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The map label for this gene is dapB [H]

Identifier: 46446321

GI number: 46446321

Start: 835716

End: 836372

Strand: Reverse

Name: dapB [H]

Synonym: pc0687

Alternate gene names: 46446321

Gene position: 836372-835716 (Counterclockwise)

Preceding gene: 46446322

Following gene: 46446320

Centisome position: 34.64

GC content: 35.31

Gene sequence:

>657_bases
TTGGGATATGGAAAGATCGGGAAATTAATTGAAAAAATAGCTTTGGAAAAAGGACATGAAATCATTGCTATTATCACACG
TGAGGATAACGATTTTCAAAAAAAATTAGAGCAGGTAGACGTATTAATTGACTTTAGTCATCCCGAGGTTGTTTTGGATC
ATATCAATTGGAGTATTATCTTAAATAAACCTATTGTCATTGGAACGACAGGATGGGAAGATCAATTAGAGCAAGCGCGT
GAACAAATTCAAAAAAGTACGACCAGTTGCTTGTATTCGCCTAATTTCTTAATTGGTGTTCAATTATTTAAACAAATAGT
CTCTTATGCAGCTCAATTAATCCGTCCTTTTGAAGAATTTGATATTGCTGGAGTCGAGCTTCATCATAACAAAAAATTAG
ATACACCGTCAGGAACCGCAAAAGCCTTAATTAAAAACATCCAAGAAGTTTTACCCCACTATTCATTGAAATTTAGTAGC
ATTCGATGCGGACATATGCCTGGTACGCATACCCTTTATTTTGATAGCCCAACGGATACAATTATCCTCACTCATGAAGC
AAGAAATCGCGAAGGTTTTGCTATGGGAGCCATCAAAGCAGCTGAATGGTTGAAAGATAAACAAGGTTTTTTTACCATTG
AAGATTTAGTATTTTAG

Upstream 100 bases:

>100_bases
AGCAAAAAATGAAAATGAATCAATTGTGGAGTGCTATTAATAAAAAATCAGAAAAAGTCTCAATAAATAAAAAAAAGGGC
CAAAAATGAAAATTGGTTTA

Downstream 100 bases:

>100_bases
ACAGTTTAACCGAAGCAAAATATGTATTTAAAAGGTCTTTATACAGCCTTAATTACCCCTTTTACCCCAACTGGTCAATT
AGATGAAGAAGGGTTAAAAA

Product: putative dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR [H]

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MGYGKIGKLIEKIALEKGHEIIAIITREDNDFQKKLEQVDVLIDFSHPEVVLDHINWSIILNKPIVIGTTGWEDQLEQAR
EQIQKSTTSCLYSPNFLIGVQLFKQIVSYAAQLIRPFEEFDIAGVELHHNKKLDTPSGTAKALIKNIQEVLPHYSLKFSS
IRCGHMPGTHTLYFDSPTDTIILTHEARNREGFAMGAIKAAEWLKDKQGFFTIEDLVF

Sequences:

>Translated_218_residues
MGYGKIGKLIEKIALEKGHEIIAIITREDNDFQKKLEQVDVLIDFSHPEVVLDHINWSIILNKPIVIGTTGWEDQLEQAR
EQIQKSTTSCLYSPNFLIGVQLFKQIVSYAAQLIRPFEEFDIAGVELHHNKKLDTPSGTAKALIKNIQEVLPHYSLKFSS
IRCGHMPGTHTLYFDSPTDTIILTHEARNREGFAMGAIKAAEWLKDKQGFFTIEDLVF
>Mature_217_residues
GYGKIGKLIEKIALEKGHEIIAIITREDNDFQKKLEQVDVLIDFSHPEVVLDHINWSIILNKPIVIGTTGWEDQLEQARE
QIQKSTTSCLYSPNFLIGVQLFKQIVSYAAQLIRPFEEFDIAGVELHHNKKLDTPSGTAKALIKNIQEVLPHYSLKFSSI
RCGHMPGTHTLYFDSPTDTIILTHEARNREGFAMGAIKAAEWLKDKQGFFTIEDLVF

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786214, Length=209, Percent_Identity=31.1004784688995, Blast_Score=102, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR011770
- InterPro:   IPR016040 [H]

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N [H]

EC number: =1.3.1.26 [H]

Molecular weight: Translated: 24749; Mature: 24618

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYGKIGKLIEKIALEKGHEIIAIITREDNDFQKKLEQVDVLIDFSHPEVVLDHINWSII
CCCCHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHEEEEECCCCCEEEECCCEEEE
LNKPIVIGTTGWEDQLEQAREQIQKSTTSCLYSPNFLIGVQLFKQIVSYAAQLIRPFEEF
EECCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHC
DIAGVELHHNKKLDTPSGTAKALIKNIQEVLPHYSLKFSSIRCGHMPGTHTLYFDSPTDT
CCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCEEECCCCCCEEEEEECCCCE
IILTHEARNREGFAMGAIKAAEWLKDKQGFFTIEDLVF
EEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEHHHHCC
>Mature Secondary Structure 
GYGKIGKLIEKIALEKGHEIIAIITREDNDFQKKLEQVDVLIDFSHPEVVLDHINWSII
CCCHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHEEEEECCCCCEEEECCCEEEE
LNKPIVIGTTGWEDQLEQAREQIQKSTTSCLYSPNFLIGVQLFKQIVSYAAQLIRPFEEF
EECCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHC
DIAGVELHHNKKLDTPSGTAKALIKNIQEVLPHYSLKFSSIRCGHMPGTHTLYFDSPTDT
CCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCEEECCCCCCEEEEEECCCCE
IILTHEARNREGFAMGAIKAAEWLKDKQGFFTIEDLVF
EEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]