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The map label for this gene is mcpA

Identifier: 45658750

GI number: 45658750

Start: 3545035

End: 3547113

Strand: Direct

Name: mcpA

Synonym: LIC12921

Alternate gene names: 45658750

Gene position: 3545035-3547113 (Clockwise)

Preceding gene: 45658749

Following gene: 45658751

Centisome position: 82.88

GC content: 38.34

Gene sequence:

>2079_bases
ATGAGCATTCGTTTTCGCATTTCTCTCTATCTTTCCATCGTGTTATTCATAGGTTTCGGTATTCTTGCAAGTATCAGTTG
TTACACCGCATATAAAAAGTTAGAACAAGAAGTTGTCAATAGTTCAGAAATTACAGCCGAACGTTGGACCTATGAAGTGA
AAGATTATTTAGACACTGGTATGGGTATCATACGAGGTTTTCGGTTTCCTCTTCTCTTTAGTGCCCCTCCCCGCAATCAA
ATCATTGCTGCTTTAAGAGAAATCTTAAAAGTCAATGATCATTACTTTGGTGCCAGACTCGCCTACGAACCAAATTCTTT
GGACGGAAACGACTTAGAATTTCAAAATACTCTAGGACATGATTCCACAGGCAGATTTATTCCGTATCTTCATCGTGGTC
AAACAAAGGAAGAAATCGTTCTCGAAGCCGCTAAATACTACGATTCTTTAGGTCCGGAAGGAGATTGGTACCAAGTTCCT
AAAAAAACAAAATCTCACTACGCAACGGATCCGTACTATTATGAAATCAAAGGGAAAGTAAAAATTCTAATGATGTCTCT
TATGGTTCCGCTTTATGTAAACGATCAGTTTTACGGTGTTGCCGGTTTAGACTATCAATTGGAAGAACTTCAACAACGAA
TCGGCGTTAAAAAACCGTTTCAAGATCTTGGTTATCTAACTCTGATTTCTCCTAAAGGAATTTATGCAGTAAATGGTTTT
GATTCAAATCGGGTCGGTGAAAAAATTTCAGATGCAAAAGAACTAGAATATTACCTTAGTAAAAGTCAGGAAGGCGAAAA
ATTCACTACTGATTCCGACGGATACACTCATTATTACTTTCCGTTTCATATTGGTAAAGACAAACGCTATTGGGTAATGC
AAGTAAGTATTCCAAATTCTATCTATAAAGAAGCAATTCTTTCTATTCTTTTCAAAGCTTTTACGTACACCTTAGCGGTA
TTAATCGCCGTCATTCTTTGCCTAAACGTTATATTCCAAAAATTGATTACCGCCGGTCTTCTCAAAGCAGTTAGTTTTTC
CGAAGAAATCGCAGACGGAAATTTAATCGCTCAAAGTTCTCACGATAAAAAAGACGAAATCGGAACTCTTCTCAGTTCCA
TGAATAAAATGAGGGAAAATCTTCTCAAAGTTCTGAGAGAAATAGGGGGTTCAGCAAACACTCTCAGAGATACTTCAGAA
AAAATGGCCGATTCATCTAGAAACTTTTCTGACGTCGCTCAAACTCAAGCTTCTGCTGCTGAAGAATCTTCTGCTGCTGT
CGAAGAACTCGCCGCTTCCGCACAAAACGTGGGAAAGTCTATGGAAAAGGCTGTATTGAGTATGAAAGAAATCGATGGTA
ACGTCATTCGTCTAAAAGAACAAATCGTAAATATCAATAGAGAAATGCAAGATCTAGTTGAGCTCGCAGCCCTTTCAAAA
GAACAAGGTGTCACTGGAGAAAATGCTATGATCGCTTCTACAAGCGCTATGGCGGCTATCGGAGACAGCGCTTCCAGAAT
CACTGAAATCCTTTCTATAATTACTGAAATTTCGGAAAGAACAAATCTACTTGCTCTCAATGCCGCTATCGAAGCCGCTA
GAGCTGGTGAAGCCGGAAAAGGATTTGCTGTTGTCGCAGAAGAAATTGGAAAACTCGCTTCTCAAACTTCTACAAGTGTT
CAAGAAATTGGGTCTCTGGTGAATTCCACTAATACCGCCGTTTTAAATGGAAACACTAAAGTTGCAGAAGCTTTTAACAT
TCTAAAAAAACTTAGAGAACAAGTAGAAGAATTCGATCGTTATGCTAAGAACGTTCTTACTTCCGTTAAAACTCAGGAAG
AAAATACTAAAGAAATCGCACAAAGTGCTAATGAACTTATGACCTTCAGTTTACAAATTGAAGAAGCTGTTCTAGAACAA
AGACGTGCCACGGATGAAATTACAAAAACGATCATGAGCATTTCTGACGGTACTCAAGAAATCGCTTCAGGTGCAGAAGA
TCTTACTTCATTCTCCGGAAATATGCACGGACAAGCTCAAAATCTAGGAAAATTGATCGGTAAGTTTAAAATCAACTAA

Upstream 100 bases:

>100_bases
TTTTTTTATAAATTAGGAATATTTTGCTCGAGCAATTCGTCCTACCCTCTATTAATTATCCTTTTGGTTACCTTAGAATC
AGAACGAGCCGGGGGGCGCA

Downstream 100 bases:

>100_bases
GATTGGTAGTTGTGGGAACTAACACAAATTCGAGATTTCACTGTAAAATTCAGAAATGTGGGAACTAACACAAACTAAAA
CAACCCGAAAAACGGTTGAA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 692; Mature: 691

Protein sequence:

>692_residues
MSIRFRISLYLSIVLFIGFGILASISCYTAYKKLEQEVVNSSEITAERWTYEVKDYLDTGMGIIRGFRFPLLFSAPPRNQ
IIAALREILKVNDHYFGARLAYEPNSLDGNDLEFQNTLGHDSTGRFIPYLHRGQTKEEIVLEAAKYYDSLGPEGDWYQVP
KKTKSHYATDPYYYEIKGKVKILMMSLMVPLYVNDQFYGVAGLDYQLEELQQRIGVKKPFQDLGYLTLISPKGIYAVNGF
DSNRVGEKISDAKELEYYLSKSQEGEKFTTDSDGYTHYYFPFHIGKDKRYWVMQVSIPNSIYKEAILSILFKAFTYTLAV
LIAVILCLNVIFQKLITAGLLKAVSFSEEIADGNLIAQSSHDKKDEIGTLLSSMNKMRENLLKVLREIGGSANTLRDTSE
KMADSSRNFSDVAQTQASAAEESSAAVEELAASAQNVGKSMEKAVLSMKEIDGNVIRLKEQIVNINREMQDLVELAALSK
EQGVTGENAMIASTSAMAAIGDSASRITEILSIITEISERTNLLALNAAIEAARAGEAGKGFAVVAEEIGKLASQTSTSV
QEIGSLVNSTNTAVLNGNTKVAEAFNILKKLREQVEEFDRYAKNVLTSVKTQEENTKEIAQSANELMTFSLQIEEAVLEQ
RRATDEITKTIMSISDGTQEIASGAEDLTSFSGNMHGQAQNLGKLIGKFKIN

Sequences:

>Translated_692_residues
MSIRFRISLYLSIVLFIGFGILASISCYTAYKKLEQEVVNSSEITAERWTYEVKDYLDTGMGIIRGFRFPLLFSAPPRNQ
IIAALREILKVNDHYFGARLAYEPNSLDGNDLEFQNTLGHDSTGRFIPYLHRGQTKEEIVLEAAKYYDSLGPEGDWYQVP
KKTKSHYATDPYYYEIKGKVKILMMSLMVPLYVNDQFYGVAGLDYQLEELQQRIGVKKPFQDLGYLTLISPKGIYAVNGF
DSNRVGEKISDAKELEYYLSKSQEGEKFTTDSDGYTHYYFPFHIGKDKRYWVMQVSIPNSIYKEAILSILFKAFTYTLAV
LIAVILCLNVIFQKLITAGLLKAVSFSEEIADGNLIAQSSHDKKDEIGTLLSSMNKMRENLLKVLREIGGSANTLRDTSE
KMADSSRNFSDVAQTQASAAEESSAAVEELAASAQNVGKSMEKAVLSMKEIDGNVIRLKEQIVNINREMQDLVELAALSK
EQGVTGENAMIASTSAMAAIGDSASRITEILSIITEISERTNLLALNAAIEAARAGEAGKGFAVVAEEIGKLASQTSTSV
QEIGSLVNSTNTAVLNGNTKVAEAFNILKKLREQVEEFDRYAKNVLTSVKTQEENTKEIAQSANELMTFSLQIEEAVLEQ
RRATDEITKTIMSISDGTQEIASGAEDLTSFSGNMHGQAQNLGKLIGKFKIN
>Mature_691_residues
SIRFRISLYLSIVLFIGFGILASISCYTAYKKLEQEVVNSSEITAERWTYEVKDYLDTGMGIIRGFRFPLLFSAPPRNQI
IAALREILKVNDHYFGARLAYEPNSLDGNDLEFQNTLGHDSTGRFIPYLHRGQTKEEIVLEAAKYYDSLGPEGDWYQVPK
KTKSHYATDPYYYEIKGKVKILMMSLMVPLYVNDQFYGVAGLDYQLEELQQRIGVKKPFQDLGYLTLISPKGIYAVNGFD
SNRVGEKISDAKELEYYLSKSQEGEKFTTDSDGYTHYYFPFHIGKDKRYWVMQVSIPNSIYKEAILSILFKAFTYTLAVL
IAVILCLNVIFQKLITAGLLKAVSFSEEIADGNLIAQSSHDKKDEIGTLLSSMNKMRENLLKVLREIGGSANTLRDTSEK
MADSSRNFSDVAQTQASAAEESSAAVEELAASAQNVGKSMEKAVLSMKEIDGNVIRLKEQIVNINREMQDLVELAALSKE
QGVTGENAMIASTSAMAAIGDSASRITEILSIITEISERTNLLALNAAIEAARAGEAGKGFAVVAEEIGKLASQTSTSVQ
EIGSLVNSTNTAVLNGNTKVAEAFNILKKLREQVEEFDRYAKNVLTSVKTQEENTKEIAQSANELMTFSLQIEEAVLEQR
RATDEITKTIMSISDGTQEIASGAEDLTSFSGNMHGQAQNLGKLIGKFKIN

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=312, Percent_Identity=27.8846153846154, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1788195, Length=315, Percent_Identity=27.6190476190476, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1787690, Length=391, Percent_Identity=26.0869565217391, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1789453, Length=352, Percent_Identity=23.2954545454545, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788194, Length=339, Percent_Identity=24.7787610619469, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 76738; Mature: 76607

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIRFRISLYLSIVLFIGFGILASISCYTAYKKLEQEVVNSSEITAERWTYEVKDYLDTG
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
MGIIRGFRFPLLFSAPPRNQIIAALREILKVNDHYFGARLAYEPNSLDGNDLEFQNTLGH
HHHHHHCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCHHHHCCC
DSTGRFIPYLHRGQTKEEIVLEAAKYYDSLGPEGDWYQVPKKTKSHYATDPYYYEIKGKV
CCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCCCEECCCHHHCCCCCCCEEEEECCHH
KILMMSLMVPLYVNDQFYGVAGLDYQLEELQQRIGVKKPFQDLGYLTLISPKGIYAVNGF
HHHHHHHHHHHEECCCEEEECCCCHHHHHHHHHCCCCCCHHHCCEEEEECCCCEEEECCC
DSNRVGEKISDAKELEYYLSKSQEGEKFTTDSDGYTHYYFPFHIGKDKRYWVMQVSIPNS
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCCCEEEEEEEECCHH
IYKEAILSILFKAFTYTLAVLIAVILCLNVIFQKLITAGLLKAVSFSEEIADGNLIAQSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
HDKKDEIGTLLSSMNKMRENLLKVLREIGGSANTLRDTSEKMADSSRNFSDVAQTQASAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
EESSAAVEELAASAQNVGKSMEKAVLSMKEIDGNVIRLKEQIVNINREMQDLVELAALSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQGVTGENAMIASTSAMAAIGDSASRITEILSIITEISERTNLLALNAAIEAARAGEAGK
HCCCCCCCCEEECHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCC
GFAVVAEEIGKLASQTSTSVQEIGSLVNSTNTAVLNGNTKVAEAFNILKKLREQVEEFDR
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHH
YAKNVLTSVKTQEENTKEIAQSANELMTFSLQIEEAVLEQRRATDEITKTIMSISDGTQE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
IASGAEDLTSFSGNMHGQAQNLGKLIGKFKIN
HHCCHHHHHHHCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SIRFRISLYLSIVLFIGFGILASISCYTAYKKLEQEVVNSSEITAERWTYEVKDYLDTG
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
MGIIRGFRFPLLFSAPPRNQIIAALREILKVNDHYFGARLAYEPNSLDGNDLEFQNTLGH
HHHHHHCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCHHHHCCC
DSTGRFIPYLHRGQTKEEIVLEAAKYYDSLGPEGDWYQVPKKTKSHYATDPYYYEIKGKV
CCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCCCEECCCHHHCCCCCCCEEEEECCHH
KILMMSLMVPLYVNDQFYGVAGLDYQLEELQQRIGVKKPFQDLGYLTLISPKGIYAVNGF
HHHHHHHHHHHEECCCEEEECCCCHHHHHHHHHCCCCCCHHHCCEEEEECCCCEEEECCC
DSNRVGEKISDAKELEYYLSKSQEGEKFTTDSDGYTHYYFPFHIGKDKRYWVMQVSIPNS
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEECCCCEEEEEEEECCHH
IYKEAILSILFKAFTYTLAVLIAVILCLNVIFQKLITAGLLKAVSFSEEIADGNLIAQSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
HDKKDEIGTLLSSMNKMRENLLKVLREIGGSANTLRDTSEKMADSSRNFSDVAQTQASAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
EESSAAVEELAASAQNVGKSMEKAVLSMKEIDGNVIRLKEQIVNINREMQDLVELAALSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQGVTGENAMIASTSAMAAIGDSASRITEILSIITEISERTNLLALNAAIEAARAGEAGK
HCCCCCCCCEEECHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCC
GFAVVAEEIGKLASQTSTSVQEIGSLVNSTNTAVLNGNTKVAEAFNILKKLREQVEEFDR
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHH
YAKNVLTSVKTQEENTKEIAQSANELMTFSLQIEEAVLEQRRATDEITKTIMSISDGTQE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
IASGAEDLTSFSGNMHGQAQNLGKLIGKFKIN
HHCCHHHHHHHCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]