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The map label for this gene is dnaQ_2 [H]

Identifier: 46445870

GI number: 46445870

Start: 332959

End: 333708

Strand: Direct

Name: dnaQ_2 [H]

Synonym: pc0236

Alternate gene names: 46445870

Gene position: 332959-333708 (Clockwise)

Preceding gene: 46445869

Following gene: 46445871

Centisome position: 13.79

GC content: 33.73

Gene sequence:

>750_bases
ATGCCCGATATAGAAAAAAATAAATTTATTTGCATTGATTGTGAAACAACTGGTTTAGATCCTCAACAAGATCGTATTAT
TGAAGTAGCTGTCATGTGTTTTGACGGGAACCAAGTTTATGCACAAATGGAAAGCCTTATTAATCCTGAATGTCCGATAC
CTGAAACGTCTATAGCTATTCATCATATTACTCAAGATATGGTAAAAGATAAACCGACAATTAATCATGTTCTACCGCAA
ATTTTAGAATTGATTAGCGATCATATTATTATTGGTCATGGTGTAGGATTTGATATTGAAATTCTGGCAGTTGCAGCGGA
AAGGCATGGCATCCCTTGCAAAATCAGAAAAAATCGATTTTTAGATACTTTAAGAATGGCCCGACTTTATGGAGAAAGCC
CTGTTAATTCTCTTGAATATTTACGCAAGCACTTTAATATTCCGCTTGAAGGAGCTCATCGTGCCATGAGTGACGTAATT
GTCAATAAAGAAGTATTTAAACATTTATCGAAGCGTTATCGAACTACAGAACAACTTTTTGAAGTTTTATCAAAGCCAAT
TTTGATGAACACAATGCCTCTTGGTAAACATAAAGGACGGCTTCTTAAAGAAATTCCCTTGCAATATTTACAATGGGTTT
GCAATAAAGATTTTGATCAAGATTTGCTTTTTTCTGTACGAACCGAGTTAAAAAGACGTAAACATGGAAATCAGTTTAAT
CAATCCAGTAATCCTTTCTTAAAACTTTAA

Upstream 100 bases:

>100_bases
ACCACCTTTATTATTCAGTCCCTAAAAATCGGGGTAGAAAAGAGCTCATGATAATGATTCAAGATGCTTTGAATGATGAA
GATAAACAAGAATAGAGACT

Downstream 100 bases:

>100_bases
TGCATAGGGGTAGACATGGGACAATTTAATCAAACTGAAAAAGGATCATTTGAAATTAAAGTTGCCTTGGCAGAGATGTT
GAAAGGAGGAGTGATCATGG

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: PolIII [H]

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MPDIEKNKFICIDCETTGLDPQQDRIIEVAVMCFDGNQVYAQMESLINPECPIPETSIAIHHITQDMVKDKPTINHVLPQ
ILELISDHIIIGHGVGFDIEILAVAAERHGIPCKIRKNRFLDTLRMARLYGESPVNSLEYLRKHFNIPLEGAHRAMSDVI
VNKEVFKHLSKRYRTTEQLFEVLSKPILMNTMPLGKHKGRLLKEIPLQYLQWVCNKDFDQDLLFSVRTELKRRKHGNQFN
QSSNPFLKL

Sequences:

>Translated_249_residues
MPDIEKNKFICIDCETTGLDPQQDRIIEVAVMCFDGNQVYAQMESLINPECPIPETSIAIHHITQDMVKDKPTINHVLPQ
ILELISDHIIIGHGVGFDIEILAVAAERHGIPCKIRKNRFLDTLRMARLYGESPVNSLEYLRKHFNIPLEGAHRAMSDVI
VNKEVFKHLSKRYRTTEQLFEVLSKPILMNTMPLGKHKGRLLKEIPLQYLQWVCNKDFDQDLLFSVRTELKRRKHGNQFN
QSSNPFLKL
>Mature_248_residues
PDIEKNKFICIDCETTGLDPQQDRIIEVAVMCFDGNQVYAQMESLINPECPIPETSIAIHHITQDMVKDKPTINHVLPQI
LELISDHIIIGHGVGFDIEILAVAAERHGIPCKIRKNRFLDTLRMARLYGESPVNSLEYLRKHFNIPLEGAHRAMSDVIV
NKEVFKHLSKRYRTTEQLFEVLSKPILMNTMPLGKHKGRLLKEIPLQYLQWVCNKDFDQDLLFSVRTELKRRKHGNQFNQ
SSNPFLKL

Specific function: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain [H]

Homologues:

Organism=Escherichia coli, GI1788149, Length=213, Percent_Identity=28.6384976525822, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011708
- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR006308
- InterPro:   IPR012337 [H]

Pfam domain/function: PF07733 DNA_pol3_alpha; PF00929 Exonuc_X-T; PF02811 PHP; PF01336 tRNA_anti [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 28779; Mature: 28648

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDIEKNKFICIDCETTGLDPQQDRIIEVAVMCFDGNQVYAQMESLINPECPIPETSIAI
CCCCCCCCEEEEECCCCCCCCCHHHEEEEEEEEECCCHHHHHHHHHCCCCCCCCCCHHHH
HHITQDMVKDKPTINHVLPQILELISDHIIIGHGVGFDIEILAVAAERHGIPCKIRKNRF
HHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEECCCCCCEEEEEEEHHHCCCCEEECHHHH
LDTLRMARLYGESPVNSLEYLRKHFNIPLEGAHRAMSDVIVNKEVFKHLSKRYRTTEQLF
HHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
EVLSKPILMNTMPLGKHKGRLLKEIPLQYLQWVCNKDFDQDLLFSVRTELKRRKHGNQFN
HHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCC
QSSNPFLKL
CCCCCCEEC
>Mature Secondary Structure 
PDIEKNKFICIDCETTGLDPQQDRIIEVAVMCFDGNQVYAQMESLINPECPIPETSIAI
CCCCCCCEEEEECCCCCCCCCHHHEEEEEEEEECCCHHHHHHHHHCCCCCCCCCCHHHH
HHITQDMVKDKPTINHVLPQILELISDHIIIGHGVGFDIEILAVAAERHGIPCKIRKNRF
HHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEECCCCCCEEEEEEEHHHCCCCEEECHHHH
LDTLRMARLYGESPVNSLEYLRKHFNIPLEGAHRAMSDVIVNKEVFKHLSKRYRTTEQLF
HHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
EVLSKPILMNTMPLGKHKGRLLKEIPLQYLQWVCNKDFDQDLLFSVRTELKRRKHGNQFN
HHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCC
QSSNPFLKL
CCCCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA