| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
Click here to switch to the map view.
The map label for this gene is rpfC [H]
Identifier: 45659014
GI number: 45659014
Start: 3907493
End: 3909961
Strand: Reverse
Name: rpfC [H]
Synonym: LIC13192
Alternate gene names: 45659014
Gene position: 3909961-3907493 (Counterclockwise)
Preceding gene: 45659015
Following gene: 45659012
Centisome position: 91.41
GC content: 32.81
Gene sequence:
>2469_bases TTGAATATGAGATTTTTATTATTATATATCATATTTCTATTTCATTATTCTCTAATGGCCGAGTCTTTATCTCCGGTTTC GGGAAAAATTTCACAATTACAGAAAGATTCTTCTTTAAGTTTTTTTGTATATTACTTTAGCAGTGACTCGGATGAAAATT TTCGAGAAAGAATTTTTGCAAAGGATTCTTCTCTTTCTTTTCAAAACATTCCTGCAGAAGTGTTTTCACTCGGTTTTACA AGTAATACTGCCTGGTTTTATATTCCTTTAAAAAACGATACCAAAAAAGATTACCGAGGAGAATTCGAAATTTTTAATCC TTATTTGGAAGAAGTAGATATTTTCTATCGATACGGTTCTAAGGATTCAATTCATGAAATTCTCGCGGGAACAAGTCGTG TTTACGAAAAAAGTTTTCCTGCACTCAATTTTTACCTTCGTCCTGGGGAAGAAATTCAAATCGTTTGTAAGATCAAAAGT GGAACTCCTATGCGAATTCCTATTGTGTTGGAGTCGGAAGAAAATTTCAATTTTACAAAACTATTTAGAGCGATTCTATT CGGATTAACCTTAGGGTTTGGAATCGCGATGGGTTTGTATAATTTTTCATTGTACATGTTTTTTAGAACGAGATCATACT TATATTATTTTATTATGATTTTATTTTCTACGGTTTATTTGACTTCTTGGGACGGATTAATTTCTCCTCTTTTTAAACCA AATTATGGAAGATATTATCTTCCATTTATACTGGTCCTTTTTTATACTTCCGCTTTGTTTCTTTTTCTTTTTTCTATGGA ATTTTTATATCCTGAAAAAAAAGAAAGATATGTAAAAATTATAATATTTTTATATGTAGTTGTCAATTTGCTTTTAATAC CTCTCTCCATTTTTTATCCTACTCACTTAAATCGGATTTCGTATTATCTGGGATTGGTTAATAATCTAATCATTGTTTAT TTTTGTATTGTGAGAATTAGAGGTGGTTTTAAGTCTGCAAAAAATTTTCTAATCATTCATCTTGTATTTCCTGTCGCTGG AATCCTCACAAATTTAAGTACGTTCGGAGCGATTTCGATCGATTATCTTTCGCTTCATCTACTAAAATTGGCGTTTATTT CTCAGTCCGTTCTTTTTTCGGTTATGCTCGTCCAGAGAATTAAAGAATTGGAATTTAGACTTAAGGATGGTTTACAATCT GAGATTCATAAAAACATTGTACTCCTTAAAAAAGAAATTCAACAAAGAAGAGAAACTGAATGGGAATTAATACAGGCCAA AGAGGTCGCCGAAAAAGCTTCTAAGGTCAAAAGTAATTTTCTTGCAAACATGAGTCACGAAATTCGGACTCCGATGAACG GCGTTTTAGGAATGGTTCAGCTTTTGGGAACAACTAAACTCAACGACGAACAAAAAGAATATGTCGAAGTTCTTTCTGTT TCCGCCAAATCGTTGTTACAAATTATCAACGATATTTTAGATTTTTCTAAAATTGAAGCTGGAAAAGTTATCTTGGAAAG AGAAGTTTTTTCGATTCGTTCTGTTTTGGATGAAATTCACGATCTTTTATATCCTCTTGCAAAACAGAAAGAGATCAATT TTCGTTTAGAAGGTAAATTAGAAATTCAAGAATACGTTTATGGAGATCCTCTTAGACTTCGACAAATTTTATGGAATCTT GCAGGTAATGGAATTAAATTTACGAGTCGCGGAGAAGTGGTTCTTAAGGTGACTCAAAAAAATATTTCTAAAAGTAGCGT ATCCATAGAGTTTACGGTTATGGATTCAGGAATCGGAATTCCTTTGGAAAAACAAAAACAAGTCTTCGAAGCGTTTTCTC AAAATGATACGTCTACCGCCAGAAAGTTCGGAGGTTCTGGTTTGGGACTTAGCATCACAAAACAACTCGTGGAACTTCAA GGTGGAGTTTTGAAATTAGAAAGTAAGGATGGTGAGGGCTCTAAGTTTACGTTCACGATTGATTATGATATTCCTTCAGC TTTGGAAATAGAAAAAATTCTTGAAGCGGAAAAGACTAAGGATCTGGAAAAATCTTTTCAAGATGTTGTTGCTAAAAGCA CTCGAATTCTGGTTGCAGAGGATAATGAAACGAATTGTCTTTTGATCGAAAGAGCTCTTAAAAAATTAGGATATGATCCG ACGGTAGTGCATAACGGTAGGGAAGTAATTGAAAGAATGCAGTTGGAAGCTTTTGATATAATTCTTATGGATATTCATAT GCCGGAAGTGGATGGAATTGAAGCTACAAAATGGATTCGTTCAAAAAATCAAAATTCGGAATTTCCTATTATCATCGCTT TGACAGCGGATGCAATTGAAAGTAGTAAAGAAAAATATATTTCTAAAGGAATGAATGATTGTTTAACTAAACCTTTGGAT TTGCCAATTCTTAAAAGTACTCTTGATTTATGGTCTAATCGAGTAGACGTCTCTCATTGGAAGTTGTAA
Upstream 100 bases:
>100_bases TGATAAAATCAATAGGAGTAAAAAAAGATTTTTACTCCTAAAATAGATTTCGTAGAATAGATCCAAAATCGCCTTTCCCA GTTTTTCGGTTTTTACTTTT
Downstream 100 bases:
>100_bases GTAGCAATTTTATTGAGTGTAAATTTTACGTAAAAAAATTTTGGATTCTCTTTCGTCGTAAATATATGTTCAAAAAATTT TTTGCTTTCTGTAGATCATT
Product: histidine kinase response regulator hybrid protein
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 822; Mature: 822
Protein sequence:
>822_residues MNMRFLLLYIIFLFHYSLMAESLSPVSGKISQLQKDSSLSFFVYYFSSDSDENFRERIFAKDSSLSFQNIPAEVFSLGFT SNTAWFYIPLKNDTKKDYRGEFEIFNPYLEEVDIFYRYGSKDSIHEILAGTSRVYEKSFPALNFYLRPGEEIQIVCKIKS GTPMRIPIVLESEENFNFTKLFRAILFGLTLGFGIAMGLYNFSLYMFFRTRSYLYYFIMILFSTVYLTSWDGLISPLFKP NYGRYYLPFILVLFYTSALFLFLFSMEFLYPEKKERYVKIIIFLYVVVNLLLIPLSIFYPTHLNRISYYLGLVNNLIIVY FCIVRIRGGFKSAKNFLIIHLVFPVAGILTNLSTFGAISIDYLSLHLLKLAFISQSVLFSVMLVQRIKELEFRLKDGLQS EIHKNIVLLKKEIQQRRETEWELIQAKEVAEKASKVKSNFLANMSHEIRTPMNGVLGMVQLLGTTKLNDEQKEYVEVLSV SAKSLLQIINDILDFSKIEAGKVILEREVFSIRSVLDEIHDLLYPLAKQKEINFRLEGKLEIQEYVYGDPLRLRQILWNL AGNGIKFTSRGEVVLKVTQKNISKSSVSIEFTVMDSGIGIPLEKQKQVFEAFSQNDTSTARKFGGSGLGLSITKQLVELQ GGVLKLESKDGEGSKFTFTIDYDIPSALEIEKILEAEKTKDLEKSFQDVVAKSTRILVAEDNETNCLLIERALKKLGYDP TVVHNGREVIERMQLEAFDIILMDIHMPEVDGIEATKWIRSKNQNSEFPIIIALTADAIESSKEKYISKGMNDCLTKPLD LPILKSTLDLWSNRVDVSHWKL
Sequences:
>Translated_822_residues MNMRFLLLYIIFLFHYSLMAESLSPVSGKISQLQKDSSLSFFVYYFSSDSDENFRERIFAKDSSLSFQNIPAEVFSLGFT SNTAWFYIPLKNDTKKDYRGEFEIFNPYLEEVDIFYRYGSKDSIHEILAGTSRVYEKSFPALNFYLRPGEEIQIVCKIKS GTPMRIPIVLESEENFNFTKLFRAILFGLTLGFGIAMGLYNFSLYMFFRTRSYLYYFIMILFSTVYLTSWDGLISPLFKP NYGRYYLPFILVLFYTSALFLFLFSMEFLYPEKKERYVKIIIFLYVVVNLLLIPLSIFYPTHLNRISYYLGLVNNLIIVY FCIVRIRGGFKSAKNFLIIHLVFPVAGILTNLSTFGAISIDYLSLHLLKLAFISQSVLFSVMLVQRIKELEFRLKDGLQS EIHKNIVLLKKEIQQRRETEWELIQAKEVAEKASKVKSNFLANMSHEIRTPMNGVLGMVQLLGTTKLNDEQKEYVEVLSV SAKSLLQIINDILDFSKIEAGKVILEREVFSIRSVLDEIHDLLYPLAKQKEINFRLEGKLEIQEYVYGDPLRLRQILWNL AGNGIKFTSRGEVVLKVTQKNISKSSVSIEFTVMDSGIGIPLEKQKQVFEAFSQNDTSTARKFGGSGLGLSITKQLVELQ GGVLKLESKDGEGSKFTFTIDYDIPSALEIEKILEAEKTKDLEKSFQDVVAKSTRILVAEDNETNCLLIERALKKLGYDP TVVHNGREVIERMQLEAFDIILMDIHMPEVDGIEATKWIRSKNQNSEFPIIIALTADAIESSKEKYISKGMNDCLTKPLD LPILKSTLDLWSNRVDVSHWKL >Mature_822_residues MNMRFLLLYIIFLFHYSLMAESLSPVSGKISQLQKDSSLSFFVYYFSSDSDENFRERIFAKDSSLSFQNIPAEVFSLGFT SNTAWFYIPLKNDTKKDYRGEFEIFNPYLEEVDIFYRYGSKDSIHEILAGTSRVYEKSFPALNFYLRPGEEIQIVCKIKS GTPMRIPIVLESEENFNFTKLFRAILFGLTLGFGIAMGLYNFSLYMFFRTRSYLYYFIMILFSTVYLTSWDGLISPLFKP NYGRYYLPFILVLFYTSALFLFLFSMEFLYPEKKERYVKIIIFLYVVVNLLLIPLSIFYPTHLNRISYYLGLVNNLIIVY FCIVRIRGGFKSAKNFLIIHLVFPVAGILTNLSTFGAISIDYLSLHLLKLAFISQSVLFSVMLVQRIKELEFRLKDGLQS EIHKNIVLLKKEIQQRRETEWELIQAKEVAEKASKVKSNFLANMSHEIRTPMNGVLGMVQLLGTTKLNDEQKEYVEVLSV SAKSLLQIINDILDFSKIEAGKVILEREVFSIRSVLDEIHDLLYPLAKQKEINFRLEGKLEIQEYVYGDPLRLRQILWNL AGNGIKFTSRGEVVLKVTQKNISKSSVSIEFTVMDSGIGIPLEKQKQVFEAFSQNDTSTARKFGGSGLGLSITKQLVELQ GGVLKLESKDGEGSKFTFTIDYDIPSALEIEKILEAEKTKDLEKSFQDVVAKSTRILVAEDNETNCLLIERALKKLGYDP TVVHNGREVIERMQLEAFDIILMDIHMPEVDGIEATKWIRSKNQNSEFPIIIALTADAIESSKEKYISKGMNDCLTKPLD LPILKSTLDLWSNRVDVSHWKL
Specific function: Involved in the positive regulation of synthesis of extracellular enzymes and polysaccharide, and hence in pathogenicity. Can restore function to the non-pathogenic mutant 8237 [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 response regulatory domain [H]
Homologues:
Organism=Escherichia coli, GI1789149, Length=274, Percent_Identity=43.7956204379562, Blast_Score=228, Evalue=8e-61, Organism=Escherichia coli, GI48994928, Length=394, Percent_Identity=32.994923857868, Blast_Score=228, Evalue=2e-60, Organism=Escherichia coli, GI1788713, Length=392, Percent_Identity=36.9897959183673, Blast_Score=222, Evalue=8e-59, Organism=Escherichia coli, GI87081816, Length=436, Percent_Identity=30.5045871559633, Blast_Score=172, Evalue=1e-43, Organism=Escherichia coli, GI145693157, Length=249, Percent_Identity=36.9477911646586, Blast_Score=161, Evalue=2e-40, Organism=Escherichia coli, GI1786783, Length=227, Percent_Identity=28.6343612334802, Blast_Score=97, Evalue=6e-21, Organism=Escherichia coli, GI1786600, Length=260, Percent_Identity=26.9230769230769, Blast_Score=96, Evalue=9e-21, Organism=Escherichia coli, GI1788549, Length=248, Percent_Identity=25.8064516129032, Blast_Score=90, Evalue=6e-19, Organism=Escherichia coli, GI1790436, Length=228, Percent_Identity=25.8771929824561, Blast_Score=84, Evalue=3e-17, Organism=Escherichia coli, GI1786912, Length=249, Percent_Identity=24.0963855421687, Blast_Score=82, Evalue=1e-16, Organism=Escherichia coli, GI87082128, Length=235, Percent_Identity=26.3829787234043, Blast_Score=75, Evalue=2e-14, Organism=Escherichia coli, GI1788393, Length=220, Percent_Identity=25.4545454545455, Blast_Score=75, Evalue=2e-14, Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=1e-13, Organism=Escherichia coli, GI1788279, Length=206, Percent_Identity=26.2135922330097, Blast_Score=71, Evalue=3e-13, Organism=Escherichia coli, GI1790346, Length=221, Percent_Identity=27.1493212669683, Blast_Score=70, Evalue=4e-13, Organism=Escherichia coli, GI1788545, Length=239, Percent_Identity=23.0125523012552, Blast_Score=65, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6322044, Length=74, Percent_Identity=52.7027027027027, Blast_Score=76, Evalue=2e-14,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003594 - InterPro: IPR011006 - InterPro: IPR004358 - InterPro: IPR008207 - InterPro: IPR003661 - InterPro: IPR005467 - InterPro: IPR009082 - InterPro: IPR001789 [H]
Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]
EC number: =2.7.13.3 [H]
Molecular weight: Translated: 94583; Mature: 94583
Theoretical pI: Translated: 7.35; Mature: 7.35
Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 2.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNMRFLLLYIIFLFHYSLMAESLSPVSGKISQLQKDSSLSFFVYYFSSDSDENFRERIFA CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHH KDSSLSFQNIPAEVFSLGFTSNTAWFYIPLKNDTKKDYRGEFEIFNPYLEEVDIFYRYGS CCCCCCHHCCCHHHHEECCCCCCEEEEEECCCCCCHHHCCCCEEECHHHHHHHHHHCCCC KDSIHEILAGTSRVYEKSFPALNFYLRPGEEIQIVCKIKSGTPMRIPIVLESEENFNFTK CCHHHHHHHCHHHHHHHCCCCEEEEECCCCCEEEEEEECCCCCEEEEEEEECCCCCCHHH LFRAILFGLTLGFGIAMGLYNFSLYMFFRTRSYLYYFIMILFSTVYLTSWDGLISPLFKP HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCC NYGRYYLPFILVLFYTSALFLFLFSMEFLYPEKKERYVKIIIFLYVVVNLLLIPLSIFYP CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH THLNRISYYLGLVNNLIIVYFCIVRIRGGFKSAKNFLIIHLVFPVAGILTNLSTFGAISI HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCHH DYLSLHLLKLAFISQSVLFSVMLVQRIKELEFRLKDGLQSEIHKNIVLLKKEIQQRRETE HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCH WELIQAKEVAEKASKVKSNFLANMSHEIRTPMNGVLGMVQLLGTTKLNDEQKEYVEVLSV HHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHH SAKSLLQIINDILDFSKIEAGKVILEREVFSIRSVLDEIHDLLYPLAKQKEINFRLEGKL HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCE EIQEYVYGDPLRLRQILWNLAGNGIKFTSRGEVVLKVTQKNISKSSVSIEFTVMDSGIGI EEHHHHCCCHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCCCCCEEEEEEEEECCCCC PLEKQKQVFEAFSQNDTSTARKFGGSGLGLSITKQLVELQGGVLKLESKDGEGSKFTFTI CCHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCEEEEEE DYDIPSALEIEKILEAEKTKDLEKSFQDVVAKSTRILVAEDNETNCLLIERALKKLGYDP ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEHHHHHHHHCCCCC TVVHNGREVIERMQLEAFDIILMDIHMPEVDGIEATKWIRSKNQNSEFPIIIALTADAIE EEEECCHHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHCCCCCCCCCEEEEEEHHHHH SSKEKYISKGMNDCLTKPLDLPILKSTLDLWSNRVDVSHWKL HHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHCCCCCCHHCCC >Mature Secondary Structure MNMRFLLLYIIFLFHYSLMAESLSPVSGKISQLQKDSSLSFFVYYFSSDSDENFRERIFA CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHH KDSSLSFQNIPAEVFSLGFTSNTAWFYIPLKNDTKKDYRGEFEIFNPYLEEVDIFYRYGS CCCCCCHHCCCHHHHEECCCCCCEEEEEECCCCCCHHHCCCCEEECHHHHHHHHHHCCCC KDSIHEILAGTSRVYEKSFPALNFYLRPGEEIQIVCKIKSGTPMRIPIVLESEENFNFTK CCHHHHHHHCHHHHHHHCCCCEEEEECCCCCEEEEEEECCCCCEEEEEEEECCCCCCHHH LFRAILFGLTLGFGIAMGLYNFSLYMFFRTRSYLYYFIMILFSTVYLTSWDGLISPLFKP HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCC NYGRYYLPFILVLFYTSALFLFLFSMEFLYPEKKERYVKIIIFLYVVVNLLLIPLSIFYP CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH THLNRISYYLGLVNNLIIVYFCIVRIRGGFKSAKNFLIIHLVFPVAGILTNLSTFGAISI HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCHH DYLSLHLLKLAFISQSVLFSVMLVQRIKELEFRLKDGLQSEIHKNIVLLKKEIQQRRETE HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCH WELIQAKEVAEKASKVKSNFLANMSHEIRTPMNGVLGMVQLLGTTKLNDEQKEYVEVLSV HHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHH SAKSLLQIINDILDFSKIEAGKVILEREVFSIRSVLDEIHDLLYPLAKQKEINFRLEGKL HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCE EIQEYVYGDPLRLRQILWNLAGNGIKFTSRGEVVLKVTQKNISKSSVSIEFTVMDSGIGI EEHHHHCCCHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCCCCCEEEEEEEEECCCCC PLEKQKQVFEAFSQNDTSTARKFGGSGLGLSITKQLVELQGGVLKLESKDGEGSKFTFTI CCHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCEEEEEE DYDIPSALEIEKILEAEKTKDLEKSFQDVVAKSTRILVAEDNETNCLLIERALKKLGYDP ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEHHHHHHHHCCCCC TVVHNGREVIERMQLEAFDIILMDIHMPEVDGIEATKWIRSKNQNSEFPIIIALTADAIE EEEECCHHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHCCCCCCCCCEEEEEEHHHHH SSKEKYISKGMNDCLTKPLDLPILKSTLDLWSNRVDVSHWKL HHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHCCCCCCHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 1645442 [H]