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The map label for this gene is nqrA [H]

Identifier: 46445729

GI number: 46445729

Start: 157177

End: 158577

Strand: Direct

Name: nqrA [H]

Synonym: pc0095

Alternate gene names: 46445729

Gene position: 157177-158577 (Clockwise)

Preceding gene: 46445728

Following gene: 46445732

Centisome position: 6.51

GC content: 36.62

Gene sequence:

>1401_bases
ATGAAATTCATGAGCCATATAAAAATCACTAAAGGATTAGATATTCCCATCAAAGGAAAACCGGAAGGAATTCCTAAACT
TTTAGTGGCGAGTGGAGAAGCACATGCATTGAAAAATCCTGTTCAAATTGCTCTTGATTTCAATCCTTTTGAAGATTTGC
GTTTTAAATTATTGGTTCAAGTTGGTGAAAAAGTAAAGTTAGGACAGCCTTTAGCAGAAGATAAGGATACACCGGGGCGC
TATTTTGTTTCTCCAGCAGGAGGGGTCGTTCGGGAAATTCGAAGGGGGCTTAAAAGAAGACTTCTCGATATTGTGGTAGA
AACTTCTAATCACGAAGAGGTTAAAAAACATCCTCTTTTAAGTTTAAATACAGCATCTAGAGAAGAACTTGTTGGGGCTT
TAATGACAGGAGGGCTATTTGCTCGGATTCGGCAAAGACCATTCAATTTTTTAGCAAATCCTCAGCAAATTCCTCGTAGT
ATTTTTGTTAAGGCTGTGGAATCAGCTCCCTTTACTCCTCCACCAGACATGCAGGTAAAAGGATATGAGAAAGAATTTCA
AGAAGGTTTAAAAACGTTAGCAAAATTAACAAATGGAGCGGTTCATCTTATTTATCAAAAAGATAATTTAGAGCCAGCTT
TTTTTAATGCGGAAGGTGTTCAAAAGCATACTGTAGAAGGGCCTCATCCTATTGGAAATGTTTCTTTACACATTCAACAT
ATTGATCCTATTTATTCTCCTCAAGATGTTATTTGGACCTTAGATGTACATACTGTTGTTGCAATTGGTTATTTTTTACT
TCGCGGTGAATATTTGGTTAATCGGGTGATAAGTATAGCTGGGACAGGTATTTTAGAAGGTAAGACAGGATTTTTTCAAG
TTCGCGAAGGATTCCCTATTTCTTCCCTGATTGCAGGTCGCGTTGCTAAAGGGGTGGTGAGGTTTATTTCTGGTAATCCG
TTAAATGGGCGTCAAGTATCCGCAGAAGATTTCCTTGGTTATTATGATTATGTGTTTTGCGCTATTCCTGAAAACATCAA
GCGGGAATTTATGCACTTCTTCCGTTTAGGAATTGATAAATATACGTTTAGTAAAACGTATTTATCAGGTCATTTAGATA
ACTCTCAACGGGAATATGATTTTACAACAAGTCAACATGGTGAAGAGCGTGCTTTTATCGATAGTACTTTATACGATAAA
GTGAATCCTCTTTCTGTTTCAATTATGCATCTTGTAAAAGCAGTTTTAGCAGAAGATTATGACCTTGCAGTGGAATTAGG
TTTATTAGAAGTTGATGCTGAGGATTTTGATTTGGCTACATTTGTAGATCCTTCTAAAATTGAAATGAACCAAATTATTC
GACAAGGATTAAAGCGTTACGCCGCAGATATTCTTAAGTAA

Upstream 100 bases:

>100_bases
AAGTAAAGACAAAGCAAAGTAAAAATTGAGTATGACGTTGCGCTTGCTTAAAACCCATTTTTCAATTAATTTTTGTTTTT
TAATCGAATTTTAAGGATGA

Downstream 100 bases:

>100_bases
TATTTTTGGTTTTGGATTGACGGGGGCGAAGTCTAGGAATTGCGTTAAGAAGCTCTTTTGTATAAGTACTTTGGGGATTT
TCAAAAATTTGTATATTGGA

Product: Na(+)-translocating NADH-quinone reductase subunit A

Products: NA

Alternate protein names: Na(+)-NQR subunit A; Na(+)-translocating NQR subunit A; NQR complex subunit A; NQR-1 subunit A [H]

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MKFMSHIKITKGLDIPIKGKPEGIPKLLVASGEAHALKNPVQIALDFNPFEDLRFKLLVQVGEKVKLGQPLAEDKDTPGR
YFVSPAGGVVREIRRGLKRRLLDIVVETSNHEEVKKHPLLSLNTASREELVGALMTGGLFARIRQRPFNFLANPQQIPRS
IFVKAVESAPFTPPPDMQVKGYEKEFQEGLKTLAKLTNGAVHLIYQKDNLEPAFFNAEGVQKHTVEGPHPIGNVSLHIQH
IDPIYSPQDVIWTLDVHTVVAIGYFLLRGEYLVNRVISIAGTGILEGKTGFFQVREGFPISSLIAGRVAKGVVRFISGNP
LNGRQVSAEDFLGYYDYVFCAIPENIKREFMHFFRLGIDKYTFSKTYLSGHLDNSQREYDFTTSQHGEERAFIDSTLYDK
VNPLSVSIMHLVKAVLAEDYDLAVELGLLEVDAEDFDLATFVDPSKIEMNQIIRQGLKRYAADILK

Sequences:

>Translated_466_residues
MKFMSHIKITKGLDIPIKGKPEGIPKLLVASGEAHALKNPVQIALDFNPFEDLRFKLLVQVGEKVKLGQPLAEDKDTPGR
YFVSPAGGVVREIRRGLKRRLLDIVVETSNHEEVKKHPLLSLNTASREELVGALMTGGLFARIRQRPFNFLANPQQIPRS
IFVKAVESAPFTPPPDMQVKGYEKEFQEGLKTLAKLTNGAVHLIYQKDNLEPAFFNAEGVQKHTVEGPHPIGNVSLHIQH
IDPIYSPQDVIWTLDVHTVVAIGYFLLRGEYLVNRVISIAGTGILEGKTGFFQVREGFPISSLIAGRVAKGVVRFISGNP
LNGRQVSAEDFLGYYDYVFCAIPENIKREFMHFFRLGIDKYTFSKTYLSGHLDNSQREYDFTTSQHGEERAFIDSTLYDK
VNPLSVSIMHLVKAVLAEDYDLAVELGLLEVDAEDFDLATFVDPSKIEMNQIIRQGLKRYAADILK
>Mature_466_residues
MKFMSHIKITKGLDIPIKGKPEGIPKLLVASGEAHALKNPVQIALDFNPFEDLRFKLLVQVGEKVKLGQPLAEDKDTPGR
YFVSPAGGVVREIRRGLKRRLLDIVVETSNHEEVKKHPLLSLNTASREELVGALMTGGLFARIRQRPFNFLANPQQIPRS
IFVKAVESAPFTPPPDMQVKGYEKEFQEGLKTLAKLTNGAVHLIYQKDNLEPAFFNAEGVQKHTVEGPHPIGNVSLHIQH
IDPIYSPQDVIWTLDVHTVVAIGYFLLRGEYLVNRVISIAGTGILEGKTGFFQVREGFPISSLIAGRVAKGVVRFISGNP
LNGRQVSAEDFLGYYDYVFCAIPENIKREFMHFFRLGIDKYTFSKTYLSGHLDNSQREYDFTTSQHGEERAFIDSTLYDK
VNPLSVSIMHLVKAVLAEDYDLAVELGLLEVDAEDFDLATFVDPSKIEMNQIIRQGLKRYAADILK

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG1726

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008703
- InterPro:   IPR022615 [H]

Pfam domain/function: PF05896 NQRA; PF11973 NQRA_SLBB [H]

EC number: NA

Molecular weight: Translated: 52260; Mature: 52260

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFMSHIKITKGLDIPIKGKPEGIPKLLVASGEAHALKNPVQIALDFNPFEDLRFKLLVQ
CCHHHHEEEECCCCCCCCCCCCCCCEEEEECCCHHHCCCCEEEEEECCCHHHHHHHHHHH
VGEKVKLGQPLAEDKDTPGRYFVSPAGGVVREIRRGLKRRLLDIVVETSNHEEVKKHPLL
HCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCE
SLNTASREELVGALMTGGLFARIRQRPFNFLANPQQIPRSIFVKAVESAPFTPPPDMQVK
EECCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
GYEKEFQEGLKTLAKLTNGAVHLIYQKDNLEPAFFNAEGVQKHTVEGPHPIGNVSLHIQH
CCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCEEEEEEE
IDPIYSPQDVIWTLDVHTVVAIGYFLLRGEYLVNRVISIAGTGILEGKTGFFQVREGFPI
CCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEEEECCCCH
SSLIAGRVAKGVVRFISGNPLNGRQVSAEDFLGYYDYVFCAIPENIKREFMHFFRLGIDK
HHHHHHHHHHHHHHHHCCCCCCCCEECHHHHHHHHHEEEEECCHHHHHHHHHHHHHCCCH
YTFSKTYLSGHLDNSQREYDFTTSQHGEERAFIDSTLYDKVNPLSVSIMHLVKAVLAEDY
HEEHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
DLAVELGLLEVDAEDFDLATFVDPSKIEMNQIIRQGLKRYAADILK
CEEEEEEEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKFMSHIKITKGLDIPIKGKPEGIPKLLVASGEAHALKNPVQIALDFNPFEDLRFKLLVQ
CCHHHHEEEECCCCCCCCCCCCCCCEEEEECCCHHHCCCCEEEEEECCCHHHHHHHHHHH
VGEKVKLGQPLAEDKDTPGRYFVSPAGGVVREIRRGLKRRLLDIVVETSNHEEVKKHPLL
HCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCE
SLNTASREELVGALMTGGLFARIRQRPFNFLANPQQIPRSIFVKAVESAPFTPPPDMQVK
EECCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
GYEKEFQEGLKTLAKLTNGAVHLIYQKDNLEPAFFNAEGVQKHTVEGPHPIGNVSLHIQH
CCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCEEEEEEE
IDPIYSPQDVIWTLDVHTVVAIGYFLLRGEYLVNRVISIAGTGILEGKTGFFQVREGFPI
CCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEEEECCCCH
SSLIAGRVAKGVVRFISGNPLNGRQVSAEDFLGYYDYVFCAIPENIKREFMHFFRLGIDK
HHHHHHHHHHHHHHHHCCCCCCCCEECHHHHHHHHHEEEEECCHHHHHHHHHHHHHCCCH
YTFSKTYLSGHLDNSQREYDFTTSQHGEERAFIDSTLYDKVNPLSVSIMHLVKAVLAEDY
HEEHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
DLAVELGLLEVDAEDFDLATFVDPSKIEMNQIIRQGLKRYAADILK
CEEEEEEEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]