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The map label for this gene is lldD [H]

Identifier: 45658117

GI number: 45658117

Start: 2739843

End: 2742125

Strand: Reverse

Name: lldD [H]

Synonym: LIC12268

Alternate gene names: 45658117

Gene position: 2742125-2739843 (Counterclockwise)

Preceding gene: 45658118

Following gene: 304570509

Centisome position: 64.11

GC content: 42.05

Gene sequence:

>2283_bases
TTGTCTCTAAGTCATAAAATTACTGGAAAGACGATTTTGATCGTAGGAGGGGGGCTTTTACAGGTTCCCATCATTCAAAC
CTCTAAAATGATGAAACTTACCACCGTAGTCGCAGATATGAATGGTGAAGCTCCTGGTATGAAAATTTGCGACATTCCTA
TGGTAATGAGCACGAAAGATATTGAAGGAATGGTAAGAGAATCCAAAAAACTCTCCACTAAAATCAAAATCGACGGAGTG
ATTACTGCCGGAACCGATGCGAGTATGACCGTGGCCGCGGTTGCAAATGCTCTCGATCTCCCTGGAATTCGATATGTGGA
TGCGGAAGCCGCTTCTAACAAAGTAAAAATGCGGGAACGTTTGAAAAAAGCAGGAATTCCTCTCCCCGGTTTTGCTCCTG
TGTGGAGTCTTTCCGATACAAGAGACGCATTAGAATTTTTGAATTTTCCACTCGTGATGAAACCCGCGGACAACATGGGT
GCTCGGGGGGTTATCAAAGTAGAAAATAGGGAAGAGTTACAAGCGGCGTTTAAACACGCAAAAAAATATTCTCCTACGGG
AGAGATGATTTTAGAAGAATATATGCCCGGTCCGGAAGTTTCTGTGGACGCTCTCACTTGGAATGGGAATTTTGTAATCA
CTGGAATCGCAGATAGAATTATTGAAAGAGAACCTTATTTTATAGAGATGGGGCATAACATGCCTTCTGCTTTGAGTCCT
TCTATTTTAAAAGAAGTGGAAGAGGTGATGTTTCGAAGTATGAAGGCTCTTGGAATTACTCTTGGAGCTGGAAAGGGAGA
TATTAAAGTTACTCCGGATGGAGTTAAGGTAGGGGAAATTGCCGCGAGATTATCCGGTGGTTTTATGTCTGCGTTCACTT
TTCCTCTTTCTTCTGGAATTAACTTAAATCGGGCCGCCATCTTAATCGCGTTAGGTGAAGAGCCGGACAACTTGACTCCT
ACCTCCAATAGAATTTCGATAGAACGTTGTCTTTTAGCTCCGAGAGGAAAACTTATTTCCATCGATGGAATTGAGGAGAC
TCGTAAGATAGAAGGGGTCAACGATCTGTTTTTTATGAATAAGATCGGGGATATTATCCAAGAACCTACGAATAACATAG
AAAAAACGGGACACGTAATTATCAGCGCGGATACTTTGGAGCAAGCTGAGACGGTTTTTGAAAAAGTAAAAAATACGATT
CGATTTACTTGTGACGAACTCTATTCTGTTTCCGAAAAAGAAATTCAACAAAATGCCAGATTACGTTTTGGAAAAGAAGT
ATGCTGGGTTTGTAAAGTTTGTGACGGAACCGATTGTGCTTCCGGGGTTCCTGGGATGGGCGCTCTGGGAAAAATGCTTA
CTTTTCAAGACAATATCAATGCACTACGGGAATATTCGATTCTTCCTAAATATATTCGAGAACATACTCAGGCTTCGGTA
GAAGCTCACTTTCTTGGAAAAAAATTTAGAACCCCTGTAATGGCAGCTCCGATGACTGGAGCTGTTACGAATATGAACGG
CGCCATGGATGAGTTTACGTTTGCGGCTACTCTGCTGGAGGGATGTCATACTTCTGGCACCTTGGCATGGTTAGGCGATG
GCGCCAGTCCGGAAAAATATTTGATCATGTTGGAAGCGATTCGTAAAACAAAGGCGGACGCGGTTTTGATCTGTAAACCT
AGAGAAGACGAAGGGCTTTTAAAAGAAAGATTTCAAGAATCCGAAAAATCCGGTCTTTTGGCGATCGGTATGGACGTAGA
CGCGGTCAATTTTAAGACGATGACTTTGAAAAATATTTCCTCGATTACTAGAAATGTTTCTAAACTTGCGAAAATTCGTT
CTTTTACTAAGTTACCTTTTATCGTCAAAGGTATCATGGCCCCACAGGACGCACAGCTTGCAATCGATGCAGGTGCGGAT
TGTATCGTCGTATCCAATCACGGAGGAAGAGTTTTAGACGATATGCCCGGAACTGCTAGAGTTCTTTCTGGAATTAGAAA
TGTTATAGGTGATAAGATTCAGATTGTGGCAGATGGTGGAGTGAGAAGCGGCATGGACGTATTTAAAATGATCGCTTTGG
GTGCGGATACGGTTCTAGTGGGAAGACCGATGGCGATTTTTGCGGTTGGAGGTGGAGTTGCCGGAGTTCGATTTTTAATT
TCACAATATACTGATAATCTTTTACAGTCTATGAATGTTACTGGAACCGAAACTTTGAAAGATATTGGAATGGAGTTACT
CTTTCGGAAAAAAATTGACGAAGAAAATTCTCCGACTGAATGA

Upstream 100 bases:

>100_bases
GATTATTTATTGTTAGGCGGAATTATCTCCAAGGGAAGTATTCAAATGCGGGTTGCGGAACCTGCGATTTCTGTCTTAAA
TTGAACGAGGATTTTCTTTT

Downstream 100 bases:

>100_bases
GAAAATCGTTTTACTAACTTAAAATTTACGGTTTAATATTCGAACCGTAAATCTACGGGTCGTGTTCGGACGAAAGAATC
ATGGATAAGTTTATCAATGA

Product: putative glycolate oxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 760; Mature: 759

Protein sequence:

>760_residues
MSLSHKITGKTILIVGGGLLQVPIIQTSKMMKLTTVVADMNGEAPGMKICDIPMVMSTKDIEGMVRESKKLSTKIKIDGV
ITAGTDASMTVAAVANALDLPGIRYVDAEAASNKVKMRERLKKAGIPLPGFAPVWSLSDTRDALEFLNFPLVMKPADNMG
ARGVIKVENREELQAAFKHAKKYSPTGEMILEEYMPGPEVSVDALTWNGNFVITGIADRIIEREPYFIEMGHNMPSALSP
SILKEVEEVMFRSMKALGITLGAGKGDIKVTPDGVKVGEIAARLSGGFMSAFTFPLSSGINLNRAAILIALGEEPDNLTP
TSNRISIERCLLAPRGKLISIDGIEETRKIEGVNDLFFMNKIGDIIQEPTNNIEKTGHVIISADTLEQAETVFEKVKNTI
RFTCDELYSVSEKEIQQNARLRFGKEVCWVCKVCDGTDCASGVPGMGALGKMLTFQDNINALREYSILPKYIREHTQASV
EAHFLGKKFRTPVMAAPMTGAVTNMNGAMDEFTFAATLLEGCHTSGTLAWLGDGASPEKYLIMLEAIRKTKADAVLICKP
REDEGLLKERFQESEKSGLLAIGMDVDAVNFKTMTLKNISSITRNVSKLAKIRSFTKLPFIVKGIMAPQDAQLAIDAGAD
CIVVSNHGGRVLDDMPGTARVLSGIRNVIGDKIQIVADGGVRSGMDVFKMIALGADTVLVGRPMAIFAVGGGVAGVRFLI
SQYTDNLLQSMNVTGTETLKDIGMELLFRKKIDEENSPTE

Sequences:

>Translated_760_residues
MSLSHKITGKTILIVGGGLLQVPIIQTSKMMKLTTVVADMNGEAPGMKICDIPMVMSTKDIEGMVRESKKLSTKIKIDGV
ITAGTDASMTVAAVANALDLPGIRYVDAEAASNKVKMRERLKKAGIPLPGFAPVWSLSDTRDALEFLNFPLVMKPADNMG
ARGVIKVENREELQAAFKHAKKYSPTGEMILEEYMPGPEVSVDALTWNGNFVITGIADRIIEREPYFIEMGHNMPSALSP
SILKEVEEVMFRSMKALGITLGAGKGDIKVTPDGVKVGEIAARLSGGFMSAFTFPLSSGINLNRAAILIALGEEPDNLTP
TSNRISIERCLLAPRGKLISIDGIEETRKIEGVNDLFFMNKIGDIIQEPTNNIEKTGHVIISADTLEQAETVFEKVKNTI
RFTCDELYSVSEKEIQQNARLRFGKEVCWVCKVCDGTDCASGVPGMGALGKMLTFQDNINALREYSILPKYIREHTQASV
EAHFLGKKFRTPVMAAPMTGAVTNMNGAMDEFTFAATLLEGCHTSGTLAWLGDGASPEKYLIMLEAIRKTKADAVLICKP
REDEGLLKERFQESEKSGLLAIGMDVDAVNFKTMTLKNISSITRNVSKLAKIRSFTKLPFIVKGIMAPQDAQLAIDAGAD
CIVVSNHGGRVLDDMPGTARVLSGIRNVIGDKIQIVADGGVRSGMDVFKMIALGADTVLVGRPMAIFAVGGGVAGVRFLI
SQYTDNLLQSMNVTGTETLKDIGMELLFRKKIDEENSPTE
>Mature_759_residues
SLSHKITGKTILIVGGGLLQVPIIQTSKMMKLTTVVADMNGEAPGMKICDIPMVMSTKDIEGMVRESKKLSTKIKIDGVI
TAGTDASMTVAAVANALDLPGIRYVDAEAASNKVKMRERLKKAGIPLPGFAPVWSLSDTRDALEFLNFPLVMKPADNMGA
RGVIKVENREELQAAFKHAKKYSPTGEMILEEYMPGPEVSVDALTWNGNFVITGIADRIIEREPYFIEMGHNMPSALSPS
ILKEVEEVMFRSMKALGITLGAGKGDIKVTPDGVKVGEIAARLSGGFMSAFTFPLSSGINLNRAAILIALGEEPDNLTPT
SNRISIERCLLAPRGKLISIDGIEETRKIEGVNDLFFMNKIGDIIQEPTNNIEKTGHVIISADTLEQAETVFEKVKNTIR
FTCDELYSVSEKEIQQNARLRFGKEVCWVCKVCDGTDCASGVPGMGALGKMLTFQDNINALREYSILPKYIREHTQASVE
AHFLGKKFRTPVMAAPMTGAVTNMNGAMDEFTFAATLLEGCHTSGTLAWLGDGASPEKYLIMLEAIRKTKADAVLICKPR
EDEGLLKERFQESEKSGLLAIGMDVDAVNFKTMTLKNISSITRNVSKLAKIRSFTKLPFIVKGIMAPQDAQLAIDAGADC
IVVSNHGGRVLDDMPGTARVLSGIRNVIGDKIQIVADGGVRSGMDVFKMIALGADTVLVGRPMAIFAVGGGVAGVRFLIS
QYTDNLLQSMNVTGTETLKDIGMELLFRKKIDEENSPTE

Specific function: Unknown

COG id: COG0439

COG function: function code I; Biotin carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI54234014, Length=334, Percent_Identity=27.8443113772455, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI7705393, Length=334, Percent_Identity=27.8443113772455, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI11068137, Length=335, Percent_Identity=26.5671641791045, Blast_Score=106, Evalue=9e-23,
Organism=Homo sapiens, GI148839342, Length=362, Percent_Identity=24.0331491712707, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI261245046, Length=362, Percent_Identity=24.0331491712707, Blast_Score=70, Evalue=1e-11,
Organism=Escherichia coli, GI1790033, Length=141, Percent_Identity=43.2624113475177, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI193208036, Length=134, Percent_Identity=39.5522388059701, Blast_Score=101, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6323587, Length=145, Percent_Identity=34.4827586206897, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI78707188, Length=134, Percent_Identity=37.3134328358209, Blast_Score=98, Evalue=3e-20,
Organism=Drosophila melanogaster, GI281363140, Length=134, Percent_Identity=37.3134328358209, Blast_Score=98, Evalue=3e-20,
Organism=Drosophila melanogaster, GI78707190, Length=134, Percent_Identity=37.3134328358209, Blast_Score=98, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 82371; Mature: 82240

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS50975 ATP_GRASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSHKITGKTILIVGGGLLQVPIIQTSKMMKLTTVVADMNGEAPGMKICDIPMVMSTKD
CCCCCEECCCEEEEECCCEEEEEEECCCHHHEEEEEEEECCCCCCCCEEECCCEEECCHH
IEGMVRESKKLSTKIKIDGVITAGTDASMTVAAVANALDLPGIRYVDAEAASNKVKMRER
HHHHHHHHHHCCEEEEEEEEEEECCCCCHHHHHHHHHHCCCCCEEEECHHHCCHHHHHHH
LKKAGIPLPGFAPVWSLSDTRDALEFLNFPLVMKPADNMGARGVIKVENREELQAAFKHA
HHHCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEECCCCCCCCCEEEECCHHHHHHHHHHH
KKYSPTGEMILEEYMPGPEVSVDALTWNGNFVITGIADRIIEREPYFIEMGHNMPSALSP
HCCCCHHHHHHHHHCCCCCCEEEEEEECCCEEEEEHHHHHHCCCCCEEEECCCCCCCCCH
SILKEVEEVMFRSMKALGITLGAGKGDIKVTPDGVKVGEIAARLSGGFMSAFTFPLSSGI
HHHHHHHHHHHHHHHHHEEEEECCCCCEEECCCCCCHHHHHHHHCCCHHHHHHHHHCCCC
NLNRAAILIALGEEPDNLTPTSNRISIERCLLAPRGKLISIDGIEETRKIEGVNDLFFMN
CCCCEEEEEEECCCCCCCCCCCCCEEHHHHHCCCCCCEEEECCCHHHHHHCCCHHHHHHH
KIGDIIQEPTNNIEKTGHVIISADTLEQAETVFEKVKNTIRFTCDELYSVSEKEIQQNAR
HHHHHHHCCCCCHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LRFGKEVCWVCKVCDGTDCASGVPGMGALGKMLTFQDNINALREYSILPKYIREHTQASV
HHCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHH
EAHFLGKKFRTPVMAAPMTGAVTNMNGAMDEFTFAATLLEGCHTSGTLAWLGDGASPEKY
HHHHHHHHHCCCEEECCCCCCEECCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHH
LIMLEAIRKTKADAVLICKPREDEGLLKERFQESEKSGLLAIGMDVDAVNFKTMTLKNIS
HHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCEEEEEHHHHH
SITRNVSKLAKIRSFTKLPFIVKGIMAPQDAQLAIDAGADCIVVSNHGGRVLDDMPGTAR
HHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEECCCCEEEEECCCCEEECCCCCHHH
VLSGIRNVIGDKIQIVADGGVRSGMDVFKMIALGADTVLVGRPMAIFAVGGGVAGVRFLI
HHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEECCCEEEEEECCCHHHHHHHH
SQYTDNLLQSMNVTGTETLKDIGMELLFRKKIDEENSPTE
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SLSHKITGKTILIVGGGLLQVPIIQTSKMMKLTTVVADMNGEAPGMKICDIPMVMSTKD
CCCCEECCCEEEEECCCEEEEEEECCCHHHEEEEEEEECCCCCCCCEEECCCEEECCHH
IEGMVRESKKLSTKIKIDGVITAGTDASMTVAAVANALDLPGIRYVDAEAASNKVKMRER
HHHHHHHHHHCCEEEEEEEEEEECCCCCHHHHHHHHHHCCCCCEEEECHHHCCHHHHHHH
LKKAGIPLPGFAPVWSLSDTRDALEFLNFPLVMKPADNMGARGVIKVENREELQAAFKHA
HHHCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEECCCCCCCCCEEEECCHHHHHHHHHHH
KKYSPTGEMILEEYMPGPEVSVDALTWNGNFVITGIADRIIEREPYFIEMGHNMPSALSP
HCCCCHHHHHHHHHCCCCCCEEEEEEECCCEEEEEHHHHHHCCCCCEEEECCCCCCCCCH
SILKEVEEVMFRSMKALGITLGAGKGDIKVTPDGVKVGEIAARLSGGFMSAFTFPLSSGI
HHHHHHHHHHHHHHHHHEEEEECCCCCEEECCCCCCHHHHHHHHCCCHHHHHHHHHCCCC
NLNRAAILIALGEEPDNLTPTSNRISIERCLLAPRGKLISIDGIEETRKIEGVNDLFFMN
CCCCEEEEEEECCCCCCCCCCCCCEEHHHHHCCCCCCEEEECCCHHHHHHCCCHHHHHHH
KIGDIIQEPTNNIEKTGHVIISADTLEQAETVFEKVKNTIRFTCDELYSVSEKEIQQNAR
HHHHHHHCCCCCHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LRFGKEVCWVCKVCDGTDCASGVPGMGALGKMLTFQDNINALREYSILPKYIREHTQASV
HHCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHH
EAHFLGKKFRTPVMAAPMTGAVTNMNGAMDEFTFAATLLEGCHTSGTLAWLGDGASPEKY
HHHHHHHHHCCCEEECCCCCCEECCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHH
LIMLEAIRKTKADAVLICKPREDEGLLKERFQESEKSGLLAIGMDVDAVNFKTMTLKNIS
HHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCEEEEEHHHHH
SITRNVSKLAKIRSFTKLPFIVKGIMAPQDAQLAIDAGADCIVVSNHGGRVLDDMPGTAR
HHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEECCCCEEEEECCCCEEECCCCCHHH
VLSGIRNVIGDKIQIVADGGVRSGMDVFKMIALGADTVLVGRPMAIFAVGGGVAGVRFLI
HHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEECCCEEEEEECCCHHHHHHHH
SQYTDNLLQSMNVTGTETLKDIGMELLFRKKIDEENSPTE
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA