| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
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The map label for this gene is rsbU [H]
Identifier: 45659094
GI number: 45659094
Start: 4012567
End: 4014945
Strand: Direct
Name: rsbU [H]
Synonym: LIC13273
Alternate gene names: 45659094
Gene position: 4012567-4014945 (Clockwise)
Preceding gene: 45659093
Following gene: 45659098
Centisome position: 93.81
GC content: 33.25
Gene sequence:
>2379_bases TTGAGAAATATACTTTTACTTTTTATATCTCTGATCCTACTCAGTATCGTTTTATTGATAGGAGTTTTACAAACTTCTTC TGAAACTTTAAAACCTCCTTTTTATTACTACCCAAATGGAACAATTATTCAAAGTAGCGAAGAGTTTCCAGGTATTTTAG GGAAAAAGGTAGACCTTTTAGAATTAGAAATCGCGATCAAGATGGCCGAGTCTGGACAATCTTATGAAAATGGAATACAC GTTTACGATAAAGGAGTAAGCGAAACGATTCCTGTAATTTTAGCACCTAAATCATATTATTCAGTCGTTAAGGAATTCAC AAGGGACATTCTTATATCGTTGCTTTATTTATCTGTCGCGATTTGGTTTTTCTTTTATACAAGAGATCTCTACATGCTTT TATTGTTCGGATCCTTGTCTTGTTTAAGTTTATTTAATTTCTTCTTAGTTGGATTTCACGAGTTTCATTTTTTATTTTTC TTTTTTCTATATTTTACCGCATTCGTAATTTTGAATATATCTTTCAGACTTAGAGGAAAGGAACTTCCCACTCGTTGGTT TGCGCCAGAAATTATTTTTTCTTTGATCGCCGGTTTTGTGGGTAGAACACAAAAAGCAGATCCTCATATCTTTGGAATAC TTGCCACAAATGGAGTTTACTTTATACTATTCAGCTCCGTAATCTGTATTTTCTTTCTTGTAACAGACTCGATACGAAAT CTTTTTCCAATTCAGAGTTTATTCAAGAAATTAAGTCTGATCTTAGCATTCAGTGCAATTTCCATTCTACCTTTTGTTTC TGTAGAATTTTCGGAGTTTATCTCTCCCGATTTTTCTAAACTTATGATTTTATTTGCATTTCTAATCTTTCCCGCATTGA TCATATACGGAACCTTTACTTATTCTATTGTTCCTGTGCAGATCGCATTCAGTTCTTCTCTCACTTCCATTTATCTAATT CTTATATTAGCAGGAGGTTATCTATTTTTGTTAGGAGCGTTTTTCAAATTCGATCCAATCGCAACGGATAAGTATTTGGA AGAATTTAATGTTTTATTTCTTTGTTCCAGCATTTACACAATGAGTTCCATCAACAGACGTCTTTCTAATCTTGTAGATA CTTGGAGTTTTAAACGAAATCAAAAGTTACACTCCGCTATGGAAACAATTTCTGCTATGATCAGCGCTCCAATTTCTATG AGAGCTACCATCAACAACATGATGAGAAAAGTTTCAGAAGCCCTGGATATTTCTAAAATTTTAGTCTTAATACCTGCGGA TAAATTTCCAAGAACCGATCTGAAAAACATCAACTTCATTCGAATCTCTTCCAACTCCGAAATATGGCAGTATTTTGCGA CAAATACGGAAGTTACGGTCACTACACATCTTGCCTATGGACTTGGAATTCGAGAATCAGTTTACAAATTTCTACATAAC TCAGGAGTACAACTTACATATCCGATTTTCAATTATTCCAGAGGAAAAGAGGTTTTGGCTGTGTTTCTTGTGGGAGAAAA GAAAAACAGAAAAAACTTTAACTTAGGAGAACTTCATTTTTTAAAAGAATGTACTCGAATGGCTTCGATGCTTTTACAGA ACTATACTTTATTAGCAGAGGAAGTGGAGAAAAAAAGAATTGTTCGTGATCTTAATATGGCTTCGATCATCGATAAAACG CTTCACGTAGCGGAAAGTAGGCACATTCAAGGAGTTAAAATAGGATTTTTTTCTATACCAGCTGTAGGGATCTCAGGTGA TTATTTAGATATTCAAAAATTAGATTCAAACACGATGTTGCTGGCTTTAGGAGATGTTTCAGGCCATGGATTAGGAACTG GTTATCTAGTGAGCGCGATCAGAGGTATCATACAAAATCAAATTCGAAAAAAATCGGATTTATCTAAGATATTCAAAGTA ATTAATTCGTTTCTCATTGAAAGATATAGAGGAAGTGAGTTTATGACTTTCATTTGTGGAGAATATAATTCCCAAAAAGA AACATTTCATTACATCAACGCAGGTCATTCTTCTCCAATTTGTATTCGAAAAGATGGAAAAATAGAATTAAGATCGGAAA CTCAAAGAGTTTTAGGCGTCTTACATACAGAATATAAACACTTAACGATTCCGATTTACTCTGGTGATAAATTAATCTTA TTCACAGATGGAGTTACAGAAACGTTTAACGATAACGAAGAAATTTTTGGAGATGAAAACTTTTTAAATCTTTTAAAGAA TAATCATCACTTAGATCCACAAGATCTATCTGATCTTGTACTAAAAACGATTCAAGAGTTTCGTGGTAAGAAAGATCCTA GTGATGATATATCTTTCATCTGCATCGAAGTGAATAAAAATTACGATTCCAATCAGTAA
Upstream 100 bases:
>100_bases CAGCTGGCTGGGAAGTAGAAGAGAATATAGAAAAAGACCCATTGGTCCTTACTTGGAAGAATCGCACGATGATTTCGATT CATGACCTGAGGTTTCCATC
Downstream 100 bases:
>100_bases AATAAATAAATTAAAAAAAAATGTAAAAAAATATTAAAACACTTTACATTTTTATCTTGATCCATTAATTATGTCTCTAA TCACGGCGTTAAGCTTTAAG
Product: sigma factor regulatory protein
Products: NA
Alternate protein names: Sigma factor sigB regulation protein rsbU [H]
Number of amino acids: Translated: 792; Mature: 792
Protein sequence:
>792_residues MRNILLLFISLILLSIVLLIGVLQTSSETLKPPFYYYPNGTIIQSSEEFPGILGKKVDLLELEIAIKMAESGQSYENGIH VYDKGVSETIPVILAPKSYYSVVKEFTRDILISLLYLSVAIWFFFYTRDLYMLLLFGSLSCLSLFNFFLVGFHEFHFLFF FFLYFTAFVILNISFRLRGKELPTRWFAPEIIFSLIAGFVGRTQKADPHIFGILATNGVYFILFSSVICIFFLVTDSIRN LFPIQSLFKKLSLILAFSAISILPFVSVEFSEFISPDFSKLMILFAFLIFPALIIYGTFTYSIVPVQIAFSSSLTSIYLI LILAGGYLFLLGAFFKFDPIATDKYLEEFNVLFLCSSIYTMSSINRRLSNLVDTWSFKRNQKLHSAMETISAMISAPISM RATINNMMRKVSEALDISKILVLIPADKFPRTDLKNINFIRISSNSEIWQYFATNTEVTVTTHLAYGLGIRESVYKFLHN SGVQLTYPIFNYSRGKEVLAVFLVGEKKNRKNFNLGELHFLKECTRMASMLLQNYTLLAEEVEKKRIVRDLNMASIIDKT LHVAESRHIQGVKIGFFSIPAVGISGDYLDIQKLDSNTMLLALGDVSGHGLGTGYLVSAIRGIIQNQIRKKSDLSKIFKV INSFLIERYRGSEFMTFICGEYNSQKETFHYINAGHSSPICIRKDGKIELRSETQRVLGVLHTEYKHLTIPIYSGDKLIL FTDGVTETFNDNEEIFGDENFLNLLKNNHHLDPQDLSDLVLKTIQEFRGKKDPSDDISFICIEVNKNYDSNQ
Sequences:
>Translated_792_residues MRNILLLFISLILLSIVLLIGVLQTSSETLKPPFYYYPNGTIIQSSEEFPGILGKKVDLLELEIAIKMAESGQSYENGIH VYDKGVSETIPVILAPKSYYSVVKEFTRDILISLLYLSVAIWFFFYTRDLYMLLLFGSLSCLSLFNFFLVGFHEFHFLFF FFLYFTAFVILNISFRLRGKELPTRWFAPEIIFSLIAGFVGRTQKADPHIFGILATNGVYFILFSSVICIFFLVTDSIRN LFPIQSLFKKLSLILAFSAISILPFVSVEFSEFISPDFSKLMILFAFLIFPALIIYGTFTYSIVPVQIAFSSSLTSIYLI LILAGGYLFLLGAFFKFDPIATDKYLEEFNVLFLCSSIYTMSSINRRLSNLVDTWSFKRNQKLHSAMETISAMISAPISM RATINNMMRKVSEALDISKILVLIPADKFPRTDLKNINFIRISSNSEIWQYFATNTEVTVTTHLAYGLGIRESVYKFLHN SGVQLTYPIFNYSRGKEVLAVFLVGEKKNRKNFNLGELHFLKECTRMASMLLQNYTLLAEEVEKKRIVRDLNMASIIDKT LHVAESRHIQGVKIGFFSIPAVGISGDYLDIQKLDSNTMLLALGDVSGHGLGTGYLVSAIRGIIQNQIRKKSDLSKIFKV INSFLIERYRGSEFMTFICGEYNSQKETFHYINAGHSSPICIRKDGKIELRSETQRVLGVLHTEYKHLTIPIYSGDKLIL FTDGVTETFNDNEEIFGDENFLNLLKNNHHLDPQDLSDLVLKTIQEFRGKKDPSDDISFICIEVNKNYDSNQ >Mature_792_residues MRNILLLFISLILLSIVLLIGVLQTSSETLKPPFYYYPNGTIIQSSEEFPGILGKKVDLLELEIAIKMAESGQSYENGIH VYDKGVSETIPVILAPKSYYSVVKEFTRDILISLLYLSVAIWFFFYTRDLYMLLLFGSLSCLSLFNFFLVGFHEFHFLFF FFLYFTAFVILNISFRLRGKELPTRWFAPEIIFSLIAGFVGRTQKADPHIFGILATNGVYFILFSSVICIFFLVTDSIRN LFPIQSLFKKLSLILAFSAISILPFVSVEFSEFISPDFSKLMILFAFLIFPALIIYGTFTYSIVPVQIAFSSSLTSIYLI LILAGGYLFLLGAFFKFDPIATDKYLEEFNVLFLCSSIYTMSSINRRLSNLVDTWSFKRNQKLHSAMETISAMISAPISM RATINNMMRKVSEALDISKILVLIPADKFPRTDLKNINFIRISSNSEIWQYFATNTEVTVTTHLAYGLGIRESVYKFLHN SGVQLTYPIFNYSRGKEVLAVFLVGEKKNRKNFNLGELHFLKECTRMASMLLQNYTLLAEEVEKKRIVRDLNMASIIDKT LHVAESRHIQGVKIGFFSIPAVGISGDYLDIQKLDSNTMLLALGDVSGHGLGTGYLVSAIRGIIQNQIRKKSDLSKIFKV INSFLIERYRGSEFMTFICGEYNSQKETFHYINAGHSSPICIRKDGKIELRSETQRVLGVLHTEYKHLTIPIYSGDKLIL FTDGVTETFNDNEEIFGDENFLNLLKNNHHLDPQDLSDLVLKTIQEFRGKKDPSDDISFICIEVNKNYDSNQ
Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]
COG id: COG2208
COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PP2C-like domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR017944 - InterPro: IPR001932 - InterPro: IPR014787 - InterPro: IPR010822 - ProDom: PD685490 [H]
Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]
EC number: =3.1.3.3 [H]
Molecular weight: Translated: 90291; Mature: 90291
Theoretical pI: Translated: 7.87; Mature: 7.87
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRNILLLFISLILLSIVLLIGVLQTSSETLKPPFYYYPNGTIIQSSEEFPGILGKKVDLL CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCEEECCCCCCCCCCCCCHHE ELEIAIKMAESGQSYENGIHVYDKGVSETIPVILAPKSYYSVVKEFTRDILISLLYLSVA EEEEEEEEHHCCCCHHCCEEEEECCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHH IWFFFYTRDLYMLLLFGSLSCLSLFNFFLVGFHEFHFLFFFFLYFTAFVILNISFRLRGK HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC ELPTRWFAPEIIFSLIAGFVGRTQKADPHIFGILATNGVYFILFSSVICIFFLVTDSIRN CCCCHHCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH LFPIQSLFKKLSLILAFSAISILPFVSVEFSEFISPDFSKLMILFAFLIFPALIIYGTFT HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH YSIVPVQIAFSSSLTSIYLILILAGGYLFLLGAFFKFDPIATDKYLEEFNVLFLCSSIYT EEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH MSSINRRLSNLVDTWSFKRNQKLHSAMETISAMISAPISMRATINNMMRKVSEALDISKI HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEE LVLIPADKFPRTDLKNINFIRISSNSEIWQYFATNTEVTVTTHLAYGLGIRESVYKFLHN EEEEECCCCCCCCCCCCEEEEECCCCCEEHHEECCCEEEEEEEHHHCCCHHHHHHHHHHC SGVQLTYPIFNYSRGKEVLAVFLVGEKKNRKNFNLGELHFLKECTRMASMLLQNYTLLAE CCCEEEEECCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH EVEKKRIVRDLNMASIIDKTLHVAESRHIQGVKIGFFSIPAVGISGDYLDIQKLDSNTML HHHHHHHHHHCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCEEEEEECCCCEEE LALGDVSGHGLGTGYLVSAIRGIIQNQIRKKSDLSKIFKVINSFLIERYRGSEFMTFICG EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC EYNSQKETFHYINAGHSSPICIRKDGKIELRSETQRVLGVLHTEYKHLTIPIYSGDKLIL CCCCCCHHEEEEECCCCCCEEEECCCCEEEHHHHHHHHHHHHCCCEEEEEEEECCCEEEE FTDGVTETFNDNEEIFGDENFLNLLKNNHHLDPQDLSDLVLKTIQEFRGKKDPSDDISFI EECCCCCCCCCCCHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEE CIEVNKNYDSNQ EEEEECCCCCCC >Mature Secondary Structure MRNILLLFISLILLSIVLLIGVLQTSSETLKPPFYYYPNGTIIQSSEEFPGILGKKVDLL CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCEEECCCCCCCCCCCCCHHE ELEIAIKMAESGQSYENGIHVYDKGVSETIPVILAPKSYYSVVKEFTRDILISLLYLSVA EEEEEEEEHHCCCCHHCCEEEEECCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHH IWFFFYTRDLYMLLLFGSLSCLSLFNFFLVGFHEFHFLFFFFLYFTAFVILNISFRLRGK HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC ELPTRWFAPEIIFSLIAGFVGRTQKADPHIFGILATNGVYFILFSSVICIFFLVTDSIRN CCCCHHCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH LFPIQSLFKKLSLILAFSAISILPFVSVEFSEFISPDFSKLMILFAFLIFPALIIYGTFT HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH YSIVPVQIAFSSSLTSIYLILILAGGYLFLLGAFFKFDPIATDKYLEEFNVLFLCSSIYT EEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH MSSINRRLSNLVDTWSFKRNQKLHSAMETISAMISAPISMRATINNMMRKVSEALDISKI HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEE LVLIPADKFPRTDLKNINFIRISSNSEIWQYFATNTEVTVTTHLAYGLGIRESVYKFLHN EEEEECCCCCCCCCCCCEEEEECCCCCEEHHEECCCEEEEEEEHHHCCCHHHHHHHHHHC SGVQLTYPIFNYSRGKEVLAVFLVGEKKNRKNFNLGELHFLKECTRMASMLLQNYTLLAE CCCEEEEECCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH EVEKKRIVRDLNMASIIDKTLHVAESRHIQGVKIGFFSIPAVGISGDYLDIQKLDSNTML HHHHHHHHHHCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCEEEEEECCCCEEE LALGDVSGHGLGTGYLVSAIRGIIQNQIRKKSDLSKIFKVINSFLIERYRGSEFMTFICG EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC EYNSQKETFHYINAGHSSPICIRKDGKIELRSETQRVLGVLHTEYKHLTIPIYSGDKLIL CCCCCCHHEEEEECCCCCCEEEECCCCEEEHHHHHHHHHHHHCCCEEEEEEEECCCEEEE FTDGVTETFNDNEEIFGDENFLNLLKNNHHLDPQDLSDLVLKTIQEFRGKKDPSDDISFI EECCCCCCCCCCCHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEE CIEVNKNYDSNQ EEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]