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The map label for this gene is pgi

Identifier: 45658928

GI number: 45658928

Start: 3798330

End: 3799667

Strand: Direct

Name: pgi

Synonym: LIC13105

Alternate gene names: 45658928

Gene position: 3798330-3799667 (Clockwise)

Preceding gene: 45658923

Following gene: 45658929

Centisome position: 88.8

GC content: 37.52

Gene sequence:

>1338_bases
ATGATTCGACTAGAAACCAGATTCGCTTCTTCTTTTATACAATCCTCTAAACTCGAACCTTTTTTAGAGAAGTCAGAATC
GGCCCGACTTACACTTCACTCCTCTCAAGGACAAGGAAAAGAATACTTAGGATGGTTGTATCTCCCCAAAGAGTTGAAAA
ATTCAGAAATCGAAAGAATGACTCAAGTCGCAGAACGCTTAAGAAATTCTTCGGAAGTAATCGTAGTGATAGGAATCGGA
GGTTCTTATTTAGGATCGCGCGCCGTATTGGAAGCCACACTTCCATTTTTCAAAAAACCTTCCATCGGAAATCCAGAAAT
TATTTTTGCAGGACATCATCTCGAATCTAGATATTTTTCTGAACTAATAGAATATCTCGAAGATAAAAATTTTTCGATCA
ATGTCATCTCTAAGTCAGGAACAACCACGGAACCTGCCATTGCATTTCGTCTTCTTTGGGAACTTCTTCGTAAAAAATAT
GGTTCTTCTGCATCTTCCAGAGTAGTCGCTACCACAGATTCATCCAAAGGAGTTCTAAAAAAATTTGCGGATTCGGAAAA
ACTCGATACGTTTACAATTCCAGATAACGTTGGCGGAAGATATTCCGTCTTAACCCCCGTAGGTTTATTTCCTCTTGCAG
TCGCCGGAATTTCGATCAGTAAATTTATATTAGGATTTCAAAATATTCTAAATGATATTCATTCAATTACTGATCCTACC
CGCAACCCTGCTACTTATTATTCCGCATTAAGAAATTATTTTTTATCCGAAGGAAGATATATAGAAGTATTAGCAAATTT
TAATCCTTCTCTCCGATACGTTTCAGAATGGTGGAAACAATTGTTTGGTGAAAGTGAAGGAAAAGAAAACAAAGGAATTT
TTCCGGCTTCTATGGATTTCACTACCGATCTACATTCTTTAGGGCAATACATCCAAGAAGGAAAACGTATTTTATTCGAG
ACGGTTCTAAGCCCTTCCGAAGTTTGCTCAAATCTGACCTTGAAACCAACTCAAGACAATTTAGATTCTTTGAATTTTCT
TTCAGGAAATACCCTCGGATACGTAAACGAACAAGCAAGATTAGGAACTCTACTTGCCCATGCGGACGGTGGAGTACCTT
GTTTAGAACTTGTATTTCCGGACATATCTCCTCAATCCTTGGGAGAATTGATGTATTTTTTTGAATATTCCTGTGCAATT
TCAGGTTACTCCTTGGGAGTGAACCCATTTGATCAACCTGGAGTAGAAGCGTATAAAAAAAATATGTTCGCTCTTTTAAA
TAAACCAGGTTTTGAGCAAGAAGGAGAAACACTTCGCAAAAGAATTTCAAGGAACTAA

Upstream 100 bases:

>100_bases
GAATTTTTTTCAGGACAGATTTTAATTTTCAATAAGCCACAAACTGGATTTTTCTTGCCGATCGGTTTAATTTTTTAAAA
CTGTTCAAGCGTTCTTTTTT

Downstream 100 bases:

>100_bases
AAATCTCTAAATCTTTAAGAGCCTTTCACATCTCCACTTGAATAGAACCTTTTGAAGTAGTAACACTCAACGATAAGAAT
ATAAGATTATGGTAAAATTT

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MIRLETRFASSFIQSSKLEPFLEKSESARLTLHSSQGQGKEYLGWLYLPKELKNSEIERMTQVAERLRNSSEVIVVIGIG
GSYLGSRAVLEATLPFFKKPSIGNPEIIFAGHHLESRYFSELIEYLEDKNFSINVISKSGTTTEPAIAFRLLWELLRKKY
GSSASSRVVATTDSSKGVLKKFADSEKLDTFTIPDNVGGRYSVLTPVGLFPLAVAGISISKFILGFQNILNDIHSITDPT
RNPATYYSALRNYFLSEGRYIEVLANFNPSLRYVSEWWKQLFGESEGKENKGIFPASMDFTTDLHSLGQYIQEGKRILFE
TVLSPSEVCSNLTLKPTQDNLDSLNFLSGNTLGYVNEQARLGTLLAHADGGVPCLELVFPDISPQSLGELMYFFEYSCAI
SGYSLGVNPFDQPGVEAYKKNMFALLNKPGFEQEGETLRKRISRN

Sequences:

>Translated_445_residues
MIRLETRFASSFIQSSKLEPFLEKSESARLTLHSSQGQGKEYLGWLYLPKELKNSEIERMTQVAERLRNSSEVIVVIGIG
GSYLGSRAVLEATLPFFKKPSIGNPEIIFAGHHLESRYFSELIEYLEDKNFSINVISKSGTTTEPAIAFRLLWELLRKKY
GSSASSRVVATTDSSKGVLKKFADSEKLDTFTIPDNVGGRYSVLTPVGLFPLAVAGISISKFILGFQNILNDIHSITDPT
RNPATYYSALRNYFLSEGRYIEVLANFNPSLRYVSEWWKQLFGESEGKENKGIFPASMDFTTDLHSLGQYIQEGKRILFE
TVLSPSEVCSNLTLKPTQDNLDSLNFLSGNTLGYVNEQARLGTLLAHADGGVPCLELVFPDISPQSLGELMYFFEYSCAI
SGYSLGVNPFDQPGVEAYKKNMFALLNKPGFEQEGETLRKRISRN
>Mature_445_residues
MIRLETRFASSFIQSSKLEPFLEKSESARLTLHSSQGQGKEYLGWLYLPKELKNSEIERMTQVAERLRNSSEVIVVIGIG
GSYLGSRAVLEATLPFFKKPSIGNPEIIFAGHHLESRYFSELIEYLEDKNFSINVISKSGTTTEPAIAFRLLWELLRKKY
GSSASSRVVATTDSSKGVLKKFADSEKLDTFTIPDNVGGRYSVLTPVGLFPLAVAGISISKFILGFQNILNDIHSITDPT
RNPATYYSALRNYFLSEGRYIEVLANFNPSLRYVSEWWKQLFGESEGKENKGIFPASMDFTTDLHSLGQYIQEGKRILFE
TVLSPSEVCSNLTLKPTQDNLDSLNFLSGNTLGYVNEQARLGTLLAHADGGVPCLELVFPDISPQSLGELMYFFEYSCAI
SGYSLGVNPFDQPGVEAYKKNMFALLNKPGFEQEGETLRKRISRN

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family

Homologues:

Organism=Saccharomyces cerevisiae, GI6319673, Length=398, Percent_Identity=24.3718592964824, Blast_Score=66, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): G6PI_LEPIC (Q72MT7)

Other databases:

- EMBL:   AE016823
- RefSeq:   YP_003014.1
- ProteinModelPortal:   Q72MT7
- SMR:   Q72MT7
- GeneID:   2771728
- GenomeReviews:   AE016823_GR
- KEGG:   lic:LIC13105
- HOGENOM:   HBG615843
- OMA:   MMQGAAD
- ProtClustDB:   PRK14097
- BioCyc:   LINT267671:LIC_13105-MONOMER
- GO:   GO:0005737
- GO:   GO:0006094
- GO:   GO:0006096
- HAMAP:   MF_00473
- InterPro:   IPR001672
- InterPro:   IPR018189
- PANTHER:   PTHR11469
- PRINTS:   PR00662

Pfam domain/function: PF00342 PGI

EC number: =5.3.1.9

Molecular weight: Translated: 49735; Mature: 49735

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1; PS00174 P_GLUCOSE_ISOMERASE_2; PS51463 P_GLUCOSE_ISOMERASE_3; PS50097 BTB

Important sites: ACT_SITE 284-284 ACT_SITE 305-305 ACT_SITE 419-419

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRLETRFASSFIQSSKLEPFLEKSESARLTLHSSQGQGKEYLGWLYLPKELKNSEIERM
CEEEHHHHHHHHHHHCCCCHHHHCCCCCEEEEECCCCCCCHHEEEEEECHHHCCHHHHHH
TQVAERLRNSSEVIVVIGIGGSYLGSRAVLEATLPFFKKPSIGNPEIIFAGHHLESRYFS
HHHHHHHCCCCCEEEEEECCCHHHCCHHHHHHHCCHHCCCCCCCCCEEEECCCHHHHHHH
ELIEYLEDKNFSINVISKSGTTTEPAIAFRLLWELLRKKYGSSASSRVVATTDSSKGVLK
HHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHH
KFADSEKLDTFTIPDNVGGRYSVLTPVGLFPLAVAGISISKFILGFQNILNDIHSITDPT
HHCCCCCCCEEECCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RNPATYYSALRNYFLSEGRYIEVLANFNPSLRYVSEWWKQLFGESEGKENKGIFPASMDF
CCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCH
TTDLHSLGQYIQEGKRILFETVLSPSEVCSNLTLKPTQDNLDSLNFLSGNTLGYVNEQAR
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCEECCCHHH
LGTLLAHADGGVPCLELVFPDISPQSLGELMYFFEYSCAISGYSLGVNPFDQPGVEAYKK
HHHHHEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
NMFALLNKPGFEQEGETLRKRISRN
HHHHHHCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MIRLETRFASSFIQSSKLEPFLEKSESARLTLHSSQGQGKEYLGWLYLPKELKNSEIERM
CEEEHHHHHHHHHHHCCCCHHHHCCCCCEEEEECCCCCCCHHEEEEEECHHHCCHHHHHH
TQVAERLRNSSEVIVVIGIGGSYLGSRAVLEATLPFFKKPSIGNPEIIFAGHHLESRYFS
HHHHHHHCCCCCEEEEEECCCHHHCCHHHHHHHCCHHCCCCCCCCCEEEECCCHHHHHHH
ELIEYLEDKNFSINVISKSGTTTEPAIAFRLLWELLRKKYGSSASSRVVATTDSSKGVLK
HHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHH
KFADSEKLDTFTIPDNVGGRYSVLTPVGLFPLAVAGISISKFILGFQNILNDIHSITDPT
HHCCCCCCCEEECCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RNPATYYSALRNYFLSEGRYIEVLANFNPSLRYVSEWWKQLFGESEGKENKGIFPASMDF
CCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCH
TTDLHSLGQYIQEGKRILFETVLSPSEVCSNLTLKPTQDNLDSLNFLSGNTLGYVNEQAR
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCEECCCHHH
LGTLLAHADGGVPCLELVFPDISPQSLGELMYFFEYSCAISGYSLGVNPFDQPGVEAYKK
HHHHHEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
NMFALLNKPGFEQEGETLRKRISRN
HHHHHHCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA