Click here to switch to the map view.

The map label for this gene is murA

Identifier: 45659072

GI number: 45659072

Start: 3989142

End: 3990440

Strand: Direct

Name: murA

Synonym: LIC13251

Alternate gene names: 45659072

Gene position: 3989142-3990440 (Clockwise)

Preceding gene: 45659068

Following gene: 45659073

Centisome position: 93.27

GC content: 43.03

Gene sequence:

>1299_bases
ATGAGATCTTCGTATTTTAAGATCATTGGAAAGACCCCTCTTCATGGAACCGTGGTTCCACAAGGAAATAAAAACGAGGC
ATTACCATTGTTAGGAGCGGTCTGTATGGTTCCGGGAACCGTTCGTATTAGCAACATTCCTGTAATCTCAGACGTACTCA
TGCTTATGGAAGTTCTTCGTCATCTCGGTATGGAAATCACCGAAGAAGAACCTGGAACTTATATTTTTAAACACGATGGA
AATCTAAAAAATCAACTTCCCGAAGAACTCTGTTCTCGCATTCGAGGTGCGGTCACCTTAGCAGGTCCAATTCTTGCGAT
GACTGGAAGGGTTTTTTTACCAAAACCAGGCGGAGACAAAATAGGAAGAAGAAGACTAGACACTCATCTTCTCGCATTAC
AAGCATTAGGTGCAAGTATAGAAGTATTCCCGGACGGCTATGAGATTAAAGCGGATCAACTAAAAGGAACGGACATACTT
ATGGACGAGGCTTCCGTTACCGGAACCGAAAACGCGGTAATGGCCGCGGTTTTTGCAGAAGGTACTACAATCCTTCGTCA
CGCCGCAAGCGAACCTCACGTTCAAAGACTTTGTCATTTTTTAAATTCTGCAGGAGCCAAAATTTCAGGAATCGGTTCTA
ACATTCTTACGATCGAAGGTGTAACTTCTTTAAAACCTCCCGCCAAAGAGCACAAAATAGGATCTGATTATTTAGAAGTG
GGTTCGTTTATCAGTTTGGCCGCAGTCACAGGCGGAGAACTTATGATTCGAGACGTAGAATTGGAAGACATCCGTATGAT
CCGAATGGTTTATTCTCGTCTTGGAATCGAAGTGCGTCCACATGAAAACGGAATTTTAGTTCCTTCCGATCAGAAGATGG
AAATTATTCCGGATTATCATGGTGCAACTCCTAAAATAGACGATTCTCCTTGGCCTGGTTTTCCTGCGGATATGACTTCT
GTCGCGCTCGTTACCGCCACTCAGTGCAAAGGAACAGTTTTGATTCACGAAAAAATGTTCGAATCCAGGCTCTTCTTTGT
AGATAATATCATCGCAATGGGAGCACAGATTATTCTTTGTGATCCACATCGTGCAATCGTAATTGGTCATTCTAGACTTT
ACGGTCAAAAAGTAGCCAGCCCAGACATACGTGCTGGTATGGCAATGATCATTGCTGCTCTTTGTGCAGAAGGCACAAGT
TACATTCATAATATAGGTCAAATCGACAGAGGTTTTGAAAACATAGATACCCGCTTACGCGCGTTAGGTGCAAGAATCGA
AAGAGTAAACGCAGATTGA

Upstream 100 bases:

>100_bases
CAGTAAGAAGCCATTTTAAAAACCAAACTCAACGAATCAAAATTAACATCCTGCTAACATTTCGATTTGCCAGAAAGAAC
CTATCCTACAGTTTATCATT

Downstream 100 bases:

>100_bases
ACCGAAAAGATTTTTTTAAAAAAGGTCTTGCGAGAATGTTAGACTTCGCGCAGGAAAACGCGACCGAACTCGTTTCCGGT
TTTCAGGAAATCGTTTCTAA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MRSSYFKIIGKTPLHGTVVPQGNKNEALPLLGAVCMVPGTVRISNIPVISDVLMLMEVLRHLGMEITEEEPGTYIFKHDG
NLKNQLPEELCSRIRGAVTLAGPILAMTGRVFLPKPGGDKIGRRRLDTHLLALQALGASIEVFPDGYEIKADQLKGTDIL
MDEASVTGTENAVMAAVFAEGTTILRHAASEPHVQRLCHFLNSAGAKISGIGSNILTIEGVTSLKPPAKEHKIGSDYLEV
GSFISLAAVTGGELMIRDVELEDIRMIRMVYSRLGIEVRPHENGILVPSDQKMEIIPDYHGATPKIDDSPWPGFPADMTS
VALVTATQCKGTVLIHEKMFESRLFFVDNIIAMGAQIILCDPHRAIVIGHSRLYGQKVASPDIRAGMAMIIAALCAEGTS
YIHNIGQIDRGFENIDTRLRALGARIERVNAD

Sequences:

>Translated_432_residues
MRSSYFKIIGKTPLHGTVVPQGNKNEALPLLGAVCMVPGTVRISNIPVISDVLMLMEVLRHLGMEITEEEPGTYIFKHDG
NLKNQLPEELCSRIRGAVTLAGPILAMTGRVFLPKPGGDKIGRRRLDTHLLALQALGASIEVFPDGYEIKADQLKGTDIL
MDEASVTGTENAVMAAVFAEGTTILRHAASEPHVQRLCHFLNSAGAKISGIGSNILTIEGVTSLKPPAKEHKIGSDYLEV
GSFISLAAVTGGELMIRDVELEDIRMIRMVYSRLGIEVRPHENGILVPSDQKMEIIPDYHGATPKIDDSPWPGFPADMTS
VALVTATQCKGTVLIHEKMFESRLFFVDNIIAMGAQIILCDPHRAIVIGHSRLYGQKVASPDIRAGMAMIIAALCAEGTS
YIHNIGQIDRGFENIDTRLRALGARIERVNAD
>Mature_432_residues
MRSSYFKIIGKTPLHGTVVPQGNKNEALPLLGAVCMVPGTVRISNIPVISDVLMLMEVLRHLGMEITEEEPGTYIFKHDG
NLKNQLPEELCSRIRGAVTLAGPILAMTGRVFLPKPGGDKIGRRRLDTHLLALQALGASIEVFPDGYEIKADQLKGTDIL
MDEASVTGTENAVMAAVFAEGTTILRHAASEPHVQRLCHFLNSAGAKISGIGSNILTIEGVTSLKPPAKEHKIGSDYLEV
GSFISLAAVTGGELMIRDVELEDIRMIRMVYSRLGIEVRPHENGILVPSDQKMEIIPDYHGATPKIDDSPWPGFPADMTS
VALVTATQCKGTVLIHEKMFESRLFFVDNIIAMGAQIILCDPHRAIVIGHSRLYGQKVASPDIRAGMAMIIAALCAEGTS
YIHNIGQIDRGFENIDTRLRALGARIERVNAD

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=433, Percent_Identity=34.6420323325635, Blast_Score=224, Evalue=8e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 46910; Mature: 46910

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSSYFKIIGKTPLHGTVVPQGNKNEALPLLGAVCMVPGTVRISNIPVISDVLMLMEVLR
CCCCEEEEEECCCCCCEECCCCCCCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHH
HLGMEITEEEPGTYIFKHDGNLKNQLPEELCSRIRGAVTLAGPILAMTGRVFLPKPGGDK
HCCCEEECCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEECCHHHHHCCCEEEECCCCCH
IGRRRLDTHLLALQALGASIEVFPDGYEIKADQLKGTDILMDEASVTGTENAVMAAVFAE
HHHHHHHHHHHHHHHCCCEEEECCCCCEEECCCCCCCEEEEECCCCCCCCCCEEEEEHHC
GTTILRHAASEPHVQRLCHFLNSAGAKISGIGSNILTIEGVTSLKPPAKEHKIGSDYLEV
CHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCCEEEECCCCCCCCCHHHCCCCCHHHHH
GSFISLAAVTGGELMIRDVELEDIRMIRMVYSRLGIEVRPHENGILVPSDQKMEIIPDYH
HHHHEEEEECCCEEEEEECCHHHHHHHHHHHHHHCCEEEECCCCEEECCCCCEEECCCCC
GATPKIDDSPWPGFPADMTSVALVTATQCKGTVLIHEKMFESRLFFVDNIIAMGAQIILC
CCCCCCCCCCCCCCCCCHHHEEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEEE
DPHRAIVIGHSRLYGQKVASPDIRAGMAMIIAALCAEGTSYIHNIGQIDRGFENIDTRLR
CCCCEEEEECHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHH
ALGARIERVNAD
HHHHHHHHCCCC
>Mature Secondary Structure
MRSSYFKIIGKTPLHGTVVPQGNKNEALPLLGAVCMVPGTVRISNIPVISDVLMLMEVLR
CCCCEEEEEECCCCCCEECCCCCCCCCHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHH
HLGMEITEEEPGTYIFKHDGNLKNQLPEELCSRIRGAVTLAGPILAMTGRVFLPKPGGDK
HCCCEEECCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEECCHHHHHCCCEEEECCCCCH
IGRRRLDTHLLALQALGASIEVFPDGYEIKADQLKGTDILMDEASVTGTENAVMAAVFAE
HHHHHHHHHHHHHHHCCCEEEECCCCCEEECCCCCCCEEEEECCCCCCCCCCEEEEEHHC
GTTILRHAASEPHVQRLCHFLNSAGAKISGIGSNILTIEGVTSLKPPAKEHKIGSDYLEV
CHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCCEEEECCCCCCCCCHHHCCCCCHHHHH
GSFISLAAVTGGELMIRDVELEDIRMIRMVYSRLGIEVRPHENGILVPSDQKMEIIPDYH
HHHHEEEEECCCEEEEEECCHHHHHHHHHHHHHHCCEEEECCCCEEECCCCCEEECCCCC
GATPKIDDSPWPGFPADMTSVALVTATQCKGTVLIHEKMFESRLFFVDNIIAMGAQIILC
CCCCCCCCCCCCCCCCCHHHEEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEEE
DPHRAIVIGHSRLYGQKVASPDIRAGMAMIIAALCAEGTSYIHNIGQIDRGFENIDTRLR
CCCCEEEEECHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHH
ALGARIERVNAD
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA