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The map label for this gene is 45658321

Identifier: 45658321

GI number: 45658321

Start: 3004088

End: 3004942

Strand: Direct

Name: 45658321

Synonym: LIC12479

Alternate gene names: NA

Gene position: 3004088-3004942 (Clockwise)

Preceding gene: 45658312

Following gene: 45658323

Centisome position: 70.24

GC content: 36.02

Gene sequence:

>855_bases
TTGTCTTTGAATTCCGAGGAGAAATCATGTTCCTCTATGACAGGAATCTACAATCGAATCGGCCCGGAGCTGACTCCAGT
AGTCCGTACCTTATTGATTTTAAACGGGAGTATCTTTGCGGTTCAACTTCTACTTTCCTGGACGGTAGGAGATTACCTAA
CTCTTTATTTTGGAATGACTTCCGATATGATCACTCACCGTTTTTTTATTTGGCAATTTCTGACATACGCATTCCTACAC
TCCGTTCAAAATTTCTTTCACATCTTATTCAATATGTTTTCTCTTTGGATGTTTGGTTCGGTTTTAGAAAGTTACTGGGG
TAGTAGAAATTTTTTGAAGTTTTATTTATTCTCTTGTTTTATGGGGGGTTTTTTTCCTTGGATTTTGCATAACGTTGGAT
TTCATCAAGGTACAATCATTGGCGCTTCCGGTGGAATCTACGGTCTTTTGATCGCTTTCGCTTTGATTTGGCCTAACCAA
GAACTTCTTTTTATGGGCTTTTTTCCTCTTAAAGCAAAGTATATGGTTGTAATTCTTATGCTCATCATTGCGTTTTCAGG
TTCTGGTAGCAACATCGCACACATGGCTCATTTGGGTGGAGCAATAGGTGGAGCGATTTATTTCTTTTATTATAATAAAC
TAAAGTCTAAAATTCCTGCTTCTTTGTCTCTCAGTCGTTACCTTCAGAAAAGAAAGATGAAAAAATGGCAAGAAGAAATG
AATCGTAAAATTCATGTCAGAGAAGAAGTAGATCAGTTATTGGATAAAATTTCTAAATCCGGTATGAATTCTCTTTCTAG
AAAAGAAAAAAAATTTTTGAAAGAAGCTTCGAGTAAGTATTACTCAGAAGATTGA

Upstream 100 bases:

>100_bases
ACCTCTGGTTCCGTATAACTGAACGATCATATCCGGCCCAGTATTTAACTTCCGAAATTTTCTGTCAAAGAGAAGAGAAA
CAAGAAATTCCGTTTTACGG

Downstream 100 bases:

>100_bases
TTTTTTTAGTTCTTATCCAAAGCTATCTATATTAACAGAAAACAATCCAATCGTTTACACATCCATCCTGTAAATTCAGC
GTAAAAAATTTGAACAAAAT

Product: cytoplasmic membrane protein

Products: NA

Alternate protein names: Transmembrane Rhomboid Family Protein; Peptidase; Cytoplasmic Membrane Protein; Integral Membrane Protein; Rhomboid-Like Protein; Membrane Serine Protease; GlpG Protein; Serine Protease; Rhomboid Family Membrane Protein; Membrane Associated Serine Protease Rhomboid Family

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MSLNSEEKSCSSMTGIYNRIGPELTPVVRTLLILNGSIFAVQLLLSWTVGDYLTLYFGMTSDMITHRFFIWQFLTYAFLH
SVQNFFHILFNMFSLWMFGSVLESYWGSRNFLKFYLFSCFMGGFFPWILHNVGFHQGTIIGASGGIYGLLIAFALIWPNQ
ELLFMGFFPLKAKYMVVILMLIIAFSGSGSNIAHMAHLGGAIGGAIYFFYYNKLKSKIPASLSLSRYLQKRKMKKWQEEM
NRKIHVREEVDQLLDKISKSGMNSLSRKEKKFLKEASSKYYSED

Sequences:

>Translated_284_residues
MSLNSEEKSCSSMTGIYNRIGPELTPVVRTLLILNGSIFAVQLLLSWTVGDYLTLYFGMTSDMITHRFFIWQFLTYAFLH
SVQNFFHILFNMFSLWMFGSVLESYWGSRNFLKFYLFSCFMGGFFPWILHNVGFHQGTIIGASGGIYGLLIAFALIWPNQ
ELLFMGFFPLKAKYMVVILMLIIAFSGSGSNIAHMAHLGGAIGGAIYFFYYNKLKSKIPASLSLSRYLQKRKMKKWQEEM
NRKIHVREEVDQLLDKISKSGMNSLSRKEKKFLKEASSKYYSED
>Mature_283_residues
SLNSEEKSCSSMTGIYNRIGPELTPVVRTLLILNGSIFAVQLLLSWTVGDYLTLYFGMTSDMITHRFFIWQFLTYAFLHS
VQNFFHILFNMFSLWMFGSVLESYWGSRNFLKFYLFSCFMGGFFPWILHNVGFHQGTIIGASGGIYGLLIAFALIWPNQE
LLFMGFFPLKAKYMVVILMLIIAFSGSGSNIAHMAHLGGAIGGAIYFFYYNKLKSKIPASLSLSRYLQKRKMKKWQEEMN
RKIHVREEVDQLLDKISKSGMNSLSRKEKKFLKEASSKYYSED

Specific function: Unknown

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Saccharomyces cerevisiae, GI6321538, Length=199, Percent_Identity=29.6482412060301, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 32728; Mature: 32597

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SLNSEEKSCSSMTGIYNRIGPELTPVVRTLLILNGSIFAVQLLLSWTVGDYLTLYFGMT
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCH
SDMITHRFFIWQFLTYAFLHSVQNFFHILFNMFSLWMFGSVLESYWGSRNFLKFYLFSCF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
MGGFFPWILHNVGFHQGTIIGASGGIYGLLIAFALIWPNQELLFMGFFPLKAKYMVVILM
HHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHH
LIIAFSGSGSNIAHMAHLGGAIGGAIYFFYYNKLKSKIPASLSLSRYLQKRKMKKWQEEM
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
NRKIHVREEVDQLLDKISKSGMNSLSRKEKKFLKEASSKYYSED
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA