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The map label for this gene is sctV [H]

Identifier: 46446383

GI number: 46446383

Start: 924380

End: 926560

Strand: Reverse

Name: sctV [H]

Synonym: pc0749

Alternate gene names: 46446383

Gene position: 926560-924380 (Counterclockwise)

Preceding gene: 46446384

Following gene: 46446382

Centisome position: 38.38

GC content: 39.75

Gene sequence:

>2181_bases
ATGAATGCCATTCGTAAAATCCTAGATGGAATTACAGCTCGATTAGGCGGAGATCGCTCGCTCGAAGCAATTTCGAAATC
CAGCGACATTGCATTAGCCGTTTTAATCATCGGTATTCTTGTTATGATTATTTTTCCTGTCAATCCCCATGTGATTGACT
ATTTAATCGCTATCAATCTTTCTTCTTCAATTGCCCTTTTAATGGTTGCTCTTTACATTCCAAGCGCTGTTCATTTGTCT
ATTTTTCCTTCTCTGCTTTTGATTACCACGTTATACCGCTTAGGATTAAATATTGCTTCTACTAGACAAATTCTTTTACA
CGCTAATGCTGGAGAAATCATTTTCCAGTTCGGTAACTTCGTCGTTGGAGGAAATTTCGTCGTTGGAGGCGTTATCTTCT
TAATTATCACTTTAGTTCAGTTCTTAGTGATCACAAAAGGGGCAGAAAGAGTCGCCGAAGTCGCTGCCCGTTTTACATTG
GATGCGATGCCTGGTAAACAAATGAGCATCGACGCAGACATGCGTGCAGGAATTTTGGATTCCAATCAAGCTCGCGAAAA
AAGATTAGCCATCCAAAGAGAGAGTCAATTATATGGAGCAATGGACGGGGCAATGAAGTTCGTTAAAGGAGATGCGATTG
CAGGTATCGTCATTACTTTAATTAATGTTATTGGTGGAATGATCATCGGAATGACCATGAATGAAATGGAAGCAAGTGAT
GCAGCCAAAACTTATGCGTTATTATCTATTGGAGATGGATTGATCTCTCAAATTCCCGCTCTTTTAATTTCGATTACTGC
CGGTATTGTGACAACTCGTGTTTCTGGAAGCGAAAAAGTTGAAAATTTAGGGACTGAAATCTCTGGTCAAATTTTAAAAC
AACCTAAAGCTCTTATGATTACCGCCGCATTTTTGATGGGCATGAGCTTGGTTCCCGGTTTTCCGATGCCTCCTTTTCTA
ATTGCTGCTGCTGCACTTGGTTTGATTGGTTATGCTTTATGGAGCAATGAACAAAAAGCCTTGTTAGGTGGAGGAAGCGT
TGGTTCCATGGGTGGAGGGACAATTCAGTCTGCCGCTGGTAGCGATTCTTCAGTAGAAACCTCTGTAAGAGGTCATAAAG
TTATCTCTGGGGGTGGAGTTGACAGCTATGCATTAACACTCCCAGTCGTATTAGAGGTTGGCAGAGGGTTGTCTATAGAA
ATTCAAAAAGCAAATAAAGGGACAAGCTTTATCGATCAAATGATTCCCAAAATGAGACAAGCACTTTACGCCGATTTAGG
AGTTCGTTTTCCCGGTGTACATGTGCGAACTGACTCACCCATTTTAGATAAAGATGAATACTCAATTCACTTAAATGAAG
TTCCCATTGTGCGAGGAAAAGTTTTAGAAAATCATCTACTTACCAATGAATCGGAAGAAAACCTTAAACGTTATAATCTT
CCTTTCGTTTCTTATAAAAACTCGTTAGGTCTTCCTTCTCTTTGGGTGGATGCAAAAAACAAAGAGCTATTAGATAAAGC
TGGAATCCGTTACTGGAGCTCTTTGGAAGTGATGATCTTACATTTATCTTACTTCTTCCGTCATTATGCGAATGAATTTG
TTGGAATTCAAGAAGTTAAATCGATGTTAGAGTTTGTTGAAAAATCTTTTCCCGATCTCGTCAAAGAAGTCACACGTTTG
ATACCGCTTCAAAAAATGACAGATATTTTCAAACGTTTGATCCAAGAGCAAATTTCGATCAAAGATTTAAGAACAATTTT
AGAAGCCCTTGGTGAGTGGGCCCAAACTGAAAAAGATACCGTTCTTTTGACAGAATACGTCCGCTCATCGCTCAAAAGGT
TTATTAGCTATAAATATTCTCAGGGTCAGTCCGTTCTATCAGTCTATATTTTAGACCCTGAAATTGAAGATATGGTAAGA
GGTGCCATTAAACAGACATCAGCCGGGTCTTATTTAGCCCTAGATCCTGATTCTGTTCAACTTATTTTACAAGGTGTACG
CAATACGGTATCTCCTCCTCCTCCCGGTGGACAACCGCCCGTTATTTTGACTGCAATCGACGTGAGACGATTCGTTCGAA
AACTCATTGAAATGGAATTTACTGATATTTCTGTGGTTTCTTACCAAGAGATTGTTCCTGAAATCCGCATACAGCCTTTA
GGGCGTATCCAGATTTCTTAA

Upstream 100 bases:

>100_bases
GCAGAAATTATGCGTTGGATTGCCTCTTTAAAAGATGGAACTGAAATCCCCGAGCCTCTAAACTTATAAGCTTTGAAAAA
TTATCGGAGAAAAACCTGAC

Downstream 100 bases:

>100_bases
ATTCTTAAAACTCTCTGATGGGAGGTGGGATCATGAGTATTCCTTCATCTTTTAATGCAGCTGCTGCAAATGCTGCCTTT
GCTGCAAAAGATGCCGCTTT

Product: type III secretion pathway protein SctV

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 726; Mature: 726

Protein sequence:

>726_residues
MNAIRKILDGITARLGGDRSLEAISKSSDIALAVLIIGILVMIIFPVNPHVIDYLIAINLSSSIALLMVALYIPSAVHLS
IFPSLLLITTLYRLGLNIASTRQILLHANAGEIIFQFGNFVVGGNFVVGGVIFLIITLVQFLVITKGAERVAEVAARFTL
DAMPGKQMSIDADMRAGILDSNQAREKRLAIQRESQLYGAMDGAMKFVKGDAIAGIVITLINVIGGMIIGMTMNEMEASD
AAKTYALLSIGDGLISQIPALLISITAGIVTTRVSGSEKVENLGTEISGQILKQPKALMITAAFLMGMSLVPGFPMPPFL
IAAAALGLIGYALWSNEQKALLGGGSVGSMGGGTIQSAAGSDSSVETSVRGHKVISGGGVDSYALTLPVVLEVGRGLSIE
IQKANKGTSFIDQMIPKMRQALYADLGVRFPGVHVRTDSPILDKDEYSIHLNEVPIVRGKVLENHLLTNESEENLKRYNL
PFVSYKNSLGLPSLWVDAKNKELLDKAGIRYWSSLEVMILHLSYFFRHYANEFVGIQEVKSMLEFVEKSFPDLVKEVTRL
IPLQKMTDIFKRLIQEQISIKDLRTILEALGEWAQTEKDTVLLTEYVRSSLKRFISYKYSQGQSVLSVYILDPEIEDMVR
GAIKQTSAGSYLALDPDSVQLILQGVRNTVSPPPPGGQPPVILTAIDVRRFVRKLIEMEFTDISVVSYQEIVPEIRIQPL
GRIQIS

Sequences:

>Translated_726_residues
MNAIRKILDGITARLGGDRSLEAISKSSDIALAVLIIGILVMIIFPVNPHVIDYLIAINLSSSIALLMVALYIPSAVHLS
IFPSLLLITTLYRLGLNIASTRQILLHANAGEIIFQFGNFVVGGNFVVGGVIFLIITLVQFLVITKGAERVAEVAARFTL
DAMPGKQMSIDADMRAGILDSNQAREKRLAIQRESQLYGAMDGAMKFVKGDAIAGIVITLINVIGGMIIGMTMNEMEASD
AAKTYALLSIGDGLISQIPALLISITAGIVTTRVSGSEKVENLGTEISGQILKQPKALMITAAFLMGMSLVPGFPMPPFL
IAAAALGLIGYALWSNEQKALLGGGSVGSMGGGTIQSAAGSDSSVETSVRGHKVISGGGVDSYALTLPVVLEVGRGLSIE
IQKANKGTSFIDQMIPKMRQALYADLGVRFPGVHVRTDSPILDKDEYSIHLNEVPIVRGKVLENHLLTNESEENLKRYNL
PFVSYKNSLGLPSLWVDAKNKELLDKAGIRYWSSLEVMILHLSYFFRHYANEFVGIQEVKSMLEFVEKSFPDLVKEVTRL
IPLQKMTDIFKRLIQEQISIKDLRTILEALGEWAQTEKDTVLLTEYVRSSLKRFISYKYSQGQSVLSVYILDPEIEDMVR
GAIKQTSAGSYLALDPDSVQLILQGVRNTVSPPPPGGQPPVILTAIDVRRFVRKLIEMEFTDISVVSYQEIVPEIRIQPL
GRIQIS
>Mature_726_residues
MNAIRKILDGITARLGGDRSLEAISKSSDIALAVLIIGILVMIIFPVNPHVIDYLIAINLSSSIALLMVALYIPSAVHLS
IFPSLLLITTLYRLGLNIASTRQILLHANAGEIIFQFGNFVVGGNFVVGGVIFLIITLVQFLVITKGAERVAEVAARFTL
DAMPGKQMSIDADMRAGILDSNQAREKRLAIQRESQLYGAMDGAMKFVKGDAIAGIVITLINVIGGMIIGMTMNEMEASD
AAKTYALLSIGDGLISQIPALLISITAGIVTTRVSGSEKVENLGTEISGQILKQPKALMITAAFLMGMSLVPGFPMPPFL
IAAAALGLIGYALWSNEQKALLGGGSVGSMGGGTIQSAAGSDSSVETSVRGHKVISGGGVDSYALTLPVVLEVGRGLSIE
IQKANKGTSFIDQMIPKMRQALYADLGVRFPGVHVRTDSPILDKDEYSIHLNEVPIVRGKVLENHLLTNESEENLKRYNL
PFVSYKNSLGLPSLWVDAKNKELLDKAGIRYWSSLEVMILHLSYFFRHYANEFVGIQEVKSMLEFVEKSFPDLVKEVTRL
IPLQKMTDIFKRLIQEQISIKDLRTILEALGEWAQTEKDTVLLTEYVRSSLKRFISYKYSQGQSVLSVYILDPEIEDMVR
GAIKQTSAGSYLALDPDSVQLILQGVRNTVSPPPPGGQPPVILTAIDVRRFVRKLIEMEFTDISVVSYQEIVPEIRIQPL
GRIQIS

Specific function: Could be involved in the secretion of the yop virulence proteins [H]

COG id: COG4789

COG function: function code U; Type III secretory pathway, component EscV

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=691, Percent_Identity=34.2981186685962, Blast_Score=350, Evalue=2e-97,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001712
- InterPro:   IPR006302 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 79144; Mature: 79144

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: PS00318 HMG_COA_REDUCTASE_2 ; PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAIRKILDGITARLGGDRSLEAISKSSDIALAVLIIGILVMIIFPVNPHVIDYLIAINL
CCHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHEECC
SSSIALLMVALYIPSAVHLSIFPSLLLITTLYRLGLNIASTRQILLHANAGEIIFQFGNF
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHEECCCE
VVGGNFVVGGVIFLIITLVQFLVITKGAERVAEVAARFTLDAMPGKQMSIDADMRAGILD
EECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEECCHHHCCCCC
SNQAREKRLAIQRESQLYGAMDGAMKFVKGDAIAGIVITLINVIGGMIIGMTMNEMEASD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AAKTYALLSIGDGLISQIPALLISITAGIVTTRVSGSEKVENLGTEISGQILKQPKALMI
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHCCHHHHHHHHCCHHHHH
TAAFLMGMSLVPGFPMPPFLIAAAALGLIGYALWSNEQKALLGGGSVGSMGGGTIQSAAG
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCC
SDSSVETSVRGHKVISGGGVDSYALTLPVVLEVGRGLSIEIQKANKGTSFIDQMIPKMRQ
CCCCCCHHCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHH
ALYADLGVRFPGVHVRTDSPILDKDEYSIHLNEVPIVRGKVLENHLLTNESEENLKRYNL
HHHHHCCCCCCCEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHCC
PFVSYKNSLGLPSLWVDAKNKELLDKAGIRYWSSLEVMILHLSYFFRHYANEFVGIQEVK
CEEEECCCCCCCEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
SMLEFVEKSFPDLVKEVTRLIPLQKMTDIFKRLIQEQISIKDLRTILEALGEWAQTEKDT
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
VLLTEYVRSSLKRFISYKYSQGQSVLSVYILDPEIEDMVRGAIKQTSAGSYLALDPDSVQ
HHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHCCCCCEEEECCHHHH
LILQGVRNTVSPPPPGGQPPVILTAIDVRRFVRKLIEMEFTDISVVSYQEIVPEIRIQPL
HHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCC
GRIQIS
CCEEEC
>Mature Secondary Structure
MNAIRKILDGITARLGGDRSLEAISKSSDIALAVLIIGILVMIIFPVNPHVIDYLIAINL
CCHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHEECC
SSSIALLMVALYIPSAVHLSIFPSLLLITTLYRLGLNIASTRQILLHANAGEIIFQFGNF
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHEECCCE
VVGGNFVVGGVIFLIITLVQFLVITKGAERVAEVAARFTLDAMPGKQMSIDADMRAGILD
EECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEECCHHHCCCCC
SNQAREKRLAIQRESQLYGAMDGAMKFVKGDAIAGIVITLINVIGGMIIGMTMNEMEASD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AAKTYALLSIGDGLISQIPALLISITAGIVTTRVSGSEKVENLGTEISGQILKQPKALMI
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHCCHHHHHHHHCCHHHHH
TAAFLMGMSLVPGFPMPPFLIAAAALGLIGYALWSNEQKALLGGGSVGSMGGGTIQSAAG
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCC
SDSSVETSVRGHKVISGGGVDSYALTLPVVLEVGRGLSIEIQKANKGTSFIDQMIPKMRQ
CCCCCCHHCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHH
ALYADLGVRFPGVHVRTDSPILDKDEYSIHLNEVPIVRGKVLENHLLTNESEENLKRYNL
HHHHHCCCCCCCEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHCC
PFVSYKNSLGLPSLWVDAKNKELLDKAGIRYWSSLEVMILHLSYFFRHYANEFVGIQEVK
CEEEECCCCCCCEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
SMLEFVEKSFPDLVKEVTRLIPLQKMTDIFKRLIQEQISIKDLRTILEALGEWAQTEKDT
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
VLLTEYVRSSLKRFISYKYSQGQSVLSVYILDPEIEDMVRGAIKQTSAGSYLALDPDSVQ
HHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHCCCCCEEEECCHHHH
LILQGVRNTVSPPPPGGQPPVILTAIDVRRFVRKLIEMEFTDISVVSYQEIVPEIRIQPL
HHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCCCC
GRIQIS
CCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11402007 [H]