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The map label for this gene is algU [H]

Identifier: 45659087

GI number: 45659087

Start: 4005292

End: 4005870

Strand: Direct

Name: algU [H]

Synonym: LIC13266

Alternate gene names: 45659087

Gene position: 4005292-4005870 (Clockwise)

Preceding gene: 45659086

Following gene: 45659088

Centisome position: 93.64

GC content: 35.23

Gene sequence:

>579_bases
ATGAGGGAACCAATCCTATGCAACCGGGAAGACTGGGACTGCATTCAGAAAGTTTTGCACGGCGATTTCAATTCTTTTGA
ACTGTTGATGAATCGTTATCAAGGTTTGGTTTATTCCCAAGCGATCAAAGCGTTTCGAAACGAGACCGAAGCTGAAGACT
TTACACAGGACATTTTCTTAAAAGCTTTTGAAAGTTTATCTACGTTTCAAGGTAAATCACAATTCTCCACTTGGTTATTT
GTAATCGCTCGTAACGAGATTATTCGAAAATACCGCAAAGAATACCCGGAAATCTCCGGATTAGACGCGCTTCTTTTAGC
AGAAAACGAAAAAGAAGGTGAGATCTATTCCGAGCAGGAATCAAAATTTCTAAAACAGGAAAACTCAGAGAAAATTAGAA
ATCTAGTAGCAAGGCTGCCAGAGCTTTATAGAAAACCGATCACACTTCACTATTTCGAAAACATGTCTTATAAAGAAATT
TCTAAAAAATTAAACTTGAAAATGAACACTTTAAAGAGTTATATTTTCAGAGGTAAAGAAATCATGAAAGATTGGTTAAA
TAATGAAAAAAAAGAATGA

Upstream 100 bases:

>100_bases
TCATTTCTGTTTTAGGACAATCGCTTGCAATGCTCGGCGGACTTGTCCCACTAGGAACCGGTCTGGGATTACTCTGTTAT
TATAAATTTTCCCAGTCCTG

Downstream 100 bases:

>100_bases
TTTCGTTCCGGCGGAACTCGAGGAAAAACTTCACTTTTTCGAAGACGAAACTCTAAATTCTCAAACAAATACGCCTGTTC
CACCGGACTTAAAACGCAGA

Product: RNA polymerase ECF-type sigma factor

Products: NA

Alternate protein names: Sigma-30 [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MREPILCNREDWDCIQKVLHGDFNSFELLMNRYQGLVYSQAIKAFRNETEAEDFTQDIFLKAFESLSTFQGKSQFSTWLF
VIARNEIIRKYRKEYPEISGLDALLLAENEKEGEIYSEQESKFLKQENSEKIRNLVARLPELYRKPITLHYFENMSYKEI
SKKLNLKMNTLKSYIFRGKEIMKDWLNNEKKE

Sequences:

>Translated_192_residues
MREPILCNREDWDCIQKVLHGDFNSFELLMNRYQGLVYSQAIKAFRNETEAEDFTQDIFLKAFESLSTFQGKSQFSTWLF
VIARNEIIRKYRKEYPEISGLDALLLAENEKEGEIYSEQESKFLKQENSEKIRNLVARLPELYRKPITLHYFENMSYKEI
SKKLNLKMNTLKSYIFRGKEIMKDWLNNEKKE
>Mature_192_residues
MREPILCNREDWDCIQKVLHGDFNSFELLMNRYQGLVYSQAIKAFRNETEAEDFTQDIFLKAFESLSTFQGKSQFSTWLF
VIARNEIIRKYRKEYPEISGLDALLLAENEKEGEIYSEQESKFLKQENSEKIRNLVARLPELYRKPITLHYFENMSYKEI
SKKLNLKMNTLKSYIFRGKEIMKDWLNNEKKE

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor regulates genes such as algD, involved in alginate biosynthesis [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=180, Percent_Identity=31.1111111111111, Blast_Score=87, Evalue=6e-19,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR014286
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 23038; Mature: 23038

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREPILCNREDWDCIQKVLHGDFNSFELLMNRYQGLVYSQAIKAFRNETEAEDFTQDIFL
CCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
KAFESLSTFQGKSQFSTWLFVIARNEIIRKYRKEYPEISGLDALLLAENEKEGEIYSEQE
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEECCCCCCCHHHHHH
SKFLKQENSEKIRNLVARLPELYRKPITLHYFENMSYKEISKKLNLKMNTLKSYIFRGKE
HHHHHHCCHHHHHHHHHHHHHHHHCCCEEEHHHCCCHHHHHHHHCCHHHHHHHHHHCCHH
IMKDWLNNEKKE
HHHHHHCCCCCC
>Mature Secondary Structure
MREPILCNREDWDCIQKVLHGDFNSFELLMNRYQGLVYSQAIKAFRNETEAEDFTQDIFL
CCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
KAFESLSTFQGKSQFSTWLFVIARNEIIRKYRKEYPEISGLDALLLAENEKEGEIYSEQE
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEECCCCCCCHHHHHH
SKFLKQENSEKIRNLVARLPELYRKPITLHYFENMSYKEISKKLNLKMNTLKSYIFRGKE
HHHHHHCCHHHHHHHHHHHHHHHHCCCEEEHHHCCCHHHHHHHHCCHHHHHHHHHHCCHH
IMKDWLNNEKKE
HHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8432708; 8378309; 7961421; 10984043; 7737518 [H]