| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
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The map label for this gene is purQ
Identifier: 45658248
GI number: 45658248
Start: 2909727
End: 2911964
Strand: Reverse
Name: purQ
Synonym: LIC12402
Alternate gene names: 45658248
Gene position: 2911964-2909727 (Counterclockwise)
Preceding gene: 45658249
Following gene: 45658247
Centisome position: 68.08
GC content: 40.66
Gene sequence:
>2238_bases ATGGAAAAAGACGTCGTTTCCTTAGAAGACGCCCTGGAGCACGGGCTTACCAAAGAAGAATTTCAAAAGATTCAAGAAAT TTTAGGAAGAATTCCAAATTCTACCGAACTTGGAATTTTTTCCGCGATGTGGTCGGAACACTGTTCTTATAAAAACTCGA TTCTAAAATTAAAAACTCTTCCGACAACCTCAGATAAACTACTTGCAAAAGCAGGAGAAGAAAACGCTGGAGCAATGGAT ATAGGTGACGGCTTAGCAGTGGTTTTCAAAATAGAAAGCCATAATCATCCTACGGCTGTAGAACCGTATCAGGGAGCAGC GACTGGTGTAGGTGGAATTATGAGAGATATTTTTACGATGGGCGCTCGTCCGATCGTATCTCTCAATTCACTTCGTTTTG GAAATCCGGATGAACCTAAAAATAAATATCTACTTTCTCGTGCGGTAAAGGGAATCGGAGACTACGGAAACTCACTTGGA ATTGCAGTGTCGGGTGGAGAACTTTTTATAGATGAATGTTTTTCCAAAAATCCACTCGTAAATGCAATGACCGTCGGGGT TGTGCGTCATGATCAGATGGCGAGTGCGACTACGGGTGGACAAGTTGGTAACTCTGTTTACATCGTAGGAGCTACGACCG GAAGGGACGGAATTCACGGAGCTTCTTTTGCATCCAAGGATCTTTCCAAAGAATCTGAATCGAAACGATCTGCGGTGCAA GTAGGGGATCCGTTTATGGAAAAGCTCTTGATGGAAGCAAGTTTAGAAGCGATTCAGAAAGGACTTCTCGTAGGAATTCA AGACATGGGTGCTGCCGGAATTTCTTGTGCTACTTCCGAAATGAGCGCCAAAGGAAAAACCGGAATGAAGATCGATTTAG ATCTTGTTCCATTTAGAGAAACCGGAATGAACGCATACGAAGCGATGTTATCCGAATCTCAAGAAAGAATGTTGGTCGTA CCTAAAAAGGGAAAAGAATCGGAACTCGTATCAATATTCGAAAAATGGAATTTAAACGCGGTCAAGATCGGAGAAGTTAC AGCAGATGGAATGATCGAAATTTATATGGGCGGAAAACTGAAAGCTAAAATTCCTGCCGAATCACTTGTGTTAGGTGGAG GAGCTCCCCGTTACGAAAGAGAAACCAAACGTCCTTCATATCTGGATGCGGTCAAAACTTGGAAACCAGATGAGATTCCC GACGTGACCAAAGGTGCAAATTCAAAAGAGATATTGCTCAAAATTCTTTCTTCTTGGAATGTGTGTTCTAGAAAACCGAT CACGGAACAATATGATAGTGAAGTTGGTTTAGTAAAACTCATCGGTCCCGGTTTAGACGGGGGACTTTCCGCTATTCCCG GTACAAATAAAGCACTTGCAACTGCAACCGATTGTAATTCCAGATATACGTATTTAGATCCTTATAAAGGTGCGGAATTT GCCGTATGTGAAGCAGCTCGAAATGTGTATGTGACCGGTGCAACTCCTTACGGAGTGACTAATAATCTTAATTTTGCAAA TCCTTATATTCCTGAAAACTACTATATATTTTCTGAATGTATTCGTGGAATGGGCGACGCTTGTCGTTTTCTGGGACTTC CTGTGACGGGTGGTAATGTATCTTTTTACAATGAATCTCCGGAAGGTCCAATTTTTCCAACTCCTACGATTGGTATGGTG GGAATTTTAGAAAATAAGGAAAAACTTATATTCAATTTTCCGAAAGAAATCGGGGTTGAACTTGCGGTTCTGGGAAATTT TCGTCCTTCTCTCGGGGGAAGTGAATATTTGAAAAAAATCCACGGTCAAATCAACGGAAGTATTCCCGAGTTGGATATTA AAGAAGAATTAGAACTTTGTAAACTAATCCTTTCCTTGAATGAAAGTAGAATTTTAAAATCTGCGAAAGATCTTTCTTTG GGAGGAATTGCAGTAGCACTTTCTAAAACGGTACTTTTTTCGGGGTTAGGAATTGAGTCTGACCTAACGTCTCTTAGACG GAACAGATTGGATTTGACCCTTTTTGGAGAAAGTTCGACAGCGGTTTTGGTAGGATTTGATTCGTTATCGAAAGAAGACA TTCGTAAACAGACTGAAGCTTATGGATTAAAGTTCTATCCGATAGGAAAAACAAATTCTTCCGGAATTTTAGAAATCAAA GACGCCGAAATTAAAATTTCTTTCCAGGAATTGAGCGGACCTTATGAAAAAGGTTTAGAGGCGGTTTTTGCATTATAA
Upstream 100 bases:
>100_bases CTCTACAAAACTACGAACGGGAAATTGGGTCCGAACTACGCCCTAATTTTATGGAATATTTGATTTTCAGAGTGCGACTT AGAAAAAATACTGACAAACG
Downstream 100 bases:
>100_bases AAAAGGATCAAACCAATGAATTTCCTATCTTTAAAAAAAATCTTTAAGCTCTATTTCTTTCTTTGGGTTTCGTTTTTTGG GATCGATTGTAAAAAAAACG
Product: phosphoribosylformylglycinamidine synthase II
Products: NA
Alternate protein names: Phosphoribosylformylglycinamidine synthase II; FGAM synthase II [H]
Number of amino acids: Translated: 745; Mature: 745
Protein sequence:
>745_residues MEKDVVSLEDALEHGLTKEEFQKIQEILGRIPNSTELGIFSAMWSEHCSYKNSILKLKTLPTTSDKLLAKAGEENAGAMD IGDGLAVVFKIESHNHPTAVEPYQGAATGVGGIMRDIFTMGARPIVSLNSLRFGNPDEPKNKYLLSRAVKGIGDYGNSLG IAVSGGELFIDECFSKNPLVNAMTVGVVRHDQMASATTGGQVGNSVYIVGATTGRDGIHGASFASKDLSKESESKRSAVQ VGDPFMEKLLMEASLEAIQKGLLVGIQDMGAAGISCATSEMSAKGKTGMKIDLDLVPFRETGMNAYEAMLSESQERMLVV PKKGKESELVSIFEKWNLNAVKIGEVTADGMIEIYMGGKLKAKIPAESLVLGGGAPRYERETKRPSYLDAVKTWKPDEIP DVTKGANSKEILLKILSSWNVCSRKPITEQYDSEVGLVKLIGPGLDGGLSAIPGTNKALATATDCNSRYTYLDPYKGAEF AVCEAARNVYVTGATPYGVTNNLNFANPYIPENYYIFSECIRGMGDACRFLGLPVTGGNVSFYNESPEGPIFPTPTIGMV GILENKEKLIFNFPKEIGVELAVLGNFRPSLGGSEYLKKIHGQINGSIPELDIKEELELCKLILSLNESRILKSAKDLSL GGIAVALSKTVLFSGLGIESDLTSLRRNRLDLTLFGESSTAVLVGFDSLSKEDIRKQTEAYGLKFYPIGKTNSSGILEIK DAEIKISFQELSGPYEKGLEAVFAL
Sequences:
>Translated_745_residues MEKDVVSLEDALEHGLTKEEFQKIQEILGRIPNSTELGIFSAMWSEHCSYKNSILKLKTLPTTSDKLLAKAGEENAGAMD IGDGLAVVFKIESHNHPTAVEPYQGAATGVGGIMRDIFTMGARPIVSLNSLRFGNPDEPKNKYLLSRAVKGIGDYGNSLG IAVSGGELFIDECFSKNPLVNAMTVGVVRHDQMASATTGGQVGNSVYIVGATTGRDGIHGASFASKDLSKESESKRSAVQ VGDPFMEKLLMEASLEAIQKGLLVGIQDMGAAGISCATSEMSAKGKTGMKIDLDLVPFRETGMNAYEAMLSESQERMLVV PKKGKESELVSIFEKWNLNAVKIGEVTADGMIEIYMGGKLKAKIPAESLVLGGGAPRYERETKRPSYLDAVKTWKPDEIP DVTKGANSKEILLKILSSWNVCSRKPITEQYDSEVGLVKLIGPGLDGGLSAIPGTNKALATATDCNSRYTYLDPYKGAEF AVCEAARNVYVTGATPYGVTNNLNFANPYIPENYYIFSECIRGMGDACRFLGLPVTGGNVSFYNESPEGPIFPTPTIGMV GILENKEKLIFNFPKEIGVELAVLGNFRPSLGGSEYLKKIHGQINGSIPELDIKEELELCKLILSLNESRILKSAKDLSL GGIAVALSKTVLFSGLGIESDLTSLRRNRLDLTLFGESSTAVLVGFDSLSKEDIRKQTEAYGLKFYPIGKTNSSGILEIK DAEIKISFQELSGPYEKGLEAVFAL >Mature_745_residues MEKDVVSLEDALEHGLTKEEFQKIQEILGRIPNSTELGIFSAMWSEHCSYKNSILKLKTLPTTSDKLLAKAGEENAGAMD IGDGLAVVFKIESHNHPTAVEPYQGAATGVGGIMRDIFTMGARPIVSLNSLRFGNPDEPKNKYLLSRAVKGIGDYGNSLG IAVSGGELFIDECFSKNPLVNAMTVGVVRHDQMASATTGGQVGNSVYIVGATTGRDGIHGASFASKDLSKESESKRSAVQ VGDPFMEKLLMEASLEAIQKGLLVGIQDMGAAGISCATSEMSAKGKTGMKIDLDLVPFRETGMNAYEAMLSESQERMLVV PKKGKESELVSIFEKWNLNAVKIGEVTADGMIEIYMGGKLKAKIPAESLVLGGGAPRYERETKRPSYLDAVKTWKPDEIP DVTKGANSKEILLKILSSWNVCSRKPITEQYDSEVGLVKLIGPGLDGGLSAIPGTNKALATATDCNSRYTYLDPYKGAEF AVCEAARNVYVTGATPYGVTNNLNFANPYIPENYYIFSECIRGMGDACRFLGLPVTGGNVSFYNESPEGPIFPTPTIGMV GILENKEKLIFNFPKEIGVELAVLGNFRPSLGGSEYLKKIHGQINGSIPELDIKEELELCKLILSLNESRILKSAKDLSL GGIAVALSKTVLFSGLGIESDLTSLRRNRLDLTLFGESSTAVLVGFDSLSKEDIRKQTEAYGLKFYPIGKTNSSGILEIK DAEIKISFQELSGPYEKGLEAVFAL
Specific function: Unknown
COG id: COG0046
COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the FGAMS family [H]
Homologues:
Organism=Escherichia coli, GI48994899, Length=776, Percent_Identity=24.6134020618557, Blast_Score=114, Evalue=2e-26, Organism=Caenorhabditis elegans, GI17553022, Length=397, Percent_Identity=25.4408060453401, Blast_Score=72, Evalue=9e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000728 - InterPro: IPR010918 - InterPro: IPR010074 - InterPro: IPR016188 [H]
Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]
EC number: =6.3.5.3 [H]
Molecular weight: Translated: 80332; Mature: 80332
Theoretical pI: Translated: 5.12; Mature: 5.12
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.6 %Met (Mature Protein) 3.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MEKDVVSLEDALEHGLTKEEFQKIQEILGRIPNSTELGIFSAMWSEHCSYKNSILKLKTL CCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEC PTTSDKLLAKAGEENAGAMDIGDGLAVVFKIESHNHPTAVEPYQGAATGVGGIMRDIFTM CCCHHHHHHHCCCCCCCCEECCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH GARPIVSLNSLRFGNPDEPKNKYLLSRAVKGIGDYGNSLGIAVSGGELFIDECFSKNPLV CCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCEEEHHHHCCCCCCC NAMTVGVVRHDQMASATTGGQVGNSVYIVGATTGRDGIHGASFASKDLSKESESKRSAVQ EEEEEEEEECCHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHEE VGDPFMEKLLMEASLEAIQKGLLVGIQDMGAAGISCATSEMSAKGKTGMKIDLDLVPFRE CCCHHHHHHHHHHHHHHHHHHHEEEEHHCCCCCCEEECHHHCCCCCCCCEEEEEEECCHH TGMNAYEAMLSESQERMLVVPKKGKESELVSIFEKWNLNAVKIGEVTADGMIEIYMGGKL HCCHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCCEEEECCCCCCCEEEEEECCEE KAKIPAESLVLGGGAPRYERETKRPSYLDAVKTWKPDEIPDVTKGANSKEILLKILSSWN EECCCHHHEEECCCCCCCCHHCCCCHHHHHHHCCCCCCCCCHHCCCCHHHHHHHHHHCCC VCSRKPITEQYDSEVGLVKLIGPGLDGGLSAIPGTNKALATATDCNSRYTYLDPYKGAEF CCCCCCCHHHHCCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCEEECCCCCCCH AVCEAARNVYVTGATPYGVTNNLNFANPYIPENYYIFSECIRGMGDACRFLGLPVTGGNV HEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEHHHHHHCCCHHHHHHCCEECCCCE SFYNESPEGPIFPTPTIGMVGILENKEKLIFNFPKEIGVELAVLGNFRPSLGGSEYLKKI EEECCCCCCCCCCCCCCCEEEEECCCCEEEEECCHHHCEEEEEEECCCCCCCHHHHHHHH HGQINGSIPELDIKEELELCKLILSLNESRILKSAKDLSLGGIAVALSKTVLFSGLGIES HHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHH DLTSLRRNRLDLTLFGESSTAVLVGFDSLSKEDIRKQTEAYGLKFYPIGKTNSSGILEIK HHHHHHHCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHCCEEEEECCCCCCCCEEEEE DAEIKISFQELSGPYEKGLEAVFAL CCEEEEEHHHHCCCHHHHHHHHHCC >Mature Secondary Structure MEKDVVSLEDALEHGLTKEEFQKIQEILGRIPNSTELGIFSAMWSEHCSYKNSILKLKTL CCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEC PTTSDKLLAKAGEENAGAMDIGDGLAVVFKIESHNHPTAVEPYQGAATGVGGIMRDIFTM CCCHHHHHHHCCCCCCCCEECCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH GARPIVSLNSLRFGNPDEPKNKYLLSRAVKGIGDYGNSLGIAVSGGELFIDECFSKNPLV CCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCEEEHHHHCCCCCCC NAMTVGVVRHDQMASATTGGQVGNSVYIVGATTGRDGIHGASFASKDLSKESESKRSAVQ EEEEEEEEECCHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHEE VGDPFMEKLLMEASLEAIQKGLLVGIQDMGAAGISCATSEMSAKGKTGMKIDLDLVPFRE CCCHHHHHHHHHHHHHHHHHHHEEEEHHCCCCCCEEECHHHCCCCCCCCEEEEEEECCHH TGMNAYEAMLSESQERMLVVPKKGKESELVSIFEKWNLNAVKIGEVTADGMIEIYMGGKL HCCHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCCEEEECCCCCCCEEEEEECCEE KAKIPAESLVLGGGAPRYERETKRPSYLDAVKTWKPDEIPDVTKGANSKEILLKILSSWN EECCCHHHEEECCCCCCCCHHCCCCHHHHHHHCCCCCCCCCHHCCCCHHHHHHHHHHCCC VCSRKPITEQYDSEVGLVKLIGPGLDGGLSAIPGTNKALATATDCNSRYTYLDPYKGAEF CCCCCCCHHHHCCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCEEECCCCCCCH AVCEAARNVYVTGATPYGVTNNLNFANPYIPENYYIFSECIRGMGDACRFLGLPVTGGNV HEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEHHHHHHCCCHHHHHHCCEECCCCE SFYNESPEGPIFPTPTIGMVGILENKEKLIFNFPKEIGVELAVLGNFRPSLGGSEYLKKI EEECCCCCCCCCCCCCCCEEEEECCCCEEEEECCHHHCEEEEEEECCCCCCCHHHHHHHH HGQINGSIPELDIKEELELCKLILSLNESRILKSAKDLSLGGIAVALSKTVLFSGLGIES HHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHH DLTSLRRNRLDLTLFGESSTAVLVGFDSLSKEDIRKQTEAYGLKFYPIGKTNSSGILEIK HHHHHHHCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHCCEEEEECCCCCCCCEEEEE DAEIKISFQELSGPYEKGLEAVFAL CCEEEEEHHHHCCCHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA