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The map label for this gene is 45659213

Identifier: 45659213

GI number: 45659213

Start: 4163062

End: 4164495

Strand: Direct

Name: 45659213

Synonym: LIC13396

Alternate gene names: NA

Gene position: 4163062-4164495 (Clockwise)

Preceding gene: 45659212

Following gene: 45659214

Centisome position: 97.33

GC content: 35.56

Gene sequence:

>1434_bases
ATGTCTTTATTACCTACCGTATGTATTATCGGTGCAGGTCCCAGTGGAATCGCTGTATGCAAAGCGCTTAAAGATAAAGG
AATTCCGTTTGAATGTTACGAAGCGGGAAGTGAGGTCGGTGGAAACTGGAAATTCAAGAACGATAATAAAATGAGTAGCA
TCTATAAGTCTTTGCATACCAACACTCATAAAGATAAAATGCAATACAAAGACTATCCTATGCCAAATTCTTACGCCGCT
TATCCCGATCATCAAAAAATCTCAGAATACTTCATAAACTACGTTAATCATTTCGGATTTCGAGATCATATTTTTTTTAA
AACTCCAGTAACTCACGTAAAACATGAAGAAGACGGAACATGGTCAATATTAACTCAAGATGGAAAACAAAAATATTATG
ATGTACTCATAGTATCCAATGGGCATCACTGGTCTCAAAGATGGCCCAAACCGGATTTTCCGGGAAAATTTACGGGAGAT
ATCATTCATTCTCATTCGTATATAGATCCAAATAAGCCAATCCAATTAACTGGAAAACGTGTTGTAATTCTCGGAATGGG
AAACAGCGCTATGGATATTGCAGTCGAGCTCTGCCGTCCAGGAATTTCATCCAAAGTTTTTTTAGCGGCAAGAAGGGGGG
CTTATATTATTCCCAACTACCTCTTTGGAAAACCCCTAGATAAAATCGCTACTCTCTTTCCTGTTCATACTCCATTTTGG
TTAAAAAGTCTTATTATAAAATTTGCATTAAAATTAGGAGTAGGAAATGTTGAAGATTTCGGTCTTCAAAAGCCAGATCA
TAAACCAGGAGCTGCTCACTTTACAATTTCGCAGGATATTCTCGTTCGATTAGGCAGAGGAGATATAATTCCAAAACCAA
ATATAGAGTCGTATAACGGTAATAAGGTGAAATTTGTAGATGGCAGTGAAGAAGAAATAGACGTAATCATTTATTGTACC
GGTTATGACGTAAAATTTCCGTTTTTTGACGAAAACTTCCTCTCAGCAAAAGACAACCATCTGCCTCTATTTCATAGGAT
GGTAAAACCAGAATTTAAAAATCTTTTTTTTGTAGGGTTATTTCAACCTCTTGGACCAATTGCTCCTTTATCCGAGTTTC
AAGGAAAATGGATTTCTGAATATCTAGTCGGAAATTATGAATTTCCATCTGAAGAAAAAATGAATCAATCAATTGAAAAA
TATGAATCCAAAATGAAAAGACGTTATATAACATCTGCAAGACATACGATGCAGGTGGATTTTGAAGTTTTTTTGTATGA
TATGAAATCCGAATTGAAAAAAGGCATCAAAAGAGCGGCTAAAAATGGAAATAAACTTCCAGTCCCCGCCCTTGCTCGAA
ACAAATCTATTTTGTCTAATGACATCCCTGTAAAACGATTTAAAAACAAAACTGAGTTATTCTCAGAAATTTAA

Upstream 100 bases:

>100_bases
GTCATATATTTTACTCGAAACTTTTTCATTGACTATATTATAATTTCAAAACATTTATCATATATCTTAACTACTTATCA
TTTATAGAATTAGGAGAGAA

Downstream 100 bases:

>100_bases
ATTCGTTTTCTATGGAAAATATTTTAAAGAAAACCCAAGGCGCTTTTAATATACGTCCTTAGATTTTTGCAAATTTTACG
ATCTAACGAGCAGAAGGAGA

Product: monooxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 476

Protein sequence:

>477_residues
MSLLPTVCIIGAGPSGIAVCKALKDKGIPFECYEAGSEVGGNWKFKNDNKMSSIYKSLHTNTHKDKMQYKDYPMPNSYAA
YPDHQKISEYFINYVNHFGFRDHIFFKTPVTHVKHEEDGTWSILTQDGKQKYYDVLIVSNGHHWSQRWPKPDFPGKFTGD
IIHSHSYIDPNKPIQLTGKRVVILGMGNSAMDIAVELCRPGISSKVFLAARRGAYIIPNYLFGKPLDKIATLFPVHTPFW
LKSLIIKFALKLGVGNVEDFGLQKPDHKPGAAHFTISQDILVRLGRGDIIPKPNIESYNGNKVKFVDGSEEEIDVIIYCT
GYDVKFPFFDENFLSAKDNHLPLFHRMVKPEFKNLFFVGLFQPLGPIAPLSEFQGKWISEYLVGNYEFPSEEKMNQSIEK
YESKMKRRYITSARHTMQVDFEVFLYDMKSELKKGIKRAAKNGNKLPVPALARNKSILSNDIPVKRFKNKTELFSEI

Sequences:

>Translated_477_residues
MSLLPTVCIIGAGPSGIAVCKALKDKGIPFECYEAGSEVGGNWKFKNDNKMSSIYKSLHTNTHKDKMQYKDYPMPNSYAA
YPDHQKISEYFINYVNHFGFRDHIFFKTPVTHVKHEEDGTWSILTQDGKQKYYDVLIVSNGHHWSQRWPKPDFPGKFTGD
IIHSHSYIDPNKPIQLTGKRVVILGMGNSAMDIAVELCRPGISSKVFLAARRGAYIIPNYLFGKPLDKIATLFPVHTPFW
LKSLIIKFALKLGVGNVEDFGLQKPDHKPGAAHFTISQDILVRLGRGDIIPKPNIESYNGNKVKFVDGSEEEIDVIIYCT
GYDVKFPFFDENFLSAKDNHLPLFHRMVKPEFKNLFFVGLFQPLGPIAPLSEFQGKWISEYLVGNYEFPSEEKMNQSIEK
YESKMKRRYITSARHTMQVDFEVFLYDMKSELKKGIKRAAKNGNKLPVPALARNKSILSNDIPVKRFKNKTELFSEI
>Mature_476_residues
SLLPTVCIIGAGPSGIAVCKALKDKGIPFECYEAGSEVGGNWKFKNDNKMSSIYKSLHTNTHKDKMQYKDYPMPNSYAAY
PDHQKISEYFINYVNHFGFRDHIFFKTPVTHVKHEEDGTWSILTQDGKQKYYDVLIVSNGHHWSQRWPKPDFPGKFTGDI
IHSHSYIDPNKPIQLTGKRVVILGMGNSAMDIAVELCRPGISSKVFLAARRGAYIIPNYLFGKPLDKIATLFPVHTPFWL
KSLIIKFALKLGVGNVEDFGLQKPDHKPGAAHFTISQDILVRLGRGDIIPKPNIESYNGNKVKFVDGSEEEIDVIIYCTG
YDVKFPFFDENFLSAKDNHLPLFHRMVKPEFKNLFFVGLFQPLGPIAPLSEFQGKWISEYLVGNYEFPSEEKMNQSIEKY
ESKMKRRYITSARHTMQVDFEVFLYDMKSELKKGIKRAAKNGNKLPVPALARNKSILSNDIPVKRFKNKTELFSEI

Specific function: Unknown

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Homo sapiens, GI221316672, Length=435, Percent_Identity=34.7126436781609, Blast_Score=229, Evalue=4e-60,
Organism=Homo sapiens, GI4503757, Length=450, Percent_Identity=31.7777777777778, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI221316674, Length=420, Percent_Identity=34.0476190476191, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI4503759, Length=427, Percent_Identity=31.1475409836066, Blast_Score=192, Evalue=8e-49,
Organism=Homo sapiens, GI4503755, Length=441, Percent_Identity=29.2517006802721, Blast_Score=189, Evalue=6e-48,
Organism=Homo sapiens, GI50541965, Length=451, Percent_Identity=30.3769401330377, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI50541961, Length=451, Percent_Identity=30.3769401330377, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI221316678, Length=233, Percent_Identity=36.9098712446352, Blast_Score=133, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI25145785, Length=429, Percent_Identity=31.4685314685315, Blast_Score=244, Evalue=7e-65,
Organism=Caenorhabditis elegans, GI25150462, Length=452, Percent_Identity=33.1858407079646, Blast_Score=229, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI17561948, Length=444, Percent_Identity=31.981981981982, Blast_Score=210, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17541300, Length=438, Percent_Identity=30.5936073059361, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17555726, Length=446, Percent_Identity=31.8385650224215, Blast_Score=204, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI193202226, Length=396, Percent_Identity=28.030303030303, Blast_Score=131, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17506045, Length=213, Percent_Identity=30.0469483568075, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI19921694, Length=409, Percent_Identity=26.8948655256724, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI19922866, Length=210, Percent_Identity=27.6190476190476, Blast_Score=97, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: NA

Molecular weight: Translated: 54451; Mature: 54320

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLPTVCIIGAGPSGIAVCKALKDKGIPFECYEAGSEVGGNWKFKNDNKMSSIYKSLHT
CCCCCCEEEEECCCCHHHHHHHHHHCCCCCHHHHCCCCCCCCEEECCCCHHHHHHHHHHC
NTHKDKMQYKDYPMPNSYAAYPDHQKISEYFINYVNHFGFRDHIFFKTPVTHVKHEEDGT
CCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCCC
WSILTQDGKQKYYDVLIVSNGHHWSQRWPKPDFPGKFTGDIIHSHSYIDPNKPIQLTGKR
EEEEECCCCCEEEEEEEEECCCCHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCEEECCCE
VVILGMGNSAMDIAVELCRPGISSKVFLAARRGAYIIPNYLFGKPLDKIATLFPVHTPFW
EEEEECCCCHHHHHHHHHCCCCCCEEEEEECCCCEEECCHHHCCCHHHHHHHHCCCCHHH
LKSLIIKFALKLGVGNVEDFGLQKPDHKPGAAHFTISQDILVRLGRGDIIPKPNIESYNG
HHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCEEEEECHHHHHEECCCCCCCCCCCCCCCC
NKVKFVDGSEEEIDVIIYCTGYDVKFPFFDENFLSAKDNHLPLFHRMVKPEFKNLFFVGL
CEEEEECCCCCCEEEEEEEECCCEECCCCCCCHHCCCCCCCHHHHHHHCHHHHCEEEEEE
FQPLGPIAPLSEFQGKWISEYLVGNYEFPSEEKMNQSIEKYESKMKRRYITSARHTMQVD
CCCCCCCCCHHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
FEVFLYDMKSELKKGIKRAAKNGNKLPVPALARNKSILSNDIPVKRFKNKTELFSEI
HHHEEHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHCCCCCHHHHCCHHHHHHCC
>Mature Secondary Structure 
SLLPTVCIIGAGPSGIAVCKALKDKGIPFECYEAGSEVGGNWKFKNDNKMSSIYKSLHT
CCCCCEEEEECCCCHHHHHHHHHHCCCCCHHHHCCCCCCCCEEECCCCHHHHHHHHHHC
NTHKDKMQYKDYPMPNSYAAYPDHQKISEYFINYVNHFGFRDHIFFKTPVTHVKHEEDGT
CCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCCC
WSILTQDGKQKYYDVLIVSNGHHWSQRWPKPDFPGKFTGDIIHSHSYIDPNKPIQLTGKR
EEEEECCCCCEEEEEEEEECCCCHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCEEECCCE
VVILGMGNSAMDIAVELCRPGISSKVFLAARRGAYIIPNYLFGKPLDKIATLFPVHTPFW
EEEEECCCCHHHHHHHHHCCCCCCEEEEEECCCCEEECCHHHCCCHHHHHHHHCCCCHHH
LKSLIIKFALKLGVGNVEDFGLQKPDHKPGAAHFTISQDILVRLGRGDIIPKPNIESYNG
HHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCEEEEECHHHHHEECCCCCCCCCCCCCCCC
NKVKFVDGSEEEIDVIIYCTGYDVKFPFFDENFLSAKDNHLPLFHRMVKPEFKNLFFVGL
CEEEEECCCCCCEEEEEEEECCCEECCCCCCCHHCCCCCCCHHHHHHHCHHHHCEEEEEE
FQPLGPIAPLSEFQGKWISEYLVGNYEFPSEEKMNQSIEKYESKMKRRYITSARHTMQVD
CCCCCCCCCHHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
FEVFLYDMKSELKKGIKRAAKNGNKLPVPALARNKSILSNDIPVKRFKNKTELFSEI
HHHEEHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHCCCCCHHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]