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The map label for this gene is rodA [H]

Identifier: 46445800

GI number: 46445800

Start: 245054

End: 246190

Strand: Direct

Name: rodA [H]

Synonym: pc0166

Alternate gene names: 46445800

Gene position: 245054-246190 (Clockwise)

Preceding gene: 46445797

Following gene: 46445801

Centisome position: 10.15

GC content: 37.73

Gene sequence:

>1137_bases
ATGTGGAGTCCTCGTTATCTTGCTCGATTAGACTTTAGGGTTATTCCCGTTATTTTAAGTCTGATGATTATCAGCTTGTT
AGTTGTCTCATCTTATACAATTGACCCTTCAACAGATCATGCGGAAGAGTTATTTGTCACACCTATCGTAAAATCTCAAT
TTCAATGGTTCGCAATTGGAGTTGTTGTTTATTTCTTTTTTGCGGGCTTTGACTATCGTAAATTACGAGAATGGACCTGG
ATTTTATACGTTTTAGTATTAATTTCTTTAGTAGGACTTTTTTTTACTGATTCGATTCAAAAAGTGAATCGCTGGTATCG
TATTCCTTTTATTAATATCAGTTTTCAGCCTTCAGAGTATGCGAAGTTTGTCGTTGTGATTACTTTAAGCTGGTTTTTAG
AAAGACGTAGATCAGTCGCCGATTCTTGGGGAACTGCTTTTTATGCGTCGATTATCGTGGGAATTCCATTTATCCTCATT
TTAAAACAACCTGATTTGGGAACTGCTTTAGTTTTATTTCCCATTACACTTGTGATGTTTTATTTTGGAGATTTAAGGCC
TTCGATTATTAAAGCAATGACAATTTGCGGAGGACTGGGATTATGTCTTGTTGCAATGATTTTTTTAGGGGTTCTACCCC
ATGAAACATTGCGTCCTTATGCAACAAAAGTACTAAAAGATTATCAATTCGATCGACTTGATCCTGCCACTCATCATCAA
AAAGCGGCTGCTACTGCTATTGCATTGGGGGGAATCACAGGGACGGGATGGAGAAAAAGTGAGTTTAGCGGTAGGGGGTG
GCTTCCAGCCCCTTATACAGATTCTGTATTTCCAGCTTTCGGGGAAGAGTTTGGTTTGCTGGGATTGCTGTTATTAATGG
TTCTTTACTACGCTTTGATTTATTTTAGTTTTCAAGTAAGTGCAGTTGCTAAAGATCCATTTGGGAGGCTTTTATCAGCT
GGGGTGACTGTTTATTTAGCGATGCACATATTAGTCAATATTGGAATGATGTGTGGATTTCTTCCAATTACAGGGGTACC
TCTTGTTTTGGTGACTTATGGTGGCTCTTCTATTCTTTCCACGATGATGGCTTTAGGAATTTTACAAAGTATTTATAGCC
GAAGGTTTATGTTTTAA

Upstream 100 bases:

>100_bases
TGTTTAATCTAGCATTTTATCATAATAAATGATTTGCCTTGTGGATTCACCTATTTTCGTGATATCTTACTACTTTATCG
ATTTATATAGTGATATTTAA

Downstream 100 bases:

>100_bases
TAAATGATAACTATTTGACTGACAAATTTATTTTTAATTTTAGAGGTTCAATGACTCAACCTGAATTTATTTTTACCCCA
GGTTTATGGCTAGGAGAAGG

Product: cell shape (rod)-determining protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MWSPRYLARLDFRVIPVILSLMIISLLVVSSYTIDPSTDHAEELFVTPIVKSQFQWFAIGVVVYFFFAGFDYRKLREWTW
ILYVLVLISLVGLFFTDSIQKVNRWYRIPFINISFQPSEYAKFVVVITLSWFLERRRSVADSWGTAFYASIIVGIPFILI
LKQPDLGTALVLFPITLVMFYFGDLRPSIIKAMTICGGLGLCLVAMIFLGVLPHETLRPYATKVLKDYQFDRLDPATHHQ
KAAATAIALGGITGTGWRKSEFSGRGWLPAPYTDSVFPAFGEEFGLLGLLLLMVLYYALIYFSFQVSAVAKDPFGRLLSA
GVTVYLAMHILVNIGMMCGFLPITGVPLVLVTYGGSSILSTMMALGILQSIYSRRFMF

Sequences:

>Translated_378_residues
MWSPRYLARLDFRVIPVILSLMIISLLVVSSYTIDPSTDHAEELFVTPIVKSQFQWFAIGVVVYFFFAGFDYRKLREWTW
ILYVLVLISLVGLFFTDSIQKVNRWYRIPFINISFQPSEYAKFVVVITLSWFLERRRSVADSWGTAFYASIIVGIPFILI
LKQPDLGTALVLFPITLVMFYFGDLRPSIIKAMTICGGLGLCLVAMIFLGVLPHETLRPYATKVLKDYQFDRLDPATHHQ
KAAATAIALGGITGTGWRKSEFSGRGWLPAPYTDSVFPAFGEEFGLLGLLLLMVLYYALIYFSFQVSAVAKDPFGRLLSA
GVTVYLAMHILVNIGMMCGFLPITGVPLVLVTYGGSSILSTMMALGILQSIYSRRFMF
>Mature_378_residues
MWSPRYLARLDFRVIPVILSLMIISLLVVSSYTIDPSTDHAEELFVTPIVKSQFQWFAIGVVVYFFFAGFDYRKLREWTW
ILYVLVLISLVGLFFTDSIQKVNRWYRIPFINISFQPSEYAKFVVVITLSWFLERRRSVADSWGTAFYASIIVGIPFILI
LKQPDLGTALVLFPITLVMFYFGDLRPSIIKAMTICGGLGLCLVAMIFLGVLPHETLRPYATKVLKDYQFDRLDPATHHQ
KAAATAIALGGITGTGWRKSEFSGRGWLPAPYTDSVFPAFGEEFGLLGLLLLMVLYYALIYFSFQVSAVAKDPFGRLLSA
GVTVYLAMHILVNIGMMCGFLPITGVPLVLVTYGGSSILSTMMALGILQSIYSRRFMF

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=334, Percent_Identity=32.3353293413174, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1786277, Length=305, Percent_Identity=28.1967213114754, Blast_Score=85, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 42567; Mature: 42567

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS01082 RIBOSOMAL_L7AE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWSPRYLARLDFRVIPVILSLMIISLLVVSSYTIDPSTDHAEELFVTPIVKSQFQWFAIG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VVVYFFFAGFDYRKLREWTWILYVLVLISLVGLFFTDSIQKVNRWYRIPFINISFQPSEY
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECEEEEEEECCHHH
AKFVVVITLSWFLERRRSVADSWGTAFYASIIVGIPFILILKQPDLGTALVLFPITLVMF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHH
YFGDLRPSIIKAMTICGGLGLCLVAMIFLGVLPHETLRPYATKVLKDYQFDRLDPATHHQ
HHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHH
KAAATAIALGGITGTGWRKSEFSGRGWLPAPYTDSVFPAFGEEFGLLGLLLLMVLYYALI
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
YFSFQVSAVAKDPFGRLLSAGVTVYLAMHILVNIGMMCGFLPITGVPLVLVTYGGSSILS
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHH
TMMALGILQSIYSRRFMF
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MWSPRYLARLDFRVIPVILSLMIISLLVVSSYTIDPSTDHAEELFVTPIVKSQFQWFAIG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VVVYFFFAGFDYRKLREWTWILYVLVLISLVGLFFTDSIQKVNRWYRIPFINISFQPSEY
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECEEEEEEECCHHH
AKFVVVITLSWFLERRRSVADSWGTAFYASIIVGIPFILILKQPDLGTALVLFPITLVMF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHH
YFGDLRPSIIKAMTICGGLGLCLVAMIFLGVLPHETLRPYATKVLKDYQFDRLDPATHHQ
HHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHH
KAAATAIALGGITGTGWRKSEFSGRGWLPAPYTDSVFPAFGEEFGLLGLLLLMVLYYALI
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
YFSFQVSAVAKDPFGRLLSAGVTVYLAMHILVNIGMMCGFLPITGVPLVLVTYGGSSILS
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHH
TMMALGILQSIYSRRFMF
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]