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The map label for this gene is glmU

Identifier: 46445650

GI number: 46445650

Start: 26732

End: 28063

Strand: Reverse

Name: glmU

Synonym: pc0016

Alternate gene names: NA

Gene position: 28063-26732 (Counterclockwise)

Preceding gene: 46445651

Following gene: 46445646

Centisome position: 1.16

GC content: 34.16

Gene sequence:

>1332_bases
ATGCTAGCAAAAAAAGCAAATGATCCTCTTCTAAAATTTTGGACTCTCTTATCAAAACAAGAACAACAAAATTTAACGCT
TCAAATAAAACAAATTAATCGCACTCTTCTCGATCAACAAATAGCTTTAATTAACCCATCTAAATCAGTTGATTCTTTTA
TTGAACCATTTAAAGATTATGCGTTTGCAGGAAATGAAAAGCTGCAATTAAAAGGTAAGCAACTCCTTCAAAACGGAAAG
ATGGGGTGTATTGTTCTCGCAGGTGGGCAAGGAACCAGGCTTTGTTTTGAAGGCCCTAAAGGACTTTTTCCTGTTTCTGT
TATTAAGCATAAGTCATTATTTCAACTTTTAGCAGAAAAAACTGTTGCCGCGAGTAAACAAGTTAACTTTCCTTTATCTC
TCGCCATTATGACTTCACCAAAAAATGATCAAGCAACTAAACAGTTTTTTGTTGAAAATGACTATTGGGGTTTATCTAAA
GGTCAAATTTCATTTTTTTGCCAAAGTACCCTCCCTTTGCTAAATGCAGAAGGGTCTCTATTTTTAGAAACCAAAAGCCG
TATAGCCGAAGGGCCTAATGGCAATGGGCATTGTCTACATGATTTTTATCAATCGGGCTTATACGACGTATGGAAACAAC
GGGGTATTGAATACATTAATATTATCTTAGTGGATAATCCATTGGCAGATCCATTTGATGCAGAATTACTTGGTTTCCAT
CATCAACAAAAAGCTGAAATTACTATTAAATGTACTGAAAAGCACGAACCTCAAGAAAAAGTCGGAATTCTTGTTAAAGA
AAATCACCGAGTAAAAGTGATTGAATATTCTGAATTACCTGATCAGCATAAAAATGCTAGCGAAGCTAACGGTCGTCTTC
AATACTGTTGTGCAAATTTAAGCTTATTTTGTTTTTCCATGTCTTTTATTGAAAATACGCTCCCAAATCACCCCTTTTTG
CCTCTACATAAAGCTTGGAAAGCAGCAAAATTTGTGAACGAGCAAGGAGTTACTACACTGTCTTCCCATCCCATCGCTTG
GAAATTTGAAACTTTCATTTTTGATTGGTTACAATATTCTAAAAAAGTTTTCGCTTTATTATATCCACGTCACCACTGTT
TTGCTCCTTTAAAAAACTTTCAAGGAAATGACTCATTAGAATCTGTTCAAAAAGCACTTATCTATCGTGAAAAAGAAATT
TTAAAGTCGATTACGGGTTTAGAACCTTCTTCAAACTTAATAGAATTAGCAGCTGATTTTTACTATCCGACAGCAGATTT
ATTAAATAAATGGAAAAATCGTTTAGCAAAAACCTTGTATGTAGAACCTTAA

Upstream 100 bases:

>100_bases
CCGGCAGTTTACAAATTCCTGTTTTAATTTTCTTAACAATTGGTATAACTATCTTGAATTAGAAACTAGATCTTTTATTT
CAATAAAATTTTCTTCAATC

Downstream 100 bases:

>100_bases
AAAAGGTGGCAAAATTAGTTTTTTAGTGCACAAAAATTTCATCTATACAAAGCAAAACTTTTGCTAATCATTAACAGACT
TGAATTGGAAGCTCGAAAGT

Product: putative bifunctional protein UDP-N-acetylglucosamine pyrophosphorylase, glucosamine-1-phosphate N-acetyltransferase

Products: diphosphate; UDP-N-acetyl-D-glucosamine

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MLAKKANDPLLKFWTLLSKQEQQNLTLQIKQINRTLLDQQIALINPSKSVDSFIEPFKDYAFAGNEKLQLKGKQLLQNGK
MGCIVLAGGQGTRLCFEGPKGLFPVSVIKHKSLFQLLAEKTVAASKQVNFPLSLAIMTSPKNDQATKQFFVENDYWGLSK
GQISFFCQSTLPLLNAEGSLFLETKSRIAEGPNGNGHCLHDFYQSGLYDVWKQRGIEYINIILVDNPLADPFDAELLGFH
HQQKAEITIKCTEKHEPQEKVGILVKENHRVKVIEYSELPDQHKNASEANGRLQYCCANLSLFCFSMSFIENTLPNHPFL
PLHKAWKAAKFVNEQGVTTLSSHPIAWKFETFIFDWLQYSKKVFALLYPRHHCFAPLKNFQGNDSLESVQKALIYREKEI
LKSITGLEPSSNLIELAADFYYPTADLLNKWKNRLAKTLYVEP

Sequences:

>Translated_443_residues
MLAKKANDPLLKFWTLLSKQEQQNLTLQIKQINRTLLDQQIALINPSKSVDSFIEPFKDYAFAGNEKLQLKGKQLLQNGK
MGCIVLAGGQGTRLCFEGPKGLFPVSVIKHKSLFQLLAEKTVAASKQVNFPLSLAIMTSPKNDQATKQFFVENDYWGLSK
GQISFFCQSTLPLLNAEGSLFLETKSRIAEGPNGNGHCLHDFYQSGLYDVWKQRGIEYINIILVDNPLADPFDAELLGFH
HQQKAEITIKCTEKHEPQEKVGILVKENHRVKVIEYSELPDQHKNASEANGRLQYCCANLSLFCFSMSFIENTLPNHPFL
PLHKAWKAAKFVNEQGVTTLSSHPIAWKFETFIFDWLQYSKKVFALLYPRHHCFAPLKNFQGNDSLESVQKALIYREKEI
LKSITGLEPSSNLIELAADFYYPTADLLNKWKNRLAKTLYVEP
>Mature_443_residues
MLAKKANDPLLKFWTLLSKQEQQNLTLQIKQINRTLLDQQIALINPSKSVDSFIEPFKDYAFAGNEKLQLKGKQLLQNGK
MGCIVLAGGQGTRLCFEGPKGLFPVSVIKHKSLFQLLAEKTVAASKQVNFPLSLAIMTSPKNDQATKQFFVENDYWGLSK
GQISFFCQSTLPLLNAEGSLFLETKSRIAEGPNGNGHCLHDFYQSGLYDVWKQRGIEYINIILVDNPLADPFDAELLGFH
HQQKAEITIKCTEKHEPQEKVGILVKENHRVKVIEYSELPDQHKNASEANGRLQYCCANLSLFCFSMSFIENTLPNHPFL
PLHKAWKAAKFVNEQGVTTLSSHPIAWKFETFIFDWLQYSKKVFALLYPRHHCFAPLKNFQGNDSLESVQKALIYREKEI
LKSITGLEPSSNLIELAADFYYPTADLLNKWKNRLAKTLYVEP

Specific function: Unknown

COG id: COG4284

COG function: function code G; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 1 family [H]

Homologues:

Organism=Homo sapiens, GI156627575, Length=418, Percent_Identity=31.3397129186603, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI187936958, Length=324, Percent_Identity=30.8641975308642, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI48255968, Length=215, Percent_Identity=26.9767441860465, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI48255966, Length=215, Percent_Identity=26.9767441860465, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17552518, Length=420, Percent_Identity=30, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI193206427, Length=332, Percent_Identity=29.8192771084337, Blast_Score=139, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6320100, Length=445, Percent_Identity=29.8876404494382, Blast_Score=164, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24582229, Length=428, Percent_Identity=30.1401869158879, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI19920822, Length=428, Percent_Identity=30.1401869158879, Blast_Score=193, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002618 [H]

Pfam domain/function: PF01704 UDPGP [H]

EC number: 2.7.7.23

Molecular weight: Translated: 50375; Mature: 50375

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAKKANDPLLKFWTLLSKQEQQNLTLQIKQINRTLLDQQIALINPSKSVDSFIEPFKDY
CCCCCCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCEEECCCHHHHHHHHHHHHH
AFAGNEKLQLKGKQLLQNGKMGCIVLAGGQGTRLCFEGPKGLFPVSVIKHKSLFQLLAEK
HCCCCCEEEECHHHHHHCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHH
TVAASKQVNFPLSLAIMTSPKNDQATKQFFVENDYWGLSKGQISFFCQSTLPLLNAEGSL
HHHHCCCCCCCEEEEEEECCCCCCHHHHEEEECCCCCCCCCCEEEEEECCCCEECCCCCE
FLETKSRIAEGPNGNGHCLHDFYQSGLYDVWKQRGIEYINIILVDNPLADPFDAELLGFH
EEEEHHHHCCCCCCCCCCHHHHHHCCHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHCCC
HQQKAEITIKCTEKHEPQEKVGILVKENHRVKVIEYSELPDQHKNASEANGRLQYCCANL
CCCCCEEEEEECCCCCCHHHHCEEEECCCEEEEEEECCCCCCCCCCCCCCCCEEEHHHHH
SLFCFSMSFIENTLPNHPFLPLHKAWKAAKFVNEQGVTTLSSHPIAWKFETFIFDWLQYS
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCEEEHHHHHHHHHHHH
KKVFALLYPRHHCFAPLKNFQGNDSLESVQKALIYREKEILKSITGLEPSSNLIELAADF
HHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
YYPTADLLNKWKNRLAKTLYVEP
CCCCHHHHHHHHHHHHHHEECCC
>Mature Secondary Structure
MLAKKANDPLLKFWTLLSKQEQQNLTLQIKQINRTLLDQQIALINPSKSVDSFIEPFKDY
CCCCCCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCEEECCCHHHHHHHHHHHHH
AFAGNEKLQLKGKQLLQNGKMGCIVLAGGQGTRLCFEGPKGLFPVSVIKHKSLFQLLAEK
HCCCCCEEEECHHHHHHCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHH
TVAASKQVNFPLSLAIMTSPKNDQATKQFFVENDYWGLSKGQISFFCQSTLPLLNAEGSL
HHHHCCCCCCCEEEEEEECCCCCCHHHHEEEECCCCCCCCCCEEEEEECCCCEECCCCCE
FLETKSRIAEGPNGNGHCLHDFYQSGLYDVWKQRGIEYINIILVDNPLADPFDAELLGFH
EEEEHHHHCCCCCCCCCCHHHHHHCCHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHCCC
HQQKAEITIKCTEKHEPQEKVGILVKENHRVKVIEYSELPDQHKNASEANGRLQYCCANL
CCCCCEEEEEECCCCCCHHHHCEEEECCCEEEEEEECCCCCCCCCCCCCCCCEEEHHHHH
SLFCFSMSFIENTLPNHPFLPLHKAWKAAKFVNEQGVTTLSSHPIAWKFETFIFDWLQYS
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCEEEHHHHHHHHHHHH
KKVFALLYPRHHCFAPLKNFQGNDSLESVQKALIYREKEILKSITGLEPSSNLIELAADF
HHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
YYPTADLLNKWKNRLAKTLYVEP
CCCCHHHHHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UTP; N-acetyl-alpha-D-glucosamine 1-phosphate

Specific reaction: UTP + N-acetyl-alpha-D-glucosamine 1-phosphate = diphosphate + UDP-N-acetyl-D-glucosamine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA