| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
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The map label for this gene is sph [H]
Identifier: 45659020
GI number: 45659020
Start: 3920333
End: 3922009
Strand: Direct
Name: sph [H]
Synonym: LIC13198
Alternate gene names: 45659020
Gene position: 3920333-3922009 (Clockwise)
Preceding gene: 45659018
Following gene: 45659021
Centisome position: 91.66
GC content: 32.8
Gene sequence:
>1677_bases ATGAAAACAAAACGAAATCCCCTTCTAAACAAATGCAAAAAACCAAACAAATTTAAATATAGAAACCTATTAATTGGGCT TTTACTATGTTTATTCCCTCTAAATTGTACATTTAAAGATTCATTAGTATACAATAAATTTTTAATGTATATTTCATTTT CACATAAGAATTTAAATTTTGAATTAGAGAACATCAATTCAACTAGAAAGACCCTTTTACCAAAGTCAGAAATAGATTTA AATATTCTCAGTTATAATCTTTTTTTATATTCAAAAGAAGATATATATTTTGGATATTGGGAAGAAGAAAAAAGGGCGGA GCTTCTTGGAAAATCAAAATTTACAAAAAATCAGGACGTCATTGTACTCAGCAGAGTGTTTGATACAAATGCACGAAATA CTCTCCTAGACAATCTTAATTTAGAATATCCTGACCAAACCGACGTAATCGGAAAAACTAAGTATGGTTGGGATCAAACT CTCGGAGATTTTAGACAGCAGATCAACAACGGAGGAGTTGTCATTTTAAGTAAATGGCCTATTCAAGAAAAGATACAGTA TATCTTCAAAAATCATGGATGTGGTAATGACACATTCTACAATAAGGGTTTTGCTTACGTAAAAATTAAAAAAGGAAGTC AGATCATTCATATTGTAGGAACCGATACTCAATCGGAAGATTCGACATGTTCCGATTTAGGGGTAAATGCAAGAATCAAT CAGCTCACTGAAATTAAAAAATTTATCGATTCAAAACGTATATCCAACAAAGAAATCGTATTGATCGCGGGAGCTTTGAA CGTAGACAAAAGTAATCAATCTGAATATAAGAATATGCTTAATATACTAGAAGTAAACGAACCAAATTATGCAGGAATTC CATTTACATGGGACACGAAAAAAAACAAGATCGCTGCTTATAATAATATCTATTACTCCTGGAACCAGACCTCAAATTAC GGGGAATATATACTCGTTTCCAAAAATCACTTTCAACTTCCGATTTGGCAGAATTTAGCGTATGATCCGATTTCACCGAC TACGTGGAAAAGAAAAAATGGATATACAAGTTATGAATTTTCTGATCATTTCCCAATTTATGGTTTTGTTTACGCCGACC CTTCCACTCCTACAAAGTCAGGACACAGAAGAAAATACGATCAAGTTTCCTTAATAGCTAAATATACCGGAAAAGCAATA CAAGTGGATCATAATAGACCAGACGGATGGTTAAAAGCAGATGGAACTGCAAAAGAAAAAGGAACAGAATTTACAAAATT CAATTTACTGCAAGAATACGACCCTGATTCAGACACCTTTTGTATGTTAGGTGGGCGTGTAAGAATCGAATCTTCTCAAT ATTTAAATTACTTTTGGACTTGGTGGCTTAGAGGAGGAGGAGGTAACTATGCCTATTATCCTAAATTTGATGATAGCTCC AAACTACTCGAAATGATAATAATACGTCAAGGATGTTTAGAAGACGAAAGTTTGGTCGTATTTAAAGATTTTGATACATA CGGGAAATACTATTATTTTCTTGCAGTCTGGGAAAATGGAAGTTGGAAAGATTATATCTATCTTTGGTACACAAATGCCC AACCAAATTCGTACTTTATTGCTAAATTAAATACCTCACCTGAAAGAGATTGGAGCAAGGATCTAATTTATCGTTAG
Upstream 100 bases:
>100_bases AAATTTAAGCCAAATTTCCACTTAAGACGGAATTTGGACATTCTATTATATAACTCTGAGCAATATTAAATACAATAAAA TCACATATGGAGAATGTTAT
Downstream 100 bases:
>100_bases ATTTTATTTTACAAAAAGGAAATAAGATTTTTGTTTCCTTTTTGTAATATTTATAAAAAGGAATTGATTTTTTACTACTT TACTTGATTCTAACGGTTTC
Product: hemolysin/sphingomyelinase-like
Products: NA
Alternate protein names: Sphingomyelin phosphodiesterase; SMase [H]
Number of amino acids: Translated: 558; Mature: 558
Protein sequence:
>558_residues MKTKRNPLLNKCKKPNKFKYRNLLIGLLLCLFPLNCTFKDSLVYNKFLMYISFSHKNLNFELENINSTRKTLLPKSEIDL NILSYNLFLYSKEDIYFGYWEEEKRAELLGKSKFTKNQDVIVLSRVFDTNARNTLLDNLNLEYPDQTDVIGKTKYGWDQT LGDFRQQINNGGVVILSKWPIQEKIQYIFKNHGCGNDTFYNKGFAYVKIKKGSQIIHIVGTDTQSEDSTCSDLGVNARIN QLTEIKKFIDSKRISNKEIVLIAGALNVDKSNQSEYKNMLNILEVNEPNYAGIPFTWDTKKNKIAAYNNIYYSWNQTSNY GEYILVSKNHFQLPIWQNLAYDPISPTTWKRKNGYTSYEFSDHFPIYGFVYADPSTPTKSGHRRKYDQVSLIAKYTGKAI QVDHNRPDGWLKADGTAKEKGTEFTKFNLLQEYDPDSDTFCMLGGRVRIESSQYLNYFWTWWLRGGGGNYAYYPKFDDSS KLLEMIIIRQGCLEDESLVVFKDFDTYGKYYYFLAVWENGSWKDYIYLWYTNAQPNSYFIAKLNTSPERDWSKDLIYR
Sequences:
>Translated_558_residues MKTKRNPLLNKCKKPNKFKYRNLLIGLLLCLFPLNCTFKDSLVYNKFLMYISFSHKNLNFELENINSTRKTLLPKSEIDL NILSYNLFLYSKEDIYFGYWEEEKRAELLGKSKFTKNQDVIVLSRVFDTNARNTLLDNLNLEYPDQTDVIGKTKYGWDQT LGDFRQQINNGGVVILSKWPIQEKIQYIFKNHGCGNDTFYNKGFAYVKIKKGSQIIHIVGTDTQSEDSTCSDLGVNARIN QLTEIKKFIDSKRISNKEIVLIAGALNVDKSNQSEYKNMLNILEVNEPNYAGIPFTWDTKKNKIAAYNNIYYSWNQTSNY GEYILVSKNHFQLPIWQNLAYDPISPTTWKRKNGYTSYEFSDHFPIYGFVYADPSTPTKSGHRRKYDQVSLIAKYTGKAI QVDHNRPDGWLKADGTAKEKGTEFTKFNLLQEYDPDSDTFCMLGGRVRIESSQYLNYFWTWWLRGGGGNYAYYPKFDDSS KLLEMIIIRQGCLEDESLVVFKDFDTYGKYYYFLAVWENGSWKDYIYLWYTNAQPNSYFIAKLNTSPERDWSKDLIYR >Mature_558_residues MKTKRNPLLNKCKKPNKFKYRNLLIGLLLCLFPLNCTFKDSLVYNKFLMYISFSHKNLNFELENINSTRKTLLPKSEIDL NILSYNLFLYSKEDIYFGYWEEEKRAELLGKSKFTKNQDVIVLSRVFDTNARNTLLDNLNLEYPDQTDVIGKTKYGWDQT LGDFRQQINNGGVVILSKWPIQEKIQYIFKNHGCGNDTFYNKGFAYVKIKKGSQIIHIVGTDTQSEDSTCSDLGVNARIN QLTEIKKFIDSKRISNKEIVLIAGALNVDKSNQSEYKNMLNILEVNEPNYAGIPFTWDTKKNKIAAYNNIYYSWNQTSNY GEYILVSKNHFQLPIWQNLAYDPISPTTWKRKNGYTSYEFSDHFPIYGFVYADPSTPTKSGHRRKYDQVSLIAKYTGKAI QVDHNRPDGWLKADGTAKEKGTEFTKFNLLQEYDPDSDTFCMLGGRVRIESSQYLNYFWTWWLRGGGGNYAYYPKFDDSS KLLEMIIIRQGCLEDESLVVFKDFDTYGKYYYFLAVWENGSWKDYIYLWYTNAQPNSYFIAKLNTSPERDWSKDLIYR
Specific function: Unknown
COG id: NA
COG function: NA
Gene ontology:
Cell location: Secreted [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: NA
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005135 - InterPro: IPR017766 [H]
Pfam domain/function: PF03372 Exo_endo_phos [H]
EC number: =3.1.4.12 [H]
Molecular weight: Translated: 65337; Mature: 65337
Theoretical pI: Translated: 9.01; Mature: 9.01
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.3 %Cys (Translated Protein) 0.9 %Met (Translated Protein) 2.2 %Cys+Met (Translated Protein) 1.3 %Cys (Mature Protein) 0.9 %Met (Mature Protein) 2.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKTKRNPLLNKCKKPNKFKYRNLLIGLLLCLFPLNCTFKDSLVYNKFLMYISFSHKNLNF CCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHEEEEEEEEEECCCCEE ELENINSTRKTLLPKSEIDLNILSYNLFLYSKEDIYFGYWEEEKRAELLGKSKFTKNQDV EEECCCCHHHHCCCCCCCCEEEEEEEEEEEECCCEEEEECCCHHHHHHHCCCCCCCCCCE IVLSRVFDTNARNTLLDNLNLEYPDQTDVIGKTKYGWDQTLGDFRQQINNGGVVILSKWP EEEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCC IQEKIQYIFKNHGCGNDTFYNKGFAYVKIKKGSQIIHIVGTDTQSEDSTCSDLGVNARIN HHHHHHHHHHCCCCCCCCEECCCEEEEEEECCCEEEEEEECCCCCCCCCHHHCCCCCHHH QLTEIKKFIDSKRISNKEIVLIAGALNVDKSNQSEYKNMLNILEVNEPNYAGIPFTWDTK HHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHEEEEECCCCCCCCEEEECCC KNKIAAYNNIYYSWNQTSNYGEYILVSKNHFQLPIWQNLAYDPISPTTWKRKNGYTSYEF CCEEEEEEEEEEEECCCCCCCCEEEEECCCEECCHHHCCCCCCCCCCCEECCCCEEEEEE SDHFPIYGFVYADPSTPTKSGHRRKYDQVSLIAKYTGKAIQVDHNRPDGWLKADGTAKEK CCCCCEEEEEEECCCCCCCCCCCCCCHHHEEEEECCCCEEEEECCCCCCCEECCCCCCCC GTEFTKFNLLQEYDPDSDTFCMLGGRVRIESSQYLNYFWTWWLRGGGGNYAYYPKFDDSS CCCEEEEEHHHHCCCCCCEEEEECCEEEEECCCCEEEEEEEEEECCCCCEEECCCCCCHH KLLEMIIIRQGCLEDESLVVFKDFDTYGKYYYFLAVWENGSWKDYIYLWYTNAQPNSYFI HHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEEEEECCCCCEEEEEEEECCCCCEEEE AKLNTSPERDWSKDLIYR EEECCCCCCCCCHHHCCC >Mature Secondary Structure MKTKRNPLLNKCKKPNKFKYRNLLIGLLLCLFPLNCTFKDSLVYNKFLMYISFSHKNLNF CCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEHHHHHEEEEEEEEEECCCCEE ELENINSTRKTLLPKSEIDLNILSYNLFLYSKEDIYFGYWEEEKRAELLGKSKFTKNQDV EEECCCCHHHHCCCCCCCCEEEEEEEEEEEECCCEEEEECCCHHHHHHHCCCCCCCCCCE IVLSRVFDTNARNTLLDNLNLEYPDQTDVIGKTKYGWDQTLGDFRQQINNGGVVILSKWP EEEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCC IQEKIQYIFKNHGCGNDTFYNKGFAYVKIKKGSQIIHIVGTDTQSEDSTCSDLGVNARIN HHHHHHHHHHCCCCCCCCEECCCEEEEEEECCCEEEEEEECCCCCCCCCHHHCCCCCHHH QLTEIKKFIDSKRISNKEIVLIAGALNVDKSNQSEYKNMLNILEVNEPNYAGIPFTWDTK HHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHEEEEECCCCCCCCEEEECCC KNKIAAYNNIYYSWNQTSNYGEYILVSKNHFQLPIWQNLAYDPISPTTWKRKNGYTSYEF CCEEEEEEEEEEEECCCCCCCCEEEEECCCEECCHHHCCCCCCCCCCCEECCCCEEEEEE SDHFPIYGFVYADPSTPTKSGHRRKYDQVSLIAKYTGKAIQVDHNRPDGWLKADGTAKEK CCCCCEEEEEEECCCCCCCCCCCCCCHHHEEEEECCCCEEEEECCCCCCCEECCCCCCCC GTEFTKFNLLQEYDPDSDTFCMLGGRVRIESSQYLNYFWTWWLRGGGGNYAYYPKFDDSS CCCEEEEEHHHHCCCCCCEEEEECCEEEEECCCCEEEEEEEEEECCCCCEEECCCCCCHH KLLEMIIIRQGCLEDESLVVFKDFDTYGKYYYFLAVWENGSWKDYIYLWYTNAQPNSYFI HHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEEEEECCCCCEEEEEEEECCCCCEEEE AKLNTSPERDWSKDLIYR EEECCCCCCCCCHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 2163985 [H]