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The map label for this gene is tas

Identifier: 45658998

GI number: 45658998

Start: 3888014

End: 3889081

Strand: Reverse

Name: tas

Synonym: LIC13176

Alternate gene names: 45658998

Gene position: 3889081-3888014 (Counterclockwise)

Preceding gene: 45659000

Following gene: 45658992

Centisome position: 90.93

GC content: 39.42

Gene sequence:

>1068_bases
TTGCCTTTGTCGATAAAAGGCTCATTTTTGACTTTAAATGGAGGAATAGAATTGAAAAAAAGAAGACTGGGAAAATCAGG
TATGGTCGTTTCTGAAATCTGTATGGGAACGATGACCTTTGGATCTACTTGTGACGAGGTGGAGGCGTTCCGTATTTTAG
ATAGGGCTTACGACGCGGGAATCGATTTTTACGATACGGCTGAAGTTTATCCAGTTCCACCTGATGCTAGTTATGTGCAT
GAGACGGAAAGAATTTTTGGAAAGTGGTTAAAGACCAAAAAAAGAGATTCTATTTTGATCGCCACTAAGGTCTGCGGTCC
TGGACACGGTTGGTTTGCCCCTCCAGTTAGAGAAGGAAAAACGGCGTTGGATCGGAAAAATATCCGAACTGCGATTGAAG
GAAGTCTTAGACGTTTGGGAACTGATTTTGTAGATCTTTATCAAACACATTGGCCGGATCATGATTTCGGTTATGAAGAA
ACTCTACAAGTTTTGACGGAACTAATTAAAGAAGGAAAAGTTCGTTATATCGGTAACAGTAATGAAACTGCGTGGGGAAT
GATGAAAAGTCTTTCTATTTCCGAAAAATTTAGTTTGTCACGTTATGAGTCCATTCAGAATAATTTTAGTATATTAAACC
GAAGATTTGAGGACGCGTTATCCGATATATGCAAAAAAGAAGGTGTGAGTCTTTTGCCTTATTCTCCGATTGCGGGTGGA
GTTCTTTCGGGAAAATACAATTCTTCTAATCCTCCTCAGAACGCTAGATTTAGCCGTTATCTAAATTCTGGTGAAAGGCA
AAAAAAAATGGCTCATCGTTTTTTAAACGAAGGCACATTGGCTTCTACCCAAAAATTAATGAAGATCGCGCAAGAAGCTG
GAATGTCAGTTACGGTTCTTGCGGTGGCCTGGTCTAAACAACACGACTACGTTGCTTCTACAATTATCGGAGCGAATACA
GTGGAACAATTGGAAGAAAGTTTAAAGGCTAAGAACGTGATTTTATCAGAGGATGTTTTAAAAAAGATAGACGAGGTTTC
CAAAGAAATACCTTATCCAATGGGATAG

Upstream 100 bases:

>100_bases
TAGTTATCTATAGGAAACGTCAAATTTTTTAGTTCTTTTTAAATGCGGTAACCAATTCTTATAATTTGTTTTTCAAATGT
TGGTTTGAAAACGTTTCGGA

Downstream 100 bases:

>100_bases
GCGTTCGTAAACTGTTTGATACTTTCGGACTTTCCGAATAGGATCAGAATTTCTTTCTCTCGAAATATCGTTCTAGAATT
GGGGAGAAACACTCCCCCTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MPLSIKGSFLTLNGGIELKKRRLGKSGMVVSEICMGTMTFGSTCDEVEAFRILDRAYDAGIDFYDTAEVYPVPPDASYVH
ETERIFGKWLKTKKRDSILIATKVCGPGHGWFAPPVREGKTALDRKNIRTAIEGSLRRLGTDFVDLYQTHWPDHDFGYEE
TLQVLTELIKEGKVRYIGNSNETAWGMMKSLSISEKFSLSRYESIQNNFSILNRRFEDALSDICKKEGVSLLPYSPIAGG
VLSGKYNSSNPPQNARFSRYLNSGERQKKMAHRFLNEGTLASTQKLMKIAQEAGMSVTVLAVAWSKQHDYVASTIIGANT
VEQLEESLKAKNVILSEDVLKKIDEVSKEIPYPMG

Sequences:

>Translated_355_residues
MPLSIKGSFLTLNGGIELKKRRLGKSGMVVSEICMGTMTFGSTCDEVEAFRILDRAYDAGIDFYDTAEVYPVPPDASYVH
ETERIFGKWLKTKKRDSILIATKVCGPGHGWFAPPVREGKTALDRKNIRTAIEGSLRRLGTDFVDLYQTHWPDHDFGYEE
TLQVLTELIKEGKVRYIGNSNETAWGMMKSLSISEKFSLSRYESIQNNFSILNRRFEDALSDICKKEGVSLLPYSPIAGG
VLSGKYNSSNPPQNARFSRYLNSGERQKKMAHRFLNEGTLASTQKLMKIAQEAGMSVTVLAVAWSKQHDYVASTIIGANT
VEQLEESLKAKNVILSEDVLKKIDEVSKEIPYPMG
>Mature_354_residues
PLSIKGSFLTLNGGIELKKRRLGKSGMVVSEICMGTMTFGSTCDEVEAFRILDRAYDAGIDFYDTAEVYPVPPDASYVHE
TERIFGKWLKTKKRDSILIATKVCGPGHGWFAPPVREGKTALDRKNIRTAIEGSLRRLGTDFVDLYQTHWPDHDFGYEET
LQVLTELIKEGKVRYIGNSNETAWGMMKSLSISEKFSLSRYESIQNNFSILNRRFEDALSDICKKEGVSLLPYSPIAGGV
LSGKYNSSNPPQNARFSRYLNSGERQKKMAHRFLNEGTLASTQKLMKIAQEAGMSVTVLAVAWSKQHDYVASTIIGANTV
EQLEESLKAKNVILSEDVLKKIDEVSKEIPYPMG

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=341, Percent_Identity=31.9648093841642, Blast_Score=154, Evalue=8e-38,
Organism=Homo sapiens, GI4504825, Length=341, Percent_Identity=31.9648093841642, Blast_Score=154, Evalue=8e-38,
Organism=Homo sapiens, GI27436964, Length=344, Percent_Identity=31.3953488372093, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI27436962, Length=341, Percent_Identity=31.3782991202346, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI27436966, Length=344, Percent_Identity=31.1046511627907, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI27436971, Length=344, Percent_Identity=30.2325581395349, Blast_Score=131, Evalue=7e-31,
Organism=Homo sapiens, GI223718702, Length=218, Percent_Identity=28.8990825688073, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI41327764, Length=222, Percent_Identity=28.8288288288288, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI41152114, Length=219, Percent_Identity=27.8538812785388, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI1789199, Length=357, Percent_Identity=38.9355742296919, Blast_Score=234, Evalue=9e-63,
Organism=Escherichia coli, GI87081735, Length=341, Percent_Identity=31.3782991202346, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1789375, Length=335, Percent_Identity=29.5522388059701, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1788070, Length=334, Percent_Identity=27.8443113772455, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1787674, Length=339, Percent_Identity=24.4837758112094, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1788081, Length=313, Percent_Identity=26.517571884984, Blast_Score=71, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6325169, Length=351, Percent_Identity=28.2051282051282, Blast_Score=135, Evalue=9e-33,
Organism=Saccharomyces cerevisiae, GI6323998, Length=343, Percent_Identity=26.2390670553936, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6319958, Length=327, Percent_Identity=26.605504587156, Blast_Score=119, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6319951, Length=342, Percent_Identity=25.7309941520468, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6322615, Length=268, Percent_Identity=25.3731343283582, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6321052, Length=168, Percent_Identity=30.952380952381, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24646155, Length=172, Percent_Identity=33.1395348837209, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 39716; Mature: 39585

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLSIKGSFLTLNGGIELKKRRLGKSGMVVSEICMGTMTFGSTCDEVEAFRILDRAYDAG
CCCEECCCEEEECCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
IDFYDTAEVYPVPPDASYVHETERIFGKWLKTKKRDSILIATKVCGPGHGWFAPPVREGK
CCCCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHCCH
TALDRKNIRTAIEGSLRRLGTDFVDLYQTHWPDHDFGYEETLQVLTELIKEGKVRYIGNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEECCC
NETAWGMMKSLSISEKFSLSRYESIQNNFSILNRRFEDALSDICKKEGVSLLPYSPIAGG
CCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
VLSGKYNSSNPPQNARFSRYLNSGERQKKMAHRFLNEGTLASTQKLMKIAQEAGMSVTVL
CEECCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEE
AVAWSKQHDYVASTIIGANTVEQLEESLKAKNVILSEDVLKKIDEVSKEIPYPMG
EEEECCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PLSIKGSFLTLNGGIELKKRRLGKSGMVVSEICMGTMTFGSTCDEVEAFRILDRAYDAG
CCEECCCEEEECCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
IDFYDTAEVYPVPPDASYVHETERIFGKWLKTKKRDSILIATKVCGPGHGWFAPPVREGK
CCCCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHCCH
TALDRKNIRTAIEGSLRRLGTDFVDLYQTHWPDHDFGYEETLQVLTELIKEGKVRYIGNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEECCC
NETAWGMMKSLSISEKFSLSRYESIQNNFSILNRRFEDALSDICKKEGVSLLPYSPIAGG
CCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
VLSGKYNSSNPPQNARFSRYLNSGERQKKMAHRFLNEGTLASTQKLMKIAQEAGMSVTVL
CEECCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEE
AVAWSKQHDYVASTIIGANTVEQLEESLKAKNVILSEDVLKKIDEVSKEIPYPMG
EEEECCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]