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The map label for this gene is ycbL [H]

Identifier: 46446576

GI number: 46446576

Start: 1139401

End: 1140807

Strand: Reverse

Name: ycbL [H]

Synonym: pc0942

Alternate gene names: 46446576

Gene position: 1140807-1139401 (Counterclockwise)

Preceding gene: 46446578

Following gene: 46446574

Centisome position: 47.25

GC content: 36.74

Gene sequence:

>1407_bases
ATGTTTTTTCAAAAAATTTACACTCCAGGCCTGGCAATTAATACTTATTTGTTAGGAGATGAAACGACCAAAGAATGCGT
CGTGATAGATCCTACTCGTGTAGTTACTCCGATCATTATGGCTGCTGAAAACGCTGAAATGCACATCAAAGCTATATTGG
AAACGCATGTGCATGCTGACTTCATTTCCGGGGCTAGAGAATTAAAATTTCAATTAAAAAATGCTCCAATTATTTATTCT
TCGGGGTTTGGCGGAGAGCAATGGGTTCCCGCTTATGCTGATCATATTGTCAAAGAAGAAGATGTTTTGTCATTCGGATC
TATTCGTTTAAAACCTCTGCATACGCCAGGACATACGCCTGAACATATCATGTGGATTTGTTATGATGAAACAAGAAGCC
ATGATCTTCCCTGGTTCATTTTTTCCGGGGATTGTTTATTTGTAGGTAGTGTAGGAAGACCGGATTTATTAGGAGAAAAT
GCGTTTAACTTTCTTGCTAAAGAGCTTTATCAAAGCTTATTCGTCAGGATTGCTCATTTACCGGATTCTGTTGAAGTCTT
TCCTGCACATGGAGCCGGCTCTCTTTGTGGTAAAAACATTGGAGGAGTAGACGCAACAACTTTAGGTTACGAGAGAACTT
GTAATCCTTATTTAAATCCAATTGAAGAAACAGAATGGATTAAAAGTATTAGTCAGGATTTGCCTGCAATTCCTCCCTAT
TTTTCTCTCATGAAAAAAATAAATGTCTCTAATCCACCTTTATTGAGTGAACTAAAAGTTGAAAAAGTCTGTTCTGAAAG
AGATTTAGATTTGAATTTGTGTTTTTTATTAGATGTTCGTTATCCAGAACTTTTTGCGCGATTTCATCTTCCAGGGTCCG
TCAATATCCCTATGACACCTTCTTTTTATTCATGGGCAGGATGGCTTATTCCCCATAATATCCCATTAATCATTATTACA
AACCGTGAAAATCAAATGAATGATATCGTGTCTCAATTGCGCTTAATTGGCTTTGATCAGCCCTTTTATTTATTTGTACT
AAAAGATGACGCAGAAAAAAAGATGAATCGTATTGAGTGTTTTAGTTATCTAACCCCAGAAGAACTTGCAAAAAGATTGC
ACGACCCGAAAGAAAATGTTTTTGTTTTAGATGTACGAACCACCTCAGAATGGCACTCTGGCCATATTGCAGATGCTTAT
CACGTGGAGTTAAATAATCTTTATCAATATATGCATAAAATCCCTCAAAATCGTTTAATTGCAGTCATTTGCCGATCTGG
AATACGCGCGTCTACAGCAATATCCCTACTAAAAAAATATGGCTTTAATCACGTTGTCAATGTAAGAGGAGGAATGCAAG
CTTGGATCGACCTTGAATTTCCTATAATTACTTCTGATAAAGAATAA

Upstream 100 bases:

>100_bases
TTCGAAATTATGCTCAGATAAAATCTATTTATGGTAAACGGTTAATGTACTAAATACTGTGAAAAACCATTAATTTTTCC
AAAAATGTTATAGTTAATAT

Downstream 100 bases:

>100_bases
AAAATAAGGCTGCTTATTTAATATCTTTCCTAGTGGTTTTTCAACCACACAAATCTCTGTTTAAGGTGAGCTAACCACTT
ATTTTTTAATGATTTTCTAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MFFQKIYTPGLAINTYLLGDETTKECVVIDPTRVVTPIIMAAENAEMHIKAILETHVHADFISGARELKFQLKNAPIIYS
SGFGGEQWVPAYADHIVKEEDVLSFGSIRLKPLHTPGHTPEHIMWICYDETRSHDLPWFIFSGDCLFVGSVGRPDLLGEN
AFNFLAKELYQSLFVRIAHLPDSVEVFPAHGAGSLCGKNIGGVDATTLGYERTCNPYLNPIEETEWIKSISQDLPAIPPY
FSLMKKINVSNPPLLSELKVEKVCSERDLDLNLCFLLDVRYPELFARFHLPGSVNIPMTPSFYSWAGWLIPHNIPLIIIT
NRENQMNDIVSQLRLIGFDQPFYLFVLKDDAEKKMNRIECFSYLTPEELAKRLHDPKENVFVLDVRTTSEWHSGHIADAY
HVELNNLYQYMHKIPQNRLIAVICRSGIRASTAISLLKKYGFNHVVNVRGGMQAWIDLEFPIITSDKE

Sequences:

>Translated_468_residues
MFFQKIYTPGLAINTYLLGDETTKECVVIDPTRVVTPIIMAAENAEMHIKAILETHVHADFISGARELKFQLKNAPIIYS
SGFGGEQWVPAYADHIVKEEDVLSFGSIRLKPLHTPGHTPEHIMWICYDETRSHDLPWFIFSGDCLFVGSVGRPDLLGEN
AFNFLAKELYQSLFVRIAHLPDSVEVFPAHGAGSLCGKNIGGVDATTLGYERTCNPYLNPIEETEWIKSISQDLPAIPPY
FSLMKKINVSNPPLLSELKVEKVCSERDLDLNLCFLLDVRYPELFARFHLPGSVNIPMTPSFYSWAGWLIPHNIPLIIIT
NRENQMNDIVSQLRLIGFDQPFYLFVLKDDAEKKMNRIECFSYLTPEELAKRLHDPKENVFVLDVRTTSEWHSGHIADAY
HVELNNLYQYMHKIPQNRLIAVICRSGIRASTAISLLKKYGFNHVVNVRGGMQAWIDLEFPIITSDKE
>Mature_468_residues
MFFQKIYTPGLAINTYLLGDETTKECVVIDPTRVVTPIIMAAENAEMHIKAILETHVHADFISGARELKFQLKNAPIIYS
SGFGGEQWVPAYADHIVKEEDVLSFGSIRLKPLHTPGHTPEHIMWICYDETRSHDLPWFIFSGDCLFVGSVGRPDLLGEN
AFNFLAKELYQSLFVRIAHLPDSVEVFPAHGAGSLCGKNIGGVDATTLGYERTCNPYLNPIEETEWIKSISQDLPAIPPY
FSLMKKINVSNPPLLSELKVEKVCSERDLDLNLCFLLDVRYPELFARFHLPGSVNIPMTPSFYSWAGWLIPHNIPLIIIT
NRENQMNDIVSQLRLIGFDQPFYLFVLKDDAEKKMNRIECFSYLTPEELAKRLHDPKENVFVLDVRTTSEWHSGHIADAY
HVELNNLYQYMHKIPQNRLIAVICRSGIRASTAISLLKKYGFNHVVNVRGGMQAWIDLEFPIITSDKE

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=229, Percent_Identity=28.3842794759825, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI116642887, Length=231, Percent_Identity=28.1385281385281, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI21703352, Length=231, Percent_Identity=28.1385281385281, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1787158, Length=235, Percent_Identity=28.936170212766, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17538952, Length=224, Percent_Identity=29.0178571428571, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17536925, Length=149, Percent_Identity=30.2013422818792, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356335, Length=187, Percent_Identity=31.0160427807487, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24667703, Length=187, Percent_Identity=31.0160427807487, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24667711, Length=187, Percent_Identity=31.0160427807487, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI221330176, Length=195, Percent_Identity=26.6666666666667, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 53224; Mature: 53224

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFQKIYTPGLAINTYLLGDETTKECVVIDPTRVVTPIIMAAENAEMHIKAILETHVHAD
CCCHHHCCCCEEEEEEEECCCCCCCEEEECCHHHHHHHEEEECCCCHHHHHHHHHHHHHH
FISGARELKFQLKNAPIIYSSGFGGEQWVPAYADHIVKEEDVLSFGSIRLKPLHTPGHTP
HHCCHHHEEEEECCCCEEEECCCCCCCCCHHHHHHHCCHHHHEEECCEEEEEECCCCCCC
EHIMWICYDETRSHDLPWFIFSGDCLFVGSVGRPDLLGENAFNFLAKELYQSLFVRIAHL
CEEEEEEEECCCCCCCCEEEEECCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
PDSVEVFPAHGAGSLCGKNIGGVDATTLGYERTCNPYLNPIEETEWIKSISQDLPAIPPY
CCCCEEEECCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHH
FSLMKKINVSNPPLLSELKVEKVCSERDLDLNLCFLLDVRYPELFARFHLPGSVNIPMTP
HHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHEEECCCCCCCCCCC
SFYSWAGWLIPHNIPLIIITNRENQMNDIVSQLRLIGFDQPFYLFVLKDDAEKKMNRIEC
CHHHHEEEEECCCCCEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHH
FSYLTPEELAKRLHDPKENVFVLDVRTTSEWHSGHIADAYHVELNNLYQYMHKIPQNRLI
HHCCCHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCEEEEEEHHHHHHHHHHCCCCCEE
AVICRSGIRASTAISLLKKYGFNHVVNVRGGMQAWIDLEFPIITSDKE
EEEECCCCCHHHHHHHHHHCCCCEEEECCCCCEEEEEEEEEEEECCCC
>Mature Secondary Structure
MFFQKIYTPGLAINTYLLGDETTKECVVIDPTRVVTPIIMAAENAEMHIKAILETHVHAD
CCCHHHCCCCEEEEEEEECCCCCCCEEEECCHHHHHHHEEEECCCCHHHHHHHHHHHHHH
FISGARELKFQLKNAPIIYSSGFGGEQWVPAYADHIVKEEDVLSFGSIRLKPLHTPGHTP
HHCCHHHEEEEECCCCEEEECCCCCCCCCHHHHHHHCCHHHHEEECCEEEEEECCCCCCC
EHIMWICYDETRSHDLPWFIFSGDCLFVGSVGRPDLLGENAFNFLAKELYQSLFVRIAHL
CEEEEEEEECCCCCCCCEEEEECCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
PDSVEVFPAHGAGSLCGKNIGGVDATTLGYERTCNPYLNPIEETEWIKSISQDLPAIPPY
CCCCEEEECCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHH
FSLMKKINVSNPPLLSELKVEKVCSERDLDLNLCFLLDVRYPELFARFHLPGSVNIPMTP
HHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHEEECCCCCCCCCCC
SFYSWAGWLIPHNIPLIIITNRENQMNDIVSQLRLIGFDQPFYLFVLKDDAEKKMNRIEC
CHHHHEEEEECCCCCEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHH
FSYLTPEELAKRLHDPKENVFVLDVRTTSEWHSGHIADAYHVELNNLYQYMHKIPQNRLI
HHCCCHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCEEEEEEHHHHHHHHHHCCCCCEE
AVICRSGIRASTAISLLKKYGFNHVVNVRGGMQAWIDLEFPIITSDKE
EEEECCCCCHHHHHHHHHHCCCCEEEECCCCCEEEEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]