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The map label for this gene is lipA [H]

Identifier: 45658815

GI number: 45658815

Start: 3628817

End: 3629737

Strand: Direct

Name: lipA [H]

Synonym: LIC12988

Alternate gene names: 45658815

Gene position: 3628817-3629737 (Clockwise)

Preceding gene: 45658808

Following gene: 45658821

Centisome position: 84.84

GC content: 41.26

Gene sequence:

>921_bases
ATGAAAAAAATGAATTTGAAAATTTTATTAACGTTAGTGTTTCTAATAACGAACGTTACATATGCGTCTGGAGGAGGAAC
CTCTAGTAAACCTCTTTCTGGAAGTTATCCGATCGTACTAGCCCACGGATTGTTTGGTTGGGGAAACGGCTCTACCGTTG
TTGATTATTGGGGTGGAAATGCCGCCTATCTTAGAAATCAAGGTGCGTATGTTCTAACTCCTTCCGTCACTGCGTTAAAT
TCAAGTTCCAGCAGAGCCTCCCAATTAAAAACGTCTATTCTAGCGGCTATGGCTGCAAACAATTATACCGGCAAGGTGCA
TATCATAGGGCATTCACAGGGTGGATTGGATGCGCGTTATATGGTTTCCAACCTTTCTATGAGTACTAAGGTTGCCACCT
TAACGACGTTAAATACTCCTCATCAAGGAAGTCCTATCGCAAATATCGTAGCAGCGGTTATTCCTAATTGGGCTTTACCT
TACGTTTCAACGGTTTTAAATACTATAATCGGTTTTGTTTATGGAGATTCCAGCCAGAACGCTATCTCAGCTTTAAAACT
TCTTACCACAGACGGACTAAAAACGTTCAACTCTGTAACGCCTAACGTGTATGGTGTAAAATATTTTTCGTATGGATCAA
CGATCAGCGTTCCAGATCTAATTCAACATCCAGCGATGGGAATCTTACATCCGATCTGCGCAATCGGAGCTCCTTTTTAC
GGGATGAGTATCGCAAATGACGGTGTAGTTCCAGATTCTTCTCAAAGGTGGGGAACTTGGAAAGGAGGACCTTCAATACC
AATTTTGACCACGGGAATAGATCATTTAGAAGCAACCAACGCTCTCTATCTAGGACAACTCTGGTACGATACAAATGCTT
ATTTCTTAAAGATGGCGAATAACGCAAAATCTAATCAATAA

Upstream 100 bases:

>100_bases
TTTACTCAAGACTTCTAATTTCAATTTTTTGCTTGATTGATTTTTCTAATAAAGTATGTTCCAACGCGTTTCCAATTGAA
AATTAAATTAGGTAAAAAAT

Downstream 100 bases:

>100_bases
AATAGATTGAATCAAGATCTCCCTAAAATTATACCCGATTTTGGGGAGTTTTTTGCGATCAGTTCAATATCATCTAATGT
TAATTAGGCGTGAAAGTTTG

Product: lipase

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MKKMNLKILLTLVFLITNVTYASGGGTSSKPLSGSYPIVLAHGLFGWGNGSTVVDYWGGNAAYLRNQGAYVLTPSVTALN
SSSSRASQLKTSILAAMAANNYTGKVHIIGHSQGGLDARYMVSNLSMSTKVATLTTLNTPHQGSPIANIVAAVIPNWALP
YVSTVLNTIIGFVYGDSSQNAISALKLLTTDGLKTFNSVTPNVYGVKYFSYGSTISVPDLIQHPAMGILHPICAIGAPFY
GMSIANDGVVPDSSQRWGTWKGGPSIPILTTGIDHLEATNALYLGQLWYDTNAYFLKMANNAKSNQ

Sequences:

>Translated_306_residues
MKKMNLKILLTLVFLITNVTYASGGGTSSKPLSGSYPIVLAHGLFGWGNGSTVVDYWGGNAAYLRNQGAYVLTPSVTALN
SSSSRASQLKTSILAAMAANNYTGKVHIIGHSQGGLDARYMVSNLSMSTKVATLTTLNTPHQGSPIANIVAAVIPNWALP
YVSTVLNTIIGFVYGDSSQNAISALKLLTTDGLKTFNSVTPNVYGVKYFSYGSTISVPDLIQHPAMGILHPICAIGAPFY
GMSIANDGVVPDSSQRWGTWKGGPSIPILTTGIDHLEATNALYLGQLWYDTNAYFLKMANNAKSNQ
>Mature_306_residues
MKKMNLKILLTLVFLITNVTYASGGGTSSKPLSGSYPIVLAHGLFGWGNGSTVVDYWGGNAAYLRNQGAYVLTPSVTALN
SSSSRASQLKTSILAAMAANNYTGKVHIIGHSQGGLDARYMVSNLSMSTKVATLTTLNTPHQGSPIANIVAAVIPNWALP
YVSTVLNTIIGFVYGDSSQNAISALKLLTTDGLKTFNSVTPNVYGVKYFSYGSTISVPDLIQHPAMGILHPICAIGAPFY
GMSIANDGVVPDSSQRWGTWKGGPSIPILTTGIDHLEATNALYLGQLWYDTNAYFLKMANNAKSNQ

Specific function: Catalyzes the hydrolysis of triglycerides [H]

COG id: COG1075

COG function: function code R; Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Lipase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320263, Length=248, Percent_Identity=29.8387096774194, Blast_Score=96, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 32461; Mature: 32461

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKMNLKILLTLVFLITNVTYASGGGTSSKPLSGSYPIVLAHGLFGWGNGSTVVDYWGGN
CCCCHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCEEEEECCEEECCCCEEEEECCCC
AAYLRNQGAYVLTPSVTALNSSSSRASQLKTSILAAMAANNYTGKVHIIGHSQGGLDARY
EEEEECCCCEEECCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHH
MVSNLSMSTKVATLTTLNTPHQGSPIANIVAAVIPNWALPYVSTVLNTIIGFVYGDSSQN
HHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCCCH
AISALKLLTTDGLKTFNSVTPNVYGVKYFSYGSTISVPDLIQHPAMGILHPICAIGAPFY
HHHHHHHHHHCCHHHHHCCCCCEEEEEEEECCCCCCCHHHHHCCHHHHHHHHHHHCCCCC
GMSIANDGVVPDSSQRWGTWKGGPSIPILTTGIDHLEATNALYLGQLWYDTNAYFLKMAN
CEEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCHHHHCCEEEEEEEEECCCEEEEEEEC
NAKSNQ
CCCCCC
>Mature Secondary Structure
MKKMNLKILLTLVFLITNVTYASGGGTSSKPLSGSYPIVLAHGLFGWGNGSTVVDYWGGN
CCCCHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCEEEEECCEEECCCCEEEEECCCC
AAYLRNQGAYVLTPSVTALNSSSSRASQLKTSILAAMAANNYTGKVHIIGHSQGGLDARY
EEEEECCCCEEECCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHH
MVSNLSMSTKVATLTTLNTPHQGSPIANIVAAVIPNWALPYVSTVLNTIIGFVYGDSSQN
HHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCCCH
AISALKLLTTDGLKTFNSVTPNVYGVKYFSYGSTISVPDLIQHPAMGILHPICAIGAPFY
HHHHHHHHHHCCHHHHHCCCCCEEEEEEEECCCCCCCHHHHHCCHHHHHHHHHHHCCCCC
GMSIANDGVVPDSSQRWGTWKGGPSIPILTTGIDHLEATNALYLGQLWYDTNAYFLKMAN
CEEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCHHHHCCEEEEEEEEECCCEEEEEEEC
NAKSNQ
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]