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The map label for this gene is nlpD [H]

Identifier: 45658459

GI number: 45658459

Start: 3172732

End: 3173850

Strand: Direct

Name: nlpD [H]

Synonym: LIC12622

Alternate gene names: 45658459

Gene position: 3172732-3173850 (Clockwise)

Preceding gene: 45658458

Following gene: 45658460

Centisome position: 74.18

GC content: 39.14

Gene sequence:

>1119_bases
ATGATCTTCAAAAAGCCCAGACAACTGACCGCAGGAAAAGAAATCCTTCGGACGGAAAGTTTCACCCTGATTTATCTGGG
CGCGTTTCATTTTCATTATTCTTTTTATTTTAGAGGAAATCTCTATCACGGAAACTTAGATTTTCGTAGAAGAAAATTCA
GACTCATTCCTATCTTTGCATCCGTAGTTATTTTTCTTGCGATCTTGGGATTTGGAATGAATCCGAGTAACGCAATGATA
GATTCTTCTGGGCACGAAGTGACAGAAAACGATTCCGAAGACTTAAAAGCAAAATCAGGGGATGAAAAATTTTTGGAAGA
ATCCGAAAAAGCAAAACTTACGATTTTGATGGCGAAAGAATTAAAAAACCCTTCCGAAAAGAAGAAACAATTCAAAGTTA
CTTCGTATCGCGTAAAACGAAATGAAACGTTAGCCGAAATAGCAACTCGTTTTAAAGTTTCAATGGAATCCATCGCCGGT
TCTTCCAATATCAAAATCGAAGATACTCTTTATCCCGGACAAGTATTAAGTATTCCGAACAAACAAGGTCTTCTTTACAA
GATGAAAACCGGTGATACTGTCGCCAAAGTTGCGAGTCTTTACAAGGTCAATCTAGACGAAATTATGTTGGAAAACAAAT
TAGATGATCTAGATATTCTTAGACCAGGTCAGAAAGTGTTTTTACCGGGTGCAGTGATCCCCGATCCTACTCCTAAATGG
GTGATCCCAGTTGCTTCTAGAGTTGTAACTTCTAATTTCGGTTTTAGAACCTTTCCTAGAAAAAAGTTTCATGAAGGTCT
CGACTTAAAAGCATTTTACGAACCGATCGCCGCGGCTCGTAACGGTAAAGTGATTTACGCCGGTTGGATGGGTGGCTATG
GCAACGTAGTAGTAATTGAACATACGGATGATTTCAAAACCCTCTACGCACATAACTCTAAACTGTTTGTTCAAAGAGGG
GACTATGTTTTAGCAGGAAAAAAAATCGCAAGATCAGGTTCTACTGGTTATTCTTTTGGACCCCATTTACATTTCGAAGT
CATCAAAAACGGACGACCCGTTAATCCTTCCAAATACTTAAAAGGGCTTACGTTTAGAAAGGGCGGCCCTACTCACTGA

Upstream 100 bases:

>100_bases
TCTTTTGGCGGAACCAGAACCTTAGACAACGGAAAGGACGAATAAAGCTCTCTCTCTCCTCCATTAGGAAAGGGCAAAAA
GCGGCCGATATTCTTTCTAT

Downstream 100 bases:

>100_bases
TCCTCCATAGAATTTTTTAAATTAAGATTCACCCCAAAGCTAAGAGCTTGTATCTAAACCTCAAAGAATTTTATACGATA
ATTTTTTAGAAATTTTTAAT

Product: membrane metalloendopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MIFKKPRQLTAGKEILRTESFTLIYLGAFHFHYSFYFRGNLYHGNLDFRRRKFRLIPIFASVVIFLAILGFGMNPSNAMI
DSSGHEVTENDSEDLKAKSGDEKFLEESEKAKLTILMAKELKNPSEKKKQFKVTSYRVKRNETLAEIATRFKVSMESIAG
SSNIKIEDTLYPGQVLSIPNKQGLLYKMKTGDTVAKVASLYKVNLDEIMLENKLDDLDILRPGQKVFLPGAVIPDPTPKW
VIPVASRVVTSNFGFRTFPRKKFHEGLDLKAFYEPIAAARNGKVIYAGWMGGYGNVVVIEHTDDFKTLYAHNSKLFVQRG
DYVLAGKKIARSGSTGYSFGPHLHFEVIKNGRPVNPSKYLKGLTFRKGGPTH

Sequences:

>Translated_372_residues
MIFKKPRQLTAGKEILRTESFTLIYLGAFHFHYSFYFRGNLYHGNLDFRRRKFRLIPIFASVVIFLAILGFGMNPSNAMI
DSSGHEVTENDSEDLKAKSGDEKFLEESEKAKLTILMAKELKNPSEKKKQFKVTSYRVKRNETLAEIATRFKVSMESIAG
SSNIKIEDTLYPGQVLSIPNKQGLLYKMKTGDTVAKVASLYKVNLDEIMLENKLDDLDILRPGQKVFLPGAVIPDPTPKW
VIPVASRVVTSNFGFRTFPRKKFHEGLDLKAFYEPIAAARNGKVIYAGWMGGYGNVVVIEHTDDFKTLYAHNSKLFVQRG
DYVLAGKKIARSGSTGYSFGPHLHFEVIKNGRPVNPSKYLKGLTFRKGGPTH
>Mature_372_residues
MIFKKPRQLTAGKEILRTESFTLIYLGAFHFHYSFYFRGNLYHGNLDFRRRKFRLIPIFASVVIFLAILGFGMNPSNAMI
DSSGHEVTENDSEDLKAKSGDEKFLEESEKAKLTILMAKELKNPSEKKKQFKVTSYRVKRNETLAEIATRFKVSMESIAG
SSNIKIEDTLYPGQVLSIPNKQGLLYKMKTGDTVAKVASLYKVNLDEIMLENKLDDLDILRPGQKVFLPGAVIPDPTPKW
VIPVASRVVTSNFGFRTFPRKKFHEGLDLKAFYEPIAAARNGKVIYAGWMGGYGNVVVIEHTDDFKTLYAHNSKLFVQRG
DYVLAGKKIARSGSTGYSFGPHLHFEVIKNGRPVNPSKYLKGLTFRKGGPTH

Specific function: May be involved in stationary-phase survival [H]

COG id: COG0739

COG function: function code M; Membrane proteins related to metalloendopeptidases

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 LysM repeat [H]

Homologues:

Organism=Escherichia coli, GI87082174, Length=240, Percent_Identity=30, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789099, Length=123, Percent_Identity=39.0243902439024, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI87082297, Length=96, Percent_Identity=40.625, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87081989, Length=113, Percent_Identity=39.8230088495575, Blast_Score=71, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR016047
- InterPro:   IPR002886
- InterPro:   IPR018392
- InterPro:   IPR002482 [H]

Pfam domain/function: PF01476 LysM; PF01551 Peptidase_M23 [H]

EC number: NA

Molecular weight: Translated: 41973; Mature: 41973

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFKKPRQLTAGKEILRTESFTLIYLGAFHFHYSFYFRGNLYHGNLDFRRRKFRLIPIFA
CCCCCCCCHHHHHHHHHCCCEEEEEEEEEEEEEEEEEEEEEEECCCCCCCEEEEEEHHHH
SVVIFLAILGFGMNPSNAMIDSSGHEVTENDSEDLKAKSGDEKFLEESEKAKLTILMAKE
HHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCHHHCCCCCCHHHHHCCCCCEEEEEEEHH
LKNPSEKKKQFKVTSYRVKRNETLAEIATRFKVSMESIAGSSNIKIEDTLYPGQVLSIPN
CCCHHHHHHHEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEECCC
KQGLLYKMKTGDTVAKVASLYKVNLDEIMLENKLDDLDILRPGQKVFLPGAVIPDPTPKW
CCCEEEEECCCCHHHHHHHHHHCCHHHHHHHCCCCCCHHCCCCCEEEECCCCCCCCCCCE
VIPVASRVVTSNFGFRTFPRKKFHEGLDLKAFYEPIAAARNGKVIYAGWMGGYGNVVVIE
EEHHHHHHHHCCCCCCCCCHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEE
HTDDFKTLYAHNSKLFVQRGDYVLAGKKIARSGSTGYSFGPHLHFEVIKNGRPVNPSKYL
ECCCCEEEEECCCEEEEEECCEEEECCHHHCCCCCCCCCCCEEEEEEECCCCCCCHHHHH
KGLTFRKGGPTH
CCCEECCCCCCC
>Mature Secondary Structure
MIFKKPRQLTAGKEILRTESFTLIYLGAFHFHYSFYFRGNLYHGNLDFRRRKFRLIPIFA
CCCCCCCCHHHHHHHHHCCCEEEEEEEEEEEEEEEEEEEEEEECCCCCCCEEEEEEHHHH
SVVIFLAILGFGMNPSNAMIDSSGHEVTENDSEDLKAKSGDEKFLEESEKAKLTILMAKE
HHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCHHHCCCCCCHHHHHCCCCCEEEEEEEHH
LKNPSEKKKQFKVTSYRVKRNETLAEIATRFKVSMESIAGSSNIKIEDTLYPGQVLSIPN
CCCHHHHHHHEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEECCC
KQGLLYKMKTGDTVAKVASLYKVNLDEIMLENKLDDLDILRPGQKVFLPGAVIPDPTPKW
CCCEEEEECCCCHHHHHHHHHHCCHHHHHHHCCCCCCHHCCCCCEEEECCCCCCCCCCCE
VIPVASRVVTSNFGFRTFPRKKFHEGLDLKAFYEPIAAARNGKVIYAGWMGGYGNVVVIE
EEHHHHHHHHCCCCCCCCCHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEE
HTDDFKTLYAHNSKLFVQRGDYVLAGKKIARSGSTGYSFGPHLHFEVIKNGRPVNPSKYL
ECCCCEEEEECCCEEEEEECCEEEECCHHHCCCCCCCCCCCEEEEEEECCCCCCCHHHHH
KGLTFRKGGPTH
CCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9973354 [H]