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The map label for this gene is xseA [H]

Identifier: 46446255

GI number: 46446255

Start: 761853

End: 763301

Strand: Reverse

Name: xseA [H]

Synonym: pc0621

Alternate gene names: 46446255

Gene position: 763301-761853 (Counterclockwise)

Preceding gene: 46446257

Following gene: 46446254

Centisome position: 31.61

GC content: 32.99

Gene sequence:

>1449_bases
TTGACTCAAGCCATCAAACTCAATTTAGAGTCGATGTTTCCTTTTATTTATTTACAGGGTGAAATCAGCAATTTTAAAGA
GCAATCATCTGGTCACTTTTACTTTTCTCTAAAAGATGCAACAGCTCAAATTTCTGCTGTGATGTTTAAAGCCGAAGCTT
CTTTGTTGAAAACTCCTCCAAAAGGGGGTGATCATGTCATGATAAAAGGAGAAATAAGTGTTTATCCACCTAAAGGAAAT
TATCAGCTGATTATTCGAGAACTTTCTTATGTGGGTATAGGGGAACTTCTTCAGAAATTAGAACAGCTCAAAATTAAACT
TCATCAAAAAGGTTGGTTTAAAGCGATTCATAAAAAACCGATTCCTCGTTTTCCTAAAAAAATCGGTGTGATAACCAGTC
CTACAGGTGCAGTTATTCAAGATATTTTACAAATTTTAACACGTCGTTTTTCAGGTTTTCATCTCATACTTAATCCTGTC
AAAGTTCAAGGAGAAGGAGCAGCAAAAGAGATTGCTCGTGCAATCGAACAATTCAACCGATATCAATTAGTTGATGTTTT
AATTGTAGGAAGAGGTGGAGGAAGTTTAGAAGATTTATGGCCTTTCAATGAAGAAATTGTTGCTGAAGCTATTTATAACA
GTCAAATCCCGATTATTAGTGCTGTTGGGCATGAAACAGATCATTGCATCGCTGATTATGTTGCAGATATTAGAGCTCCC
ACGCCTTCTGCTGCCGCAGAGATTGTCATTTCAGAAAAAAATCAACAACTTGAACATTTAAAAACTTTAAGAAGGCGAAT
ACAGCAAGCTATTCAAAATCTTATCCAATCAGGGCACTACCGTTTAAAAGGTTTTAGCAAACATCTTTTTATTACTCATC
CTCATGTTATTACAGAATGGAGAATGCAAAAACTTGATGATTTGAAAGAGGATCTTTCTAACCAACTCAAACAGATTATT
ACTTTCAAAAAACATCAATTAGAATCTTTTGCTCGCCAAACCCAGCTCTTGAAACCATCTAATCAAATCATTCACCTTAG
AAAGCATTTGAGAGACTGGAATGGTATTTTTTCAAGAAAAATGCAAGATTTACTTTTGCAAAATAAAAAAAAGATTGAAC
AAATTGAATATCGTTTAAAGCAACAGTGGACCTATTTAATTGGGCAAAAAAAATATCTTTTTAAAGGAAAAGACTATAGA
ATCAAAAATAATCAATTAATCAGAGATCGAATCTTATCTTCAAAACAGAAAATTTTACATATAACTAATATTTTAAAAGC
TGTTGATCCCAAAAATCTTTTAAAACAAGGCTATAGTATTCTATTTGCGGAAAAAGAAGTATTCGTTATAAATTCAATAT
GTAAACTTAAAAAAGGGCAAAAAGCCAAGCTCTTATTATCTGACGGCGAAGCCTTAATCACTATCAACGAAGTGAATCCT
CGTGAATAA

Upstream 100 bases:

>100_bases
CAGATGATATACATCATACGATTCACAAATTGCAATTTTAAAAATTTTTAATTTGAGTTTTATGCAATCAGACACCCCCC
CTCTATTAACGGTTACACAA

Downstream 100 bases:

>100_bases
TCCATCTGATCAAGAACCTACTGCTAGCTTTGAAACAGCTTTATGCCGCTTAGAAGAAATACTTGAAAAGATGAATAGCG
GTACAGTAAGCCTTGATGAA

Product: putative exodeoxyribonuclease VII, large chain

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 482; Mature: 481

Protein sequence:

>482_residues
MTQAIKLNLESMFPFIYLQGEISNFKEQSSGHFYFSLKDATAQISAVMFKAEASLLKTPPKGGDHVMIKGEISVYPPKGN
YQLIIRELSYVGIGELLQKLEQLKIKLHQKGWFKAIHKKPIPRFPKKIGVITSPTGAVIQDILQILTRRFSGFHLILNPV
KVQGEGAAKEIARAIEQFNRYQLVDVLIVGRGGGSLEDLWPFNEEIVAEAIYNSQIPIISAVGHETDHCIADYVADIRAP
TPSAAAEIVISEKNQQLEHLKTLRRRIQQAIQNLIQSGHYRLKGFSKHLFITHPHVITEWRMQKLDDLKEDLSNQLKQII
TFKKHQLESFARQTQLLKPSNQIIHLRKHLRDWNGIFSRKMQDLLLQNKKKIEQIEYRLKQQWTYLIGQKKYLFKGKDYR
IKNNQLIRDRILSSKQKILHITNILKAVDPKNLLKQGYSILFAEKEVFVINSICKLKKGQKAKLLLSDGEALITINEVNP
RE

Sequences:

>Translated_482_residues
MTQAIKLNLESMFPFIYLQGEISNFKEQSSGHFYFSLKDATAQISAVMFKAEASLLKTPPKGGDHVMIKGEISVYPPKGN
YQLIIRELSYVGIGELLQKLEQLKIKLHQKGWFKAIHKKPIPRFPKKIGVITSPTGAVIQDILQILTRRFSGFHLILNPV
KVQGEGAAKEIARAIEQFNRYQLVDVLIVGRGGGSLEDLWPFNEEIVAEAIYNSQIPIISAVGHETDHCIADYVADIRAP
TPSAAAEIVISEKNQQLEHLKTLRRRIQQAIQNLIQSGHYRLKGFSKHLFITHPHVITEWRMQKLDDLKEDLSNQLKQII
TFKKHQLESFARQTQLLKPSNQIIHLRKHLRDWNGIFSRKMQDLLLQNKKKIEQIEYRLKQQWTYLIGQKKYLFKGKDYR
IKNNQLIRDRILSSKQKILHITNILKAVDPKNLLKQGYSILFAEKEVFVINSICKLKKGQKAKLLLSDGEALITINEVNP
RE
>Mature_481_residues
TQAIKLNLESMFPFIYLQGEISNFKEQSSGHFYFSLKDATAQISAVMFKAEASLLKTPPKGGDHVMIKGEISVYPPKGNY
QLIIRELSYVGIGELLQKLEQLKIKLHQKGWFKAIHKKPIPRFPKKIGVITSPTGAVIQDILQILTRRFSGFHLILNPVK
VQGEGAAKEIARAIEQFNRYQLVDVLIVGRGGGSLEDLWPFNEEIVAEAIYNSQIPIISAVGHETDHCIADYVADIRAPT
PSAAAEIVISEKNQQLEHLKTLRRRIQQAIQNLIQSGHYRLKGFSKHLFITHPHVITEWRMQKLDDLKEDLSNQLKQIIT
FKKHQLESFARQTQLLKPSNQIIHLRKHLRDWNGIFSRKMQDLLLQNKKKIEQIEYRLKQQWTYLIGQKKYLFKGKDYRI
KNNQLIRDRILSSKQKILHITNILKAVDPKNLLKQGYSILFAEKEVFVINSICKLKKGQKAKLLLSDGEALITINEVNPR
E

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=480, Percent_Identity=35.625, Blast_Score=286, Evalue=3e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579 [H]

Pfam domain/function: PF02601 Exonuc_VII_L [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 55443; Mature: 55312

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQAIKLNLESMFPFIYLQGEISNFKEQSSGHFYFSLKDATAQISAVMFKAEASLLKTPP
CCCEEEEEHHHHCCEEEEECCHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCC
KGGDHVMIKGEISVYPPKGNYQLIIRELSYVGIGELLQKLEQLKIKLHQKGWFKAIHKKP
CCCCEEEEEEEEEEECCCCCCEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IPRFPKKIGVITSPTGAVIQDILQILTRRFSGFHLILNPVKVQGEGAAKEIARAIEQFNR
CCCCHHHCCCEECCCHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCHHHHHHHHHHHHCC
YQLVDVLIVGRGGGSLEDLWPFNEEIVAEAIYNSQIPIISAVGHETDHCIADYVADIRAP
EEEEEEEEEECCCCCCHHCCCCCHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCC
TPSAAAEIVISEKNQQLEHLKTLRRRIQQAIQNLIQSGHYRLKGFSKHLFITHPHVITEW
CCCHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEECCHHHHHH
RMQKLDDLKEDLSNQLKQIITFKKHQLESFARQTQLLKPSNQIIHLRKHLRDWNGIFSRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
MQDLLLQNKKKIEQIEYRLKQQWTYLIGQKKYLFKGKDYRIKNNQLIRDRILSSKQKILH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEECCCCHHHHHHHHHHHHHHH
ITNILKAVDPKNLLKQGYSILFAEKEVFVINSICKLKKGQKAKLLLSDGEALITINEVNP
HHHHHHHCCHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCEEEEEECCCC
RE
CC
>Mature Secondary Structure 
TQAIKLNLESMFPFIYLQGEISNFKEQSSGHFYFSLKDATAQISAVMFKAEASLLKTPP
CCEEEEEHHHHCCEEEEECCHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCC
KGGDHVMIKGEISVYPPKGNYQLIIRELSYVGIGELLQKLEQLKIKLHQKGWFKAIHKKP
CCCCEEEEEEEEEEECCCCCCEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IPRFPKKIGVITSPTGAVIQDILQILTRRFSGFHLILNPVKVQGEGAAKEIARAIEQFNR
CCCCHHHCCCEECCCHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCHHHHHHHHHHHHCC
YQLVDVLIVGRGGGSLEDLWPFNEEIVAEAIYNSQIPIISAVGHETDHCIADYVADIRAP
EEEEEEEEEECCCCCCHHCCCCCHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCC
TPSAAAEIVISEKNQQLEHLKTLRRRIQQAIQNLIQSGHYRLKGFSKHLFITHPHVITEW
CCCHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEECCHHHHHH
RMQKLDDLKEDLSNQLKQIITFKKHQLESFARQTQLLKPSNQIIHLRKHLRDWNGIFSRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
MQDLLLQNKKKIEQIEYRLKQQWTYLIGQKKYLFKGKDYRIKNNQLIRDRILSSKQKILH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEECCCCHHHHHHHHHHHHHHH
ITNILKAVDPKNLLKQGYSILFAEKEVFVINSICKLKKGQKAKLLLSDGEALITINEVNP
HHHHHHHCCHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCEEEEEECCCC
RE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA