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The map label for this gene is ruvB

Identifier: 45658642

GI number: 45658642

Start: 3416206

End: 3417231

Strand: Reverse

Name: ruvB

Synonym: LIC12811

Alternate gene names: 45658642

Gene position: 3417231-3416206 (Counterclockwise)

Preceding gene: 45658643

Following gene: 45658641

Centisome position: 79.89

GC content: 39.96

Gene sequence:

>1026_bases
TTGGCAAAATCCCATACTCTGAATCCTGAAGAAGAATTTGAAGAAGAGTCGGGCCTTCGCCCTTCTCTTCTTTCCGAATT
TATAGGTCAAAAAGAAGTCCTCAATAATCTTACCGTTTACGTTCAAGCAGCTAAAAATCGCAAACGTGCACTGGATCATG
TTTTAATTTCTGGTCCTCCCGGTCTTGGTAAAACTACACTTGCAGGAATCATTTCCAATGAACTTGGGACAAGGCTTACT
ATTACTTCGGCTCCCGTAATTACCAAAGGAGCGGATCTTGCCCGTCTTCTTACTAGCATGGGAGAAAATGAAATTTTATT
CATAGACGAGATTCATACTCTTCCTAAAAAACTAGAAGAAATTCTATATCCTGCGATGGAAAACTATATGATCGATCTGG
TCATCGGAGAAGGTGTGACCGCTCAGATGGTTCAGATTCCTCTAAAACCTTTTACTTTGGTGGGAGCTACGACTAGAAGC
GGTTTGATCAGCGAACCGCTGAAAAGTCGTTTCGGAATTCAACTCAGATTAGATTATTACAACGATGAAGAAATGAAACA
AATCGTTTTACGTTCTTCTAAAATTCTAGGAGTTTTGATTGAAGACGACGCTGCTTTGGAAATCGGAAAACGTTCCCGTA
AAACTCCTAGAATTGCAAATCATCTTTTAAAAAGAATCCGTGATTTCAGCGAAGTAGAAGGAAATCTTTCTGTAAAAAAG
AATCTTTGTTTGAAGGCTTTTGAAAAGATGGGGATTGACGATCTGGGTCTGGATGGTATGGATAGACAGATTCTAGATTG
TATGATCGATCGTTATAAAGGTGGTCCGGTTGGACTCAAAGCAATTGCGGTTGTGGTAGGCGAGGAAGAAAAAACAATCG
AAGATACTTATGAATCTTTTATGGTTCGAATTGGGCTTATCAATCGAACTCCCGCAGGTAGAGTTGCGACTGAAAAGGCT
TATCGCCAATTGAAAAGAATGGAAGATTTTTCCGTACATCATGGACAAGACCCGACTTTATTCTGA

Upstream 100 bases:

>100_bases
AGTCAAAAAAAATAAGGTAGGGGATAGAATTACGGTTACCGTTGTACGTCAAGGGAACATTTCCAGAATCTCTATCCAAC
TTAAGGAAAGACCGAACTGA

Downstream 100 bases:

>100_bases
ATATTCTGGAATTCCTGAAGACGATCAGAGACTGATCTACGCTTCTTTTCTAGTTCTTGCTCTCGCGTCTTTTTTTACCG
CACATTTACTTACAAGAAAC

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MAKSHTLNPEEEFEEESGLRPSLLSEFIGQKEVLNNLTVYVQAAKNRKRALDHVLISGPPGLGKTTLAGIISNELGTRLT
ITSAPVITKGADLARLLTSMGENEILFIDEIHTLPKKLEEILYPAMENYMIDLVIGEGVTAQMVQIPLKPFTLVGATTRS
GLISEPLKSRFGIQLRLDYYNDEEMKQIVLRSSKILGVLIEDDAALEIGKRSRKTPRIANHLLKRIRDFSEVEGNLSVKK
NLCLKAFEKMGIDDLGLDGMDRQILDCMIDRYKGGPVGLKAIAVVVGEEEKTIEDTYESFMVRIGLINRTPAGRVATEKA
YRQLKRMEDFSVHHGQDPTLF

Sequences:

>Translated_341_residues
MAKSHTLNPEEEFEEESGLRPSLLSEFIGQKEVLNNLTVYVQAAKNRKRALDHVLISGPPGLGKTTLAGIISNELGTRLT
ITSAPVITKGADLARLLTSMGENEILFIDEIHTLPKKLEEILYPAMENYMIDLVIGEGVTAQMVQIPLKPFTLVGATTRS
GLISEPLKSRFGIQLRLDYYNDEEMKQIVLRSSKILGVLIEDDAALEIGKRSRKTPRIANHLLKRIRDFSEVEGNLSVKK
NLCLKAFEKMGIDDLGLDGMDRQILDCMIDRYKGGPVGLKAIAVVVGEEEKTIEDTYESFMVRIGLINRTPAGRVATEKA
YRQLKRMEDFSVHHGQDPTLF
>Mature_340_residues
AKSHTLNPEEEFEEESGLRPSLLSEFIGQKEVLNNLTVYVQAAKNRKRALDHVLISGPPGLGKTTLAGIISNELGTRLTI
TSAPVITKGADLARLLTSMGENEILFIDEIHTLPKKLEEILYPAMENYMIDLVIGEGVTAQMVQIPLKPFTLVGATTRSG
LISEPLKSRFGIQLRLDYYNDEEMKQIVLRSSKILGVLIEDDAALEIGKRSRKTPRIANHLLKRIRDFSEVEGNLSVKKN
LCLKAFEKMGIDDLGLDGMDRQILDCMIDRYKGGPVGLKAIAVVVGEEEKTIEDTYESFMVRIGLINRTPAGRVATEKAY
RQLKRMEDFSVHHGQDPTLF

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=309, Percent_Identity=47.8964401294498, Blast_Score=327, Evalue=5e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 38036; Mature: 37905

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSHTLNPEEEFEEESGLRPSLLSEFIGQKEVLNNLTVYVQAAKNRKRALDHVLISGPP
CCCCCCCCCHHHHHHHCCCCHHHHHHHHCHHHHHCCCEEEEEEHHHHHHHHHEEEEECCC
GLGKTTLAGIISNELGTRLTITSAPVITKGADLARLLTSMGENEILFIDEIHTLPKKLEE
CCCHHHHHHHHHHCCCCEEEEECCCCEECCHHHHHHHHHCCCCCEEEHHHHHHHHHHHHH
ILYPAMENYMIDLVIGEGVTAQMVQIPLKPFTLVGATTRSGLISEPLKSRFGIQLRLDYY
HHHHHHHCEEEEEEECCCCCCHHHEECCCCEEEEECCCCCCHHHHHHHHHCCEEEEEECC
NDEEMKQIVLRSSKILGVLIEDDAALEIGKRSRKTPRIANHLLKRIRDFSEVEGNLSVKK
CHHHHHHHHHHCCCEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
NLCLKAFEKMGIDDLGLDGMDRQILDCMIDRYKGGPVGLKAIAVVVGEEEKTIEDTYESF
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHH
MVRIGLINRTPAGRVATEKAYRQLKRMEDFSVHHGQDPTLF
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
AKSHTLNPEEEFEEESGLRPSLLSEFIGQKEVLNNLTVYVQAAKNRKRALDHVLISGPP
CCCCCCCCHHHHHHHCCCCHHHHHHHHCHHHHHCCCEEEEEEHHHHHHHHHEEEEECCC
GLGKTTLAGIISNELGTRLTITSAPVITKGADLARLLTSMGENEILFIDEIHTLPKKLEE
CCCHHHHHHHHHHCCCCEEEEECCCCEECCHHHHHHHHHCCCCCEEEHHHHHHHHHHHHH
ILYPAMENYMIDLVIGEGVTAQMVQIPLKPFTLVGATTRSGLISEPLKSRFGIQLRLDYY
HHHHHHHCEEEEEEECCCCCCHHHEECCCCEEEEECCCCCCHHHHHHHHHCCEEEEEECC
NDEEMKQIVLRSSKILGVLIEDDAALEIGKRSRKTPRIANHLLKRIRDFSEVEGNLSVKK
CHHHHHHHHHHCCCEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
NLCLKAFEKMGIDDLGLDGMDRQILDCMIDRYKGGPVGLKAIAVVVGEEEKTIEDTYESF
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHH
MVRIGLINRTPAGRVATEKAYRQLKRMEDFSVHHGQDPTLF
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA