Click here to switch to the map view.

The map label for this gene is coaE

Identifier: 45658911

GI number: 45658911

Start: 3770360

End: 3770950

Strand: Reverse

Name: coaE

Synonym: LIC13085

Alternate gene names: 45658911

Gene position: 3770950-3770360 (Counterclockwise)

Preceding gene: 45658916

Following gene: 45658910

Centisome position: 88.16

GC content: 34.35

Gene sequence:

>591_bases
TTGATTGGGATTACTGGAATGATCGGAGGAGGTAAAAGTACCGCGACTAAAATTTTGGAAGAAATGGGATGTTTTGGAAT
CAATGCAGATCGTTTGGCCAAACGTTATACAGAACCAGATTCTCCTATTTTAATCGAACTTGTGGAACTTTTAGGAAGTG
AGATTTTAGATGAGCAAGGAAAACCGGATAGGAAAAAAATTTCGGAAATTGTTTTTAATAATCCGAAAAAATTGTCAAGA
CTGAATCAATTGATTCATCCTTTGGTTAGAAAAGATTTTCAAAAAATTTTAGAAACGACTGCAAAAGGAAAAATGGTAAT
TTGGGAAGTTCCACTTTTGTTTGAAACTGACGCTTATACTCTCTGCGACGCAACCGTAACCGTGGATTCCGATCCTGAAG
AATCAATTTTAAGAACAATTTCAAGGGACAAAGTGAAAAAAGAAGACGTTTTAGCTAGAATCAAAAACCAACTTCCTCTT
ACGGAAAAACTAAAAAGAGCCGATTATATACTTAGAAACAGAGGGAATATAGATTCTCTGAGAGAAGAATGTAAAAGTTT
ATACTCCACTTTATTGGGAAAAATGTTATGA

Upstream 100 bases:

>100_bases
AATAAAGCTTTCTAAACAATCTATCTTTTTTGCTTGTACTTTTGTCCAGGCGCTCTATCTTCAACGTATGCAGAATTCCG
ATTCTGGTAAAAAAACCTTT

Downstream 100 bases:

>100_bases
AAGAAAAAATTTTTTATGTGATCAATTTGGATAATAAGAGAATTCTAATTTTATCCACGTTCTTAATCGGATTGCTTTTC
TCATTCTTTTTATTAGGAGT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MIGITGMIGGGKSTATKILEEMGCFGINADRLAKRYTEPDSPILIELVELLGSEILDEQGKPDRKKISEIVFNNPKKLSR
LNQLIHPLVRKDFQKILETTAKGKMVIWEVPLLFETDAYTLCDATVTVDSDPEESILRTISRDKVKKEDVLARIKNQLPL
TEKLKRADYILRNRGNIDSLREECKSLYSTLLGKML

Sequences:

>Translated_196_residues
MIGITGMIGGGKSTATKILEEMGCFGINADRLAKRYTEPDSPILIELVELLGSEILDEQGKPDRKKISEIVFNNPKKLSR
LNQLIHPLVRKDFQKILETTAKGKMVIWEVPLLFETDAYTLCDATVTVDSDPEESILRTISRDKVKKEDVLARIKNQLPL
TEKLKRADYILRNRGNIDSLREECKSLYSTLLGKML
>Mature_196_residues
MIGITGMIGGGKSTATKILEEMGCFGINADRLAKRYTEPDSPILIELVELLGSEILDEQGKPDRKKISEIVFNNPKKLSR
LNQLIHPLVRKDFQKILETTAKGKMVIWEVPLLFETDAYTLCDATVTVDSDPEESILRTISRDKVKKEDVLARIKNQLPL
TEKLKRADYILRNRGNIDSLREECKSLYSTLLGKML

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=194, Percent_Identity=32.9896907216495, Blast_Score=120, Evalue=8e-28,
Organism=Homo sapiens, GI191252795, Length=194, Percent_Identity=32.9896907216495, Blast_Score=120, Evalue=8e-28,
Organism=Homo sapiens, GI110227607, Length=173, Percent_Identity=27.7456647398844, Blast_Score=78, Evalue=5e-15,
Organism=Homo sapiens, GI110227605, Length=173, Percent_Identity=27.7456647398844, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI110227603, Length=173, Percent_Identity=27.7456647398844, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI110227601, Length=173, Percent_Identity=27.7456647398844, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI205277394, Length=173, Percent_Identity=27.7456647398844, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI1786292, Length=192, Percent_Identity=30.7291666666667, Blast_Score=109, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17554944, Length=195, Percent_Identity=32.3076923076923, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6320402, Length=194, Percent_Identity=31.4432989690722, Blast_Score=92, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24644728, Length=194, Percent_Identity=26.8041237113402, Blast_Score=101, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24658602, Length=195, Percent_Identity=25.1282051282051, Blast_Score=84, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22162; Mature: 22162

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGITGMIGGGKSTATKILEEMGCFGINADRLAKRYTEPDSPILIELVELLGSEILDEQG
CCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
KPDRKKISEIVFNNPKKLSRLNQLIHPLVRKDFQKILETTAKGKMVIWEVPLLFETDAYT
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEECCCHH
LCDATVTVDSDPEESILRTISRDKVKKEDVLARIKNQLPLTEKLKRADYILRNRGNIDSL
HCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHH
REECKSLYSTLLGKML
HHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIGITGMIGGGKSTATKILEEMGCFGINADRLAKRYTEPDSPILIELVELLGSEILDEQG
CCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
KPDRKKISEIVFNNPKKLSRLNQLIHPLVRKDFQKILETTAKGKMVIWEVPLLFETDAYT
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEECCCHH
LCDATVTVDSDPEESILRTISRDKVKKEDVLARIKNQLPLTEKLKRADYILRNRGNIDSL
HCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHH
REECKSLYSTLLGKML
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA