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The map label for this gene is crp [C]

Identifier: 45658234

GI number: 45658234

Start: 2893576

End: 2894103

Strand: Reverse

Name: crp [C]

Synonym: LIC12388

Alternate gene names: 45658234

Gene position: 2894103-2893576 (Counterclockwise)

Preceding gene: 45658235

Following gene: 45658233

Centisome position: 67.66

GC content: 38.64

Gene sequence:

>528_bases
TTGAAGGCTCTTGATCTTCCTATCTGGAAAAAATTATTCATTCGTAAAGAAGCGAGTAATCAAGAGATCATTCGATTTCT
CAGGGAAACTTCTGTTTTTGGAAGGATGAAAAAAAGAACCTTAATCGAAATCGCTAGGATGATTCACGTTCGAGAATATC
AGGAAGGAGAAACCGTATTTAGACAGGGGGAAGTAGGAGCCGGTTTTTATTTAGTTTATGAAGGTTCGGTAGTGATTCGT
TCCGTTCGGGATGGAATTGAATTGGATCTTGCTCATTTAGATAGGCACGCGTTTTTTGGAGAACTTTCTCTTTTTACGGA
AGAAAGAAGAACTGCGAGTGCTTTTGCTCTTGAAAAGACGACTCTACTTGGTTTTTTTCAACCGGATCTTAAAGAAATTA
TAGAAACAAAACCTAGGATCGGAATCGAAATTCTAATGAGTTTATCGACTGTGATCGTGGAAAGATTGCATAGAACCAAC
GGACTTTTGGAAAAAGCGTACTTCCGGGGAAAACAGAAAAATGCGTGA

Upstream 100 bases:

>100_bases
TTTTCTAGATGGCCTGCGTTTAACGTAGCCGATTCTTGTGTCACGATTGGTCTTACGATTTTGATCTTTACGATGAAACT
AGAAGAGGAGAAATAATTTT

Downstream 100 bases:

>100_bases
GGGAGAAAGAAGAGAACTTTCCGAATATTTTATTCGGACTAGTTTTTTTCTGATCGTTATTTTTACGATCGTTGTTTCTC
TGTGGGGGCTCCATTTACTT

Product: cyclic nucleotide binding protein

Products: NA

Alternate protein names: Transcriptional Regulator Crp/Fnr Family; CRP/FNR Family Transcriptional Regulator; Crp Family Transcriptional Regulator; Transcriptional Regulator; Crp/FNR Family Transcriptional Regulator; CAMP-Dependent Protein Kinase

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MKALDLPIWKKLFIRKEASNQEIIRFLRETSVFGRMKKRTLIEIARMIHVREYQEGETVFRQGEVGAGFYLVYEGSVVIR
SVRDGIELDLAHLDRHAFFGELSLFTEERRTASAFALEKTTLLGFFQPDLKEIIETKPRIGIEILMSLSTVIVERLHRTN
GLLEKAYFRGKQKNA

Sequences:

>Translated_175_residues
MKALDLPIWKKLFIRKEASNQEIIRFLRETSVFGRMKKRTLIEIARMIHVREYQEGETVFRQGEVGAGFYLVYEGSVVIR
SVRDGIELDLAHLDRHAFFGELSLFTEERRTASAFALEKTTLLGFFQPDLKEIIETKPRIGIEILMSLSTVIVERLHRTN
GLLEKAYFRGKQKNA
>Mature_175_residues
MKALDLPIWKKLFIRKEASNQEIIRFLRETSVFGRMKKRTLIEIARMIHVREYQEGETVFRQGEVGAGFYLVYEGSVVIR
SVRDGIELDLAHLDRHAFFGELSLFTEERRTASAFALEKTTLLGFFQPDLKEIIETKPRIGIEILMSLSTVIVERLHRTN
GLLEKAYFRGKQKNA

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 20319; Mature: 20319

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS00889 CNMP_BINDING_2 ; PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALDLPIWKKLFIRKEASNQEIIRFLRETSVFGRMKKRTLIEIARMIHVREYQEGETVF
CCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RQGEVGAGFYLVYEGSVVIRSVRDGIELDLAHLDRHAFFGELSLFTEERRTASAFALEKT
HCCCCCCCEEEEEECHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLLGFFQPDLKEIIETKPRIGIEILMSLSTVIVERLHRTNGLLEKAYFRGKQKNA
HHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCC
>Mature Secondary Structure
MKALDLPIWKKLFIRKEASNQEIIRFLRETSVFGRMKKRTLIEIARMIHVREYQEGETVF
CCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RQGEVGAGFYLVYEGSVVIRSVRDGIELDLAHLDRHAFFGELSLFTEERRTASAFALEKT
HCCCCCCCEEEEEECHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLLGFFQPDLKEIIETKPRIGIEILMSLSTVIVERLHRTNGLLEKAYFRGKQKNA
HHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA