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The map label for this gene is yjcC [H]

Identifier: 45658347

GI number: 45658347

Start: 3032992

End: 3034701

Strand: Reverse

Name: yjcC [H]

Synonym: LIC12505

Alternate gene names: 45658347

Gene position: 3034701-3032992 (Counterclockwise)

Preceding gene: 45658349

Following gene: 45658346

Centisome position: 70.95

GC content: 38.89

Gene sequence:

>1710_bases
ATGGACGGAAATATAAATTCTCAGGAAGAAAATAAGGATTCTAGGCCAATCATACTATTGGTAGATGACGAACCAATCAT
ATTGAGAGGACTAAAAGAACAACTTAAACTTGCGTTTGGTAAGGACTACGACATTGAAATCGCCGAAGACGCTGAAGCTG
CCTGGGAAATTTTGGAAGAATACGTAGAGAAAGGGATCGATATTCCGGTTGTAGTATGTGATCAAGTGATGCCTGGAGTA
AAAGGAGATGAGTTACTCATTCGAATTCACAATAAAAAACCGGATATACGAAAGATCATGCTTACCGGACAGGCTTCTGC
AGATGCGGTGGGTAACGCTTTAAATCACGCAAATTTATATAGATATTTATCTAAACCTTGGGATTCCAACGATTTGATCC
TTACAATTCGAGAGGCGTTAAAATCTTATTTTTCGGATCTTTCCCTTGTAGAACTCAATCGAAAATTAGAAACTACCTTA
CTTTATAACCGGGAAACGGGTCGTCCCAATTTCGAAAGTCTGAGAAAAATACTAGAAGAAAGGGAGGCTAAAGAAGCCCA
GTCTACTCTCGCCGTAATTAGAATTGAATCTTCTACTGCCACAACTCATCATTTTGGAGTAGGAGTATATCATAAAGTAC
TAAATCAACTTTTGGCGGCACTTTCTTCATTTATGGGAGACTCGGGCAGTTTATTTCATCTTTATCAGGACGAGGTAGCT
GTACTTTCCAACGTAGATGAGGATAGATTTCATTCTCTTTTGGTGGCATTTAGAATACTTCTTAGATCAGAATATATCCA
AGCGGATGGAGTTGCTTTTCGCGTAAACGTATCTATAGGAGTGGCTACCCACCAACATTCTCTTTATTATAAAGCTAGGA
TAGCGATGATGCATGCGGCTCAAAACGTTGAACTTGAACTAATGAACTATTCGCAGGCAATGGAAGAGGGGGATCAGTAT
CAGATTAATCTTATTTTAGGAAGGAAATTAAACGACGCAATACACGTAGGCAACGTAATACCTTATTTCCAGGGAATCTA
CGACAACACATTAGAGAAGATTACAAAATTTGAATGTCTTGCGAGAATTCAAGACGGAGATAGGGTATATTCTCCGGCAA
GTTTTATATCGATCGCAAGATCTACTGGGATCATTCGTCTTTTGACTCCGATCATGATTGAGAAATCGATCCGATATTTT
GCACAGTATCCGGAATATTCTTTTTCTGTGAATATATCGGAATCGGATCTGGAAAAAAAAGGATTTGCATCTTGGGTTAT
CAGTCGTTTGGAGCATTATAAGATTGTACCAGAAAGATTTACTTTAGAAATTTTAGAAACGGACCGTTTGCGTGGAGGGG
AGAGAGGACTTGAAACCTTAAAGGAATTGAAGGAATCCGGTTGTAAGATTGCGATAGACGATTTTGGAGTAGACCAATCT
AATTTTGAGAGATTGATGGAAATCGATCCAGACTTTATTAAGATAGATGGTAAATTTATACAAGGGATTCATTTGAGTAG
AACTCCATATCTGCTCACTTCTGCGATGACGGAGATGGCACATCGTATCGGAGCAAAAGTAATTGCCGAATTTGTAGCGG
GAAAAGGAGAATTTGACACGGTTCGTTCCTTAGGTGTGGAATATTGTCAGGGATATTATATTATGCAGCCCGTGCCTGAA
ATTTTTCCGATTCCTCAAGTTTCTGTTTAA

Upstream 100 bases:

>100_bases
TCAATAGAAGAACTCGGCAGGTCCTGTTCTTAGAAAAGAGACTCTGTCCGAAATAATCGTGAAAGTAGCGTTAAACGAAT
TGCCATTTTAGGAAAGTCGA

Downstream 100 bases:

>100_bases
AGAATGAAAACGTTTTTTCTAAAATTCGCTTGTCATTATTTTTTTTCTAAATAATCTAATGCTTTGCGATTTTTGACGAT
TTAGCGAGTCGAATGAATTA

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 569; Mature: 569

Protein sequence:

>569_residues
MDGNINSQEENKDSRPIILLVDDEPIILRGLKEQLKLAFGKDYDIEIAEDAEAAWEILEEYVEKGIDIPVVVCDQVMPGV
KGDELLIRIHNKKPDIRKIMLTGQASADAVGNALNHANLYRYLSKPWDSNDLILTIREALKSYFSDLSLVELNRKLETTL
LYNRETGRPNFESLRKILEEREAKEAQSTLAVIRIESSTATTHHFGVGVYHKVLNQLLAALSSFMGDSGSLFHLYQDEVA
VLSNVDEDRFHSLLVAFRILLRSEYIQADGVAFRVNVSIGVATHQHSLYYKARIAMMHAAQNVELELMNYSQAMEEGDQY
QINLILGRKLNDAIHVGNVIPYFQGIYDNTLEKITKFECLARIQDGDRVYSPASFISIARSTGIIRLLTPIMIEKSIRYF
AQYPEYSFSVNISESDLEKKGFASWVISRLEHYKIVPERFTLEILETDRLRGGERGLETLKELKESGCKIAIDDFGVDQS
NFERLMEIDPDFIKIDGKFIQGIHLSRTPYLLTSAMTEMAHRIGAKVIAEFVAGKGEFDTVRSLGVEYCQGYYIMQPVPE
IFPIPQVSV

Sequences:

>Translated_569_residues
MDGNINSQEENKDSRPIILLVDDEPIILRGLKEQLKLAFGKDYDIEIAEDAEAAWEILEEYVEKGIDIPVVVCDQVMPGV
KGDELLIRIHNKKPDIRKIMLTGQASADAVGNALNHANLYRYLSKPWDSNDLILTIREALKSYFSDLSLVELNRKLETTL
LYNRETGRPNFESLRKILEEREAKEAQSTLAVIRIESSTATTHHFGVGVYHKVLNQLLAALSSFMGDSGSLFHLYQDEVA
VLSNVDEDRFHSLLVAFRILLRSEYIQADGVAFRVNVSIGVATHQHSLYYKARIAMMHAAQNVELELMNYSQAMEEGDQY
QINLILGRKLNDAIHVGNVIPYFQGIYDNTLEKITKFECLARIQDGDRVYSPASFISIARSTGIIRLLTPIMIEKSIRYF
AQYPEYSFSVNISESDLEKKGFASWVISRLEHYKIVPERFTLEILETDRLRGGERGLETLKELKESGCKIAIDDFGVDQS
NFERLMEIDPDFIKIDGKFIQGIHLSRTPYLLTSAMTEMAHRIGAKVIAEFVAGKGEFDTVRSLGVEYCQGYYIMQPVPE
IFPIPQVSV
>Mature_569_residues
MDGNINSQEENKDSRPIILLVDDEPIILRGLKEQLKLAFGKDYDIEIAEDAEAAWEILEEYVEKGIDIPVVVCDQVMPGV
KGDELLIRIHNKKPDIRKIMLTGQASADAVGNALNHANLYRYLSKPWDSNDLILTIREALKSYFSDLSLVELNRKLETTL
LYNRETGRPNFESLRKILEEREAKEAQSTLAVIRIESSTATTHHFGVGVYHKVLNQLLAALSSFMGDSGSLFHLYQDEVA
VLSNVDEDRFHSLLVAFRILLRSEYIQADGVAFRVNVSIGVATHQHSLYYKARIAMMHAAQNVELELMNYSQAMEEGDQY
QINLILGRKLNDAIHVGNVIPYFQGIYDNTLEKITKFECLARIQDGDRVYSPASFISIARSTGIIRLLTPIMIEKSIRYF
AQYPEYSFSVNISESDLEKKGFASWVISRLEHYKIVPERFTLEILETDRLRGGERGLETLKELKESGCKIAIDDFGVDQS
NFERLMEIDPDFIKIDGKFIQGIHLSRTPYLLTSAMTEMAHRIGAKVIAEFVAGKGEFDTVRSLGVEYCQGYYIMQPVPE
IFPIPQVSV

Specific function: Overexpression reduces biofilm formation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1790496, Length=245, Percent_Identity=29.7959183673469, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI87082096, Length=423, Percent_Identity=26.241134751773, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1788849, Length=413, Percent_Identity=25.181598062954, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI226510982, Length=410, Percent_Identity=24.390243902439, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI87081743, Length=238, Percent_Identity=27.3109243697479, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI87081845, Length=238, Percent_Identity=26.890756302521, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787055, Length=245, Percent_Identity=28.1632653061224, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI87081921, Length=308, Percent_Identity=25.974025974026, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1788502, Length=246, Percent_Identity=28.4552845528455, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI87081980, Length=225, Percent_Identity=27.1111111111111, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786507, Length=228, Percent_Identity=24.1228070175439, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1787541, Length=214, Percent_Identity=25.2336448598131, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 64552; Mature: 64552

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGNINSQEENKDSRPIILLVDDEPIILRGLKEQLKLAFGKDYDIEIAEDAEAAWEILEE
CCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHH
YVEKGIDIPVVVCDQVMPGVKGDELLIRIHNKKPDIRKIMLTGQASADAVGNALNHANLY
HHHCCCCCEEEEHHHHCCCCCCCEEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHH
RYLSKPWDSNDLILTIREALKSYFSDLSLVELNRKLETTLLYNRETGRPNFESLRKILEE
HHHCCCCCCCCCEEEHHHHHHHHHCCCHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHH
REAKEAQSTLAVIRIESSTATTHHFGVGVYHKVLNQLLAALSSFMGDSGSLFHLYQDEVA
HHHHHHHCEEEEEEEECCCCCCHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHH
VLSNVDEDRFHSLLVAFRILLRSEYIQADGVAFRVNVSIGVATHQHSLYYKARIAMMHAA
HHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCHHHHHHHHHHHHHHC
QNVELELMNYSQAMEEGDQYQINLILGRKLNDAIHVGNVIPYFQGIYDNTLEKITKFECL
CCCEEEEECHHHHHCCCCCEEEEEEECCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHH
ARIQDGDRVYSPASFISIARSTGIIRLLTPIMIEKSIRYFAQYPEYSFSVNISESDLEKK
HHHCCCCCEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHH
GFASWVISRLEHYKIVPERFTLEILETDRLRGGERGLETLKELKESGCKIAIDDFGVDQS
HHHHHHHHHHHHCEECCCCEEEEEEHHHHCCCCHHHHHHHHHHHHCCCEEEEECCCCCHH
NFERLMEIDPDFIKIDGKFIQGIHLSRTPYLLTSAMTEMAHRIGAKVIAEFVAGKGEFDT
HHHHHHHCCCCEEEECCEEEECEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VRSLGVEYCQGYYIMQPVPEIFPIPQVSV
HHHHHHHHHCCEEEECCCCHHCCCCCCCC
>Mature Secondary Structure
MDGNINSQEENKDSRPIILLVDDEPIILRGLKEQLKLAFGKDYDIEIAEDAEAAWEILEE
CCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHH
YVEKGIDIPVVVCDQVMPGVKGDELLIRIHNKKPDIRKIMLTGQASADAVGNALNHANLY
HHHCCCCCEEEEHHHHCCCCCCCEEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHH
RYLSKPWDSNDLILTIREALKSYFSDLSLVELNRKLETTLLYNRETGRPNFESLRKILEE
HHHCCCCCCCCCEEEHHHHHHHHHCCCHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHH
REAKEAQSTLAVIRIESSTATTHHFGVGVYHKVLNQLLAALSSFMGDSGSLFHLYQDEVA
HHHHHHHCEEEEEEEECCCCCCHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHH
VLSNVDEDRFHSLLVAFRILLRSEYIQADGVAFRVNVSIGVATHQHSLYYKARIAMMHAA
HHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCHHHHHHHHHHHHHHC
QNVELELMNYSQAMEEGDQYQINLILGRKLNDAIHVGNVIPYFQGIYDNTLEKITKFECL
CCCEEEEECHHHHHCCCCCEEEEEEECCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHH
ARIQDGDRVYSPASFISIARSTGIIRLLTPIMIEKSIRYFAQYPEYSFSVNISESDLEKK
HHHCCCCCEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHH
GFASWVISRLEHYKIVPERFTLEILETDRLRGGERGLETLKELKESGCKIAIDDFGVDQS
HHHHHHHHHHHHCEECCCCEEEEEEHHHHCCCCHHHHHHHHHHHHCCCEEEEECCCCCHH
NFERLMEIDPDFIKIDGKFIQGIHLSRTPYLLTSAMTEMAHRIGAKVIAEFVAGKGEFDT
HHHHHHHCCCCEEEECCEEEECEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VRSLGVEYCQGYYIMQPVPEIFPIPQVSV
HHHHHHHHHCCEEEECCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]