Click here to switch to the map view.

The map label for this gene is dnaX [H]

Identifier: 45659308

GI number: 45659308

Start: 4276081

End: 4277013

Strand: Direct

Name: dnaX [H]

Synonym: LIC13497

Alternate gene names: 45659308

Gene position: 4276081-4277013 (Clockwise)

Preceding gene: 45659307

Following gene: NA

Centisome position: 99.97

GC content: 33.01

Gene sequence:

>933_bases
ATGAAATCGTTTCAGTTGGATGAAATTTTAGGACAAGAAGTTGCTCTTACTTTTTTAAAAAGATATATTTCCAAACCAGA
AACCATTCCACCACTTTTAATTTTCCACGGGCCGGACGGAACCGGAAAAGAATCTGCATCCGAACGATTTATCAAAAACG
TATTGTGTTTCGAAGGAACTTCGTGCGGAGTATGTGCTTCTTGTAAATCTTTTATACACAACTCACATCCGGATTATATT
CGTTTTCCAGAAGAAAGCGGTAAAATCATTCCCATCGGAAGTGAAGATAATCCAGAAGAATTTTCGATCCGATGGTTGAT
CCGTTCTCGATTAAATTATCGTCCTCATCTTTCCAAATTTCGTTTTATTGTTTTTCCAGATGCGTCTCTTATTGGAAACG
AAGCAGAAACAGCACTTTTAAAATCCTTAGAAGAAGCGCCTCCGTTTTCTAGATTTATTTTTATCGTAAACAATTTAGAT
AAACTCAAAGAAACAATCGTAAGTAGAGCCATTTGTGTTCCTTTCCAATACCTCAATCAAGAGGATCTTAGAAAAATAAA
TACAAACTTAGGTCTTTCTACATTTCCATTCCAAGGTGGAAGTCTTATATCATCCGAATGCCCCAAAGAAGTGTTAGATT
TAGTTCAAGAAAAAATAAAAGATCGATTAGAAACAGGATTAGATCTTTTAAAATTGGAATCGTGGATTCTTTCCTATAAA
GATGAACATCCAGAATGGAAGGAAAATTTTTCTTATAAAGAATTTTTAGAACTTGTAAGTCTTATATTAATGTACGAATA
CACAAGAGTTGATTACGAAAGTAATCTTTCAAAGTTAGAAGCCATCTTTCAATTTAAAACAGAACTTCACAAAAAGATAA
TTGGAATCGATTCAATTGCTCTTTCCAGATTATTTTTTAAACTTTCTATTTAG

Upstream 100 bases:

>100_bases
TGGCCCAATTACTCAAAAGATTCAAAACTTATTTTTTAATCTAGTGATTAACAAAGAAGAAAAATACAGACATTGGTTAA
CTCCAGTATATTAGAAAAGA

Downstream 100 bases:

>100_bases
AATATATTCAAAATTTTGAATATATGTTACTCTACGATTACTCCTTTAACGTTAGTCAAAATAAAAAAGGAATCTATTGA
ATAATTGTGACATAATTAAT

Product: DNA polymerase III subunit-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MKSFQLDEILGQEVALTFLKRYISKPETIPPLLIFHGPDGTGKESASERFIKNVLCFEGTSCGVCASCKSFIHNSHPDYI
RFPEESGKIIPIGSEDNPEEFSIRWLIRSRLNYRPHLSKFRFIVFPDASLIGNEAETALLKSLEEAPPFSRFIFIVNNLD
KLKETIVSRAICVPFQYLNQEDLRKINTNLGLSTFPFQGGSLISSECPKEVLDLVQEKIKDRLETGLDLLKLESWILSYK
DEHPEWKENFSYKEFLELVSLILMYEYTRVDYESNLSKLEAIFQFKTELHKKIIGIDSIALSRLFFKLSI

Sequences:

>Translated_310_residues
MKSFQLDEILGQEVALTFLKRYISKPETIPPLLIFHGPDGTGKESASERFIKNVLCFEGTSCGVCASCKSFIHNSHPDYI
RFPEESGKIIPIGSEDNPEEFSIRWLIRSRLNYRPHLSKFRFIVFPDASLIGNEAETALLKSLEEAPPFSRFIFIVNNLD
KLKETIVSRAICVPFQYLNQEDLRKINTNLGLSTFPFQGGSLISSECPKEVLDLVQEKIKDRLETGLDLLKLESWILSYK
DEHPEWKENFSYKEFLELVSLILMYEYTRVDYESNLSKLEAIFQFKTELHKKIIGIDSIALSRLFFKLSI
>Mature_310_residues
MKSFQLDEILGQEVALTFLKRYISKPETIPPLLIFHGPDGTGKESASERFIKNVLCFEGTSCGVCASCKSFIHNSHPDYI
RFPEESGKIIPIGSEDNPEEFSIRWLIRSRLNYRPHLSKFRFIVFPDASLIGNEAETALLKSLEEAPPFSRFIFIVNNLD
KLKETIVSRAICVPFQYLNQEDLRKINTNLGLSTFPFQGGSLISSECPKEVLDLVQEKIKDRLETGLDLLKLESWILSYK
DEHPEWKENFSYKEFLELVSLILMYEYTRVDYESNLSKLEAIFQFKTELHKKIIGIDSIALSRLFFKLSI

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786676, Length=180, Percent_Identity=27.2222222222222, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763
- InterPro:   IPR021029 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3; PF12170 DNA_pol3_tau_5 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 35736; Mature: 35736

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSFQLDEILGQEVALTFLKRYISKPETIPPLLIFHGPDGTGKESASERFIKNVLCFEGT
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCC
SCGVCASCKSFIHNSHPDYIRFPEESGKIIPIGSEDNPEEFSIRWLIRSRLNYRPHLSKF
CCCHHHHHHHHHHCCCCCCEECCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHE
RFIVFPDASLIGNEAETALLKSLEEAPPFSRFIFIVNNLDKLKETIVSRAICVPFQYLNQ
EEEEECCHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
EDLRKINTNLGLSTFPFQGGSLISSECPKEVLDLVQEKIKDRLETGLDLLKLESWILSYK
HHHHHHHHCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DEHPEWKENFSYKEFLELVSLILMYEYTRVDYESNLSKLEAIFQFKTELHKKIIGIDSIA
CCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
LSRLFFKLSI
HHHHHHHHCC
>Mature Secondary Structure
MKSFQLDEILGQEVALTFLKRYISKPETIPPLLIFHGPDGTGKESASERFIKNVLCFEGT
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCC
SCGVCASCKSFIHNSHPDYIRFPEESGKIIPIGSEDNPEEFSIRWLIRSRLNYRPHLSKF
CCCHHHHHHHHHHCCCCCCEECCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHE
RFIVFPDASLIGNEAETALLKSLEEAPPFSRFIFIVNNLDKLKETIVSRAICVPFQYLNQ
EEEEECCHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
EDLRKINTNLGLSTFPFQGGSLISSECPKEVLDLVQEKIKDRLETGLDLLKLESWILSYK
HHHHHHHHCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DEHPEWKENFSYKEFLELVSLILMYEYTRVDYESNLSKLEAIFQFKTELHKKIIGIDSIA
CCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
LSRLFFKLSI
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]