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The map label for this gene is tsp [H]

Identifier: 46445880

GI number: 46445880

Start: 344722

End: 346683

Strand: Reverse

Name: tsp [H]

Synonym: pc0246

Alternate gene names: 46445880

Gene position: 346683-344722 (Counterclockwise)

Preceding gene: 46445882

Following gene: 46445879

Centisome position: 14.36

GC content: 34.05

Gene sequence:

>1962_bases
ATGTACAAATTTTTAATTTGTTTAATTTGTTTAACAACTTTTGTTTTGGAAGCCAAATCACCTGATTTGAGTCCTAAGGA
AGTCACGTTTAAAGCAAACGAAATTATGAAAGCTCATGCTTCGCAAAAACAACTTTCCCCCACTCTTACTCGTCGAATTT
TAAATAACTATTTAGAAAATTTAGATCCTAATAAAACTTACTTCATTGAATCAGATATTTATGAATGGACTCATCCAACA
GATGAACTCCTCACAAACATTATTGATGATTACAATAACAGTAATTTTTCTACTTTTGAAAGTATTCATACTGCTCTAAT
TAAAGCTATTTTAAAACGCCGTCAACTAGAAAATAAAATAGACTATCAAAGCTTGCCTAAAAATGTTCGAGCAGAAGAAT
TTAAAGATATTCCATGGGTTCAGACTGAAGAAGAGCTTATTGAACGTTTAAAACGCATACGAGCTTTACAAATTGAAACT
GCAGCAAAATTAAACGATCATATGAAGGAAAATGCTCTTCAAAGAATCGGCAAACGACAAGCAAAATACGAAGAAGAGGC
ATTAAATCCAAAAGAACAAGAAAAGCAACCTTTAATCTTATCTAACGTTTTAAAAGCCACAGCATCTGCTTTAGACGCCC
ATACAGCTTATTTTACACCTGGTGAGGCTGCACAATTTATGATTAATGTTCAACAGCGTTTATTCGGAATTGGCGCTCAA
TTGCGTGATGACATTAATGGATTTACTGTAATAAAAATTATTGAGGGTGGCCCCGCAGCCTTAGGTAAAGAACTTAAATT
AAAAGATCGCATTGTTGCAGTCAATGGGGAACCTGTTGTCGGAATGGATATTACAGACGCAGTTGATTTAATTCGAGGGG
AAGAACATACTCCCGTTATTTTGACAGTCATTCGAGAAACGACAAGTACTGCCGGTGAAAAAACTGAAGAAAAATTGGAT
GTGACTATTTTAAGAGGAGAGGTTATTTTAAAAGAAAGTCGTTTCAAAAGTTCTTACGAACCTTATGGAAATGGGATAAT
CGGTTATTTAAAATTATACTCTTTCTATCAGGATCGAGATAGTTCATCCGCAACAGATTTGGAAGAAGAAATTAACAAAC
TTAAAAAGAATCAAAACATGTTTGGTCTTATCCTTGATTTAAGGTATAATTCAGGAGGCCTTTTATCTCAAGCTGTTGCC
GTAACAAGTTTATTTATTACTAAAGGGATTGTAGTCTCCATTAAAGATGAAAACGGGAAAATTCAACATTTAAGAGACTT
AGATGGAACATCAACTTGGGATGGCCCACTCATTATTTTGGTGAATCGCATGAGTGCTTCAGCCTCAGAAATTGTGGCGC
AAACACTACAAGACTACGGTAGAGCAATCATTGTTGGAGATGACCATACATATGGAAAGGGATCGTATCAAACATTCACT
TTGACAACAACCGAACACGAACAAGTCAATCCCCAAGGGGAATATAAAGTCACAAGAGGGCGTTATTATACCGTTTCTGG
TAAAACCCCCCAATTATCAGGTGTATTATCTGACATTCCTATACCAGGTGTATTATCAGAGTCAGAAATTGGAGAGAAGT
ACACCAAATATCCTCTTGAAAACGATCACATCAAAGCAAATTTTGATGATGATCTTTCGGATGTTCCCTTTTTACAGCGA
GATAAAATTCGTAAGTTGTATAAATTTGGTCTTCAAGAGAAGTTAGACACTTATCATCCATATTTTGAAGTATTAAAAAA
GAATTCTTCCAAACGCTTAGAAAATGACCCTAATTATCAAAATATGCTTAAAGAAATAAGAAAGAAGGAAAATAGTGATA
TAGAAAGCATGGAAGACTTTGGTCAAAATGATTTACAATTAGAAGAAGCTTATAAAATCATGAAAGACTTATTAATTATG
ATGCAAGAAAAAGGAATTCCTCTTATTTCTTCAAAATTATAG

Upstream 100 bases:

>100_bases
TTTCTACAAGAATAATCATCCAAAACTCGCCTAATAATAAGTTTTTGGTTATGATTAAAACTTTATCTCCGGCTTATCTT
AAAAGATTGAGGAAATTTTA

Downstream 100 bases:

>100_bases
GAAAGTTCTTTTTAAATATAGAAACTTAATAAGATTGCAAAAAAACAAAATCGTTTATAAACATTTTATTCATTACTAAA
AAGATATTTTATGCGCGTTA

Product: putative carboxy-terminal (= tail-specific) proteinase

Products: NA

Alternate protein names: C-terminal-processing peptidase; PRC protein; Protease Re [H]

Number of amino acids: Translated: 653; Mature: 653

Protein sequence:

>653_residues
MYKFLICLICLTTFVLEAKSPDLSPKEVTFKANEIMKAHASQKQLSPTLTRRILNNYLENLDPNKTYFIESDIYEWTHPT
DELLTNIIDDYNNSNFSTFESIHTALIKAILKRRQLENKIDYQSLPKNVRAEEFKDIPWVQTEEELIERLKRIRALQIET
AAKLNDHMKENALQRIGKRQAKYEEEALNPKEQEKQPLILSNVLKATASALDAHTAYFTPGEAAQFMINVQQRLFGIGAQ
LRDDINGFTVIKIIEGGPAALGKELKLKDRIVAVNGEPVVGMDITDAVDLIRGEEHTPVILTVIRETTSTAGEKTEEKLD
VTILRGEVILKESRFKSSYEPYGNGIIGYLKLYSFYQDRDSSSATDLEEEINKLKKNQNMFGLILDLRYNSGGLLSQAVA
VTSLFITKGIVVSIKDENGKIQHLRDLDGTSTWDGPLIILVNRMSASASEIVAQTLQDYGRAIIVGDDHTYGKGSYQTFT
LTTTEHEQVNPQGEYKVTRGRYYTVSGKTPQLSGVLSDIPIPGVLSESEIGEKYTKYPLENDHIKANFDDDLSDVPFLQR
DKIRKLYKFGLQEKLDTYHPYFEVLKKNSSKRLENDPNYQNMLKEIRKKENSDIESMEDFGQNDLQLEEAYKIMKDLLIM
MQEKGIPLISSKL

Sequences:

>Translated_653_residues
MYKFLICLICLTTFVLEAKSPDLSPKEVTFKANEIMKAHASQKQLSPTLTRRILNNYLENLDPNKTYFIESDIYEWTHPT
DELLTNIIDDYNNSNFSTFESIHTALIKAILKRRQLENKIDYQSLPKNVRAEEFKDIPWVQTEEELIERLKRIRALQIET
AAKLNDHMKENALQRIGKRQAKYEEEALNPKEQEKQPLILSNVLKATASALDAHTAYFTPGEAAQFMINVQQRLFGIGAQ
LRDDINGFTVIKIIEGGPAALGKELKLKDRIVAVNGEPVVGMDITDAVDLIRGEEHTPVILTVIRETTSTAGEKTEEKLD
VTILRGEVILKESRFKSSYEPYGNGIIGYLKLYSFYQDRDSSSATDLEEEINKLKKNQNMFGLILDLRYNSGGLLSQAVA
VTSLFITKGIVVSIKDENGKIQHLRDLDGTSTWDGPLIILVNRMSASASEIVAQTLQDYGRAIIVGDDHTYGKGSYQTFT
LTTTEHEQVNPQGEYKVTRGRYYTVSGKTPQLSGVLSDIPIPGVLSESEIGEKYTKYPLENDHIKANFDDDLSDVPFLQR
DKIRKLYKFGLQEKLDTYHPYFEVLKKNSSKRLENDPNYQNMLKEIRKKENSDIESMEDFGQNDLQLEEAYKIMKDLLIM
MQEKGIPLISSKL
>Mature_653_residues
MYKFLICLICLTTFVLEAKSPDLSPKEVTFKANEIMKAHASQKQLSPTLTRRILNNYLENLDPNKTYFIESDIYEWTHPT
DELLTNIIDDYNNSNFSTFESIHTALIKAILKRRQLENKIDYQSLPKNVRAEEFKDIPWVQTEEELIERLKRIRALQIET
AAKLNDHMKENALQRIGKRQAKYEEEALNPKEQEKQPLILSNVLKATASALDAHTAYFTPGEAAQFMINVQQRLFGIGAQ
LRDDINGFTVIKIIEGGPAALGKELKLKDRIVAVNGEPVVGMDITDAVDLIRGEEHTPVILTVIRETTSTAGEKTEEKLD
VTILRGEVILKESRFKSSYEPYGNGIIGYLKLYSFYQDRDSSSATDLEEEINKLKKNQNMFGLILDLRYNSGGLLSQAVA
VTSLFITKGIVVSIKDENGKIQHLRDLDGTSTWDGPLIILVNRMSASASEIVAQTLQDYGRAIIVGDDHTYGKGSYQTFT
LTTTEHEQVNPQGEYKVTRGRYYTVSGKTPQLSGVLSDIPIPGVLSESEIGEKYTKYPLENDHIKANFDDDLSDVPFLQR
DKIRKLYKFGLQEKLDTYHPYFEVLKKNSSKRLENDPNYQNMLKEIRKKENSDIESMEDFGQNDLQLEEAYKIMKDLLIM
MQEKGIPLISSKL

Specific function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses [H]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=591, Percent_Identity=30.1184433164129, Blast_Score=218, Evalue=7e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR020992 [H]

Pfam domain/function: PF11818 DUF3340; PF00595 PDZ; PF03572 Peptidase_S41 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 74309; Mature: 74309

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKFLICLICLTTFVLEAKSPDLSPKEVTFKANEIMKAHASQKQLSPTLTRRILNNYLEN
CHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
LDPNKTYFIESDIYEWTHPTDELLTNIIDDYNNSNFSTFESIHTALIKAILKRRQLENKI
CCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
DYQSLPKNVRAEEFKDIPWVQTEEELIERLKRIRALQIETAAKLNDHMKENALQRIGKRQ
CHHHCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKYEEEALNPKEQEKQPLILSNVLKATASALDAHTAYFTPGEAAQFMINVQQRLFGIGAQ
HHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHCCHH
LRDDINGFTVIKIIEGGPAALGKELKLKDRIVAVNGEPVVGMDITDAVDLIRGEEHTPVI
HHHCCCCEEEEEEECCCCHHHCCCCEECCEEEEECCCCEECCCHHHHHHHHCCCCCCCEE
LTVIRETTSTAGEKTEEKLDVTILRGEVILKESRFKSSYEPYGNGIIGYLKLYSFYQDRD
EEEEHHHHHCCCCCHHHHEEEEEEECEEEEEHHHCCCCCCCCCCCHHHHHHHHHHHHCCC
SSSATDLEEEINKLKKNQNMFGLILDLRYNSGGLLSQAVAVTSLFITKGIVVSIKDENGK
CCCCCHHHHHHHHHHHCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHCCEEEEEECCCCC
IQHLRDLDGTSTWDGPLIILVNRMSASASEIVAQTLQDYGRAIIVGDDHTYGKGSYQTFT
EEHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEE
LTTTEHEQVNPQGEYKVTRGRYYTVSGKTPQLSGVLSDIPIPGVLSESEIGEKYTKYPLE
EEECCCCCCCCCCCEEEECCEEEEECCCCCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCC
NDHIKANFDDDLSDVPFLQRDKIRKLYKFGLQEKLDTYHPYFEVLKKNSSKRLENDPNYQ
CCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
NMLKEIRKKENSDIESMEDFGQNDLQLEEAYKIMKDLLIMMQEKGIPLISSKL
HHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MYKFLICLICLTTFVLEAKSPDLSPKEVTFKANEIMKAHASQKQLSPTLTRRILNNYLEN
CHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
LDPNKTYFIESDIYEWTHPTDELLTNIIDDYNNSNFSTFESIHTALIKAILKRRQLENKI
CCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
DYQSLPKNVRAEEFKDIPWVQTEEELIERLKRIRALQIETAAKLNDHMKENALQRIGKRQ
CHHHCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKYEEEALNPKEQEKQPLILSNVLKATASALDAHTAYFTPGEAAQFMINVQQRLFGIGAQ
HHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHCCHH
LRDDINGFTVIKIIEGGPAALGKELKLKDRIVAVNGEPVVGMDITDAVDLIRGEEHTPVI
HHHCCCCEEEEEEECCCCHHHCCCCEECCEEEEECCCCEECCCHHHHHHHHCCCCCCCEE
LTVIRETTSTAGEKTEEKLDVTILRGEVILKESRFKSSYEPYGNGIIGYLKLYSFYQDRD
EEEEHHHHHCCCCCHHHHEEEEEEECEEEEEHHHCCCCCCCCCCCHHHHHHHHHHHHCCC
SSSATDLEEEINKLKKNQNMFGLILDLRYNSGGLLSQAVAVTSLFITKGIVVSIKDENGK
CCCCCHHHHHHHHHHHCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHCCEEEEEECCCCC
IQHLRDLDGTSTWDGPLIILVNRMSASASEIVAQTLQDYGRAIIVGDDHTYGKGSYQTFT
EEHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEE
LTTTEHEQVNPQGEYKVTRGRYYTVSGKTPQLSGVLSDIPIPGVLSESEIGEKYTKYPLE
EEECCCCCCCCCCCEEEECCEEEEECCCCCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCC
NDHIKANFDDDLSDVPFLQRDKIRKLYKFGLQEKLDTYHPYFEVLKKNSSKRLENDPNYQ
CCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
NMLKEIRKKENSDIESMEDFGQNDLQLEEAYKIMKDLLIMMQEKGIPLISSKL
HHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1856173; 1729701; 9097040; 9278503; 1447154; 10049386; 7499412; 8576225 [H]