTPESLAVMLCNGHATSQFSYLQSIIVDEWHELLASKR
GVLFELCLSRLKAWKPSVQIWGLTATIGNIQQAAQVCVGVDRSPIIVNAKMEREVILTAVLPESLDKLPWTGRLGLRLLP
YVLNRLNFNQSTLIFTNTRSQTERWYQAILEARPEWKNLIAIHHSAIDKKTREGIEEGIKFGSIRFVVCTSSLDLGIDLP
RVEKVIQIGSPKSVARLLQRAGRSSHRPLTPCYIEVVPTHALELIEIQAYRLAIKEHHIESRLPLKNCYDVLMQHMMTCA
IGEGFQKDELFSQIKTTACFQDLSLKDFEDCLHFLISGGNSLKAYPEYKKLVYSNDKYIVEDKGLIRRHKMSIGTISSDS
QITVKWTKGKAIGMIEESFLTNLKPGDHFLFGGKQLQLVQYRDMTAYVRLAKHKQKHAAVWRGSHLPFSASLGVELRKVC
EQKISLNSSDQEKFLLDQIIQLQQKFSYLPTTKQLLIELTKSQEGWHLFVYPFEGKIIHQGLALLVAHRLSKKASQTFTI
STNDYGFELLSRKSFQEEMLTTELFSTQYMNEDIQELINTQEIGKRYFRDIARIAGLIFPGYPHKHKTNRQVQISSSLLF
DVLQKYDANNLLLQQAKKEVLDIQFEKIQLKNCLTRLSQAQLMIKKLKKFSPFGLELFVERVNDTLSTESLTERIKQIQN
SWF

Specific function: Unknown

COG id: COG1201

COG function: function code R; Lhr-like helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI38569503, Length=338, Percent_Identity=24.2603550295858, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI38569505, Length=338, Percent_Identity=25.1479289940828, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1787942, Length=876, Percent_Identity=26.027397260274, Blast_Score=227, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI17537519, Length=357, Percent_Identity=26.0504201680672, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71987143, Length=374, Percent_Identity=25.668449197861, Blast_Score=81, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI9755332, Length=370, Percent_Identity=26.4864864864865, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6321020, Length=387, Percent_Identity=24.8062015503876, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321856, Length=369, Percent_Identity=24.9322493224932, Blast_Score=71, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR013701
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR017170 [H]

Pfam domain/function: PF00270 DEAD; PF08494 DEAD_assoc; PF00271 Helicase_C [H]

EC number: 3.6.1.-

Molecular weight: Translated: 92223; Mature: 92092

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPKHSLIEQWFNFKKWEPLPFQKEAWLKFLEGKSGLISVPTGAGKTYAAYLSALSKLH
CCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHH
EDPKKGIQILYITPLRALAKDLESALKAPIDDLKLIYRVERRTGDTSYIKKEKQNKHPPE
CCHHHCEEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCE
ILITTPESLAVMLCNGHATSQFSYLQSIIVDEWHELLASKRGVLFELCLSRLKAWKPSVQ
EEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEE
IWGLTATIGNIQQAAQVCVGVDRSPIIVNAKMEREVILTAVLPESLDKLPWTGRLGLRLL
EEEEEHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHH
PYVLNRLNFNQSTLIFTNTRSQTERWYQAILEARPEWKNLIAIHHSAIDKKTREGIEEGI
HHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
KFGSIRFVVCTSSLDLGIDLPRVEKVIQIGSPKSVARLLQRAGRSSHRPLTPCYIEVVPT
CCCCEEEEEEECCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCEEEEEECH
HALELIEIQAYRLAIKEHHIESRLPLKNCYDVLMQHMMTCAIGEGFQKDELFSQIKTTAC
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
FQDLSLKDFEDCLHFLISGGNSLKAYPEYKKLVYSNDKYIVEDKGLIRRHKMSIGTISSD
HHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHEECCCCEEEECCCHHHHHHCCEEEECCC
SQITVKWTKGKAIGMIEESFLTNLKPGDHFLFGGKQLQLVQYRDMTAYVRLAKHKQKHAA
CEEEEEEECCCEEEHHHHHHHHCCCCCCEEEECCCEEEEEEECCHHHHHHHHHHHHHHHH
VWRGSHLPFSASLGVELRKVCEQKISLNSSDQEKFLLDQIIQLQQKFSYLPTTKQLLIEL
HCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
TKSQEGWHLFVYPFEGKIIHQGLALLVAHRLSKKASQTFTISTNDYGFELLSRKSFQEEM
HCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHH
LTTELFSTQYMNEDIQELINTQEIGKRYFRDIARIAGLIFPGYPHKHKTNRQVQISSSLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHH
FDVLQKYDANNLLLQQAKKEVLDIQFEKIQLKNCLTRLSQAQLMIKKLKKFSPFGLELFV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ERVNDTLSTESLTERIKQIQNSWF
HHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLPKHSLIEQWFNFKKWEPLPFQKEAWLKFLEGKSGLISVPTGAGKTYAAYLSALSKLH
CCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHH
EDPKKGIQILYITPLRALAKDLESALKAPIDDLKLIYRVERRTGDTSYIKKEKQNKHPPE
CCHHHCEEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCE
ILITTPESLAVMLCNGHATSQFSYLQSIIVDEWHELLASKRGVLFELCLSRLKAWKPSVQ
EEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEE
IWGLTATIGNIQQAAQVCVGVDRSPIIVNAKMEREVILTAVLPESLDKLPWTGRLGLRLL
EEEEEHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHH
PYVLNRLNFNQSTLIFTNTRSQTERWYQAILEARPEWKNLIAIHHSAIDKKTREGIEEGI
HHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
KFGSIRFVVCTSSLDLGIDLPRVEKVIQIGSPKSVARLLQRAGRSSHRPLTPCYIEVVPT
CCCCEEEEEEECCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCEEEEEECH
HALELIEIQAYRLAIKEHHIESRLPLKNCYDVLMQHMMTCAIGEGFQKDELFSQIKTTAC
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
FQDLSLKDFEDCLHFLISGGNSLKAYPEYKKLVYSNDKYIVEDKGLIRRHKMSIGTISSD
HHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHEECCCCEEEECCCHHHHHHCCEEEECCC
SQITVKWTKGKAIGMIEESFLTNLKPGDHFLFGGKQLQLVQYRDMTAYVRLAKHKQKHAA
CEEEEEEECCCEEEHHHHHHHHCCCCCCEEEECCCEEEEEEECCHHHHHHHHHHHHHHHH
VWRGSHLPFSASLGVELRKVCEQKISLNSSDQEKFLLDQIIQLQQKFSYLPTTKQLLIEL
HCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
TKSQEGWHLFVYPFEGKIIHQGLALLVAHRLSKKASQTFTISTNDYGFELLSRKSFQEEM
HCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHH
LTTELFSTQYMNEDIQELINTQEIGKRYFRDIARIAGLIFPGYPHKHKTNRQVQISSSLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHH
FDVLQKYDANNLLLQQAKKEVLDIQFEKIQLKNCLTRLSQAQLMIKKLKKFSPFGLELFV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ERVNDTLSTESLTERIKQIQNSWF
HHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]